Modifying Caspase‑3 Activity by Altering Allosteric Networks von Cade, Christine, Swartz, Paul, MacKenzie, Sarah H., Clark, A. Clay

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Lengthening the Intersubunit Linker of Procaspase 3 Leads to Constitutive Activation von MacKenzie, Sarah H, Schipper, Joshua L, England, Erika J, Thomas, Melvin E, Blackburn, Kevin, Swartz, Paul, Clark, A. Clay

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A bifunctional allosteric site in the dimer interface of procaspase-3 von Schipper, Joshua L., MacKenzie, Sarah H., Sharma, Anil, Clark, A. Clay

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Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection von Maciag, Joseph J., Mackenzie, Sarah H., Tucker, Matthew B., Schipper, Joshua L., Swartz, Paul, Clark, A. Clay

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Slow Folding and Assembly of a Procaspase‑3 Interface Variant von MacKenzie, Sarah H, Clark, A. Clay

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Phage display and structural studies reveal plasticity in substrate specificity of caspase‐3a from zebrafish von Tucker, Matthew B., MacKenzie, Sarah H., Maciag, Joseph J., Dirscherl Ackerman, Hayley, Swartz, Paul, Yoder, Jeffrey A., Hamilton, Paul T., Clay Clark, A.

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Redesigning the procaspase‐8 dimer interface for improved dimerization von Ma, Chunxiao, MacKenzie, Sarah H., Clay Clark, A.

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A Tunable Allosteric Library of Caspase‐3 Identifies Coupling Between Conserved Water Molecules and Conformational Selection von Maciag, Joseph J., Mackenzie, Sarah H., Tucker, Matthew, Schipper, Joshua L., Swartz, Paul, Clark, A. Clay

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Phage Display and Structural Studies Reveal Plasticity in Substrate Specificity and Allosteric Regulation of Caspase‐3 from Zebrafish von Clark, Clay, Tucker, Matthew B, MacKenzie, Sarah H., Maciag, Joseph J, Dirscherl, Hayley B, Swartz, Paul B, Yoder, Jeffrey B, Hamilton, Paul B

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A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19 von Boulware, David R, Pullen, Matthew F, Bangdiwala, Ananta S, Pastick, Katelyn A, Lofgren, Sarah M, Okafor, Elizabeth C, Skipper, Caleb P, Nascene, Alanna A, Nicol, Melanie R, Abassi, Mahsa, Engen, Nicole W, Cheng, Matthew P, LaBar, Derek, Lother, Sylvain A, MacKenzie, Lauren J, Drobot, Glen, Marten, Nicole, Zarychanski, Ryan, Kelly, Lauren E, Schwartz, Ilan S, McDonald, Emily G, Rajasingham, Radha, Lee, Todd C, Hullsiek, Kathy H

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High-Frequency Oscillation for Acute Respiratory Distress Syndrome von Young, Duncan, Lamb, Sarah E, Shah, Sanjoy, MacKenzie, Iain, Tunnicliffe, William, Lall, Ranjit, Rowan, Kathy, Cuthbertson, Brian H

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Epigenetic Control of Mitochondrial Fission Enables Self-Renewal of Stem-like Tumor Cells in Human Prostate Cancer von Civenni, Gianluca, Bosotti, Roberto, Timpanaro, Andrea, Vàzquez, Ramiro, Merulla, Jessica, Pandit, Shusil, Rossi, Simona, Albino, Domenico, Allegrini, Sara, Mitra, Abhishek, Mapelli, Sarah N., Vierling, Luca, Giurdanella, Martina, Marchetti, Martina, Paganoni, Alyssa, Rinaldi, Andrea, Losa, Marco, Mira-Catò, Enrica, D'Antuono, Rocco, Morone, Diego, Rezai, Keyvan, D'Ambrosio, Gioacchino, Ouafik, L’Houcine, Mackenzie, Sarah, Riveiro, Maria E., Cvitkovic, Esteban, Carbone, Giuseppina M., Catapano, Carlo V.

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Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase von Takahashi, Hideyuki, Bhagwagar, Sanaea, Nies, Sarah H., Ye, Hongping, Han, Xianlin, Chiasseu, Marius T., Wang, Guilin, Mackenzie, Ian R., Strittmatter, Stephen M.

