Partial deletion of ROCK2 protects mice from high-fat diet-induced cardiac insulin resistance and contractile dysfunction von Soliman, Hesham, Nyamandi, Vongai, Garcia-Patino, Marysol, Varela, Julia Nogueira, Bankar, Girish, Lin, Guorong, Jia, Zhengping, MacLeod, Kathleen M

Volltext

Complex regulation of PKCβ2 and PDK-1/AKT by ROCK2 in diabetic heart von Lin, Guorong, Brownsey, Roger W, Macleod, Kathleen M

Volltext

Chronic etanercept treatment prevents the development of hypertension in fructose-fed rats von Tran, Linda T, MacLeod, Kathleen M, McNeill, John H

Volltext

Diabetes-induced increased oxidative stress in cardiomyocytes is sustained by a positive feedback loop involving Rho kinase and PKCβ2 von Soliman, Hesham, Gador, Anthony, Lu, Yi-Hsuan, Lin, Guorong, Bankar, Girish, MacLeod, Kathleen M

Volltext

GPCR agonist-induced transactivation of the EGFR upregulates MLC II expression and promotes hypertension in insulin-resistant rats von Nagareddy, Prabhakara Reddy, MacLeod, Kathleen M., McNeill, John H.

Volltext

Selective Inhibition of Protein Kinase C β2 Attenuates Inducible Nitric Oxide Synthase–Mediated Cardiovascular Abnormalities in Streptozotocin-Induced Diabetic Rats von REDDY NAGAREDDY, Prabhakara, SOLIMAN, Hesham, GUORONG LIN, RAJPUT, Padmesh S, KUMAR, Ujendra, MCNEILL, John H, MACLEOD, Kathleen M

Volltext

Chronic inhibition of inducible nitric oxide synthase ameliorates cardiovascular abnormalities in streptozotocin diabetic rats von Nagareddy, Prabhakara Reddy, McNeill, John H., MacLeod, Kathleen M.

Volltext

Role of inducible nitric oxide synthase in induction of RhoA expression in hearts from diabetic rats von Soliman, Hesham, Craig, Graham P., Nagareddy, Prabhakar, Yuen, Violet G., Lin, Guorong, Kumar, Ujendra, McNeill, John H., MacLeod, Kathleen M.

Volltext

ROCK2 as a novel target for diabetic cardiomyopathy von Soliman, Hesham, Nyamandi, Vongai, Hove-Madsen, Leif, MacLeod, Kathleen M.

Volltext

Excess Linoleic Acid Increases Collagen I/III Ratio and “Stiffens” the Heart Muscle Following High Fat Diets von Beam, Julianne, Botta, Amy, Ye, Jiayu, Soliman, Hesham, Matier, Brieanne J., Forrest, Mary, MacLeod, Kathleen M., Ghosh, Sanjoy

Volltext

ROCK2 promotes ryanodine receptor phosphorylation and arrhythmic calcium release in diabetic cardiomyocytes von Soliman, Hesham, Nyamandi, Vongai, Garcia-Patino, Marysol, Zhang, Ping-Cheng, Lin, Eric, Jia, Zheng Ping, Tibbits, Glen F., Hove-Madsen, Leif, MacLeod, Kathleen M.

Volltext

The ischemic metabolite lysophosphatidylcholine increases rat coronary arterial tone by endothelium-dependent mechanisms von Zhang, Rui, Bai, Ni, So, Jeremy, Laher, Ismail, MacLeod, Kathleen M, Rodrigues, Brian

Volltext

N-acetylcysteine Prevents Nitrosative Stress-Associated Depression of Blood Pressure and Heart Rate in Streptozotocin Diabetic Rats von Nagareddy, Prabhakara Reddy, Xia, Zhengyuan, MacLeod, Kathleen M, McNeill, John H

Volltext

Selective alpha(1)-adrenoceptor blockade prevents fructose-induced hypertension von Tran, Linda T, MacLeod, Kathleen M, McNeill, John H

Volltext

Increased expression of iNOS is associated with endothelial dysfunction and impaired pressor responsiveness in streptozotocin-induced diabetes von Nagareddy, Prabhakara Reddy, Xia, Zhengyuan, McNeill, John H, MacLeod, Kathleen M

Volltext

Contribution of Rho kinase to blood pressure elevation and vasoconstrictor responsiveness in type 2 diabetic Goto–Kakizaki rats von Rao, Milly Y, Soliman, Hesham, Bankar, Girish, Lin, Guorong, MacLeod, Kathleen M

Volltext

Acute inhibition of Rho-kinase improves cardiac contractile function in streptozotocin-diabetic rats von GUORONG LIN, CRAIG, Graham P, LILI ZHANG, YUEN, Violet G, ALLARD, Michael, MCNEILL, John H, MACLEOD, Kathleen M

Volltext

Maintenance of adrenergic vascular tone by MMP transactivation of the EGFR requires PI3K and mitochondrial ATP synthesis von Nagareddy, Prabhakara Reddy, Chow, Fung Lan, Hao, Li, Wang, Xiang, Nishimura, Tamiko, MacLeod, Kathleen M., McNeill, John H., Fernandez-Patron, Carlos

Volltext

Role of the PKC/CPI‐17 pathway in enhanced contractile responses of mesenteric arteries from diabetic rats to α‐adrenoceptor stimulation von Mueed, Irem, Zhang, Lili, MacLeod, Kathleen M

Volltext

Age-dependent changes in blood pressure and arterial reactivity in obese Zucker rats von Subramanian, Ramaswamy, MacLeod, Kathleen M.

Volltext