Extensive transcriptional and chromatin changes underlie astrocyte maturation in vivo and in culture von Lattke, Michael, Goldstone, Robert, Ellis, James K., Boeing, Stefan, Jurado-Arjona, Jerónimo, Marichal, Nicolás, MacRae, James I., Berninger, Benedikt, Guillemot, Francois

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Antioxidant Role for Lipid Droplets in a Stem Cell Niche of Drosophila von Bailey, Andrew P., Koster, Grielof, Guillermier, Christelle, Hirst, Elizabeth M.A., MacRae, James I., Lechene, Claude P., Postle, Anthony D., Gould, Alex P.

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Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells von Haythorne, Elizabeth, Rohm, Maria, van de Bunt, Martijn, Brereton, Melissa F., Tarasov, Andrei I., Blacker, Thomas S., Sachse, Gregor, Silva dos Santos, Mariana, Terron Exposito, Raul, Davis, Simon, Baba, Otto, Fischer, Roman, Duchen, Michael R., Rorsman, Patrik, MacRae, James I., Ashcroft, Frances M.

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A malaria parasite phospholipase facilitates efficient asexual blood stage egress von Ramaprasad, Abhinay, Burda, Paul-Christian, Koussis, Konstantinos, Thomas, James A, Pietsch, Emma, Calvani, Enrica, Howell, Steven A, MacRae, James I, Snijders, Ambrosius P, Gilberger, Tim-Wolf, Blackman, Michael J

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Mitochondrial Metabolism of Glucose and Glutamine Is Required for Intracellular Growth of Toxoplasma gondii von MacRae, James I., Sheiner, Lilach, Nahid, Amsha, Tonkin, Christopher, Striepen, Boris, McConville, Malcolm J.

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A review of the pharmaceutical exposome in aquatic fauna von Miller, Thomas H., Bury, Nicolas R., Owen, Stewart F., MacRae, James I., Barron, Leon P.

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Prediction of bioconcentration factors in fish and invertebrates using machine learning von Miller, Thomas H., Gallidabino, Matteo D., MacRae, James I., Owen, Stewart F., Bury, Nicolas R., Barron, Leon P.

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Single-cell resolved imaging reveals intra-tumor heterogeneity in glycolysis, transitions between metabolic states, and their regulatory mechanisms von Kondo, Hiroshi, Ratcliffe, Colin D.H., Hooper, Steven, Ellis, James, MacRae, James I., Hennequart, Marc, Dunsby, Christopher W., Anderson, Kurt I., Sahai, Erik

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PHGDH is required for germinal center formation and is a therapeutic target in MYC-driven lymphoma von D'Avola, Annalisa, Legrave, Nathalie, Tajan, Mylène, Chakravarty, Probir, Shearer, Ryan L, King, Hamish W, Kluckova, Katarina, Cheung, Eric C, Clear, Andrew J, Gunawan, Arief S, Zhang, Lingling, James, Louisa K, MacRae, James I, Gribben, John G, Calado, Dinis P, Vousden, Karen H, Riches, John C

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Reduced cholesterol levels impair Smoothened activation in Smith-Lemli-Opitz syndrome von Blassberg, Robert, Macrae, James I, Briscoe, James, Jacob, John

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Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism von Bussi, Claudio, Heunis, Tiaan, Pellegrino, Enrica, Bernard, Elliott M., Bah, Nourdine, Dos Santos, Mariana Silva, Santucci, Pierre, Aylan, Beren, Rodgers, Angela, Fearns, Antony, Mitschke, Julia, Moore, Christopher, MacRae, James I., Greco, Maria, Reinheckel, Thomas, Trost, Matthias, Gutierrez, Maximiliano G.

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Use cases, best practice and reporting standards for metabolomics in regulatory toxicology von Viant, Mark R., Ebbels, Timothy M. D., Beger, Richard D., Ekman, Drew R., Epps, David J. T., Kamp, Hennicke, Leonards, Pim E. G., Loizou, George D., MacRae, James I., van Ravenzwaay, Bennard, Rocca-Serra, Philippe, Salek, Reza M., Walk, Tilmann, Weber, Ralf J. M.

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Metabolic priming by multiple enzyme systems supports glycolysis, HIF1α stabilisation, and human cancer cell survival in early hypoxia von Grimm, Fiona, Asuaje, Agustín, Jain, Aakriti, Silva dos Santos, Mariana, Kleinjung, Jens, Nunes, Patrícia M, Gehrig, Stefanie, Fets, Louise, Darici, Salihanur, MacRae, James I, Anastasiou, Dimitrios

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Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis von Sterkel, Marcos, Haines, Lee R., Casas-Sanchez, Aitor, Owino Adung'a, Vincent, Vionette-Amaral, Raquel J., Quek, Shannon, Rose, Clair, Silva dos Santos, Mariana, Garcia Escude, Natalia, Ismail, Hanafy M., Paine, Mark I., Barribeau, Seth M., Wagstaff, Simon, MacRae, James I., Masiga, Daniel, Yakob, Laith, Oliveira, Pedro L., Acosta-Serrano, Alvaro

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Stage-Specific Changes in Plasmodium Metabolism Required for Differentiation and Adaptation to Different Host and Vector Environments von Srivastava, Anubhav, Philip, Nisha, Hughes, Katie R, Georgiou, Konstantina, MacRae, James I, Barrett, Michael P, Creek, Darren J, McConville, Malcolm J, Waters, Andrew P

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BCKDH: the missing link in apicomplexan mitochondrial metabolism is required for full virulence of Toxoplasma gondii and Plasmodium berghei von Oppenheim, Rebecca D, Creek, Darren J, Macrae, James I, Modrzynska, Katarzyna K, Pino, Paco, Limenitakis, Julien, Polonais, Valerie, Seeber, Frank, Barrett, Michael P, Billker, Oliver, McConville, Malcolm J, Soldati-Favre, Dominique

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Subcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages von Greenwood, Daniel J, Dos Santos, Mariana Silva, Huang, Song, Russell, Matthew R G, Collinson, Lucy M, MacRae, James I, West, Andy, Jiang, Haibo, Gutierrez, Maximiliano G

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Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells von Ch, Ratnasekhar, Rey, Guillaume, Ray, Sandipan, Jha, Pawan K., Driscoll, Paul C., Dos Santos, Mariana Silva, Malik, Dania M., Lach, Radoslaw, Weljie, Aalim M., MacRae, James I., Valekunja, Utham K., Reddy, Akhilesh B.

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Developmental diet regulates Drosophila lifespan via lipid autotoxins von Stefana, M. Irina, Driscoll, Paul C., Obata, Fumiaki, Pengelly, Ana Raquel, Newell, Clare L., MacRae, James I., Gould, Alex P.

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Cryogenic OrbiSIMS Localizes Semi‐Volatile Molecules in Biological Tissues von Newell, Clare L., Vorng, Jean‐Luc, MacRae, James I., Gilmore, Ian S., Gould, Alex P.

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