Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method von Chen, Guo-Bo, Lee, Sang Hong, Montgomery, Grant W, Wray, Naomi R, Visscher, Peter M, Gearry, Richard B, Lawrance, Ian C, Andrews, Jane M, Bampton, Peter, Mahy, Gillian, Bell, Sally, Walsh, Alissa, Connor, Susan, Sparrow, Miles, Bowdler, Lisa M, Simms, Lisa A, Krishnaprasad, Krupa, Radford-Smith, Graham L, Moser, Gerhard

Volltext

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study von Cleynen, Isabelle, PhD, Boucher, Gabrielle, MSc, Jostins, Luke, PhD, Schumm, L Philip, MA, Zeissig, Sebastian, PhD, Ahmad, Tariq, PhD, Andersen, Vibeke, Prof, Andrews, Jane M, Prof, Annese, Vito, MD, Brand, Stephan, Prof, Brant, Steven R, MD, Cho, Judy H, Prof, Daly, Mark J, Prof, Dubinsky, Marla, MD, Duerr, Richard H, Prof, Ferguson, Lynnette R, Prof, Franke, Andre, Prof, Gearry, Richard B, Prof, Goyette, Philippe, PhD, Hakonarson, Hakon, Prof, Halfvarson, Jonas, MD, Hov, Johannes R, PhD, Huang, Hailang, PhD, Kennedy, Nicholas A, PhD, Kupcinskas, Limas, Prof, Lawrance, Ian C, Prof, Lee, James C, PhD, Satsangi, Jack, Prof, Schreiber, Stephan, Prof, Théâtre, Emilie, PhD, van der Meulen-de Jong, Andrea E, MD, Weersma, Rinse K, Prof, Wilson, David C, Prof, Parkes, Miles, PhD, Vermeire, Severine, Prof, Rioux, John D, Prof, Mansfield, John, MD, Silverberg, Mark S, PhD, Radford-Smith, Graham, PhD, McGovern, Dermot P B, Prof, Barrett, Jeffrey C, Dr, Lees, Charlie W, Dr

Volltext

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs von Lee, S Hong, Ripke, Stephan, Neale, Benjamin M, Faraone, Stephen V, Purcell, Shaun M, Perlis, Roy H, Mowry, Bryan J, Thapar, Anita, Goddard, Michael E, Witte, John S, Absher, Devin, Agartz, Ingrid, Akil, Huda, Amin, Farooq, Andreassen, Ole A, Anjorin, Adebayo, Anney, Richard, Anttila, Verneri, Arking, Dan E, Asherson, Philip, Azevedo, Maria H, Backlund, Lena, Badner, Judith A, Bailey, Anthony J, Banaschewski, Tobias, Barchas, Jack D, Barnes, Michael R, Barrett, Thomas B, Bass, Nicholas, Battaglia, Agatino, Bauer, Michael, Bayés, Mònica, Bellivier, Frank, Bergen, Sarah E, Berrettini, Wade, Betancur, Catalina, Bettecken, Thomas, Biederman, Joseph, Binder, Elisabeth B, Black, Donald W, Blackwood, Douglas H R, Bloss, Cinnamon S, Boehnke, Michael, Boomsma, Dorret I, Breen, Gerome, Breuer, René, Bruggeman, Richard, Cormican, Paul, Buccola, Nancy G, Buitelaar, Jan K, Bunney, William E, Buxbaum, Joseph D, Byerley, William F, Byrne, Enda M, Caesar, Sian, Cahn, Wiepke, Cantor, Rita M, Casas, Miguel, Chakravarti, Aravinda, Chambert, Kimberly, Choudhury, Khalid, Cichon, Sven, Cloninger, C Robert, Collier, David A, Cook, Edwin H, Coon, Hilary, Cormand, Bru, Corvin, Aiden, Coryell, William H, Craig, David W, Craig, Ian W, Crosbie, Jennifer, Cuccaro, Michael L, Curtis, David, Czamara, Darina, Datta, Susmita, Dawson, Geraldine, Day, Richard, De Geus, Eco J, Degenhardt, Franziska, Djurovic, Srdjan, Donohoe, Gary J, Doyle, Alysa E, Duan, Jubao, Dudbridge, Frank, Duketis, Eftichia, Ebstein, Richard P, Edenberg, Howard J, Elia, Josephine, Ennis, Sean, Etain, Bruno, Fanous, Ayman, Farmer, Anne E, Ferrier, I Nicol, Flickinger, Matthew, Fombonne, Eric, Foroud, Tatiana, Frank, Josef, Franke, Barbara, Fraser, Christine

