HMDB 5.0: the Human Metabolome Database for 2022 von Wishart, David S, Guo, AnChi, Oler, Eponine, Wang, Fei, Anjum, Afia, Peters, Harrison, Dizon, Raynard, Sayeeda, Zinat, Tian, Siyang, Lee, Brian L, Berjanskii, Mark, Mah, Robert, Yamamoto, Mai, Jovel, Juan, Torres-Calzada, Claudia, Hiebert-Giesbrecht, Mickel, Lui, Vicki W, Varshavi, Dorna, Varshavi, Dorsa, Allen, Dana, Arndt, David, Khetarpal, Nitya, Sivakumaran, Aadhavya, Harford, Karxena, Sanford, Selena, Yee, Kristen, Cao, Xuan, Budinski, Zachary, Liigand, Jaanus, Zhang, Lun, Zheng, Jiamin, Mandal, Rupasri, Karu, Naama, Dambrova, Maija, Schiöth, Helgi B, Greiner, Russell, Gautam, Vasuk

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Drug discovery considerations in the development of covalent inhibitors von Mah, Robert, Thomas, Jason R, Shafer, Cynthia M

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NP-MRD: the Natural Products Magnetic Resonance Database von Wishart, David S, Sayeeda, Zinat, Budinski, Zachary, Guo, AnChi, Lee, Brian L, Berjanskii, Mark, Rout, Manoj, Peters, Harrison, Dizon, Raynard, Mah, Robert, Torres-Calzada, Claudia, Hiebert-Giesbrecht, Mickel, Varshavi, Dorna, Varshavi, Dorsa, Oler, Eponine, Allen, Dana, Cao, Xuan, Gautam, Vasuk, Maras, Andrew, Poynton, Ella F, Tavangar, Pegah, Yang, Vera, van Santen, Jeffrey A, Ghosh, Rajarshi, Sarma, Saurav, Knutson, Eleanor, Sullivan, Victoria, Jystad, Amy M, Renslow, Ryan, Sumner, Lloyd W, Linington, Roger G, Cort, John R

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Discovery of a novel class of highly potent inhibitors of the p53–MDM2 interaction by structure-based design starting from a conformational argument von Furet, Pascal, Masuya, Keiichi, Kallen, Joerg, Stachyra-Valat, Thérèse, Ruetz, Stephan, Guagnano, Vito, Holzer, Philipp, Mah, Robert, Stutz, Stefan, Vaupel, Andrea, Chène, Patrick, Jeay, Sébastien, Schlapbach, Achim

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2‑Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4 von Knoepfel, Thomas, Furet, Pascal, Mah, Robert, Buschmann, Nicole, Leblanc, Catherine, Ripoche, Sebastien, Graus-Porta, Diana, Wartmann, Markus, Galuba, Inga, Fairhurst, Robin A

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Structural States of Hdm2 and HdmX: X‐ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes von Kallen, Joerg, Izaac, Aude, Chau, Suzanne, Wirth, Emmanuelle, Schoepfer, Joseph, Mah, Robert, Schlapbach, Achim, Stutz, Stefan, Vaupel, Andrea, Guagnano, Vito, Masuya, Keiichi, Stachyra, Therese‐Marie, Salem, Bahaa, Chene, Patrick, Gessier, Francois, Holzer, Philipp, Furet, Pascal

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Structure-based design of aliskiren, a novel orally effective renin inhibitor von Wood, Jeanette M, Maibaum, Jürgen, Rahuel, Joseph, Grütter, Markus G, Cohen, Nissim-Claude, Rasetti, Vittorio, Rüger, Heinrich, Göschke, Richard, Stutz, Stefan, Fuhrer, Walter, Schilling, Walter, Rigollier, Pascal, Yamaguchi, Yasuchika, Cumin, Frederic, Baum, Hans-Peter, Schnell, Christian R, Herold, Peter, Mah, Robert, Jensen, Chris, O’Brien, Eoin, Stanton, Alice, Bedigian, Martin P

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Abstract 1239: NVP-HDM201: Biochemical and biophysical profile of a novel highly potent and selective PPI inhibitor of p53-Mdm2 von Stachyra-Valat, Thérèse, Baysang, Frédéric, D’Alessandro, Anne-Cécile, Dirk, Erdmann, Furet, Pascal, Guagnano, Vito, Kallen, Joerg, Leder, Lukas, Mah, Robert, Masuya, Keiichi, Stutz, Stefan, Vaupel, Andrea, Hofmann, Francesco, Chène, Patrick, Jeay, Sébastien, Holzer, Philipp

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Anaerobic bacteria from hypersaline environments von OLLIVIER, B, CAUMETTE, P, GARCIA, J.-L, MAH, R. A

