A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors von Menon, Malini, Elliott, Richard, Bowers, Leandra, Balan, Nicolae, Rafiq, Rumana, Costa-Cabral, Sara, Munkonge, Felix, Trinidade, Ines, Porter, Roderick, Campbell, Andrew D., Johnson, Emma R., Esdar, Christina, Buchstaller, Hans-Peter, Leuthner, Birgitta, Rohdich, Felix, Schneider, Richard, Sansom, Owen, Wienke, Dirk, Ashworth, Alan, Lord, Christopher J.

Volltext

CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression von Hyde, Stephen C, Pringle, Ian A, Abdullah, Syahril, Lawton, Anna E, Davies, Lee A, Varathalingam, Anusha, Nunez-Alonso, Graciela, Green, Anne-Marie, Bazzani, Reto P, Sumner-Jones, Stephanie G, Chan, Mario, Li, Hongyu, Yew, Nelson S, Cheng, Seng H, Christopher Boyd, A, Davies, Jane C, Griesenbach, Uta, Porteous, David J, Sheppard, David N, Munkonge, Felix M, Alton, Eric W F W, Gill, Deborah R

Volltext

Identification of Protein Cofactors Necessary for Sequence-specific Plasmid DNA Nuclear Import von Miller, Aaron M, Munkonge, Felix M, Alton, Eric WFW, Dean, David A

Volltext

Identification and Functional Characterization of Cytoplasmic Determinants of Plasmid DNA Nuclear Import von Munkonge, Felix M., Amin, Vaksha, Hyde, Stephen C., Green, Anne-Marie, Pringle, Ian A., Gill, Deborah R., Smith, Joel W.S., Hooley, Robert P., Xenariou, Stefania, Ward, Malcolm A., Leeds, Nicola, Leung, Kit-Yi, Chan, Mario, Hillery, Elizabeth, Geddes, Duncan M., Griesenbach, Uta, Postel, Edith H., Dean, David A., Dunn, Michael J., Alton, Eric W.F.W.

Volltext

Emerging significance of plasmid DNA nuclear import in gene therapy von Munkonge, Felix M., Dean, David A., Hillery, Elizabeth, Griesenbach, Uta, Alton, Eric W.F.W.

Volltext

The use of carboxymethylcellulose gel to increase non-viral gene transfer in mouse airways von Griesenbach, Uta, Meng, Cuixiang, Farley, Raymond, Wasowicz, Marguerite Y, Munkonge, Felix M, Chan, Mario, Stoneham, Charlotte, Sumner-Jones, Stephanie G, Pringle, Ian A, Gill, Deborah R, Hyde, Stephen C, Stevenson, Barbara, Holder, Emma, Ban, Hiroshi, Hasegawa, Mamoru, Cheng, Seng H, Scheule, Ronald K, Sinn, Patrick L, McCray, Paul B, Alton, Eric W.F.W

Volltext

The efficacy of a ‘master switch gene’ HIF-1α in a porcine model of chronic myocardial ischaemia von Heinl-Green, Amanda, Radke, Peter W., Munkonge, Felix M., Frass, Oliver, Zhu, Jie, Vincent, Karen, Geddes, Duncan M., Alton, Eric W.F.W.

Volltext

Assessment of the nuclear pore dilating agent trans-cyclohexane-1,2-diol in differentiated airway epithelium von Griesenbach, Uta, Wilson, Katherine M., Farley, Raymond, Meng, Cuixiang, Munkonge, Felix M., Cheng, Seng H., Scheule, Ronald K., Alton, Eric W. F. W.

Volltext

Limitations of the murine nose in the development of nonviral airway gene transfer von Griesenbach, Uta, Sumner-Jones, Stephanie G, Holder, Emma, Munkonge, Felix M, Wodehouse, Theresa, Smith, Stephen N, Wasowicz, Marguerite Y, Pringle, Ian, Casamayor, Isabel, Chan, Mario, Coles, Rebecca, Cornish, Nikki, Dewar, Ann, Doherty, Ann, Farley, Raymond, Green, Anne-Marie, Jones, Bryony L, Larsen, Mia D B, Lawton, Anna E, Manvell, Michelle, Painter, Hazel, Singh, Charanjit, Somerton, Lucinda, Stevenson, Barbara, Varathalingam, Anusha, Siegel, Craig, Scheule, Ronald K, Cheng, Seng H, Davies, Jane C, Porteous, David J, Gill, Deborah R, Boyd, A Christopher, Hyde, Steve C, Alton, Eric W F W

Volltext

Assessment of CFTR Function after Gene Transfer In Vitro and In Vivo von Griesenbach, Uta, Munkonge, Felix M., Sumner-Jones, Stephanie, Holder, Emma, Smith, Stephen N., Boyd, A. Christopher, Gill, Deborah R., Hyde, Stephen C., Porteous, David, Alton, Eric W.F.W.

