Characterizing Mutational Signatures in Human Cancer Cell Lines Reveals Episodic APOBEC Mutagenesis von Petljak, Mia, Alexandrov, Ludmil B., Brammeld, Jonathan S., Price, Stacey, Wedge, David C., Grossmann, Sebastian, Dawson, Kevin J., Ju, Young Seok, Iorio, Francesco, Tubio, Jose M.C., Koh, Ching Chiek, Georgakopoulos-Soares, Ilias, Rodríguez–Martín, Bernardo, Otlu, Burçak, O’Meara, Sarah, Butler, Adam P., Menzies, Andrew, Bhosle, Shriram G., Raine, Keiran, Jones, David R., Teague, Jon W., Beal, Kathryn, Latimer, Calli, O’Neill, Laura, Zamora, Jorge, Anderson, Elizabeth, Patel, Nikita, Maddison, Mark, Ng, Bee Ling, Graham, Jennifer, Garnett, Mathew J., McDermott, Ultan, Nik-Zainal, Serena, Campbell, Peter J., Stratton, Michael R.

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Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma von Behjati, Sam, Tarpey, Patrick S., Haase, Kerstin, Ye, Hongtao, Young, Matthew D., Alexandrov, Ludmil B., Farndon, Sarah J., Collord, Grace, Wedge, David C., Martincorena, Inigo, Cooke, Susanna L., Davies, Helen, Mifsud, William, Lidgren, Mathias, Martin, Sancha, Latimer, Calli, Maddison, Mark, Butler, Adam P., Teague, Jon W., Pillay, Nischalan, Shlien, Adam, McDermott, Ultan, Futreal, P. Andrew, Baumhoer, Daniel, Zaikova, Olga, Bjerkehagen, Bodil, Myklebost, Ola, Amary, M. Fernanda, Tirabosco, Roberto, Van Loo, Peter, Stratton, Michael R., Flanagan, Adrienne M., Campbell, Peter J.

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Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes von Teh, Bin Tean, Stratton, Michael R, Futreal, P. Andrew, Dalgliesh, Gillian L, Furge, Kyle, Greenman, Chris, Chen, Lina, Bignell, Graham, Butler, Adam, Davies, Helen, Edkins, Sarah, Hardy, Claire, Latimer, Calli, Teague, Jon, Andrews, Jenny, Barthorpe, Syd, Beare, Dave, Buck, Gemma, Campbell, Peter J, Forbes, Simon, Jia, Mingming, Jones, David, Knott, Henry, Kok, Chai Yin, Lau, King Wai, Leroy, Catherine, Lin, Meng-Lay, McBride, David J, Maddison, Mark, Maguire, Simon, McLay, Kirsten, Menzies, Andrew, Mironenko, Tatiana, Mulderrig, Lee, Mudie, Laura, O'Meara, Sarah, Pleasance, Erin, Rajasingham, Arjunan, Shepherd, Rebecca, Smith, Raffaella, Stebbings, Lucy, Stephens, Philip, Tang, Gurpreet, Tarpey, Patrick S, Turrell, Kelly, Dykema, Karl J, Khoo, Sok Kean, Petillo, David, Wondergem, Bill, Anema, John, Kahnoski, Richard J

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Frequent mutation of the major cartilage collagen gene COL2A1 in chondrosarcoma von Tarpey, Patrick S, Behjati, Sam, Cooke, Susanna L, Van Loo, Peter, Wedge, David C, Pillay, Nischalan, Marshall, John, O'Meara, Sarah, Davies, Helen, Nik-Zainal, Serena, Beare, David, Butler, Adam, Gamble, John, Hardy, Claire, Hinton, Jonathon, Jia, Ming Ming, Jayakumar, Alagu, Jones, David, Latimer, Calli, Maddison, Mark, Martin, Sancha, McLaren, Stuart, Menzies, Andrew, Mudie, Laura, Raine, Keiran, Teague, Jon W, Tubio, Jose M C, Halai, Dina, Tirabosco, Roberto, Amary, Fernanda, Campbell, Peter J, Stratton, Michael R, Flanagan, Adrienne M, Futreal, P Andrew

