Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism von Johnson, Marc O., Wolf, Melissa M., Madden, Matthew Z., Andrejeva, Gabriela, Sugiura, Ayaka, Contreras, Diana C., Maseda, Damian, Liberti, Maria V., Paz, Katelyn, Kishton, Rigel J., Johnson, Matthew E., de Cubas, Aguirre A., Wu, Pingsheng, Li, Gongbo, Zhang, Yongliang, Newcomb, Dawn C., Wells, Andrew D., Restifo, Nicholas P., Rathmell, W. Kimryn, Locasale, Jason W., Davila, Marco L., Blazar, Bruce R., Rathmell, Jeffrey C.

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SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination von Daddacha, Waaqo, Koyen, Allyson E., Bastien, Amanda J., Head, PamelaSara E., Dhere, Vishal R., Nabeta, Geraldine N., Connolly, Erin C., Werner, Erica, Madden, Matthew Z., Daly, Michele B., Minten, Elizabeth V., Whelan, Donna R., Schlafstein, Ashley J., Zhang, Hui, Anand, Roopesh, Doronio, Christine, Withers, Allison E., Shepard, Caitlin, Sundaram, Ranjini K., Deng, Xingming, Dynan, William S., Wang, Ya, Bindra, Ranjit S., Cejka, Petr, Rothenberg, Eli, Doetsch, Paul W., Kim, Baek, Yu, David S.

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EZH2 has a non-catalytic and PRC2-independent role in stabilizing DDB2 to promote nucleotide excision repair von Koyen, Allyson E., Madden, Matthew Z., Park, Dongkyoo, Minten, Elizabeth V., Kapoor-Vazirani, Priya, Werner, Erica, Pfister, Neil T., Haji-Seyed-Javadi, Ramona, Zhang, Hui, Xu, Jie, Deng, Nikita, Duong, Duc M., Pecen, Turner J., Frazier, Zoë, Nagel, Zachary D., Lazaro, Jean-Bernard, Mouw, Kent W., Seyfried, Nicholas T., Moreno, Carlos S., Owonikoko, Taofeek K., Deng, Xingming, Yu, David S.

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The Complex Integration of T-cell Metabolism and Immunotherapy von Madden, Matthew Z, Rathmell, Jeffrey C

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Stimulating TAM-mediated anti-tumor immunity with mannose-decorated nanoparticles in ovarian cancer von Glass, Evan B, Hoover, Alyssa A, Bullock, Kennady K, Madden, Matthew Z, Reinfeld, Bradley I, Harris, Whitney, Parker, Dominique, Hufnagel, Demetra H, Crispens, Marta A, Khabele, Dineo, Rathmell, W Kimryn, Rathmell, Jeffrey C, Wilson, Andrew J, Giorgio, Todd D, Yull, Fiona E

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ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA von Zhang, Hui, Head, PamelaSara E., Daddacha, Waaqo, Park, Seong-Hoon, Li, Xingzhe, Pan, Yunfeng, Madden, Matthew Z., Duong, Duc M., Xie, Maohua, Yu, Bing, Warren, Matthew D., Liu, Elaine A., Dhere, Vishal R., Li, Chunyang, Pradilla, Ivan, Torres, Mylin A., Wang, Ya, Dynan, William S., Doetsch, Paul W., Deng, Xingming, Seyfried, Nicholas T., Gius, David, Yu, David S.

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Structural variation of the 3-acetamido-4,5,6-trihydroxyazepane iminosugar through epimerization and C -alkylation leads to low micromolar HexAB and NagZ inhibitors von Bouquet, J, Auberger, N, Ashmus, R, King, D, Bordes, A, Fontelle, N, Nakagawa, S, Madden, Z, Proceviat, C, Kato, A, Désiré, J, Vocadlo, D J, Blériot, Y

