Discovery of Benzothiazole Scaffold-Based DNA Gyrase B Inhibitors von Gjorgjieva, Marina, Tomašič, Tihomir, Barančokova, Michaela, Katsamakas, Sotirios, Ilaš, Janez, Tammela, Päivi, Peterlin Mašič, Lucija, Kikelj, Danijel

Volltext

Overcoming challenges of HERG potassium channel liability through rational design: Eag1 inhibitors for cancer treatment von Toplak, Žan, Hendrickx, Louise A., Abdelaziz, Reham, Shi, Xiaoyi, Peigneur, Steve, Tomašič, Tihomir, Tytgat, Jan, Peterlin‐Mašič, Lucija, Pardo, Luis A.

Volltext

Discovery of 4,5,6,7-Tetrahydrobenzo[1,2‑d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site von Tomašič, Tihomir, Katsamakas, Sotirios, Hodnik, Žiga, Ilaš, Janez, Brvar, Matjaž, Solmajer, Tom, Montalvão, Sofia, Tammela, Päivi, Banjanac, Mihailo, Ergović, Gabrijela, Anderluh, Marko, Mašič, Lucija Peterlin, Kikelj, Danijel

Volltext

Computer-aided structure-based optimization of 4,5,6,7-tetrahydrobenzo[]thiazole-2,6-diamine derivatives as DNA gyrase B inhibitors von Gutierrez, Lucas J, Vettorazzi, Marcela, Dernovšek, Jaka, Durcik, Martina, Maši, Lucija Peterlin, Tomaši, Tihomir, Enriz, Ricardo D

Volltext

Discovery of KV1.3 ion channel inhibitors: Medicinal chemistry approaches and challenges von Gubič, Špela, Hendrickx, Louise A., Toplak, Žan, Sterle, Maša, Peigneur, Steve, Tomašič, Tihomir, Pardo, Luis A., Tytgat, Jan, Zega, Anamarija, Mašič, Lucija P.

Volltext

Benzothiazole DNA gyrase inhibitors and their conjugates with siderophore mimics: design, synthesis and evaluation von Durcik, Martina, Cruz, Cristina D, Scorciapino, Mariano Andrea, Ilaš, Janez, Tammela, Päivi, Ceccarelli, Matteo, Maši, Lucija Peterlin, Tomaši, Tihomir

Volltext

N‑Phenyl-4,5-dibromopyrrolamides and N‑Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation von Zidar, Nace, Macut, Helena, Tomašič, Tihomir, Brvar, Matjaž, Montalvão, Sofia, Tammela, Päivi, Solmajer, Tom, Peterlin Mašič, Lucija, Ilaš, Janez, Kikelj, Danijel

Volltext

Rational design of balanced dual-targeting antibiotics with limited resistance von Nyerges, Akos, Tomašič, Tihomir, Durcik, Martina, Revesz, Tamas, Szili, Petra, Draskovits, Gabor, Bogar, Ferenc, Skok, Žiga, Zidar, Nace, Ilaš, Janez, Zega, Anamarija, Kikelj, Danijel, Daruka, Lejla, Kintses, Balint, Vasarhelyi, Balint, Foldesi, Imre, Kata, Diána, Welin, Martin, Kimbung, Raymond, Focht, Dorota, Mašič, Lucija Peterlin, Pal, Csaba

Volltext

Discovery of Novel 5-Benzylidenerhodanine and 5-Benzylidenethiazolidine-2,4-dione Inhibitors of MurD Ligase von Zidar, Nace, Tomašić, Tihomir, Šink, Roman, Rupnik, Veronika, Kovač, Andreja, Turk, Samo, Patin, Delphine, Blanot, Didier, Contreras Martel, Carlos, Dessen, Andréa, Müller Premru, Manica, Zega, Anamarija, Gobec, Stanislav, Peterlin Mašič, Lucija, Kikelj, Danijel

Volltext

Synthesis, Antiproliferative Effect, and Topoisomerase II Inhibitory Activity of 3‑Methyl-2-phenyl‑1H‑indoles von Zidar, Nace, Secci, Daniela, Tomašič, Tihomir, Mašič, Lucija Peterlin, Kikelj, Danijel, Passarella, Daniele, Argaez, Aida Nelly Garcia, Hyeraci, Mariafrancesca, Dalla Via, Lisa

Volltext

New N -phenylpyrrolamide inhibitors of DNA gyrase with improved antibacterial activity von Cotman, Andrej Emanuel, Fulgheri, Federica, Piga, Martina, Peršolja, Peter, Tiz, Davide Benedetto, Skok, Žiga, Durcik, Martina, Sterle, Maša, Dernovšek, Jaka, Cruz, Cristina D, Tammela, Päivi, Szili, Petra Éva, Daruka, Lejla, Pál, Csaba, Zega, Anamarija, Mašič, Lucija Peterlin, Ilaš, Janez, Tomašič, Tihomir, Kikelj, Danijel, Zidar, Nace