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Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers von Kumar, Akash, White, Thomas A, MacKenzie, Alexandra P, Clegg, Nigel, Lee, Choli, Dumpit, Ruth F, Coleman, Ilsa, Ng, Sarah B, Salipante, Stephen J, Rieder, Mark J, Nickerson, Deborah A, Corey, Eva, Lange, Paul H, Morrissey, Colm, Vessella, Robert L, Nelson, Peter S, Shendure, Jay

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A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis von Flum, David R, Davidson, Giana H, Monsell, Sarah E, Shapiro, Nathan I, Odom, Stephen R, Sanchez, Sabrina E, Drake, F Thurston, Fischkoff, Katherine, Johnson, Jeffrey, Patton, Joe H, Evans, Heather, Cuschieri, Joseph, Sabbatini, Amber K, Faine, Brett A, Skeete, Dionne A, Liang, Mike K, Sohn, Vance, McGrane, Karen, Kutcher, Matthew E, Chung, Bruce, Carter, Damien W, Ayoung-Chee, Patricia, Chiang, William, Rushing, Amy, Steinberg, Steven, Foster, Careen S, Schaetzel, Shaina M, Price, Thea P, Mandell, Katherine A, Ferrigno, Lisa, Salzberg, Matthew, DeUgarte, Daniel A, Kaji, Amy H, Moran, Gregory J, Saltzman, Darin, Alam, Hasan B, Park, Pauline K, Kao, Lillian S, Thompson, Callie M, Self, Wesley H, Yu, Julianna T, Wiebusch, Abigail, Winchell, Robert J, Clark, Sunday, Krishnadasan, Anusha, Fannon, Erin, Lavallee, Danielle C, Comstock, Bryan A, Bizzell, Bonnie, Heagerty, Patrick J, Kessler, Larry G, Talan, David A

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Memory regulatory T cells reside in human skin von Sanchez Rodriguez, Robert, Pauli, Mariela L, Neuhaus, Isaac M, Yu, Siegrid S, Arron, Sarah T, Harris, Hobart W, Yang, Sara Hsin-Yi, Anthony, Bryan A, Sverdrup, Francis M, Krow-Lucal, Elisabeth, MacKenzie, Tippi C, Johnson, David S, Meyer, Everett H, Löhr, Andrea, Hsu, Andro, Koo, John, Liao, Wilson, Gupta, Rishu, Debbaneh, Maya G, Butler, Daniel, Huynh, Monica, Levin, Ethan C, Leon, Argentina, Hoffman, William Y, McGrath, Mary H, Alvarado, Michael D, Ludwig, Connor H, Truong, Hong-An, Maurano, Megan M, Gratz, Iris K, Abbas, Abul K, Rosenblum, Michael D

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Listening to Yourself and Watching Your Tongue: Distinct Abilities and Brain Regions for Monitoring Semantic and Phonological Speech Errors von McCall, Joshua D., DeMarco, Andrew T., Mandal, Ayan S., Fama, Mackenzie E., van der Stelt, Candace M., Lacey, Elizabeth H., Laks, Alycia B., Snider, Sarah F., Friedman, Rhonda B., Turkeltaub, Peter E.

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Bridging the Gap: A Practical Approach to Discussing eGFR and Race with Medical Students von Holmberg, Mackenzie H, Çoruh, Başak, Sanghavi, Sarah F

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DnaJ/Hsc70 chaperone complexes control the extracellular release of neurodegenerative-associated proteins von Fontaine, Sarah N, Zheng, Dali, Sabbagh, Jonathan J, Martin, Mackenzie D, Chaput, Dale, Darling, April, Trotter, Justin H, Stothert, Andrew R, Nordhues, Bryce A, Lussier, April, Baker, Jeremy, Shelton, Lindsey, Kahn, Mahnoor, Blair, Laura J, Stevens Jr, Stanley M, Dickey, Chad A

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How directed evolution reshapes the energy landscape in an enzyme to boost catalysis von Otten, Renee, Pádua, Ricardo A P, Bunzel, H Adrian, Nguyen, Vy, Pitsawong, Warintra, Patterson, MacKenzie, Sui, Shuo, Perry, Sarah L, Cohen, Aina E, Hilvert, Donald, Kern, Dorothee

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