Mutation patterns identify adult patients with de novo acute myeloid leukemia aged 60 years or older who respond favorably to standard chemotherapy: an analysis of Alliance studies von Eisfeld, Ann-Kathrin, Kohlschmidt, Jessica, Mrózek, Krzysztof, Blachly, James S., Walker, Christopher J., Nicolet, Deedra, Orwick, Shelley, Maharry, Sophia E., Carroll, Andrew J., Stone, Richard M., de la Chapelle, Albert, Wang, Eunice S., Kolitz, Jonathan E., Powell, Bayard L., Byrd, John C., Bloomfield, Clara D.

Volltext

Poor Survival and Differential Impact of Genetic Features of Black Patients with Acute Myeloid Leukemia von Bhatnagar, Bhavana, Kohlschmidt, Jessica, Mrozek, Krzysztof, Zhao, Qiuhong, Fisher, James L., Nicolet, Deedra, Walker, Christopher J., Mims, Alice S., Oakes, Christopher, Giacopelli, Brian, Orwick, Shelley, Boateng, Isaiah, Blachly, James S., Maharry, Sophia E., Carroll, Andrew J., Powell, Bayard L., Kolitz, Jonathan E., Stone, Richard M., Byrd, John C., Paskett, Electra D., de la Chapelle, Albert, Garzon, Ramiro, Eisfeld, Ann-Kathrin

Volltext

NF1 mutations are recurrent in adult acute myeloid leukemia and confer poor outcome von Eisfeld, Ann-Kathrin, Kohlschmidt, Jessica, Mrózek, Krzysztof, Mims, Alice, Walker, Christopher J., Blachly, James S., Nicolet, Deedra, Orwick, Shelley, Maharry, Sophia E., Carroll, Andrew J., Powell, Bayard L., Kolitz, Jonathan E., Wang, Eunice S., Stone, Richard M., de la Chapelle, Albert, Byrd, John C., Bloomfield, Clara D.

Volltext

The Role of NRG1 in the Predisposition to Papillary Thyroid Carcinoma von He, Huiling, Li, Wei, Liyanarachchi, Sandya, Wang, Yanqiang, Yu, Lianbo, Genutis, Luke K, Maharry, Sophia, Phay, John E, Shen, Rulong, Brock, Pamela, de la Chapelle, Albert

Volltext

MicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies von Lankenau, Malori A, Patel, Ravi, Liyanarachchi, Sandya, Maharry, Sophia E, Hoag, Kevin W, Duggan, Megan, Walker, Christopher J, Markowitz, Joseph, Carson, 3rd, William E, Eisfeld, Ann-Kathrin, de la Chapelle, Albert

Volltext

Genetic Characterization and Prognostic Relevance of Acquired Uniparental Disomies in Cytogenetically Normal Acute Myeloid Leukemia von Walker, Christopher J, Kohlschmidt, Jessica, Eisfeld, Ann-Kathrin, Mrózek, Krzysztof, Liyanarachchi, Sandya, Song, Chi, Nicolet, Deedra, Blachly, James S, Bill, Marius, Papaioannou, Dimitrios, Oakes, Christopher C, Giacopelli, Brian, Genutis, Luke K, Maharry, Sophia E, Orwick, Shelley, Archer, Kellie J, Powell, Bayard L, Kolitz, Jonathan E, Uy, Geoffrey L, Wang, Eunice S, Carroll, Andrew J, Stone, Richard M, Byrd, John C, de la Chapelle, Albert, Bloomfield, Clara D

Volltext

Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia von Maharry, Sophia E, Walker, Christopher J, Liyanarachchi, Sandya, Mehta, Sujay, Patel, Mitra, Bainazar, Maryam A, Huang, Xiaomeng, Lankenau, Malori A, Hoag, Kevin W, Ranganathan, Parvathi, Garzon, Ramiro, Blachly, James S, Guttridge, Denis C, Bloomfield, Clara D, de la Chapelle, Albert, Eisfeld, Ann-Kathrin

