Uncovering Salient Cellular Heterogeneity in Human Lung Transplantation Using Single-Cell RNA Sequencing von Moshkelgosha, S., Duong, A., Berra, G., Renaud, B., Daigneault, T., Wilson, G., Keshavjee, S., Yeung, J., MacParland, S., Martinu, T., Juvet, S.

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Antagonistic expression of hepatitis C virus and alpha interferon in lymphoid cells during persistent occult infection von Pham, T. N. Q., Mulrooney-Cousins, P. M., Mercer, S. E., MacParland, S. A., Inglot, M., Zalewska, M., Simon, K., Michalak, T. I.

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Regulatory B cells are induced in untreated HIV-1 infection and suppress HIV-1 specific T cell responses von Liu, J, Zhan, W, Kim, C, Lee, E, Cao, J, Ziegler, B, Gregor, A, Yue, F, Huibner, S, Macparland, S, Clayton, K, Schwartz, J, Song, H, Bento, E, Kovacs, C, Kaul, R, Ostrowski, M

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Pulmonary Macrophage Subsets Associated with Lung Allograft Dysfunction Revealed by Single-Cell RNA Sequencing von Moshkelgosha, S., Duong, A., Wilson, G.W., Andrews, T., Renaud-Picard, B., Berra, G., Daigneault, T., Liu, M., Keshavjee, S., Yeung, J., Macparland, S., Martinu, T., Juvet, S.C.

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OC 27.1 Kupffer Cells are Required for Platelet-Mediated Hepatocellular TPO Generation von Karakas, D., Li, J., Ma, W., Masoud, M., Shen, C., MacParland, S., Kahr, W., Ni, H.

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Classification of variants of reduced penetrance in high-penetrance cancer susceptibility genes: Framework for genetics clinicians and clinical scientists by CanVIG-UK (Cancer Vari... von Allen, Sophie, Durkie, Miranda, Burghel, George J., Palmer-Smith, Sheila, McDevitt, Trudi, Garrett, A., Loong, L., Torr, B., Allen, S., Berry, I.R., Eccles, D.M., Tischkowitz, M., Evans, D.G., Lalloo, F., Kumar, A., Ross, A., Hogg, A.C., McIldowie, B., Olimpio, C., Clabby, C., Byrne, C., Moore, D., Donnelly, D., Atkinson, E., Johnston, E., Powell, H., Hoyle, J., Murray, J., Callaway, J., Murphy, K., Cadoo, K., Brown, K., Reay, K., McKay Bounford, K., Bradshaw, K., Reed, L., Hawkes, L., Kiely, L., Side, L., Shanmugasundaram, M., Duff, M., Ahmed, M., O'Brien, C., Middleton, O., Logan, P., Tredwell, R., Harrison, R., Nyanhete, R., Davidson, R., Butler, S., Dell, S., Greville-Heygate, S., Tennant, S., McVeigh, T., Clowes, V., Kemp, Z., Joyce, C., Timbs, A., Husher, C., Reay, D., Harper, J., Linton-Willoughby, T., Watt, C., Mitchell, R., Nickless, G., McCarthy, C., Botosneanu, S., Sherlaw, C., Forde, C., Petley, E., Braham, R., Hanington, L., Irving, R., Gabriel, J., Chiecchio, L., Cloke, V., Pleasance, B., Whitehouse, H., Sau, C., Massey, H., Gillespie, K., Alder, A., Cassidy, C., Orfali, N., Luharia, A., Andreou, A., Edis, M., Callard, A., Ostrowski, P., Freestone, L., Whitworth, A., Mutch, S., Begum, R., Smith, C., Taylor, S., McSorley, L., Alexopoulos, P., Moore, R., Kosicka-Slawinska, M., Ali, F.

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Quantifying prediction of pathogenicity for within-codon concordance (PM5) using 7541 functional classifications of BRCA1 and MSH2 missense variants von Loong, Lucy, Cubuk, Cankut, Garrett, Alice, Loveday, Chey, Durkie, Miranda, Wallace, Andrew, Eccles, Diana M., Tischkowitz, Marc, Ellard, Sian, Ware, James S., Turnbull, Clare, Ansari, A., Kumar, A., Donaldson, A., Brady, A., Hogg, A.-C., Bowden, A. Ramsay, Coad, B., Speight, B., DeSouza, B., Olimpio, C., Clabby, C., Byrne, C., Maurer, C., Baralle, D., Moore, D., Donnelly, D., Atkinson, E., Baple, E., Woodward, E., Petrides, E., McRonald, F., Pelz, F., Rea, G., Powell, H., Carley, H., Thomas, H.J.W., Cook, J., Hoyle, J., Murray, J., Field, J., Burn, J., Bruty, J., Grant, J., Barwell, J., Monahan, K., Tatton-Brown, K., Mokretar, K., Reay, K., Russell, K., Stone, K., Reed, L., Cobbold, L., Busby, L., Izatt, L., Side, L., Sarkies, L., Bartlett, M., Watson, M., Bradford, M., Huxley, M., Ryten, M., Roberts, N., O'Brien, C., Middleton, O., Tarpey, P., Logan, P., Dean, P., May, P., Brace, P., Tredwell, R., Hart, R., Martin, R., Nyanhete, R., Wright, R., Davidson, R., Talukdar, S., Butler, S., Ribeiro, S., Daniels, S., Abbs, S., Foo, T., Bedenham, T., Cranston, T., Woodwaer, N., Wallis, Y., Mullan, G., Reuther, A.-M., Lawn, C., Nocera-Jijon, D., Cross, E., Harper, J., Ciucias, K., Connolly, L., Tsang, M., Tadiso, T., Sahan, K., Worrillow, L., Barlett, M., Watt, C.

