Enhanced Properties of a Benzimidazole Benzylpyrazole Lysine Demethylase Inhibitor: Mechanism-of-Action, Binding Site Analysis, and Activity in Cellular Models of Prostate Cancer von Carter, David M, Specker, Edgar, Małecki, Piotr H, Przygodda, Jessica, Dudaniec, Krystyna, Weiss, Manfred S, Heinemann, Udo, Nazaré, Marc, Gohlke, Ulrich

Volltext

Structure-based mapping of the histone-binding pocket of KDM4D using functionalized tetrazole and pyridine core compounds von Małecki, Piotr H., Fassauer, Georg M., Rüger, Nicole, Schulig, Lukas, Link, Andreas, Krylova, Oxana, Heinemann, Udo, Weiss, Manfred S.

Volltext

Structural Characterization of Glycerol Kinase from the Thermophilic Fungus Chaetomium thermophilum von Wilk, Piotr, Kuśka, Katarzyna, Wątor, Elżbieta, Małecki, Piotr H, Woś, Klaudia, Tokarz, Piotr, Dubin, Grzegorz, Grudnik, Przemysław

Volltext

Structure‐Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases von Małecki, Piotr H., Rüger, Nicole, Roatsch, Martin, Krylova, Oxana, Link, Andreas, Jung, Manfred, Heinemann, Udo, Weiss, Manfred S.

Volltext

Binding of the plant hormone kinetin in the active site of Mistletoe Lectin I from Viscum album von Małecki, Piotr H., Rypniewski, Wojciech, Szymański, Maciej, Barciszewski, Jan, Meyer, Arne

Volltext

The Crystal Structure of a Streptomyces thermoviolaceus Thermophilic Chitinase Known for Its Refolding Efficiency von Malecki, Piotr H, Bejger, Magdalena, Rypniewski, Wojciech, Vorgias, Constantinos E

Volltext

A Helminth-Derived Chitinase Structurally Similar to Mammalian Chitinase Displays Immunomodulatory Properties in Inflammatory Lung Disease von Ebner, Friederike, Lindner, Katja, Janek, Katharina, Niewienda, Agathe, Malecki, Piotr H., Weiss, Manfred S., Sutherland, Tara E., Heuser, Arnd, Kühl, Anja A., Zentek, Jürgen, Hofmann, Andreas, Hartmann, Susanne

Volltext

A closer look at molecular mechanisms underlying inhibition of S -adenosyl-L-homocysteine hydrolase by transition metal cations von Gawel, Magdalena, Malecki, Piotr H, Sliwiak, Joanna, Stepniewska, Marlena, Imiolczyk, Barbara, Czyrko-Horczak, Justyna, Jakubczyk, Dorota, Marczak, Łukasz, Plonska-Brzezinska, Marta Eliza, Brzezinski, Krzysztof

Volltext

Biochemical and structural insights into an unusual, alkali‐metal‐independent S‐adenosyl‐l‐homocysteine hydrolase from Synechocystis sp. PCC 6803 von Malecki, Piotr H., Imiolczyk, Barbara, Barciszewski, Jakub, Czyrko-Horczak, Justyna, Sliwiak, Joanna, Gawel, Magdalena, Wozniak, Katarzyna, Jaskolski, Mariusz, Brzezinski, Krzysztof

Volltext

Crystal structures of substrate-bound chitinase from the psychrophilic bacterium Moritella marina and its structure in solution von Malecki, Piotr H., Vorgias, Constantinos E., Petoukhov, Maxim V., Svergun, Dmitri I., Rypniewski, Wojciech

Volltext

Front Cover: Structure‐Based Screening of Tetrazolylhydrazide Inhibitors versus KDM4 Histone Demethylases (ChemMedChem 21/2019) von Małecki, Piotr H., Rüger, Nicole, Roatsch, Martin, Krylova, Oxana, Link, Andreas, Jung, Manfred, Heinemann, Udo, Weiss, Manfred S.

Volltext

Structure of a complete four-domain chitinase from Moritella marina, a marine psychrophilic bacterium von Malecki, Piotr H., Raczynska, Joanna E., Vorgias, Constantinos E., Rypniewski, Wojciech

Volltext

The stability of the TIM-barrel domain of a psychrophilic chitinase von Stavros, Philemon, Malecki, Piotr H, Theodoridou, Maria, Rypniewski, Wojciech, Vorgias, Constantinos E, Nounesis, George

Volltext

A closer look at molecular mechanisms underlying inhibition of -adenosyl--homocysteine hydrolase by transition metal cations von Gawel, Magdalena, Malecki, Piotr H, Sliwiak, Joanna, Stepniewska, Marlena, Imiolczyk, Barbara, Czyrko-Horczak, Justyna, Jakubczyk, Dorota, Marczak, ukasz, Plonska-Brzezinska, Marta Eliza, Brzezinski, Krzysztof

Volltext

Survival in extremes von H. Malecki, Piotr, Rypniewski, Wojciech

Volltext

Variants influencing age at diagnosis of HNF1A-MODY von Ludwig-Słomczyńska, Agnieszka H, Seweryn, Michał T, Radkowski, Piotr, Kapusta, Przemysław, Machlowska, Julita, Pruhova, Stepanka, Gasperikova, Daniela, Bellanne-Chantelot, Christine, Hattersley, Andrew, Kandasamy, Balamurugan, Letourneau-Freiberg, Lisa, Philipson, Louis, Doria, Alessandro, Wołkow, Paweł P, Małecki, Maciej T, Klupa, Tomasz

Volltext

A family with the Arg103Pro mutation in the NEUROD1 gene detected by next-generation sequencing – Clinical characteristics of mutation carriers von Szopa, Magdalena, Ludwig-Galezowska, Agnieszka H, Radkowski, Piotr, Skupien, Jan, Machlowska, Julita, Klupa, Tomasz, Wolkow, Pawel, Borowiec, Maciej, Mlynarski, Wojciech, Malecki, Maciej T

Volltext

Qualitative Parameters of the Colonic Flora in Patients with HNF1A-MODY Are Different from Those Observed in Type 2 Diabetes Mellitus von Matejko, Bartlomiej, Salamon, Dominika, Malecki, Maciej T., Wolkow, Pawel, Klupa, Tomasz, Sroka-Oleksiak, Agnieszka, Morawska, Iwona, Ludwig-Galezowska, Agnieszka H., Bulanda, Małgorzata, Szopa, Magdalena, Gosiewski, Tomasz, Radkowski, Piotr, Mrozinska, Sandra, Kapusta, Przemyslaw

Volltext

Up-regulation of human PNPase mRNA by beta-interferon has no effect on protein level in melanoma cell lines von Gewartowski, Kamil, Tomecki, Rafal, Muchowski, Lukasz, Dmochow Ska, Aleksandra, Dzwonek, Artur, Malecki, Michal, Skurzak, Henryk, Ostrowski, Jerzy, Stepien, Piotr P

Volltext

Additional file 1 of Variants influencing age at diagnosis of HNF1A-MODY von Ludwig-Słomczyńska, Agnieszka H., Seweryn, Michał T., Radkowski, Piotr, Kapusta, Przemysław, Machlowska, Julita, Pruhova, Stepanka, Gasperikova, Daniela, Bellanne-Chantelot, Christine, Hattersley, Andrew, Kandasamy, Balamurugan, Letourneau-Freiberg, Lisa, Philipson, Louis, Doria, Alessandro, Wołkow, Paweł P., Małecki, Maciej T., Klupa, Tomasz

Volltext bestellen