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Genome sequence of a proteolytic (Group I) Clostridium botulinum strain Hall A and comparative analysis of the clostridial genomes von Sebaihia, Mohammed, Peck, Michael W, Minton, Nigel P, Thomson, Nicholas R, Holden, Matthew T G, Mitchell, Wilfrid J, Carter, Andrew T, Bentley, Stephen D, Mason, David R, Crossman, Lisa, Paul, Catherine J, Ivens, Alasdair, Wells-Bennik, Marjon H J, Davis, Ian J, Cerdeño-Tárraga, Ana M, Churcher, Carol, Quail, Michael A, Chillingworth, Tracey, Feltwell, Theresa, Fraser, Audrey, Goodhead, Ian, Hance, Zahra, Jagels, Kay, Larke, Natasha, Maddison, Mark, Moule, Sharon, Mungall, Karen, Norbertczak, Halina, Rabbinowitsch, Ester, Sanders, Mandy, Simmonds, Mark, White, Brian, Whithead, Sally, Parkhill, Julian

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Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18 von Bentley, Stephen D, Vernikos, George S, Snyder, Lori A S, Churcher, Carol, Arrowsmith, Claire, Chillingworth, Tracey, Cronin, Ann, Davis, Paul H, Holroyd, Nancy E, Jagels, Kay, Maddison, Mark, Moule, Sharon, Rabbinowitsch, Ester, Sharp, Sarah, Unwin, Louise, Whitehead, Sally, Quail, Michael A, Achtman, Mark, Barrell, Bart, Saunders, Nigel J, Parkhill, Julian

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The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081 von Thomson, Nicholas R, Howard, Sarah, Wren, Brendan W, Holden, Matthew T G, Crossman, Lisa, Challis, Gregory L, Churcher, Carol, Mungall, Karen, Brooks, Karen, Chillingworth, Tracey, Feltwell, Theresa, Abdellah, Zahra, Hauser, Heidi, Jagels, Kay, Maddison, Mark, Moule, Sharon, Sanders, Mandy, Whitehead, Sally, Quail, Michael A, Dougan, Gordon, Parkhill, Julian, Prentice, Michael B

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Genome sequencing of normal cells reveals developmental lineages and mutational processes von Behjati, Sam, Huch, Meritxell, van Boxtel, Ruben, Karthaus, Wouter, Wedge, David C., Tamuri, Asif U., Martincorena, Iñigo, Petljak, Mia, Alexandrov, Ludmil B., Gundem, Gunes, Tarpey, Patrick S., Roerink, Sophie, Blokker, Joyce, Maddison, Mark, Mudie, Laura, Robinson, Ben, Nik-Zainal, Serena, Campbell, Peter, Goldman, Nick, van de Wetering, Marc, Cuppen, Edwin, Clevers, Hans, Stratton, Michael R.

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Gold and Brønsted Acid Catalyzed Spirocyclization of 2- and 3‑Indolyl-Tethered 1,4-Enyne Acetates to Spiro[4,n]alkyl[b]indoles von Chen, Xiaoyu, Baratay, Corentin Antoine, Mark, Maddison Elizabeth, Xu, Xinfang, Hong Chan, Philip Wai

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Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue von Cooper, Colin S, Eeles, Rosalind, Wedge, David C, Van Loo, Peter, Gundem, Gunes, Alexandrov, Ludmil B, Kremeyer, Barbara, Butler, Adam, Lynch, Andrew G, Camacho, Niedzica, Massie, Charlie E, Kay, Jonathan, Luxton, Hayley J, Edwards, Sandra, Kote-Jarai, Zsofia, Dennis, Nening, Merson, Sue, Leongamornlert, Daniel, Zamora, Jorge, Corbishley, Cathy, Thomas, Sarah, Nik-Zainal, Serena, Ramakrishna, Manasa, O'Meara, Sarah, Matthews, Lucy, Clark, Jeremy, Hurst, Rachel, Mithen, Richard, Bristow, Robert G, Boutros, Paul C, Fraser, Michael, Cooke, Susanna, Raine, Keiran, Jones, David, Menzies, Andrew, Stebbings, Lucy, Hinton, Jon, Teague, Jon, McLaren, Stuart, Mudie, Laura, Hardy, Claire, Anderson, Elizabeth, Joseph, Olivia, Goody, Victoria, Robinson, Ben, Maddison, Mark, Gamble, Stephen, Greenman, Christopher, Berney, Dan, Hazell, Steven, Livni, Naomi, Fisher, Cyril, Ogden, Christopher, Kumar, Pardeep, Thompson, Alan, Woodhouse, Christopher, Nicol, David, Mayer, Erik, Dudderidge, Tim, Shah, Nimish C, Gnanapragasam, Vincent, Voet, Thierry, Campbell, Peter, Futreal, Andrew, Easton, Douglas, Warren, Anne Y, Foster, Christopher S, Stratton, Michael R, Whitaker, Hayley C, McDermott, Ultan, Brewer, Daniel S, Neal, David E