Volltext

Nondisruptive, sequence-specific coupling of fluorochromes to plasmid DNA von Hillery, Elizabeth, Munkonge, Felix M., Xenariou, Stefania, Dean, David A., Alton, Eric W.F.W.

Volltext

Toward Gene Therapy for Cystic Fibrosis Using a Lentivirus Pseudotyped With Sendai Virus Envelopes von Mitomo, Katsuyuki, Griesenbach, Uta, Inoue, Makoto, Somerton, Lucinda, Meng, Cuixiang, Akiba, Eiji, Tabata, Toshiaki, Ueda, Yasuji, Frankel, Gad M, Farley, Raymond, Singh, Charanjit, Chan, Mario, Munkonge, Felix, Brum, Andrea, Xenariou, Stefania, Escudero-Garcia, Sara, Hasegawa, Mamoru, Alton, Eric WFW

Volltext

Asthma prophylaxis agents alter the function of an airway epithelial chloride channel von Alton, EW, Kingsleigh-Smith, DJ, Munkonge, FM, Smith, SN, Lindsay, AR, Gruenert, DC, Jeffery, PK, Norris, A, Geddes, DM, Williams, AJ

Volltext

Design and discovery of 3-aryl-5-substituted-isoquinolin-1-ones as potent tankyrase inhibitors von Elliott, Richard J. R., Jarvis, Ashley, Rajasekaran, Mohan B., Menon, Malini, Bowers, Leandra, Boffey, Ray, Bayford, Melanie, Firth-Clark, Stuart, Key, Rebekah, Aqil, Rehan, Kirton, Stewart B., Niculescu-Duvaz, Dan, Fish, Laura, Lopes, Filipa, McLeary, Robert, Trindade, Ines, Vendrell, Elisenda, Munkonge, Felix, Porter, Rod, Perrior, Trevor, Springer, Caroline, Oliver, Antony W., Pearl, Laurence H., Ashworth, Alan, Lord, Christopher J.

Volltext

Adenovirus-mediated In Utero Expression of CFTR Does Not Improve Survival of CFTR Knockout Mice von Davies, Lee A, Varathalingam, Anusha, Painter, Hazel, Lawton, Anna E, Sumner-Jones, Stephanie G, Nunez-Alonso, Graciela A, Chan, Mario, Munkonge, Felix, Alton, Eric WFW, Hyde, Stephen C, Gill, Deborah R

Volltext

Design and discovery of 3-aryl-5-substituted-isoquinolin-1-ones as potent tankyrase inhibitorsElectronic supplementary information (ESI) available: For complete experimental detail... von Elliott, Richard J. R, Jarvis, Ashley, Rajasekaran, Mohan B, Menon, Malini, Bowers, Leandra, Boffey, Ray, Bayford, Melanie, Firth-Clark, Stuart, Key, Rebekah, Aqil, Rehan, Kirton, Stewart B, Niculescu-Duvaz, Dan, Fish, Laura, Lopes, Filipa, McLeary, Robert, Trindade, Ines, Vendrell, Elisenda, Munkonge, Felix, Porter, Rod, Perrior, Trevor, Springer, Caroline, Oliver, Antony W, Pearl, Laurence H, Ashworth, Alan, Lord, Christopher J

Volltext

Methods of reconstitution of the purified sarcoplasmic reticulum (Ca 2+Mg 2+)-ATPase using bile salt detergents to form membranes of defined lipid to protein ratios or sealed vesi... von Michelangeli, Francesco, Munkonge, Felix M.

Volltext

Measurement of halide efflux from cultured and primary airway epithelial cells using fluorescence indicators von Munkonge, Felix, Alton, Eric W.F.W., Andersson, Charlotte, Davidson, Heather, Dragomir, Anca, Edelman, Aleksander, Farley, Ray, Hjelte, Lena, McLachlan, Gerry, Stern, Myra, Roomans, Godfried M.

Volltext

The efficacy of a 'master switch gene' HIF-1[alpha] in a porcine model of chronic myocardial ischaemia von Heinl-Green, Amanda, Radke, Peter W, Munkonge, Felix M, Frass, Oliver, Zhu, Jie, Vincent, Karen, Geddes, Duncan M, Eric W.F.W. Alton

Volltext

The efficacy of a 'master switch gene' HIF-1alpha in a porcine model of chronic myocardial ischaemia von Heinl-Green, Amanda, Radke, Peter W, Munkonge, Felix M, Frass, Oliver, Zhu, Jie, Vincent, Karen, Geddes, Duncan M, Alton, Eric W F W

Volltext