Autophagy Assays for Biological Discovery and Therapeutic Development von Mizushima, Noboru, Murphy, Leon O.

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TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1 von Dibble, Christian C., Elis, Winfried, Menon, Suchithra, Qin, Wei, Klekota, Justin, Asara, John M., Finan, Peter M., Kwiatkowski, David J., Murphy, Leon O., Manning, Brendan D.

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Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation von Wlodarska, Marta, Luo, Chengwei, Kolde, Raivo, d’Hennezel, Eva, Annand, John W., Heim, Cortney E., Krastel, Philipp, Schmitt, Esther K., Omar, Abdifatah S., Creasey, Elizabeth A., Garner, Ashley L., Mohammadi, Sina, O’Connell, Daniel J., Abubucker, Sahar, Arthur, Timothy D., Franzosa, Eric A., Huttenhower, Curtis, Murphy, Leon O., Haiser, Henry J., Vlamakis, Hera, Porter, Jeffrey A., Xavier, Ramnik J.

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Total Lipopolysaccharide from the Human Gut Microbiome Silences Toll-Like Receptor Signaling von d'Hennezel, Eva, Abubucker, Sahar, Murphy, Leon O, Cullen, Thomas W

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Potential therapeutic applications of autophagy von Rubinsztein, David C, Gestwicki, Jason E, Murphy, Leon O, Klionsky, Daniel J

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Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy von Eng, Christina H., Wang, Zuncai, Tkach, Diane, Toral-Barza, Lourdes, Ugwonali, Savuth, Liu, Shanming, Fitzgerald, Stephanie L., George, Elizabeth, Frias, Elizabeth, Cochran, Nadire, De Jesus, Rowena, McAllister, Gregory, Hoffman, Gregory R., Bray, Kevin, Lemon, LuAnna, Lucas, Judy, Fantin, Valeria R., Abraham, Robert T., Murphy, Leon O., Nyfeler, Beat

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Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9 von Goodwin, Jonathan M., Dowdle, William E., DeJesus, Rowena, Wang, Zuncai, Bergman, Philip, Kobylarz, Marek, Lindeman, Alicia, Xavier, Ramnik J., McAllister, Gregory, Nyfeler, Beat, Hoffman, Gregory, Murphy, Leon O.

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Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1 von Düvel, Katrin, Yecies, Jessica L., Menon, Suchithra, Raman, Pichai, Lipovsky, Alex I., Souza, Amanda L., Triantafellow, Ellen, Ma, Qicheng, Gorski, Regina, Cleaver, Stephen, Vander Heiden, Matthew G., MacKeigan, Jeffrey P., Finan, Peter M., Clish, Clary B., Murphy, Leon O., Manning, Brendan D.

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Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy von Nicklin, Paul, Bergman, Philip, Zhang, Bailin, Triantafellow, Ellen, Wang, Henry, Nyfeler, Beat, Yang, Haidi, Hild, Marc, Kung, Charles, Wilson, Christopher, Myer, Vic E., MacKeigan, Jeffrey P., Porter, Jeffrey A., Wang, Y. Karen, Cantley, Lewis C., Finan, Peter M., Murphy, Leon O.

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Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance von Blenis, John, MacKeigan, Jeffrey P, Murphy, Leon O

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A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages von Bedard, Melissa, van der Niet, Sanne, Bernard, Elliott M, Babunovic, Gregory, Cheng, Tan-Yun, Aylan, Beren, Grootemaat, Anita E, Raman, Sahadevan, Botella, Laure, Ishikawa, Eri, O'Sullivan, Mary P, O'Leary, Seónadh, Mayfield, Jacob A, Buter, Jeffrey, Minnaard, Adriaan J, Fortune, Sarah M, Murphy, Leon O, Ory, Daniel S, Keane, Joseph, Yamasaki, Sho, Gutierrez, Maximiliano G, van der Wel, Nicole, Moody, D Branch