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Mutational Processes Molding the Genomes of 21 Breast Cancers von Nik-Zainal, Serena, Alexandrov, Ludmil B., Wedge, David C., Van Loo, Peter, Greenman, Christopher D., Raine, Keiran, Jones, David, Hinton, Jonathan, Marshall, John, Stebbings, Lucy A., Menzies, Andrew, Martin, Sancha, Leung, Kenric, Chen, Lina, Leroy, Catherine, Ramakrishna, Manasa, Rance, Richard, Lau, King Wai, Mudie, Laura J., Varela, Ignacio, McBride, David J., Bignell, Graham R., Cooke, Susanna L., Shlien, Adam, Gamble, John, Whitmore, Ian, Maddison, Mark, Tarpey, Patrick S., Davies, Helen R., Papaemmanuil, Elli, Stephens, Philip J., McLaren, Stuart, Butler, Adam P., Teague, Jon W., Jönsson, Göran, Garber, Judy E., Silver, Daniel, Miron, Penelope, Fatima, Aquila, Boyault, Sandrine, Langerød, Anita, Tutt, Andrew, Martens, John W.M., Aparicio, Samuel A.J.R., Borg, Åke, Salomon, Anne Vincent, Thomas, Gilles, Børresen-Dale, Anne-Lise, Richardson, Andrea L., Neuberger, Michael S., Futreal, P. Andrew, Campbell, Peter J., Stratton, Michael R.

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C. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiency von Meier, Bettina, Cooke, Susanna L, Weiss, Joerg, Bailly, Aymeric P, Alexandrov, Ludmil B, Marshall, John, Raine, Keiran, Maddison, Mark, Anderson, Elizabeth, Stratton, Michael R, Gartner, Anton, Campbell, Peter J

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Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes von Tubio, Jose M. C.

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Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia von Li, Yilong, Schwab, Claire, Ryan, Sarra L., Papaemmanuil, Elli, Robinson, Hazel M., Jacobs, Patricia, Moorman, Anthony V., Dyer, Sara, Borrow, Julian, Griffiths, Mike, Heerema, Nyla A., Carroll, Andrew J., Talley, Polly, Bown, Nick, Telford, Nick, Ross, Fiona M., Gaunt, Lorraine, McNally, Richard J. Q., Young, Bryan D., Sinclair, Paul, Rand, Vikki, Teixeira, Manuel R., Joseph, Olivia, Robinson, Ben, Maddison, Mark, Dastugue, Nicole, Vandenberghe, Peter, Haferlach, Claudia, Stephens, Philip J., Cheng, Jiqiu, Van Loo, Peter, Stratton, Michael R., Campbell, Peter J., Harrison, Christine J.

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Whole exome sequencing of adenoid cystic carcinoma von Stephens, Philip J, Davies, Helen R, Mitani, Yoshitsugu, Van Loo, Peter, Shlien, Adam, Tarpey, Patrick S, Papaemmanuil, Elli, Cheverton, Angela, Bignell, Graham R, Butler, Adam P, Gamble, John, Gamble, Stephen, Hardy, Claire, Hinton, Jonathan, Jia, Mingming, Jayakumar, Alagu, Jones, David, Latimer, Calli, McLaren, Stuart, McBride, David J, Menzies, Andrew, Mudie, Laura, Maddison, Mark, Raine, Keiran, Nik-Zainal, Serena, O'Meara, Sarah, Teague, Jon W, Varela, Ignacio, Wedge, David C, Whitmore, Ian, Lippman, Scott M, McDermott, Ultan, Stratton, Michael R, Campbell, Peter J, El-Naggar, Adel K, Futreal, P Andrew

