Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development von Wilensky, Robert L, Shi, Yi, Mohler, Emile R, Hamamdzic, Damir, Burgert, Mark E, Li, Jun, Postle, Anthony, Fenning, Robert S, Bollinger, James G, Hoffman, Bryan E, Pelchovitz, Daniel J, Yang, Jisheng, Mirabile, Rosanna C, Webb, Christine L, Zhang, LeFeng, Zhang, Ping, Gelb, Michael H, Walker, Max C, Zalewski, Andrew, Macphee, Colin H

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Pharmacological blockade of the mast cell MRGPRX2 receptor supports investigation of its relevance in skin disorders von Macphee, Colin H, Dong, Xinzhong, Peng, Qi, Paone, Daniel V, Skov, Per Stahl, Baumann, Katrine, Roethke, Theresa, Goldspink, Deborah A, Pearson, Samuel K, Wu, Zining

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Lipoprotein-associated phospholipase A2 and atherosclerosis von Wilensky, Robert L, Macphee, Colin H

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Discovery and Development of TMPRSS6 Inhibitors Modulating Hepcidin Levels in Human Hepatocytes von Béliveau, François, Tarkar, Aarti, Dion, Sébastien P., Désilets, Antoine, Ghinet, Mariana Gabriela, Boudreault, Pierre-Luc, St-Georges, Catherine, Marsault, Éric, Paone, Daniel, Collins, Jon, Macphee, Colin H., Campobasso, Nino, Groy, Arthur, Cottom, Josh, Ouellette, Michael, Pope, Andrew J., Leduc, Richard

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Pharmacological activation of liver X receptors promotes reverse cholesterol transport in vivo von NAIK, Snehal U, XUN WANG, DA SILVA, Jaqueline S, JAYE, Michael, MACPHEE, Colin H, REILLY, Muredach P, BILLHEIMER, Jeffrey T, ROTHBLAT, George H, RADER, Daniel J

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Effect of darapladib treatment on endarterectomy carotid plaque lipoprotein-associated phospholipase A2 activity: a randomized, controlled trial von Johnson, Joel L, Shi, Yi, Snipes, Rose, Janmohamed, Salim, Rolfe, Timothy E, Davis, Bill, Postle, Anthony, Macphee, Colin H

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The MRGPRX2-substance P pathway regulates mast cell migration von West, Peter W., Chéret, Jérémy, Bahri, Rajia, Kiss, Orsolya, Wu, Zining, Macphee, Colin H., Bulfone-Paus, Silvia

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Platelet aggregation unchanged by lipoprotein-associated phospholipase A₂ inhibition: results from an in vitro study and two randomized phase I trials von Shaddinger, Bonnie C, Xu, Yanmei, Roger, James H, Macphee, Colin H, Handel, Malcolm, Baidoo, Charlotte A, Magee, Mindy, Lepore, John J, Sprecher, Dennis L

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Electrospray Ionization Mass Spectrometry Identifies Substrates and Products of Lipoprotein-associated Phospholipase A2 in Oxidized Human Low Density Lipoprotein von Davis, Bill, Koster, Grielof, Douet, Lisa J., Scigelova, Michaela, Woffendin, Gary, Ward, Joanna M., Smith, Alberto, Humphries, Julia, Burnand, Kevin G., Macphee, Colin H., Postle, Anthony D.

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Lipoprotein-associated phospholipase A2 as a target of therapy von Macphee, Colin H, Nelson, Jeanenne J, Zalewski, Andrew

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Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase: a potential new risk factor for coronary artery disease von Caslake, Muriel J, Packard, Chris J, Suckling, Keith E, Holmes, Stephen D, Chamberlain, Paul, Macphee, Colin H

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Diabetes status modifies the long-term effect of lipoprotein-associated phospholipase A2 on major coronary events von Siddiqui, Moneeza K., Smith, Gillian, St Jean, Pamela, Dawed, Adem Y., Bell, Samira, Soto-Pedre, Enrique, Kennedy, Gwen, Carr, Fiona, Wallentin, Lars, White, Harvey, Macphee, Colin H., Waterworth, Dawn, Palmer, Colin N. A.