Volltext

Bioactivation Potential of Thiophene-Containing Drugs von Gramec, Darja, Peterlin Mašič, Lucija, Sollner Dolenc, Marija

Volltext

Bioactivation of bisphenol A and its analogs (BPF, BPAF, BPZ and DMBPA) in human liver microsomes von Schmidt, Jan, Kotnik, Petra, Trontelj, Jurij, Knez, Željko, Mašič, Lucija Peterlin

Volltext

Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity von Gubič, Špela, Hendrickx, Louise, Shi, Xiaoyi, Toplak, Žan, Možina, Štefan, Theemsche, Kenny, Pinheiro-Junior, Ernesto, Peigneur, Steve, Labro, Alain, Pardo, Luis, Tytgat, Jan, Tomašič, Tihomir, Mašič, Lucija

Volltext

Antimicrobial activity of the marine alkaloids, clathrodin and oroidin, and their synthetic analogues von Zidar, Nace, Montalvão, Sofia, Hodnik, Žiga, Nawrot, Dorota A, Žula, Aleš, Ilaš, Janez, Kikelj, Danijel, Tammela, Päivi, Mašič, Lucija Peterlin

Volltext

Efflux pump inhibitors of clinically relevant multidrug resistant bacteria von Lamut, Andraž, Peterlin Mašič, Lucija, Kikelj, Danijel, Tomašič, Tihomir

Volltext

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold-Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa von Cotman, Andrej Emanuel, Durcik, Martina, Benedetto Tiz, Davide, Fulgheri, Federica, Secci, Daniela, Sterle, Maša, Možina, Štefan, Skok, Žiga, Zidar, Nace, Zega, Anamarija, Ilaš, Janez, Peterlin Mašič, Lucija, Tomašič, Tihomir, Hughes, Diarmaid, Huseby, Douglas L., Cao, Sha, Garoff, Linnéa, Berruga Fernández, Talía, Giachou, Paraskevi, Crone, Lisa, Simoff, Ivailo, Svensson, Richard, Birnir, Bryndis, Korol, Sergiy V., Jin, Zhe, Vicente, Francisca, Ramos, Maria C., de la Cruz, Mercedes, Glinghammar, Björn, Lenhammar, Lena, Henderson, Sara R., Mundy, Julia E. A., Maxwell, Anthony, Stevenson, Clare E. M., Lawson, David M., Janssen, Guido V., Sterk, Geert Jan, Kikelj, Danijel

Volltext

New Dual Inhibitors of Bacterial Topoisomerases with Broad-Spectrum Antibacterial Activity and In Vivo Efficacy against Vancomycin-Intermediate Staphylococcus aureus von Durcik, Martina, Cotman, Andrej Emanuel, Toplak, Žan, Možina, Štefan, Skok, Žiga, Szili, Petra Eva, Czikkely, Márton, Maharramov, Elvin, Vu, Thu Hien, Piras, Maria Vittoria, Zidar, Nace, Ilaš, Janez, Zega, Anamarija, Trontelj, Jurij, Pardo, Luis A., Hughes, Diarmaid, Huseby, Douglas, Berruga-Fernández, Tália, Cao, Sha, Simoff, Ivailo, Svensson, Richard, Korol, Sergiy V., Jin, Zhe, Vicente, Francisca, Ramos, Maria C., Mundy, Julia E. A., Maxwell, Anthony, Stevenson, Clare E. M., Lawson, David M., Glinghammar, Björn, Sjöström, Eva, Bohlin, Martin, Oreskär, Joanna, Alvér, Sofie, Janssen, Guido V., Sterk, Geert Jan, Kikelj, Danijel, Pal, Csaba, Tomašič, Tihomir, Peterlin Mašič, Lucija

Volltext

Exploring the Chemical Space of Benzothiazole-Based DNA Gyrase B Inhibitors von Skok, Žiga, Barančoková, Michaela, Benek, Ondřej, Cruz, Cristina Durante, Tammela, Päivi, Tomašič, Tihomir, Zidar, Nace, Mašič, Lucija Peterlin, Zega, Anamarija, Stevenson, Clare E. M, Mundy, Julia E. A, Lawson, David M, Maxwell, Anthony, Kikelj, Danijel, Ilaš, Janez

Volltext

Bisphenol A and its analogs: Do their metabolites have endocrine activity? von GramecSkledar, Darja, Peterlin Mašič, Lucija

Volltext