Structure of the murine CD94-NKG2A receptor in complex with Qa-1 b presenting an MHC-I leader peptide von MacLachlan, Bruce J, Sullivan, Lucy C, Brooks, Andrew G, Rossjohn, Jamie, Vivian, Julian P

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Structure of the murine CD94–NKG2A receptor in complex with Qa‐1b presenting an MHC‐I leader peptide von MacLachlan, Bruce J., Sullivan, Lucy C., Brooks, Andrew G., Rossjohn, Jamie, Vivian, Julian P.

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Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C von Moradi, Shoeib, Stankovic, Sanda, O’Connor, Geraldine M., Pymm, Phillip, MacLachlan, Bruce J., Faoro, Camilla, Retière, Christelle, Sullivan, Lucy C., Saunders, Philippa M., Widjaja, Jacqueline, Cox-Livingstone, Shea, Rossjohn, Jamie, Brooks, Andrew G., Vivian, Julian P.

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The Structural Basis for Recognition of Human Leukocyte Antigen Class I Molecules by the Pan-HLA Antibody W6/32 von Pymm, Phillip, Saunders, Philippa M, Anand, Sushma, MacLachlan, Bruce J, Faoro, Camilla, Hitchen, Corinne, Rossjohn, Jamie, Brooks, Andrew G, Vivian, Julian P

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Molecular characterization of HLA class II binding to the LAG‐3 T cell co‐inhibitory receptor von MacLachlan, Bruce J., Mason, Georgina H., Greenshields‐Watson, Alexander, Triebel, Frederic, Gallimore, Awen, Cole, David K., Godkin, Andrew

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Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity von Chen, Yuan, Mason, Georgina H., Scourfield, D. Oliver, Greenshields-Watson, Alexander, Haigh, Tracey A., Sewell, Andrew K., Long, Heather M., Gallimore, Awen M., Rizkallah, Pierre, MacLachlan, Bruce J., Godkin, Andrew

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The Role of the HLA Class I α2 Helix in Determining Ligand Hierarchy for the Killer Cell Ig-like Receptor 3DL1 von Saunders, Philippa M, MacLachlan, Bruce J, Widjaja, Jacqueline, Wong, Shu Cheng, Oates, Clare V L, Rossjohn, Jamie, Vivian, Julian P, Brooks, Andrew G

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A pocket guide on how to structure SARS-CoV-2 drugs and therapies von Littler, Dene R, MacLachlan, Bruce J, Watson, Gabrielle M, Vivian, Julian P, Gully, Benjamin S

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The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function von Saunders, Philippa M., MacLachlan, Bruce J., Pymm, Phillip, Illing, Patricia T., Deng, Yuanchen, Wong, Shu Cheng, Oates, Clare V. L., Purcell, Anthony W., Rossjohn, Jamie, Vivian, Julian P., Brooks, Andrew G.

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Seven mysteries of LAG-3: a multi-faceted immune receptor of increasing complexity von Burnell, Stephanie E A, Capitani, Lorenzo, MacLachlan, Bruce J, Mason, Georgina H, Gallimore, Awen M, Godkin, Andrew

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Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope von MacLachlan, Bruce J., Dolton, Garry, Papakyriakou, Athanasios, Greenshields-Watson, Alexander, Mason, Georgina H., Schauenburg, Andrea, Besneux, Matthieu, Szomolay, Barbara, Elliott, Tim, Sewell, Andrew K., Gallimore, Awen, Rizkallah, Pierre, Cole, David K., Godkin, Andrew

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CD4+ T Cells Recognize Conserved Influenza A Epitopes through Shared Patterns of V-Gene Usage and Complementary Biochemical Features von Greenshields-Watson, Alexander, Attaf, Meriem, MacLachlan, Bruce J., Whalley, Thomas, Rius, Cristina, Wall, Aaron, Lloyd, Angharad, Hughes, Hywel, Strange, Kathryn E., Mason, Georgina H., Schauenburg, Andrea J., Hulin-Curtis, Sarah L., Geary, James, Chen, Yuan, Lauder, Sarah N., Smart, Kathryn, Vijaykrishna, Dhanasekaran, Grau, Miguel L., Shugay, Mikhail, Andrews, Robert, Dolton, Garry, Rizkallah, Pierre J., Gallimore, Awen M., Sewell, Andrew K., Godkin, Andrew J., Cole, David K.

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A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation von Hulin-Curtis, Sarah, Geary, James K., MacLachlan, Bruce J., Altmann, Danny M., Baillon, Laury, Cole, David K., Greenshields-Watson, Alex, Hesketh, Sophie J., Humphreys, Ian R., Jones, Ian M., Lauder, Sarah N., Mason, Georgina H., Smart, Kathryn, Scourfield, D. Oliver, Scott, Jake, Sukhova, Ksenia, Stanton, Richard J., Wall, Aaron, Rizkallah, Pierre J., Barclay, Wendy S., Gallimore, Awen, Godkin, Andrew

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The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity: implications... von Besneux, Matthieu, Greenshields-Watson, Alexander, Scurr, Martin J., MacLachlan, Bruce J., Christian, Adam, Davies, Michael M., Hargest, Rachel, Phillips, Simon, Godkin, Andrew, Gallimore, Awen

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In Silico and Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility von Holland, Christopher J, MacLachlan, Bruce J, Bianchi, Valentina, Hesketh, Sophie J, Morgan, Richard, Vickery, Owen, Bulek, Anna M, Fuller, Anna, Godkin, Andrew, Sewell, Andrew K, Rizkallah, Pierre J, Wells, Stephen, Cole, David K

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Molecular Rules Underpinning Enhanced Affinity Binding of Human T Cell Receptors Engineered for Immunotherapy von Crean, Rory M., MacLachlan, Bruce J., Madura, Florian, Whalley, Thomas, Rizkallah, Pierre J., Holland, Christopher J., McMurran, Catriona, Harper, Stephen, Godkin, Andrew, Sewell, Andrew K., Pudney, Christopher R., van der Kamp, Marc W., Cole, David K.

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362 Allelic variants of MR1 drive cancer and allo-reactivity by MR1-restricted T cells von Howie, Duncan, Cornforth, Terri V, Moyo, Nathifa, Cole, Suzanne, Lam, Emily, Lobry, Tatiana, Wolchinsky, Ron, Lloyd, Angharad, Ward, Katarzyna, Denham, Eleanor M, Besra, Gurdyal S, Illing, Patricia, MacLachlan, Bruce, Vivian, Julian, Raynes, Jeremy, Nours, Jerome Le, Purcell, Anthony, Kundu, Samit, Silk, Jonathan D, Williams, Luke, Papa, Sophie, Rossjohn, Jamie, Dukes, Joseph

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Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens von MacLachlan, Bruce J, Greenshields-Watson, Alexander, Mason, Georgina H, Schauenburg, Andrea J, Bianchi, Valentina, Rizkallah, Pierre J, Sewell, Andrew K, Fuller, Anna, Cole, David K

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Unconventional modes of peptide-HLA-I presentation change the rules of TCR engagement von Hopkins, Jade R, MacLachlan, Bruce J, Harper, Stephen, Sewell, Andrew K, Cole, David K

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Structural definition of HLA class-II presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity" by Chen et al. 2023. Supplemental Information von Bruce MacLachlan

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