Combination cancer immunotherapy and new immunomodulatory targets von Mahoney, Kathleen M., Rennert, Paul D., Freeman, Gordon J.

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The Next Immune-Checkpoint Inhibitors: PD-1/PD-L1 Blockade in Melanoma von Mahoney, Kathleen M., MD, PhD, Freeman, Gordon J., PhD, McDermott, David F., MD

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Learning from PD-1 Resistance: New Combination Strategies von Bu, Xia, Mahoney, Kathleen M, Freeman, Gordon J

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irRECIST for the Evaluation of Candidate Biomarkers of Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma: Analysis of a Phase II Prospective Clinical Trial von Pignon, Jean-Christophe, Jegede, Opeyemi, Shukla, Sachet A, Braun, David A, Horak, Christine E, Wind-Rotolo, Megan, Ishii, Yuko, Catalano, Paul J, Grosha, Jonian, Flaifel, Abdallah, Novak, Jesse S, Mahoney, Kathleen M, Freeman, Gordon J, Sharpe, Arlene H, Hodi, F Stephen, Motzer, Robert J, Choueiri, Toni K, Wu, Catherine J, Atkins, Michael B, McDermott, David F, Signoretti, Sabina

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The importance of exosomal PDL1 in tumour immune evasion von Daassi, Dhouha, Mahoney, Kathleen M., Freeman, Gordon J.

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Soluble PD-L1 as an early marker of progressive disease on nivolumab von Mahoney, Kathleen M, Ross-Macdonald, Petra, Yuan, Long, Song, Linan, Veras, Eliseo, Wind-Rotolo, Megan, McDermott, David F, Stephen Hodi, F, Choueiri, Toni K, Freeman, Gordon J

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Regulation of HHLA2 expression in kidney cancer and myeloid cells von Shigemura, Tomonari, Perrot, Nahuel, Huang, Zimo, Bhatt, Rupal S, Sheshdeh, Aseman Bagheri, Ahmar, Nourhan El, Ghandour, Fatme, Signoretti, Sabina, McDermott, David F, Freeman, Gordon J, Mahoney, Kathleen M

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PD-L1 Antibodies to Its Cytoplasmic Domain Most Clearly Delineate Cell Membranes in Immunohistochemical Staining of Tumor Cells von Mahoney, Kathleen M, Sun, Heather, Liao, Xiaoyun, Hua, Ping, Callea, Marcella, Greenfield, Edward A, Hodi, F Stephen, Sharpe, Arlene H, Signoretti, Sabina, Rodig, Scott J, Freeman, Gordon J

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Leukemia vaccine overcomes limitations of checkpoint blockade by evoking clonal T-cell responses in a murine acute myeloid leukemia model von Stroopinsky, Dina, Liegel, Jessica, Bhasin, Manoj, Cheloni, Giulia, Thomas, Beena, Bhasin, Swati, Panchal, Ruchit, Ghiasuddin, Haider, Rahimian, Maryam, Nahas, Myrna, Orr, Shira, Capelletti, Marzia, Torres, Daniela, Tacettin, Cansu, Weinstock, Matthew, Bisharat, Lina, Morin, Adam, Mahoney, Kathleen M., Ebert, Benjamin, Stone, Richard, Kufe, Donald, Freeman, Gordon J., Rosenblatt, Jacalyn, Avigan, David

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VISTA: A Mediator of Quiescence and a Promising Target in Cancer Immunotherapy von Yuan, Long, Tatineni, Jahnavi, Mahoney, Kathleen M., Freeman, Gordon J.

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Phase 1 first-in-human study of dalutrafusp alfa, an anti–CD73-TGF-β-trap bifunctional antibody, in patients with advanced solid tumors von Tolcher, Anthony W, Gordon, Michael, Mahoney, Kathleen M, Seto, Anna, Zavodovskaya, Marianna, Hsueh, Chia-Hsiang, Zhai, Shuyan, Tarnowski, Thomas, Jürgensmeier, Juliane M, Stinson, Susanna, Othman, Ahmed A, Chen, Tianling, Strauss, James

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Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlights von Noelle, Randolph J., Lines, J. Louise, Lewis, Lionel D., Martell, Robert E., Guillaudeux, Thierry, Lee, Sam W., Mahoney, Kathleen M., Vesely, Matthew D., Boyd-Kirkup, Jerome, Nambiar, Dhanya K., Scott, Andrew M.

