Fundamental Relationships between Structure, Reactivity, and Biological Activity for the Duocarmycins and CC-1065 von MacMillan, Karen S, Boger, Dale L

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Novel orexin receptor agonists based on arene- or pyridine-fused 1,3-dihydro-2H-imidazole-2-imines von Wang, Wentian, Ranjan, Alok, Zhang, Wei, Liang, Qiren, MacMillan, Karen S., Chapman, Karen, Wang, Xiaoyu, Chandrasekaran, Preethi, Williams, Noelle S., Rosenbaum, Daniel M., De Brabander, Jef K.

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Discovery of a Proneurogenic, Neuroprotective Chemical von Pieper, Andrew A., Xie, Shanhai, Capota, Emanuela, Estill, Sandi Jo, Zhong, Jeannie, Long, Jeffrey M., Becker, Ginger L., Huntington, Paula, Goldman, Shauna E., Shen, Ching-Han, Capota, Maria, Britt, Jeremiah K., Kotti, Tiina, Ure, Kerstin, Brat, Daniel J., Williams, Noelle S., MacMillan, Karen S., Naidoo, Jacinth, Melito, Lisa, Hsieh, Jenny, De Brabander, Jef, Ready, Joseph M., McKnight, Steven L.

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In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity von Brown, Craig S., Lee, Michael S., Leung, Daisy W., Wang, Tianjiao, Xu, Wei, Luthra, Priya, Anantpadma, Manu, Shabman, Reed S., Melito, Lisa M., MacMillan, Karen S., Borek, Dominika M., Otwinowski, Zbyszek, Ramanan, Parameshwaran, Stubbs, Alisha J., Peterson, Dayna S., Binning, Jennifer M., Tonelli, Marco, Olson, Mark A., Davey, Robert A., Ready, Joseph M., Basler, Christopher F., Amarasinghe, Gaya K.

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Development of Proneurogenic, Neuroprotective Small Molecules von MacMillan, Karen S, Naidoo, Jacinth, Liang, Jue, Melito, Lisa, Williams, Noelle S, Morlock, Lorraine, Huntington, Paula J, Estill, Sandi Jo, Longgood, Jamie, Becker, Ginger L, McKnight, Steven L, Pieper, Andrew A, De Brabander, Jef K, Ready, Joseph M

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Depression and Anxiety Disorders in Palliative Cancer Care von Wilson, Keith G., PhD, Chochinov, Harvey Max, MD, PhD, Graham Skirko, Merika, MSW, PhD, Allard, Pierre, MD, PhD, Chary, Srini, MD, Gagnon, Pierre R., MD, Macmillan, Karen, BScN, De Luca, Marina, MD, O'Shea, Fiona, MB, Kuhl, David, MD, PhD, Fainsinger, Robin L., MD, Clinch, Jennifer J., MA

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The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP-importin α interactions von Jung, Hunmin, Takeshima, Tomomi, Nakagawa, Tsutomu, MacMillan, Karen S, Wynn, R Max, Wang, Hanzhi, Sakiyama, Haruhiko, Wei, Shuguang, Li, Yang, Bruick, Richard K, Posner, Bruce A, De Brabander, Jef K, Uyeda, Kosaku

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Prognostic Acceptance and the Well-Being of Patients Receiving Palliative Care for Cancer von THOMPSON, Genevieve N, CHOCHINOV, Harvey M, WILSON, Keith G, MCPHERSON, Christine J, CHARY, Srini, O'SHEA, Fiona M, KUHL, David R, FAINSINGER, Robin L, GAGNON, Pierre R, MACMILLAN, Karen A

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Correction to “Total Synthesis and Evaluation of iso-Duocarmycin SA and iso-Yatakemycin” von MacMillan, Karen S, Nguyen, Trihn, Hwang, Inkyu, Boger, Dale L

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Total Synthesis and Evaluation of iso-Duocarmycin SA and iso-Yatakemycin von MacMillan, Karen S, Nguyen, Trihn, Hwang, Inkyu, Boger, Dale L

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Synthesis and evaluation of analogs of 5′-(((Z)-4-amino-2-butenyl)methylamino)-5′-deoxyadenosine (MDL 73811, or AbeAdo) – An inhibitor of S-adenosylmethionine decarboxylase with an... von Brockway, Anthony J., Volkov, Oleg A., Cosner, Casey C., MacMillan, Karen S., Wring, Stephen A., Richardson, Thomas E., Peel, Michael, Phillips, Margaret A., De Brabander, Jef K.

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Suffering With Advanced Cancer von Wilson, Keith G, Chochinov, Harvey Max, McPherson, Christine J, LeMay, Katerine, Allard, Pierre, Chary, Srini, Gagnon, Pierre R, Macmillan, Karen, De Luca, Marina, O'Shea, Fiona, Kuhl, David, Fainsinger, Robin L

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Desire for Euthanasia or Physician-Assisted Suicide in Palliative Cancer Care von Wilson, Keith G, Chochinov, Harvey Max, McPherson, Christine J, Graham Skirko, Merika, Allard, Pierre, Chary, Srini, Gagnon, Pierre R, Macmillan, Karen, De Luca, Marina, O'Shea, Fiona, Kuhl, David, Fainsinger, Robin L, Karam, Andrea M, Clinch, Jennifer J

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An Additional Spirocyclization for Duocarmycin SA von MacMillan, Karen S, Boger, Dale L

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Systematic Exploration of the Structural Features of Yatakemycin Impacting DNA Alkylation and Biological Activity von Tichenor, Mark S, MacMillan, Karen S, Trzupek, John D, Rayl, Thomas J, Hwang, Inkyu, Boger, Dale L

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Potent Cytotoxic C-11 Modified Geldanamycin Analogues von Tian, Zong-Qiang, Wang, Zhan, MacMillan, Karen S, Zhou, Yiqing, Carreras, Christopher W, Mueller, Thomas, Myles, David C, Liu, Yaoquan

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Rational Design, Synthesis, and Evaluation of Key Analogues of CC-1065 and the Duocarmycins von Tichenor, Mark S, MacMillan, Karen S, Stover, James S, Wolkenberg, Scott E, Pavani, Maria G, Zanella, Lorenzo, Zaid, Abdel N, Spalluto, Gianpiero, Rayl, Thomas J, Hwang, Inkyu, Baraldi, Pier Giovanni, Boger, Dale L

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Synthesis and preliminary evaluation of duocarmycin analogues incorporating the 1,2,11,11a-tetrahydrocyclopropa[ c]naphtho[2,3- e]indol-4-one (CNI) and 1,2,11,11a-tetrahydrocyclopr... von Gauss, Carla M., Hamasaki, Akiyuki, Parrish, Jay P., MacMillan, Karen S., Rayl, Thomas J., Hwang, Inkyu, Boger, Dale L.

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Synthesis and evaluation of duocarmycin SA analogs incorporating the methyl 1,2,8,8a-tetrahydrocyclopropa[ c]oxazolo[2,3- e]indol-4-one-6-carboxylate (COI) alkylation subunit von Boyle, Kristopher E., MacMillan, Karen S., Ellis, David A., Lajiness, James P., Robertson, William M., Boger, Dale L.

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Synthesis and evaluation of a thio analogue of duocarmycin SA von MacMillan, Karen S., Lajiness, James P., Cara, Carlota Lopez, Romagnoli, Romeo, Robertson, William M., Hwang, Inkyu, Baraldi, Pier Giovanni, Boger, Dale L.

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