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A systematic, large-scale resequencing screen of X-chromosome coding exons in mental retardation von Teague, Jon, Van Esch, Hilde, Carvill, Gemma, Richardson, David, Varian, Jennifer, Wooster, Richard, Stratton, Michael R, O'Meara, Sarah, Hardy, Claire, Shepherd, Rebecca, Bobrow, Martin, Gardner, Alison, Abidi, Fatima E, Srivastava, Anand K, Fullston, Tod, Cole, Jennifer, Jenkinson, Andrew, Buck, Gemma, Tarpey, Patrick S, Futreal, P Andrew, Latimer, Calli, Turrell, Kelly, Jia, Mingming, Corbett, Mark, Boyle, Jackie, Luo, Ying, Partington, Michael, Gecz, Jozef, van Bokhoven, Hans, Andrews, Jenny, Blow, Matt, de Brouwer, Arjan P M, Cox, James, Whibley, Annabel, Rujirabanjerd, Sinitdhorn, Moon, Jenny, Mallya, Uma, Gray, Kristian, Dunmore, Rebecca, Smith, Raffaella, Shoubridge, Cheryl, Turner, Rachel, Menzies, Andrew, Maddison, Mark, Hackett, Anna, Barthorpe, Syd, Martinez, Francisco, Turner, Gillian, Parnau, Josef, Jones, David, Vandeleur, Lucianne, Chelly, Jamel, Haan, Eric, Greenman, Chris, Thompson, Deborah, Mohammed, Shehla, Skinner, Cindy, Mironenko, Tatiana, Ropers, Hans-Hilger, Xue, Yali, Field, Michael, Shaw, Marie, Tyler-Smith, Chris, Tolmie, John L, Edkins, Sarah, Pleasance, Erin, Stevenson, Roger E, Schwartz, Charles E, Widaa, Sara, Stephens, Phil, Goliath, Rene, Raynaud, Martine, Easton, Douglas F, Dicks, Ed, Butler, Adam, Raymond, F Lucy, Wray, Paul, Tejada, M Isabel, West, Sofie

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Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer von Stratton, Michael R, Futreal, P Andrew, van Haaften, Gijs, Dalgliesh, Gillian L, Davies, Helen, Chen, Lina, Bignell, Graham, Greenman, Chris, Edkins, Sarah, Hardy, Claire, O'Meara, Sarah, Teague, Jon, Butler, Adam, Hinton, Jonathan, Latimer, Calli, Andrews, Jenny, Barthorpe, Syd, Beare, Dave, Buck, Gemma, Campbell, Peter J, Cole, Jennifer, Forbes, Simon, Jia, Mingming, Jones, David, Kok, Chai Yin, Leroy, Catherine, Lin, Meng-Lay, McBride, David J, Maddison, Mark, Maquire, Simon, McLay, Kirsten, Menzies, Andrew, Mironenko, Tatiana, Mulderrig, Lee, Mudie, Laura, Pleasance, Erin, Shepherd, Rebecca, Smith, Raffaella, Stebbings, Lucy, Stephens, Philip, Tang, Gurpreet, Tarpey, Patrick S, Turner, Rachel, Turrell, Kelly, Varian, Jennifer, West, Sofie, Widaa, Sara, Wray, Paul, Collins, V Peter, Ichimura, Koichi, Law, Simon, Wong, John, Yuen, Siu Tsan, Leung, Suet Yi, Tonon, Giovanni, DePinho, Ronald A, Tai, Yu-Tzu, Anderson, Kenneth C, Kahnoski, Richard J, Massie, Aaron, Khoo, Sok Kean, Teh, Bin Tean

