Mechanistic insights into GPCR–G protein interactions von Mahoney, Jacob P, Sunahara, Roger K

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Allosteric coupling from G protein to the agonist-binding pocket in GPCRs von DeVree, Brian T., Mahoney, Jacob P., Vélez-Ruiz, Gisselle A., Rasmussen, Soren G. F., Kuszak, Adam J., Edwald, Elin, Fung, Juan-Jose, Manglik, Aashish, Masureel, Matthieu, Du, Yang, Matt, Rachel A., Pardon, Els, Steyaert, Jan, Kobilka, Brian K., Sunahara, Roger K.

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Conformational biosensors reveal GPCR signalling from endosomes von Irannejad, Roshanak, Tomshine, Jin C., Tomshine, Jon R., Chevalier, Michael, Mahoney, Jacob P., Steyaert, Jan, Rasmussen, Søren G. F., Sunahara, Roger K., El-Samad, Hana, Huang, Bo, von Zastrow, Mark

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GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling von Thomsen, Alex R.B., Plouffe, Bianca, Cahill, Thomas J., Shukla, Arun K., Tarrasch, Jeffrey T., Dosey, Annie M., Kahsai, Alem W., Strachan, Ryan T., Pani, Biswaranjan, Mahoney, Jacob P., Huang, Liyin, Breton, Billy, Heydenreich, Franziska M., Sunahara, Roger K., Skiniotis, Georgios, Bouvier, Michel, Lefkowitz, Robert J.

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Structural insights into binding specificity, efficacy and bias of a β 2 AR partial agonist von Masureel, Matthieu, Zou, Yaozhong, Picard, Louis-Philippe, van der Westhuizen, Emma, Mahoney, Jacob P, Rodrigues, João P G L M, Mildorf, Thomas J, Dror, Ron O, Shaw, David E, Bouvier, Michel, Pardon, Els, Steyaert, Jan, Sunahara, Roger K, Weis, William I, Zhang, Cheng, Kobilka, Brian K

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Structure of an endosomal signaling GPCR–G protein–β-arrestin megacomplex von Nguyen, Anthony H., Thomsen, Alex R. B., Cahill, Thomas J., Huang, Rick, Huang, Li-Yin, Marcink, Tara, Clarke, Oliver B., Heissel, Søren, Masoudi, Ali, Ben-Hail, Danya, Samaan, Fadi, Dandey, Venkata P., Tan, Yong Zi, Hong, Chuan, Mahoney, Jacob P., Triest, Sarah, Little, John, Chen, Xin, Sunahara, Roger, Steyaert, Jan, Molina, Henrik, Yu, Zhiheng, des Georges, Amedee, Lefkowitz, Robert J.

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Reconstitution of purified membrane protein dimers in lipid nanodiscs with defined stoichiometry and orientation using a split GFP tether von Bruguera, Elise S., Mahoney, Jacob P., Weis, William I.

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Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist von Masureel, Matthieu, Zou, Yaozhong, Picard, Louis-Philippe, van der Westhuizen, Emma, Mahoney, Jacob P., Rodrigues, João P. G. L. M., Mildorf, Thomas J., Dror, Ron O., Shaw, David E., Bouvier, Michel, Pardon, Els, Steyaert, Jan, Sunahara, Roger K., Weis, William I., Zhang, Cheng, Kobilka, Brian K.

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PI(4,5)P 2 -stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt-β-catenin signaling von Mahoney, Jacob P, Bruguera, Elise S, Vasishtha, Mansi, Killingsworth, Lauren B, Kyaw, Saw, Weis, William I

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Measuring ligand efficacy at the mu-opioid receptor using a conformational biosensor von Livingston, Kathryn E, Mahoney, Jacob P, Manglik, Aashish, Sunahara, Roger K, Traynor, John R

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PI(4,5)P2-stimulated positive feedback drives the recruitment of Dishevelled to Frizzled in Wnt–β-catenin signaling von Mahoney, Jacob P, Bruguera, Elise S, Mansi Vasishtha, Killingsworth, Lauren B, Saw Kyaw, Weis, William I

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Publisher Correction: Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist von Masureel, Matthieu, Zou, Yaozhong, Picard, Louis-Philippe, van der Westhuizen, Emma, Mahoney, Jacob P., Rodrigues, João P. G. L. M., Mildorf, Thomas J., Dror, Ron O., Shaw, David E., Bouvier, Michel, Pardon, Els, Steyaert, Jan, Sunahara, Roger K., Weis, William I., Zhang, Cheng, Kobilka, Brian K.

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The co-receptor Tetraspanin12 directly captures Norrin to promote ligand-specific β-catenin signaling von Bruguera, Elise S, Mahoney, Jacob P, Weis, William I

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Negative design at the carboxy‐terminal beta‐edge of truncated hemolysin A von Mahoney, Jacob, Weaver, Todd

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Efficacy at the Mu Opioid Receptor: Insights from Orthosteric and Allosteric Ligands von Livingston, Kathryn E, Mahoney, Jacob, Manglik, Aashish, Kobilka, Brian, Sunahara, Roger, Traynor, John R

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Electron Microscopic Visualization of Protein Assemblies on Flattened DNA Origami von Mallik, Leena, Dhakal, Soma, Nichols, Joseph, Mahoney, Jacob, Dosey, Anne M, Jiang, Shuoxing, Sunahara, Roger K, Skiniotis, Georgios, Walter, Nils G

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Structure of an endosomal signaling GPCR-G protein-[beta]-arrestin megacomplex von Nguyen, Anthony H, Thomsen, Alex R. B, Cahill, Thomas J., III, Huang, Rick, Huang, Li-Yin, Marcink, Tara, Clarke, Oliver B, Heissel, Soren, Masoudi, Ali, Ben-Hail, Danya, Samaan, Fadi, Dandey, Venkata P, Tan, Yong Zi, Hong, Chuang, Mahoney, Jacob P, Triest, Sarah, Little, John, IV, Chen, Xin, Sunahara, Roger, Steyaert, Jan, Molina, Henrik, Yu, Zhiheng, des Georges, Amedee, Lefkowitz, Robert J

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Structure of an Endosomal Signaling GPCR–G Protein–β-arrestin Mega-Complex von Nguyen, Anthony H., Thomsen, Alex R. B., Cahill, Thomas J., Huang, Rick, Huang, Li-Yin, Marcink, Tara, Clarke, Oliver B., Heissel, Søren, Masoudi, Ali, Ben-Hail, Danya, Samaan, Fadi, Dandey, Venkata P., Tan, Yong Zi, Hong, Chuan, Mahoney, Jacob P., Triest, Sarah, Little, John, Chen, Xin, Sunahara, Roger, Steyaert, Jan, Molina, Henrik, Yu, Zhiheng, des Georges, Amedee, Lefkowitz, Robert J.

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Impact of PI(3,4,5)P3-Mediated Beta-Arrestin-1 Recruitment on Structure of Asymmetric Lipid Bilayers von Nzulumike, Achebe N.O., Mathiasen, Signe, Mahoney, Jacob P., Cárdenas Gómez, Marité, Stamou, Dimitrios G., Mortensen, Kell

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Structural Basis for Allosteric Enhancement of Agonist Affinity by G Proteins von Mahoney, Jacob, DeVree, Brian, Velez‐Ruiz, Gisselle, Rasmussen, Soren, Kuszak, Adam, Pardon, Els, Steyaert, Jan, Kobilka, Brian, Sunahara, Roger

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