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Prognostic and predictive markers for the new immunotherapies von Mahoney, Kathleen M, Atkins, Michael B

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Progressive immune dysfunction with advancing disease stage in renal cell carcinoma von Braun, David A., Street, Kelly, Burke, Kelly P., Cookmeyer, David L., Denize, Thomas, Pedersen, Christina B., Gohil, Satyen H., Schindler, Nicholas, Pomerance, Lucas, Hirsch, Laure, Bakouny, Ziad, Hou, Yue, Forman, Juliet, Huang, Teddy, Li, Shuqiang, Cui, Ang, Keskin, Derin B., Steinharter, John, Bouchard, Gabrielle, Sun, Maxine, Pimenta, Erica M., Xu, Wenxin, Mahoney, Kathleen M., McGregor, Bradley A., Hirsch, Michelle S., Chang, Steven L., Livak, Kenneth J., McDermott, David F., Shukla, Sachet A., Olsen, Lars R., Signoretti, Sabina, Sharpe, Arlene H., Irizarry, Rafael A., Choueiri, Toni K., Wu, Catherine J.

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Acidity changes immunology: a new VISTA pathway von Mahoney, Kathleen M., Freeman, Gordon J.

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Soluble PD-L1 as a Biomarker in Malignant Melanoma Treated with Checkpoint Blockade von Zhou, Jun, Mahoney, Kathleen M, Giobbie-Hurder, Anita, Zhao, Fengmin, Lee, Sandra, Liao, Xiaoyun, Rodig, Scott, Li, Jingjing, Wu, Xinqi, Butterfield, Lisa H, Piesche, Matthias, Manos, Michael P, Eastman, Lauren M, Dranoff, Glenn, Freeman, Gordon J, Hodi, F Stephen

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A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression von Mahoney, Kathleen M., Shukla, Sachet A., Patsoukis, Nikolaos, Chaudhri, Apoorvi, Browne, Edward P., Arazi, Arnon, Eisenhaure, Thomas M., Pendergraft, William F., Hua, Ping, Pham, Hung C., Bu, Xia, Zhu, Baogong, Hacohen, Nir, Fritsch, Edward F., Boussiotis, Vassiliki A., Wu, Catherine J., Freeman, Gordon J.

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KIR3DL3 Is an Inhibitory Receptor for HHLA2 that Mediates an Alternative Immunoinhibitory for Pathway to PD1 von Bhatt, Rupal S., Berjis, Abdulla, Konge, Julie C., Mahoney, Kathleen M., Klee, Alyssa N., Freeman, Samuel S., Chen, Chun-Hau, Jegede, Opeyemi A., Catalano, Paul J., Pignon, Jean-Christophe, Sticco-Ivins, Maura, Zhu, Baogong, Hua, Ping, Soden, Jo, Zhu, Jie, McDermott, David F., Arulanandam, Antonio R., Signoretti, Sabina, Freeman, Gordon J.

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Adjuvant trastuzumab with chemotherapy is effective in women with small, node‐negative, HER2‐positive breast cancer von McArthur, Heather L., Mahoney, Kathleen M., Morris, Patrick G., Patil, Sujata, Jacks, Lindsay M., Howard, Jane, Norton, Larry, Hudis, Clifford A.

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Monitoring PD-1 Phosphorylation to Evaluate PD-1 Signaling during Antitumor Immune Responses von Bu, Xia, Juneja, Vikram R., Reynolds, Carol G., Mahoney, Kathleen M., Bu, Melissa T., McGuire, Kathleen A., Maleri, Seth, Hua, Ping, Zhu, Baogong, Klein, Sarah R., Greenfield, Edward A., Armand, Philippe, Ritz, Jerome, Sharpe, Arlene H., Freeman, Gordon J.

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