A link between mitotic entry and membrane growth suggests a novel model for cell size control von Anastasia, Steph D, Nguyen, Duy Linh, Thai, Vu, Meloy, Melissa, MacDonough, Tracy, Kellogg, Douglas R

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Nucleoporin mediated nuclear positioning and silencing of HMR von Ruben, Giulia J, Kirkland, Jacob G, MacDonough, Tracy, Chen, Miao, Dubey, Rudra N, Gartenberg, Marc R, Kamakaka, Rohinton T

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Chemoradiation therapy alters the PD-L1 score in locoregional recurrent squamous cell carcinomas of the head and neck von Park, Brian J., Mattox, Austin K., Clayburgh, Daniel, Patel, Mihir, Bell, R. Bryan, Yueh, Bevan, Leidner, Rom, Xiao, Hong, Couey, Marcus, Li, Shiting, Qin, Tingting, Sartor, Maureen A., Cairns, Belinda, MacDonough, Tracy, Halliwill, Kyle, Deschler, Daniel, Lin, Derrick T., Faquin, William C., Sadow, Peter M., Pai, Sara I.

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An anti-PD-1-GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy von Chan, Sarah, Belmar, Nicole, Ho, Sun, Rogers, Bryan, Stickler, Marcia, Graham, Michelle, Lee, Eileen, Tran, Ninian, Zhang, Dong, Gupta, Priyanka, Sho, Mien, MacDonough, Tracy, Woolley, Andrew, Kim, Han, Zhang, Hong, Liu, Wei, Zheng, Pingping, Dezso, Zoltan, Halliwill, Kyle, Ceccarelli, Michele, Rhodes, Susan, Thakur, Archana, Forsyth, Charles M, Xiong, Mengli, Tan, Siu Sze, Iyer, Ramesh, Lake, Marc, Digiammarino, Enrico, Zhou, Li, Bigelow, Lance, Longenecker, Kenton, Judge, Russell A, Liu, Cassie, Trumble, Max, Remis, Jonathan P, Fox, Melvin, Cairns, Belinda, Akamatsu, Yoshiko, Hollenbaugh, Diane, Harding, Fiona, Alvarez, Hamsell M

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PP2A^sup Rts1^ is a master regulator of pathways that control cell size von Zapata, Jessica, Dephoure, Noah, MacDonough, Tracy, Yu, Yaxin, Parnell, Emily J, Mooring, Meghan, Gygi, Steven P, Stillman, David J, Kellogg, Douglas R

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PP2ARts1 is a master regulator of pathways that control cell size von Zapata, Jessica, Dephoure, Noah, MacDonough, Tracy, Yu, Yaxin, Parnell, Emily J, Mooring, Meghan, Gygi, Steven P, Stillman, David J, Kellogg, Douglas R

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PP2ARts1 is a master regulator of pathways that control cell size von Zapata, Jessica, Dephoure, Noah, Macdonough, Tracy, Yu, Yaxin, Parnell, Emily J, Mooring, Meghan, Gygi, Steven P, Stillman, David J, Kellogg, Douglas R

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Synthesis and biological evaluation of indole-based, anti-cancer agents inspired by the vascular disrupting agent 2-(3′-hydroxy-4′-methoxyphenyl)-3-(3″,4″,5″-trimethoxybenzoyl)-6-m... von MacDonough, Matthew T., Strecker, Tracy E., Hamel, Ernest, Hall, John J., Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.

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Bioreductively Activatable Prodrug Conjugates of Combretastatin A‑1 and Combretastatin A‑4 as Anticancer Agents Targeted toward Tumor-Associated Hypoxia von Winn, Blake A, Devkota, Laxman, Kuch, Bunnarack, MacDonough, Matthew T, Strecker, Tracy E, Wang, Yifan, Shi, Zhe, Gerberich, Jeni L, Mondal, Deboprosad, Ramirez, Alejandro J, Hamel, Ernest, Chaplin, David J, Davis, Peter, Mason, Ralph P, Trawick, Mary Lynn, Pinney, Kevin G

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Synthesis of structurally diverse benzosuberene analogues and their biological evaluation as anti-cancer agents von Tanpure, Rajendra P., George, Clinton S., Strecker, Tracy E., Devkota, Laxman, Tidmore, Justin K., Lin, Chen-Ming, Herdman, Christine A., MacDonough, Matthew T., Sriram, Madhavi, Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.