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A34 EFFECT OF AUTOPHAGY INDUCTION VIA TRPML1 ACTIVATION ON HEPATIC STEATOSIS von Tersigni, C, Capurro, M, MacParland, S A, Selzner-Malekkiani, N, Jones, N

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Hepatitis C Virus Persistence after Spontaneous or Treatment-Induced Resolution of Hepatitis C von PHAM, Tram N. Q, MACPARLAND, Sonya A, MULROONEY, Patricia M, COOKSLEY, Helen, NAOUMOV, Nikolai V, MICHALAK, Tomasz I

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A164 RAPID INTRAHEPATIC AND PERIPHERAL BLOOD HCV RNA DECLINE AND HCV-SPECIFIC IMMUNE RESPONSE INCREASE DURING IFN-FREE DAA THERAPY IN HCV TREATMENT-NAÏVE PATIENTS von MacParland, S A, Cherepanov, V, Vijgen, L, Gamil, M, Beumont, M, Yoon, S, Rahman, A, Capraru, C, Ostrowski, M A, Brahmania, M, Wong, D, Harrigan, R, Janssen, H L, Sulkowski, M S, Feld, J

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The Second Canadian Symposium on hepatitis C virus: a call to action von Grebely, Jason, Bilodeau, Marc, Feld, Jordan J, Bruneau, Julie, Fischer, Benedikt, Raven, Jennifer F, Roberts, Eve, Choucha, Norma, Myers, Rob P, Sagan, Selena M, Wilson, Joyce A, Bialystok, Frank, Tyrrell, D Lorne, Houghton, Michael, Krajden, Mel

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Mitogen-induced upregulation of hepatitis C virus expression in human lymphoid cells von Pham, Tram N. Q, MacParland, Sonya A, Coffin, Carla S, Lee, Samuel S, Bursey, Ford R, Michalak, Tomasz I

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Occult persistence of hepatitis C virus von Pham, TNQ, MacParland, SA, Michalak, TI

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Replication of infectious wild-type HCV in cultured human T cells von MacParland, SA, Pham, TNQ, Michalak, TI

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HCV specific IL-21 producing T cells but not IL-17A producing T cells are associated with HCV viral control in HIV/HCV coinfection von MacParland, SA, Fadel, SM, Mihajlovic, V, Fawaz, A, Kim, C, Nur-Ur Rahman, AKM, Liu, J, Kaul, R, Kovacs, C, Grebely, J, Dore, GJ, Wong, DK, Ostrowski, MA

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The 5th Canadian Symposium on Hepatitis C Virus: We Are Not Done Yet - Remaining Challenges in Hepatitis C von Van Buuren, N, Fradette, L, Grebely, J, King, A, Krajden, M, Macparland, SA, Marshall, A, Saeed, S, Wilson, J, Klein, MB, Sagan, SM

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The immune niche of the liver von Cheng, Michael L, Nakib, Diana, Perciani, Catia T, MacParland, Sonya A

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Single cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populations von MacParland, Sonya A., Liu, Jeff C., Ma, Xue-Zhong, Innes, Brendan T., Bartczak, Agata M., Gage, Blair K., Manuel, Justin, Khuu, Nicholas, Echeverri, Juan, Linares, Ivan, Gupta, Rahul, Cheng, Michael L., Liu, Lewis Y., Camat, Damra, Chung, Sai W., Seliga, Rebecca K., Shao, Zigong, Lee, Elizabeth, Ogawa, Shinichiro, Ogawa, Mina, Wilson, Michael D., Fish, Jason E., Selzner, Markus, Ghanekar, Anand, Grant, David, Greig, Paul, Sapisochin, Gonzalo, Selzner, Nazia, Winegarden, Neil, Adeyi, Oyedele, Keller, Gordon, Bader, Gary D., McGilvray, Ian D.

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Mechanism of hard-nanomaterial clearance by the liver von Tsoi, Kim M., MacParland, Sonya A., Ma, Xue-Zhong, Spetzler, Vinzent N., Echeverri, Juan, Ouyang, Ben, Fadel, Saleh M., Sykes, Edward A., Goldaracena, Nicolas, Kaths, Johann M., Conneely, John B., Alman, Benjamin A., Selzner, Markus, Ostrowski, Mario A., Adeyi, Oyedele A., Zilman, Anton, McGilvray, Ian D., Chan, Warren C. W.

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Generation of Functional Liver Sinusoidal Endothelial Cells from Human Pluripotent Stem-Cell-Derived Venous Angioblasts von Gage, Blair K., Liu, Jeff C., Innes, Brendan T., MacParland, Sonya A., McGilvray, Ian D., Bader, Gary D., Keller, Gordon M.

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