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Genomic Plasticity of the Causative Agent of Melioidosis, Burkholderia pseudomallei von Matthew T. G. Holden, Titball, Richard W., Peacock, Sharon J., Cerdeño-Tárraga, Ana M., Atkins, Timothy, Crossman, Lisa C., Pitt, Tyrone, Churcher, Carol, Mungall, Karen, Bentley, Stephen D., Sebaihia, Mohammed, Thomson, Nicholas R., Bason, Nathalie, Beacham, Ifor R., Brooks, Karen, Brown, Katherine A., Brown, Nat F., Challis, Greg L., Cherevach, Inna, Chillingworth, Tracy, Cronin, Ann, Crossett, Ben, Davis, Paul, DeShazer, David, Feltwell, Theresa, Fraser, Audrey, Hance, Zahra, Hauser, Heidi, Holroyd, Simon, Jagels, Kay, Keith, Karen E., Maddison, Mark, Moule, Sharon, Price, Claire, Quail, Michael A., Rabbinowitsch, Ester, Rutherford, Kim, Sanders, Mandy, Simmonds, Mark, Songsivilai, Sirirurg, Stevens, Kim, Tumapa, Sarinna, Vesaratchavest, Monkgol, Whitehead, Sally, Yeats, Corin, Barrell, Bart G., Petra C. F. Oyston, Parkhill, Julian, Greenberg, E. Peter

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Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells von Ju, Young Seok, Tubio, Jose M C, Mifsud, William, Fu, Beiyuan, Davies, Helen R, Ramakrishna, Manasa, Li, Yilong, Yates, Lucy, Gundem, Gunes, Tarpey, Patrick S, Behjati, Sam, Papaemmanuil, Elli, Martin, Sancha, Fullam, Anthony, Gerstung, Moritz, Nangalia, Jyoti, Green, Anthony R, Caldas, Carlos, Borg, Åke, Tutt, Andrew, Lee, Ming Ta Michael, van't Veer, Laura J, Tan, Benita K T, Aparicio, Samuel, Span, Paul N, Martens, John W M, Knappskog, Stian, Vincent-Salomon, Anne, Børresen-Dale, Anne-Lise, Eyfjörd, Jórunn Erla, Myklebost, Ola, Flanagan, Adrienne M, Foster, Christopher, Neal, David E, Cooper, Colin, Eeles, Rosalind, Bova, Steven G, Lakhani, Sunil R, Desmedt, Christine, Thomas, Gilles, Richardson, Andrea L, Purdie, Colin A, Thompson, Alastair M, McDermott, Ultan, Yang, Fengtang, Nik-Zainal, Serena, Campbell, Peter J, Stratton, Michael R

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Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tis... von Cooper, Colin S, Eeles, Rosalind, Wedge, David C, Van Loo, Peter, Gundem, Gunes, Alexandrov, Ludmil B, Kremeyer, Barbara, Butler, Adam, Lynch, Andrew G, Camacho, Niedzica, Massie, Charlie E, Kay, Jonathan, Luxton, Hayley J, Edwards, Sandra, Kote-Jarai, Zsofia, Dennis, Nening, Merson, Sue, Leongamornlert, Daniel, Zamora, Jorge, Corbishley, Cathy, Thomas, Sarah, Nik-Zainal, Serena, Ramakrishna, Manasa, O'Meara, Sarah, Matthews, Lucy, Clark, Jeremy, Hurst, Rachel, Mithen, Richard, Bristow, Robert G, Boutros, Paul C, Fraser, Michael, Cooke, Susanna, Raine, Keiran, Jones, David, Menzies, Andrew, Stebbings, Lucy, Hinton, Jon, Teague, Jon, McLaren, Stuart, Mudie, Laura, Hardy, Claire, Anderson, Elizabeth, Joseph, Olivia, Goody, Victoria, Robinson, Ben, Maddison, Mark, Gamble, Stephen, Greenman, Christopher, Berney, Dan, Hazell, Steven, Livni, Naomi, Fisher, Cyril, Ogden, Christopher, Kumar, Pardeep, Thompson, Alan, Woodhouse, Christopher, Nicol, David, Mayer, Erik, Dudderidge, Tim, Shah, Nimish C, Gnanapragasam, Vincent, Voet, Thierry, Campbell, Peter, Futreal, Andrew, Easton, Douglas, Warren, Anne Y, Foster, Christopher S, Stratton, Michael R, Whitaker, Hayley C, McDermott, Ultan, Brewer, Daniel S, Neal, David E

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