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Discovery of Roblitinib (FGF401) as a Reversible-Covalent Inhibitor of the Kinase Activity of Fibroblast Growth Factor Receptor 4 von Fairhurst, Robin A, Knoepfel, Thomas, Buschmann, Nicole, Leblanc, Catherine, Mah, Robert, Todorov, Milen, Nimsgern, Pierre, Ripoche, Sebastien, Niklaus, Michel, Warin, Nicolas, Luu, Van Huy, Madoerin, Mario, Wirth, Jasmin, Graus-Porta, Diana, Weiss, Andreas, Kiffe, Michael, Wartmann, Markus, Kinyamu-Akunda, Jacqueline, Sterker, Dario, Stamm, Christelle, Adler, Flavia, Buhles, Alexandra, Schadt, Heiko, Couttet, Philippe, Blank, Jutta, Galuba, Inga, Trappe, Jörg, Voshol, Johannes, Ostermann, Nils, Zou, Chao, Berghausen, Jörg, Del Rio Espinola, Alberto, Jahnke, Wolfgang, Furet, Pascal

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FGF401, A First-In-Class Highly Selective and Potent FGFR4 Inhibitor for the Treatment of FGF19-Driven Hepatocellular Cancer von Weiss, Andreas, Adler, Flavia, Buhles, Alexandra, Stamm, Christelle, Fairhurst, Robin A, Kiffe, Michael, Sterker, Dario, Centeleghe, Mario, Wartmann, Markus, Kinyamu-Akunda, Jacqueline, Schadt, Heiko S, Couttet, Philippe, Wolf, Armin, Wang, Youzhen, Barzaghi-Rinaudo, Patrizia, Murakami, Masato, Kauffmann, Audrey, Knoepfel, Thomas, Buschmann, Nicole, Leblanc, Catherine, Mah, Robert, Furet, Pascal, Blank, Jutta, Hofmann, Francesco, Sellers, William R, Graus Porta, Diana

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THE FUTURE ROLE OF INTELLIGENT PROBES IN DETECTING AND MANAGING PROSTATE CANCER von KOMMU, SASHI S., ANDREWS, RUSSELL J., MAH, ROBERT W.

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ChemFOnt: the chemical functional ontology resource von Wishart, David S, Girod, Sagan, Peters, Harrison, Oler, Eponine, Jovel, Juan, Budinski, Zachary, Milford, Ralph, Lui, Vicki W, Sayeeda, Zinat, Mah, Robert, Wei, William, Badran, Hasan, Lo, Elvis, Yamamoto, Mai, Djoumbou-Feunang, Yannick, Karu, Naama, Gautam, Vasuk

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In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor von Vaupel, Andrea, Holzer, Philipp, Ferretti, Stephane, Guagnano, Vito, Kallen, Joerg, Mah, Robert, Masuya, Keiichi, Ruetz, Stephan, Rynn, Caroline, Schlapbach, Achim, Stachyra, Thérèse, Stutz, Stefan, Todorov, Milen, Jeay, Sébastien, Furet, Pascal

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Real‐time multiple microsensor tissue recognition and its potential application in the management of prostate cancer von KOMMU, SASHI S., ANDREWS, RUSSELL J., MAH, ROBERT W.

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Diagnosis of Fault Modes Masked by Control Loops with an Application to Autonomous Hovercraft Systems von Ioannis A. Raptis, Rodney Martin, Robert Mah, Nikunj Oza, Dimitri Mavris, Sehwan Oh, Kilsoo Kim, Young-Ki Lee, Christopher Sconyers, George J. Vachtsevanos

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Discovery of a novel tricyclic 4H-thiazolo[5′,4′:4,5]pyrano[2,3-c]pyridine-2-amino scaffold and its application in a PI3Kα inhibitor with high PI3K isoform selectivity and potent c... von Gerspacher, Marc, Fairhurst, Robin A., Mah, Robert, Roehn-Carnemolla, Esther, Furet, Pascal, Fritsch, Christine, Guthy, Daniel A.

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Fault Tolerance of Relative Navigation Sensing in Docking Approach of Spacecraft von Gorinevsky, D., Hoffmann, G.M., Shmakova, M., Mah, R.W., Cryan, S., Mitchell, J.D.

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Correction to “2-Formylpyridyl Ureas as Highly Selective Reversible-Covalent Inhibitors of Fibroblast Growth Factor Receptor 4” von Knoepfel, Thomas, Furet, Pascal, Mah, Robert, Buschmann, Nicole, Leblanc, Catherine, Ripoche, Sebastien, Graus-Porta, Diana, Wartmann, Markus, Galuba, Inga, Fairhurst, Robin A

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Front Cover: Structural States of Hdm2 and HdmX: X‐ray Elucidation of Adaptations and Binding Interactions for Different Chemical Compound Classes (ChemMedChem 14/2019) von Kallen, Joerg, Izaac, Aude, Chau, Suzanne, Wirth, Emmanuelle, Schoepfer, Joseph, Mah, Robert, Schlapbach, Achim, Stutz, Stefan, Vaupel, Andrea, Guagnano, Vito, Masuya, Keiichi, Stachyra, Therese‐Marie, Salem, Bahaa, Chene, Patrick, Gessier, Francois, Holzer, Philipp, Furet, Pascal

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