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The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts von Strecker, Tracy E, Odutola, Samuel O, Lopez, Ramona, Cooper, Morgan S, Tidmore, Justin K, Charlton-Sevcik, Amanda K, Li, Li, MacDonough, Matthew T, Hadimani, Mallinath B, Ghatak, Anjan, Liu, Li, Chaplin, David J, Mason, Ralph P, Pinney, Kevin G, Trawick, Mary Lynn

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Synthesis of a 2‑Aryl-3-aroyl Indole Salt (OXi8007) Resembling Combretastatin A‑4 with Application as a Vascular Disrupting Agent von Hadimani, Mallinath B, MacDonough, Matthew T, Ghatak, Anjan, Strecker, Tracy E, Lopez, Ramona, Sriram, Madhavi, Nguyen, Benson L, Hall, John J, Kessler, Raymond J, Shirali, Anupama R, Liu, Li, Garner, Charles M, Pettit, George R, Hamel, Ernest, Chaplin, David J, Mason, Ralph P, Trawick, Mary Lynn, Pinney, Kevin G

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Mechanism of action of the vascular disrupting agent OXi8006 on activated endothelial cell signaling von Taylor, Emily A., Odutola, Sam O., Strecker, Tracy E., Hayashi, Merrick M., MacDonough, Matthew T., Pinney, Kevin G., Trawick, Mary Lynn

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Bioreductively Activatable Prodrug Conjugates of Combretastatin A-1 and Combretastatin A-4 as Anticancer Agents Targeted Towards Tumor-Associated Hypoxia von Winn, Blake A., Devkota, Laxman, Kuch, Bunnarack, MacDonough, Matthew T., Strecker, Tracy E., Wang, Yifan, Shi, Zhe, Gerberich, Jeni L., Mondal, Deboprosad, Ramirez, Alejandro J., Hamel, Ernest, Chaplin, David J., Davis, Peter, Mason, Ralph P., Trawick, Mary Lynn, Pinney, Kevin G.

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Design, synthesis, and biological evaluation of potent thiosemicarbazone based cathepsin L inhibitors von Kishore Kumar, G.D., Chavarria, Gustavo E., Charlton-Sevcik, Amanda K., Arispe, Wara M., MacDonough, Matthew T., Strecker, Tracy E., Chen, Shen-En, Siim, Bronwyn G., Chaplin, David J., Trawick, Mary Lynn, Pinney, Kevin G.

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Abstract 3203: Targeting tumor hypoxia with prodrug conjugates of potent small-molecule inhibitors of tubulin polymerization von Pinney, Kevin G., Trawick, Mary Lynn, Mason, Ralph P., Liu, Li, Chaplin, David J., Winn, Blake A., Devkota, Laxman, Strecker, Tracy E., Gerberich, Jeni, Winters, Alex, Wang, Yifan, MacDonough, Matthew T.

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Effects of the Vascular Disrupting Agent OXi8006 on Activated Endothelial Cell Signaling and Tumor Growth Delay in a Breast Cancer Mouse Model Treated with the Corresponding Phosph... von Odutola, Samuel O., Strecker, Tracy E., Taylor, Emily A., Schwartze, Jeffrey, Gerberich, Jeni, MacDonough, Matthew T., Chaplin, David J., Liu, Li, Mason, Ralph P., Pinney, Kevin G., Trawick, Mary Lynn

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Vascular Disrupting Activity of OXi8006 in Endothelial Cells and Its Phosphate Prodrug OXi8007 in Breast Tumor Xenografts in Vivo von Odutola, Samuel, Strecker, Tracy, Cooper, Morgan, Tidmore, Justin, Charlton‐Sevcik, Amanda, MacDonough, Matthew, Hadimani, Mallinath, Ghatak, Anjan, Lopez, Ramona, Li, Li, Liu, Li, Mason, Ralph, Chaplin, David, Pinney, Kevin, Trawick, Mary Lynn

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