Modulating biomolecular condensates: a novel approach to drug discovery von Mitrea, Diana M., Mittasch, Matthäus, Gomes, Beatriz Ferreira, Klein, Isaac A., Murcko, Mark A.

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What Makes a Great Medicinal Chemist? A Personal Perspective von Murcko, Mark A

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Structure is beauty, but not always truth von Fraser, James S., Murcko, Mark A.

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What Do Medicinal Chemists Actually Make? A 50-Year Retrospective von Walters, W. Patrick, Green, Jeremy, Weiss, Jonathan R, Murcko, Mark A

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What Makes a Great Medicinal Chemist? A Personal Perspective: Miniperspective von Murcko, Mark A

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Accurate and Reliable Prediction of Relative Ligand Binding Potency in Prospective Drug Discovery by Way of a Modern Free-Energy Calculation Protocol and Force Field von Wang, Lingle, Wu, Yujie, Deng, Yuqing, Kim, Byungchan, Pierce, Levi, Krilov, Goran, Lupyan, Dmitry, Robinson, Shaughnessy, Dahlgren, Markus K, Greenwood, Jeremy, Romero, Donna L, Masse, Craig, Knight, Jennifer L, Steinbrecher, Thomas, Beuming, Thijs, Damm, Wolfgang, Harder, Ed, Sherman, Woody, Brewer, Mark, Wester, Ron, Murcko, Mark, Frye, Leah, Farid, Ramy, Lin, Teng, Mobley, David L, Jorgensen, William L, Berne, Bruce J, Friesner, Richard A, Abel, Robert

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Preclinical activity of VX-787, a first-in-class, orally bioavailable inhibitor of the influenza virus polymerase PB2 subunit von Byrn, Randal A, Jones, Steven M, Bennett, Hamilton B, Bral, Chris, Clark, Michael P, Jacobs, Marc D, Kwong, Ann D, Ledeboer, Mark W, Leeman, Joshua R, McNeil, Colleen F, Murcko, Mark A, Nezami, Azin, Perola, Emanuele, Rijnbrand, Rene, Saxena, Kumkum, Tsai, Alice W, Zhou, Yi, Charifson, Paul S

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Principles and functions of condensate modifying drugs von Patel, Avinash, Mitrea, Diana, Namasivayam, Vigneshwaran, Murcko, Mark A, Wagner, Michael, Klein, Isaac A

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The Properties of Known Drugs. 1. Molecular Frameworks von Bemis, Guy W, Murcko, Mark A

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Can We Learn To Distinguish between “Drug-like” and “Nondrug-like” Molecules? von Ajay, Walters, W. Patrick, Murcko, Mark A

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Prediction of ‘drug-likeness’ von Walters, W.Patrick, Murcko, Mark A

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Kinase-likeness and Kinase-Privileged Fragments: Toward Virtual Polypharmacology von Aronov, Alex M, McClain, Brian, Moody, Cameron Stuver, Murcko, Mark A

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Consensus Scoring:  A Method for Obtaining Improved Hit Rates from Docking Databases of Three-Dimensional Structures into Proteins von Charifson, Paul S, Corkery, Joseph J, Murcko, Mark A, Walters, W. Patrick

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Computational Methods to Predict Binding Free Energy in Ligand-Receptor Complexes von Murcko, Mark A

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Recognizing molecules with drug-like properties von Walters, W Patrick, Murcko, Ajay A, Murcko, Mark A

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Properties of Known Drugs. 2. Side Chains von Bemis, Guy W, Murcko, Mark A

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Designing Libraries with CNS Activity von Ajay, Bemis, Guy W, Murcko, Mark A

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Virtual screening : an overview von WALTERS, W. P, STAHL, M. T, MURCKO, M. A

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Assessing the impact of generative AI on medicinal chemistry von Walters, W. Patrick, Murcko, Mark

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Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding von Kim, Joseph L, Morgenstern, Kurt A, Griffith, James P, Dwyer, Maureen D, Thomson, John A, Murcko, Mark A, Lin, Chao, Caron, Paul R

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