Volltext

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease von Jostins, Luke, Ripke, Stephan, Weersma, Rinse K., Duerr, Richard H., McGovern, Dermot P., Hui, Ken Y., Lee, James C., Philip Schumm, L., Sharma, Yashoda, Anderson, Carl A., Mitrovic, Mitja, Ning, Kaida, Cleynen, Isabelle, Theatre, Emilie, Raychaudhuri, Soumya, Goyette, Philippe, Wei, Zhi, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Amininejad, Leila, Ananthakrishnan, Ashwin N., Andersen, Vibeke, Andrews, Jane M., Baidoo, Leonard, Balschun, Tobias, Bampton, Peter A., Bitton, Alain, Boucher, Gabrielle, Brand, Stephan, Büning, Carsten, Cohain, Ariella, Cichon, Sven, D’Amato, Mauro, De Jong, Dirk, Dubinsky, Marla, Edwards, Cathryn, Ellinghaus, David, Ferguson, Lynnette R., Franchimont, Denis, Fransen, Karin, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hedl, Matija, Hu, Xinli, Karlsen, Tom H., Kupcinskas, Limas, Kugathasan, Subra, Latiano, Anna, Laukens, Debby, Lawrance, Ian C., Lees, Charlie W., Louis, Edouard, Mahy, Gillian, Mansfield, John, Morgan, Angharad R., Mowat, Craig, Newman, William, Palmieri, Orazio, Ponsioen, Cyriel Y., Potocnik, Uros, Prescott, Natalie J., Rotter, Jerome I., Sanderson, Jeremy D., Sans, Miquel, Schreiber, Stefan, Simms, Lisa A., Sventoraityte, Jurgita, Targan, Stephan R., Taylor, Kent D., Tremelling, Mark, Verspaget, Hein W., De Vos, Martine, Wijmenga, Cisca, Wilson, David C., Winkelmann, Juliane, Xavier, Ramnik J., Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K., Zhao, Hongyu, Silverberg, Mark S., Annese, Vito, Hakonarson, Hakon, Brant, Steven R., Radford-Smith, Graham, Mathew, Christopher G., Rioux, John D., Schadt, Eric E., Daly, Mark J., Franke, Andre, Parkes, Miles, Vermeire, Severine, Barrett, Jeffrey C., Cho, Judy H

Volltext

IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes von Momozawa, Yukihide, Dmitrieva, Julia, Théâtre, Emilie, Deffontaine, Valérie, Rahmouni, Souad, Charloteaux, Benoît, Crins, François, Docampo, Elisa, Elansary, Mahmoud, Gori, Ann-Stephan, Lecut, Christelle, Mariman, Rob, Mni, Myriam, Oury, Cécile, Altukhov, Ilya, Alexeev, Dmitry, Aulchenko, Yuri, Amininejad, Leila, Bouma, Gerd, Hoentjen, Frank, Löwenberg, Mark, Oldenburg, Bas, Pierik, Marieke J., vander Meulen-de Jong, Andrea E., Janneke van der Woude, C., Visschedijk, Marijn C., Lathrop, Mark, Hugot, Jean-Pierre, Weersma, Rinse K., De Vos, Martine, Franchimont, Denis, Vermeire, Severine, Kubo, Michiaki, Louis, Edouard, Georges, Michel

Volltext

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis von Liu, Jimmy Z, Hov, Johannes Roksund, Folseraas, Trine, Ellinghaus, Eva, Rushbrook, Simon M, Doncheva, Nadezhda T, Andreassen, Ole A, Weersma, Rinse K, Weismüller, Tobias J, Eksteen, Bertus, Invernizzi, Pietro, Hirschfield, Gideon M, Gotthardt, Daniel Nils, Pares, Albert, Ellinghaus, David, Shah, Tejas, Juran, Brian D, Milkiewicz, Piotr, Rust, Christian, Schramm, Christoph, Müller, Tobias, Srivastava, Brijesh, Dalekos, Georgios, Nöthen, Markus M, Herms, Stefan, Winkelmann, Juliane, Mitrovic, Mitja, Braun, Felix, Ponsioen, Cyriel Y, Croucher, Peter J P, Sterneck, Martina, Teufel, Andreas, Mason, Andrew L, Saarela, Janna, Leppa, Virpi, Dorfman, Ruslan, Alvaro, Domenico, Floreani, Annarosa, Onengut-Gumuscu, Suna, Rich, Stephen S, Thompson, Wesley K, Schork, Andrew J, Næss, Sigrid, Thomsen, Ingo, Mayr, Gabriele, König, Inke R, Hveem, Kristian, Cleynen, Isabelle, Gutierrez-Achury, Javier, Ricaño-Ponce, Isis, van Heel, David, Björnsson, Einar, Sandford, Richard N, Durie, Peter R, Melum, Espen, Vatn, Morten H, Silverberg, Mark S, Duerr, Richard H, Padyukov, Leonid, Brand, Stephan, Sans, Miquel, Annese, Vito, Achkar, Jean-Paul, Boberg, Kirsten Muri, Marschall, Hanns-Ulrich, Chazouillères, Olivier, Bowlus, Christopher L, Wijmenga, Cisca, Schrumpf, Erik, Vermeire, Severine, Albrecht, Mario, Rioux, John D, Alexander, Graeme, Bergquist, Annika, Cho, Judy, Schreiber, Stefan, Manns, Michael P, Färkkilä, Martti, Dale, Anders M, Chapman, Roger W, Lazaridis, Konstantinos N, Franke, Andre, Anderson, Carl A, Karlsen, Tom H