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Cell-programmed nutrient partitioning in the tumour microenvironment von Reinfeld, Bradley I., Madden, Matthew Z., Wolf, Melissa M., Chytil, Anna, Bader, Jackie E., Patterson, Andrew R., Sugiura, Ayaka, Cohen, Allison S., Ali, Ahmed, Do, Brian T., Muir, Alexander, Lewis, Caroline A., Hongo, Rachel A., Young, Kirsten L., Brown, Rachel E., Todd, Vera M., Huffstater, Tessa, Abraham, Abin, O’Neil, Richard T., Wilson, Matthew H., Xin, Fuxue, Tantawy, M. Noor, Merryman, W. David, Johnson, Rachelle W., Williams, Christopher S., Mason, Emily F., Mason, Frank M., Beckermann, Katherine E., Vander Heiden, Matthew G., Manning, H. Charles, Rathmell, Jeffrey C., Rathmell, W. Kimryn

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Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response von Levine, Lauren S., Hiam-Galvez, Kamir J., Marquez, Diana M., Tenvooren, Iliana, Madden, Matthew Z., Contreras, Diana C., Dahunsi, Debolanle O., Irish, Jonathan M., Oluwole, Olalekan O., Rathmell, Jeffrey C., Spitzer, Matthew H.

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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function von Sugiura, Ayaka, Andrejeva, Gabriela, Voss, Kelsey, Heintzman, Darren R., Xu, Xincheng, Madden, Matthew Z., Ye, Xiang, Beier, Katherine L., Chowdhury, Nowrin U., Wolf, Melissa M., Young, Arissa C., Greenwood, Dalton L., Sewell, Allison E., Shahi, Shailesh K., Freedman, Samantha N., Cameron, Alanna M., Foerch, Patrik, Bourne, Tim, Garcia-Canaveras, Juan C., Karijolich, John, Newcomb, Dawn C., Mangalam, Ashutosh K., Rabinowitz, Joshua D., Rathmell, Jeffrey C.

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Leptin Augments Antitumor Immunity in Obesity by Repolarizing Tumor-Associated Macrophages von Dudzinski, Stephanie O, Bader, Jackie E, Beckermann, Kathryn E, Young, Kirsten L, Hongo, Rachel, Madden, Matthew Z, Abraham, Abin, Reinfeld, Bradley I, Ye, Xiang, MacIver, Nancie J, Giorgio, Todd D, Rathmell, Jeffrey C

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Macrophages Promote Aortic Valve Cell Calcification and Alter STAT3 Splicing von Raddatz, Michael A., Huffstater, Tessa, Bersi, Matthew R., Reinfeld, Bradley I., Madden, Matthew Z., Booton, Sabrina E., Rathmell, W. Kimryn, Rathmell, Jeffrey C., Lindman, Brian R., Madhur, Meena S., Merryman, W. David

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Differential Effects of Glutamine Inhibition Strategies on Antitumor CD8 T Cells von Madden, Matthew Z, Ye, Xiang, Chi, Channing, Fisher, Emilie L, Wolf, Melissa M, Needle, Gabriel A, Bader, Jackie E, Patterson, Andrew R, Reinfeld, Bradley I, Landis, Madelyn D, Hathaway, Emma S, Muka, Jason E, O'Neil, Richard T, Karijolich, John, Philip, Mary, Rathmell, Jeffrey C

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Obesity induces PD-1 on macrophages to suppress anti-tumour immunity von Bader, Jackie E., Wolf, Melissa M., Lupica-Tondo, Gian Luca, Madden, Matthew Z., Reinfeld, Bradley I., Arner, Emily N., Hathaway, Emma S., Steiner, KayLee K., Needle, Gabriel A., Hatem, Zaid, Landis, Madelyn D., Faneuff, Eden E., Blackman, Amondrea, Wolf, Elysa M., Cottam, Matthew A., Ye, Xiang, Bates, Madison E., Smart, Kyra, Wang, Wenjun, Pinheiro, Laura V., Christofides, Anthos, Smith, DuPreez, Boussiotis, Vassiliki A., Haake, Scott M., Beckermann, Kathryn E., Wellen, Kathryn E., Reinhart-King, Cynthia A., Serezani, C. Henrique, Lee, Cheng-Han, Aubrey, Christa, Chen, Heidi, Rathmell, W. Kimryn, Hasty, Alyssa H., Rathmell, Jeffrey C.