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Vps34 PI 3-kinase inactivation enhances insulin sensitivity through reprogramming of mitochondrial metabolism von Bilanges, Benoit, Alliouachene, Samira, Pearce, Wayne, Morelli, Daniele, Szabadkai, Gyorgy, Chung, Yuen-Li, Chicanne, Gaëtan, Valet, Colin, Hill, Julia M., Voshol, Peter J., Collinson, Lucy, Peddie, Christopher, Ali, Khaled, Ghazaly, Essam, Rajeeve, Vinothini, Trichas, Georgios, Srinivas, Shankar, Chaussade, Claire, Salamon, Rachel S., Backer, Jonathan M., Scudamore, Cheryl L., Whitehead, Maria A., Keaney, Erin P., Murphy, Leon O., Semple, Robert K., Payrastre, Bernard, Tooze, Sharon A., Vanhaesebroeck, Bart

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Functional CRISPR screening identifies the ufmylation pathway as a regulator of SQSTM1/p62 von DeJesus, Rowena, Moretti, Francesca, McAllister, Gregory, Wang, Zuncai, Bergman, Phil, Liu, Shanming, Frias, Elizabeth, Alford, John, Reece-Hoyes, John S, Lindeman, Alicia, Kelliher, Jennifer, Russ, Carsten, Knehr, Judith, Carbone, Walter, Beibel, Martin, Roma, Guglielmo, Ng, Aylwin, Tallarico, John A, Porter, Jeffery A, Xavier, Ramnik J, Mickanin, Craig, Murphy, Leon O, Hoffman, Gregory R, Nyfeler, Beat

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Molecular interpretation of ERK signal duration by immediate early gene products von Blenis, John, Murphy, Leon O, Smith, Sallie, Chen, Rey-Huei, Fingar, Diane C

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A Network of Immediate Early Gene Products Propagates Subtle Differences in Mitogen-Activated Protein Kinase Signal Amplitude and Duration von Murphy, Leon O., MacKeigan, Jeffrey P., Blenis, John

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Relieving Autophagy and 4EBP1 from Rapamycin Resistance von Nyfeler, Beat, Bergman, Philip, Triantafellow, Ellen, Wilson, Christopher J., Zhu, Yanyi, Radetich, Branko, Finan, Peter M., Klionsky, Daniel J., Murphy, Leon O.

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An iron-dependent metabolic vulnerability underlies VPS34-dependence in RKO cancer cells von Kobylarz, Marek J, Goodwin, Jonathan M, Kang, Zhao B, Annand, John W, Hevi, Sarah, O'Mahony, Ellen, McAllister, Gregory, Reece-Hoyes, John, Wang, Qiong, Alford, John, Russ, Carsten, Lindeman, Alicia, Beibel, Martin, Roma, Guglielmo, Carbone, Walter, Knehr, Judith, Loureiro, Joseph, Antczak, Christophe, Wiederschain, Dmitri, Murphy, Leon O, Menon, Suchithra, Nyfeler, Beat

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Defective Autophagy and mTORC1 Signaling in Myotubularin Null Mice von Fetalvero, Kristina M., Yu, Yenyen, Goetschkes, Margaret, Liang, Guiqing, Valdez, Reginald A., Gould, Ty, Triantafellow, Ellen, Bergling, Sebastian, Loureiro, Joseph, Eash, John, Lin, Victor, Porter, Jeffrey A., Finan, Peter M., Walsh, Kenneth, Yang, Yi, Mao, Xiaohong, Murphy, Leon O.

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MAPK signal specificity: the right place at the right time von Murphy, Leon O., Blenis, John

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Atg4b-dependent autophagic flux alleviates Huntington's disease progression von Proenca, Catia C, Stoehr, Natacha, Bernhard, Mario, Seger, Shanon, Genoud, Christel, Roscic, Ana, Paganetti, Paolo, Liu, Shanming, Murphy, Leon O, Kuhn, Rainer, Bouwmeester, Tewis, Galimberti, Ivan

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