Volltext

Abstract 1117: Dissection of the major hematopoietic quantitative trait locus in chromosome 6q23.3 identifies miR-3662 as a player in hematopoiesis and AML von Maharry, Sophia E., Walker, Christopher J., Liyanarachchi, Sandya, Mehta, Sujay, Blachly, James S., Guttridge, Denis C., Bloomfield, Clara D., de la Chapelle, Albert, Eisfeld, Ann-Kathrin

Volltext

Abstract 1753: Genomic and transcriptomic characterization of congenital trisomy reveal possible role for RB1 and MET von Bainazar, Maryam A., Maharry, Sophia E., Walker, Christopher J., Genutis, Luke K., Chapelle, Albert de la, Eisfeld, Ann-Kathrin

Volltext

The 2017 European Leukemianet Genetic Risk Classification Performs Poorly in Older Patients with Acute Myeloid Leukemia (AML) and Should be Refined to Identify Patients Requiring A... von Eisfeld, Ann-Kathrin, Kohlschmidt, Jessica, Mrózek, Krzysztof, Nicolet, Deedra, Mims, Alice S., Papaioannou, Dimitrios, Walker, Christopher J., Blachly, James S., Maharry, Sophia E., Carroll, Andrew J., Stone, Richard M., Powell, Bayard L, de la Chapelle, Albert, Wang, Eunice S., Kolitz, Jonathan E., Byrd, John C., Bloomfield, Clara D.

Volltext

Identification of NRAS isoform 2 overexpression as a mechanism facilitating BRAF inhibitor resistance in malignant melanoma von Duggan, Megan C., Stiff, Andrew R., Bainazar, Maryam, Regan, Kelly, Salavaggione, Gonzalo N. Olaverria, Maharry, Sophia, Blachly, James S., Krischak, Madison, Walker, Christopher J., Latchana, Nicholas, Tridandapani, Susheela, de la Chapelle, Albert, Eisfeld, Ann-Kathrin, Carson, William E.

Volltext

Micro RNA-3662 Located within the Major Hematopoietic Differentiation Quantitative Trait Locus on Chromosome 6q23 Acts As a Tumor Suppressor By Direct Targeting of the NF-ĸB Transc... von Maharry, Sophia E., Mehta, Sujay, Liyanarachchi, Sandya, Walker, Christopher J., Bloomfield, Clara D., de la Chapelle, Albert, Eisfeld, Ann-Kathrin

Volltext

Abstract 5235: Identification of microRNA -3662 as a novel tumor suppressor miR von Maharry, Sophia, Mehta, Sujay, Liyanarachchi, Sandya, Marcucci, Guido, Bloomfield, Clara D., Chapelle, Albert de la, Eisfeld, Ann-Kathrin

Volltext

MicroRNA-3151 inactivates TP53 inBRAF-mutated human malignancies von Lankenau, Malori A., Patel, Ravi, Liyanarachchi, Sandya, Maharry, Sophia E., Hoag, Kevin W., Duggan, Megan, Walker, Christopher J., Markowitz, Joseph, Carson, William E., Eisfeld, Ann-Kathrin, de la Chapelle, Albert

Volltext

Dissection of the major hematopoietic quantitative trait locus in chromosome 6q23.3 identifies miR-3662 as a novel player in hematopoiesis and acute myeloid leukemia von Maharry, Sophia E., Walker, Christopher J., Liyanarachchi, Sandya, Mehta, Sujay, Patel, Mitra, Bainazar, Maryam A., Huang, Xiaomeng, Lankenau, Malori A., Hoag, Kevin W., Ranganathan, Parvathi, Garzon, Ramiro, Blachly, James S., Guttridge, Denis C., Bloomfield, Clara D., de la Chapelle, Albert, Eisfeld, Ann-Kathrin

Volltext