Volltext

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data von Romagnoni, Alberto, Jégou, Simon, Van Steen, Kristel, Wainrib, Gilles, Hugot, Jean-Pierre

Volltext

Higher Anti-tumor Necrosis Factor-α Levels Correlate With Improved Radiologic Outcomes in Crohn’s Perianal Fistulas von De Gregorio, Michael, Lee, Tanya, Krishnaprasad, Krupa, Amos, Gregory, An, Yoon-Kyo, Bastian-Jordan, Matthew, Begun, Jakob, Borok, Nira, Brown, Dougal J.M., Cheung, Wa, Connor, Susan J., Gerstenmaier, Jan, Gilbert, Lauren E., Gilmore, Robert, Gu, Bonita, Kutaiba, Numan, Lee, Allan, Mahy, Gillian, Srinivasan, Ashish, Thin, Lena, Thompson, Alexander J., Welman, Christopher J., Yong, Eric X.Z., De Cruz, Peter, van Langenberg, Daniel, Sparrow, Miles P., Ding, Nik S.

Volltext

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population von Rivas, Manuel A, Avila, Brandon E, Koskela, Jukka, Huang, Hailiang, Stevens, Christine, Pirinen, Matti, Haritunians, Talin, Neale, Benjamin M, Kurki, Mitja, Ganna, Andrea, Graham, Daniel, Glaser, Benjamin, Peter, Inga, Atzmon, Gil, Barzilai, Nir, Levine, Adam P, Schiff, Elena, Pontikos, Nikolas, Weisburd, Ben, Lek, Monkol, Karczewski, Konrad J, Bloom, Jonathan, Minikel, Eric V, Petersen, Britt-Sabina, Beaugerie, Laurent, Seksik, Philippe, Cosnes, Jacques, Schreiber, Stefan, Bokemeyer, Bernd, Bethge, Johannes, Heap, Graham, Ahmad, Tariq, Plagnol, Vincent, Segal, Anthony W, Targan, Stephan, Turner, Dan, Saavalainen, Paivi, Farkkila, Martti, Kontula, Kimmo, Palotie, Aarno, Brant, Steven R, Duerr, Richard H, Silverberg, Mark S, Rioux, John D, Weersma, Rinse K, Franke, Andre, Jostins, Luke, Anderson, Carl A, Barrett, Jeffrey C, MacArthur, Daniel G, Jalas, Chaim, Sokol, Harry, Xavier, Ramnik J, Pulver, Ann, Cho, Judy H, McGovern, Dermot P B, Daly, Mark J