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Lipoprotein-associated phospholipase A(2) and atherosclerosis von Wilensky, Robert L, Macphee, Colin H

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Synthetic LXR agonists increase LDL in CETP species von Groot, Pieter H. E, Pearce, Nigel J, Yates, John W, Stocker, Claire, Sauermelch, Charles, Doe, Christopher P, Willette, Robert N, Olzinski, Alan, Peters, Tambra, d'Epagnier, Denise, Morasco, Kathleen O, Krawiec, John A, Webb, Christine L, Aravindhan, Karpagam, Jucker, Beat, Burgert, Mark, Ma, Chun, Marino, Joseph P, Collins, Jon L, Macphee, Colin H, Thompson, Scott K, Jaye, Michael

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Lipoprotein-Associated Phospholipase A2, Platelet-Activating Factor Acetylhydrolase, Is Expressed by Macrophages in Human and Rabbit Atherosclerotic Lesions von Häkkinen, Tomi, Luoma, Jukka S, Hiltunen, Mikko O, Macphee, Colin H, Milliner, Kevin J, Patel, Lisa, Rice, Simon Q, Tew, David G, Karkola, Kari, Ylä-Herttuala, NA

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Inhibition of lipoprotein-associated phospholipase [A.sub.2] reduces complex coronary atherosclerotic plaque development von Wilensky, Robert L, Shi, Yi, Mohler, III, Emile R, Hamamdzic, Damir, Burgert, Mark E, Li, Jun, Postle, Anthony, Fenning, Robert S, Bollinger, James G, Hoffman, Bryan E, Pelchovitz, Daniel J, Yang, Jisheng, Mirabile, Rosanna C, Webb, Christine L, Zhang, LeFeng, Zhang, Ping, Gelb, Michael H, Walker, Max C, Zalewski, Andrew, Macphee, Colin H

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Resistin is expressed in human macrophages and directly regulated by PPARγ activators von Patel, Lisa, Buckels, Amy C, Kinghorn, Ian J, Murdock, Paul R, Holbrook, Joanna D, Plumpton, Christopher, Macphee, Colin H, Smith, Stephen A

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Community-based statins and advanced carotid plaque: Role of CD163 positive macrophages in lipoprotein-associated phospholipase A2 activity in atherosclerotic plaque von Otsuka, Fumiyuki, Zhao, XiaoQing, Trout, Hugh H., Qiao, Ye, Wasserman, Bruce A., Nakano, Masataka, Macphee, Colin H., Brandt, Martin, Krug-Gourley, Sue, Guo, Liang, Ladich, Elena R., Cheng, Qi, Davis, Harry R., Finn, Aloke V., Virmani, Renu, Kolodgie, Frank D.

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Retinal pathology is associated with increased blood–retina barrier permeability in a diabetic and hypercholesterolaemic pig model: Beneficial effects of the LpPLA2 inhibitor Darap... von Acharya, Nimish K, Qi, Xin, Goldwaser, Eric L, Godsey, George A, Wu, Hao, Kosciuk, Mary C, Freeman, Theresa A, Macphee, Colin H, Wilensky, Robert L, Venkataraman, Venkat, Nagele, Robert G

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Discovery of Substituted Maleimides as Liver X Receptor Agonists and Determination of a Ligand-Bound Crystal Structure von Jaye, Michael C, Krawiec, John A, Campobasso, Nino, Smallwood, Angela, Qiu, Chunyan, Lu, Quinn, Kerrigan, John J, De Los Frailes Alvaro, Maite, Laffitte, Bryan, Liu, Wu-Schyong, Marino, Joseph P, Meyer, Craig R, Nichols, Jason A, Parks, Derek J, Perez, Paloma, Sarov-Blat, Lea, Seepersaud, Sheila D, Steplewski, Klaudia M, Thompson, Scott K, Wang, Ping, Watson, Mike A, Webb, Christine L, Haigh, David, Caravella, Justin A, Macphee, Colin H, Willson, Timothy M, Collins, Jon L

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