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Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation von Healey, Diana C Contreras, Cephus, Jacqueline Y, Barone, Sierra M, Chowdhury, Nowrin U, Dahunsi, Debolanle O, Madden, Matthew Z, Ye, Xiang, Yu, Xuemei, Olszewski, Kellen, Young, Kirsten, Gerriets, Valerie A, Siska, Peter J, Dworski, Ryszard, Hemler, Jonathan, Locasale, Jason W, Poyurovsky, Masha V, Peebles, Jr, R Stokes, Irish, Jonathan M, Newcomb, Dawn C, Rathmell, Jeffrey C

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Androgen signaling restricts glutaminolysis to drive sex-specific Th17 metabolism in allergic airway inflammation von Chowdhury, Nowrin U, Cephus, Jacqueline-Yvonne, Henriquez Pilier, Emely, Wolf, Melissa M, Madden, Matthew Z, Kuehnle, Shelby N, McKernan, Kaitlin E, Jennings, Erin Q, Arner, Emily N, Heintzman, Darren R, Chi, Channing, Sugiura, Ayaka, Stier, Matthew T, Voss, Kelsey, Ye, Xiang, Scales, Kennedi, Krystofiak, Evan S, Gandhi, Vivek D, Guzy, Robert D, Cahill, Katherine N, Sperling, Anne I, Peebles, Jr, R Stokes, Rathmell, Jeffrey C, Newcomb, Dawn C

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VHL loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesis von Wolf, Melissa M, Madden, Matthew Z, Arner, Emily N, Bader, Jackie E, Ye, Xiang, Vlach, Logan, Tigue, Megan L, Landis, Madelyn D, Jonker, Patrick B, Hatem, Zaid, Steiner, KayLee K, Gaines, Dakim K, Reinfeld, Bradley I, Hathaway, Emma S, Xin, Fuxue, Tantawy, M Noor, Haake, Scott M, Jonasch, Eric, Muir, Alexander, Weiss, Vivian L, Beckermann, Kathryn E, Rathmell, W Kimryn, Rathmell, Jeffrey C

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Author Correction: Obesity induces PD-1 on macrophages to suppress anti-tumour immunity von Bader, Jackie E., Wolf, Melissa M., Lupica-Tondo, Gian Luca, Madden, Matthew Z., Reinfeld, Bradley I., Arner, Emily N., Hathaway, Emma S., Steiner, KayLee K., Needle, Gabriel A., Hatem, Zaid, Landis, Madelyn D., Faneuff, Eden E., Blackman, Amondrea, Wolf, Elysa M., Cottam, Matthew A., Ye, Xiang, Bates, Madison E., Smart, Kyra, Wang, Wenjun, Pinheiro, Laura V., Christofides, Anthos, Smith, DuPreez, Boussiotis, Vassiliki A., Haake, Scott M., Beckermann, Kathryn E., Wellen, Kathryn E., Reinhart-King, Cynthia A., Serezani, C. Henrique, Lee, Cheng-Han, Aubrey, Christa, Chen, Heidi, Rathmell, W. Kimryn, Hasty, Alyssa H., Rathmell, Jeffrey C.

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A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress response von Smith, Scott C, Petrova, Aleksandra V, Madden, Matthew Z, Wang, Hongyan, Pan, Yunfeng, Warren, Matthew D, Hardy, Claire W, Liang, Dong, Liu, Elaine A, Robinson, M Hope, Rudra, Soumon, Wang, Jie, Ehdaivand, Shahrzad, Torres, Mylin A, Wang, Ya, Yu, David S

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CHD7 Expression Predicts Survival Outcomes in Patients with Resected Pancreatic Cancer von COLBERT, Lauren E, PETROVA, Aleksandra V, SAKA, Burcu, HALL, William A, SHELTON, Joseph W, GANDHI, Khanjan, PAULY, Rini, KOWALSKI, Jeanne, KOOBY, David A, EL-RAYES, Bassel F, STALEY, Charles A, ADSAY, N. Volkan, FISHER, Sarah B, CURRAN, Walter J, LANDRY, Jerome C, MAITHEL, Shishir K, YU, David S, PANTAZIDES, Brooke G, MADDEN, Matthew Z, HARDY, Claire W, WARREN, Matthew D, YUNFENG PAN, NAGARAJU, Ganji P, LIU, Elaine A

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