Volltext

HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis von Schwerk, Maria, Padoan, Benedetta, Schloer, Sebastian, Zecher, Britta F., Malsy, Jakob, Joshi, Vinita R., Möller, Kimberly J., Flomm, Jäger, Julia, Reinshagen, Konrad, Sandfort, Deborah, Steinert, Fenja, Tomuschat, Christian, Martin, Maureen P., Yuki, Yuko, Sauter, Jürgen, Schmidt, Alexander H., Giannou, Anastasios D., Sauter, Guido, Franke, Andre, Abraham, Clara, Achkar, Jean-Paul, Alizadeh, Behrooz, Amininejad, Leila, Andersen, Vibeke, Andrews, Jane M., Baidoo, Leonard, Baldassano, Robert N., Bampton, Peter A., Bewshea, Claire, BK, Thelma, Brain, Oliver, Brand, Stephan, Cheon, Jae Hee, Chew, Angela, Cohain, Ariella, Croft, Anthony, D'Amato, Mauro, Danese, Silvio, Daryani, Naser Ebrahim, Datta, Lisa Wu, Dubinsky, Marla, Duerr, Richard H., Edwards, Cathryn, Esaki, Motohiro, Franchimont, Denis, Franke, Andre, Georges, Michel, Gieger, Christian, Glas, Jürgen, Green, Todd, Guthery, Stephen L., Hakonarson, Hakon, Hanigan, Katherine, Hayward, Nicholas K., Hong, Myhunghee, Hu, Xinli, Jazayeri, Omid, Chandra Juyal, Ramesh, Karlsen, Tom H., Kennedy, Nicholas A., Kiudelis, Gediminas, Lamb, Christopher A., de Lange, Katrina M., Leja, Marcis, Lewis, Nina, Van Limbergen, Johan, Louis, Edouard, Mansfield, John, Mowat, Craig, Nöthen, Markus, Okou, David, Orchard, Timothy R., Parkes, Miles, Prescott, Natalie J., Rahier, Jean- Francois, Regueiro, Miguel, Rieder, Florian, Schadt, Eric E., Scharl, Michael, Scott, Regan, Sharma, Yashoda, Simms, Lisa A., Song, Kyuyoung, Sood, Ajit, Spain, Sarah L., Stronati, Laura, Sung, Joseph J.Y., Torres, Esther A., Vasiliauskas, Eric, Verspaget, Hein W., De Vos, Martine, Wang, Kai, Wang, Ming-Hsi, Wei, Zhi, Whiteman, David, Wilson, David C., Zhang, Hu, Zhang, Wei, Bunders, Madeleine J.

Volltext

Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn’s disease and leads to impaired CFB cleavage and phagocytosis von Stamps, Dalton T, Dube, Shishir, Li, Dalin, Yang, Shaohong, Landers, Carol J, Mengesha, Emebet, Murali, Ramachandran, Potdar, Alka A, Wolf, Andrea J, Botwin, Gregory J, Khrom, Michelle, Faubion, William A, Sandler, Robert S, Sartor, R Balfour, Brant, Steven R, Rioux, John D, Schumm, L Philip, Silverberg, Mark S, Zaghiyan, Karen, Melmed, Gil Y, Vasiliauskas, Eric A, Syal, Gaurav, Bonthala, Nirupama N, Targan, Stephan R, Michelsen, Kathrin S, Ahmad, Tariq, Amininejad, Leila, Andersen, Vibeke, Aumais, Guy, Baidoo, Leonard, Bayless, Theodore M, Bethge, Johannes, Boucher, Gabrielle, Brand, Stephan, Chew, Angela, Cho, Judy H, Cohain, Ariella, Jong, Dirk De, Denson, Lee A, Dewit, Olivier, D'Inca, Renata, Edwards, Cathryn, Ellinghaus, David, Festen, Eleonora A, Florin, Tim, Gieger, Christian, Goyette, Philippe, Green, Todd, Griffiths, Anne M, Hakonarson, Hakon, Hanigan, Katherine, Hart, Ailsa, Hayward, Nicholas K, Hugot, Jean-Pierre, Hui, Ken Y, Imielinski, Marcin, Jonaitis, Laimas, Jostins, Luke, Kiudelis, Gediminas, Krishnaprasad, Krupa, Kugathasan, Subra, Lee, James C, Lees, Charlie W, Leja, Marcis, Louis, Edouard, Mitrovic, Mitja, Ng, Aylwin, Ng, Siew C, Evelyn Ng, Sok Meng, Nikolaus, Susanna, Oikonomou, Ioannis, Phillips, Anne, Ponsioen, Cyriel Y, Prescott, Natalie J, Raychaudhuri, Soumya, Rieder, Florian, Rioux, John D, Ripke, Stephan, Russell, Richard K, Sanderson, Jeremy D, Satsangi, Jack, Schreiber, Stefan, Philip Schumm, L, Scott, Regan, Silverberg, Mark S, Simms, Lisa A, Spain, Sarah L, Sventoraityte, Jurgita, Torkvist, Leif, Tremelling, Mark, Vasiliauskas, Eric, Vermeire, Severine, Walters, Thomas, Wang, Kai, Wang, Ming-Hsi, Wei, Zhi, Winkelmann, Juliane, Zhang, Clarence K, Zhang, Wei, Zhao, Zhen Z

Volltext

Malignant Range Elevation of Serum Chromogranin A due to Inadvertent Use of Proton Pump Inhibitor in a Subject with Pancreatic Incidentaloma von Malabu, Usman Hammawa, Karamatic, Rozemary, Mahy, Gillian, Sangla, Kunwarjit Singh

Volltext

Vedolizumab for ulcerative colitis: Real world outcomes from a multicenter observational cohort of Australia and Oxford von Pulusu, Samba Siva Reddy, Srinivasan, Ashish, Krishnaprasad, Krupa, Cheng, Daniel, Begun, Jakob, Keung, Charlotte, Van Langenberg, Daniel, Thin, Lena, Mogilevski, Tamara, De Cruz, Peter, Radford-Smith, Graham, Flanagan, Emma, Bell, Sally, Kashkooli, Soleiman, Sparrow, Miles, Ghaly, Simon, Bampton, Peter, Sawyer, Elise, Connor, Susan, Rizvi, Quart-ul-ain, Andrews, Jane M., Mahy, Gillian, Chivers, Paola, Travis, Simon, Lawrance, Ian Craig

Volltext

Su437 HIGHER ANTI-TUMOUR NECROSIS FACTOR-ALPHA DRUG LEVELS ARE ASSOCIATED WITH IMPROVED RADIOLOGICAL OUTCOMES IN PATIENTS WITH PERIANAL FISTULISING CROHN'S DISEASE: A MULTICENTRE C... von De Gregorio, Michael, Lee, Tanya, Krishnaprasad, Krupa, Amos, Gregory, An, Yoon-Kyo, Bastian-Jordan, Matthew, Begun, Jakob, Borok, Nira, Brown, Dougal J., Cheung, Wa, Connor, Susan J., Gerstenmaier, Jan F., Gilbert, Lauren, Gilmore, Robert, Gu, Bonita, Kutaiba, Numan, Lee, Allan, Mahy, Gillian, Srinivasan, Ashish, Thin, Lena, Thompson, Alexander, Welman, Christopher J., Yong, Eric, De Cruz, Peter, Van Langenberg, Daniel R., Sparrow, Miles, Ding, Nik S.

Volltext

An Extremes of Phenotype Approach Confirms Significant Genetic Heterogeneity in Patients with Ulcerative Colitis von Mortlock, Sally, Lord, Anton, Montgomery, Grant, Zakrzewski, Martha, Simms, Lisa A, Krishnaprasad, Krupa, Hanigan, Katherine, Doecke, James D, Walsh, Alissa, Lawrance, Ian C, Bampton, Peter A, Andrews, Jane M, Mahy, Gillian, Connor, Susan J, Sparrow, Miles P, Bell, Sally, Florin, Timothy H, Begun, Jakob, Gearry, Richard B, Radford-Smith, Graham L

Volltext

Tu1807 - Genetically Distinct Signatures of Mild and Severe Ulcerative Colitis von Lord, Anton, Mortlock, Sally, Montgomery, Grant, Simms, Lisa, Krishnaprasad, Krupa, Hanigan, Katherine, Doecke, James D., Gearry, Richard, Lawrance, Ian, Bampton, Peter A., Andrews, Jane M., Mahy, Gillian, Connor, Susan J., Sparrow, Miles, Bell, Sally, Walsh, Alissa, Radford-Smith, Graham L.

Volltext

Su1909 - Crohn's Disease Patients with at Least 1 Nod2 Mutations and Who Smoke Regularly are Four Times as Likely to Need two or more Resections von Lord, Anton, Baird, Angela, Simms, Lisa, Krishnaprasad, Krupa, Hanigan, Katherine, Doecke, James D., Gearry, Richard, Bampton, Peter A., Andrews, Jane M., Mahy, Gillian, Radford-Smith, Graham L., Lawrance, Ian

Volltext

Rare case of sclerosing mesenteritis and low grade follicular lymphoma von Shah, Seema, Mahy, Gillian, Roche, Enrico

Volltext

Mo1879 - Vedolizumab(VDZ) Real World Outcomes in Ulcerative Colitis (UC) von Pulusu, Samba Siva Reddy, Srinivasan, Ashish, Krishnaprasad, Krupa, Cheng, Daniel, Mogilevski, Tamara, Flanagan, Emma, Keung, Charlotte, Wu, Yang, Prosser, Ruth, Sawyer, Elise A., Rizvi, Quart-Ul-Ain, Su, Heidi Y., Leung, Wai K., Edmundson, Aleksandra, Cooke, Sharon, Mahy, Gillian, Thin, Lena, Radford-Smith, Graham L., Sparrow, Miles, Andrews, Jane M., Connor, Susan J., Bampton, Peter A., Simon, Ghaly, van Langenberg, Daniel R., Bell, Sally, De Cruz, Peter, Begun, Jakob, Ng, Siew C., Travis, Simon P., Lawrance, Ian

Volltext

A Retrospective Observational Analysis of Food Bolus Impaction (FBI) Presentations Within Regional Australia (Rural North Queensland) von Karamatic, Rozemary, Lawlor, Jenine, Croese, John, Mahy, Gillian

Volltext