High-purity preparation of HSV-2 vaccine candidate ACAM529 is immunogenic and efficacious in vivo von Mundle, Sophia T, Hernandez, Hector, Hamberger, John, Catalan, John, Zhou, Changhong, Stegalkina, Svetlana, Tiffany, Andrea, Kleanthous, Harry, Delagrave, Simon, Anderson, Stephen F

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Mapping of a Novel H3-Specific Broadly Neutralizing Monoclonal Antibody Targeting the Hemagglutinin Globular Head Isolated from an Elite Influenza Virus-Immunized Donor Exhibiting... von Qiu, Yu, Stegalkina, Svetlana, Zhang, Jianxin, Boudanova, Ekaterina, Park, Anna, Zhou, Yanfeng, Prabakaran, Ponraj, Pougatcheva, Svetlana, Ustyugova, Irina, Vogel, Thorsten U., Mundle, Sophia T., Oomen, Ray, Delagrave, Simon, Ross, Ted M., Kleanthous, Harry, Qiu, Huawei

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Impact of age and pre-existing influenza immune responses in humans receiving split inactivated influenza vaccine on the induction of the breadth of antibodies to influenza A strai... von Nuñez, Ivette A, Carlock, Michael A, Allen, James D, Owino, Simon O, Moehling, Krissy K, Nowalk, Patricia, Susick, Michael, Diagle, Kensington, Sweeney, Kristen, Mundle, Sophia, Vogel, Thorsten U, Delagrave, Simon, Ramgopal, Moti, Zimmerman, Richard K, Kleanthous, Harry, Ross, Ted M

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Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus von Rush, Scott A., Brar, Gurpreet, Hsieh, Ching-Lin, Chautard, Emilie, Rainho-Tomko, Jennifer N., Slade, Chris D., Bricault, Christine A., Kume, Ana, Kearns, James, Groppo, Rachel, Mundle, Sophia T., Zhang, Linong, Casimiro, Danilo, Fu, Tong-Ming, DiNapoli, Joshua M., McLellan, Jason S.

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Influenza vaccination in the elderly boosts antibodies against conserved viral proteins and egg-produced glycans von Jung, Jiwon, Mundle, Sophia T., Ustyugova, Irina, Horton, Andrew P., Boutz, Daniel R., Pougatcheva, Svetlana, Prabakaran, Ponraj, McDaniel, Jonathan R., King, Gregory R., Park, Daechan, Person, Maria D., Ye, Congxi, Tan, Bing, Tanno, Yuri, Kim, Jin Eyun, Curtis, Nicholas C., DiNapoli, Joshua, Delagrave, Simon, Ross, Ted M., Ippolito, Gregory C., Kleanthous, Harry, Lee, Jiwon, Georgiou, George

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Immunogenicity and efficacy of intramuscular replication-defective and subunit vaccines against herpes simplex virus type 2 in the mouse genital model von Delagrave, Simon, Hernandez, Hector, Zhou, Changhong, Hamberger, John F, Mundle, Sophia T, Catalan, John, Baloglu, Simge, Anderson, Stephen F, DiNapoli, Joshua M, Londoño-Hayes, Patricia, Parrington, Mark, Almond, Jeffrey, Kleanthous, Harry

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Core bead chromatography for preparation of highly pure, infectious respiratory syncytial virus in the negative purification mode von Mundle, Sophia T, Kishko, Michael, Groppo, Rachel, DiNapoli, Joshua, Hamberger, John, McNeil, Bryan, Kleanthous, Harry, Parrington, Mark, Zhang, Linong, Anderson, Stephen F

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Development of multivalent mRNA vaccine candidates for seasonal or pandemic influenza von Chivukula, Sudha, Plitnik, Timothy, Tibbitts, Timothy, Karve, Shrirang, Dias, Anusha, Zhang, Donghui, Goldman, Rebecca, Gopani, Hardip, Khanmohammed, Asad, Sarode, Ashish, Cooper, Dustin, Yoon, Heesik, Kim, Younghoon, Yan, Yanhua, Mundle, Sophia T., Groppo, Rachel, Beauvais, Adrien, Zhang, Jinrong, Anosova, Natalie G., Lai, Charles, Li, Lu, Ulinski, Gregory, Piepenhagen, Peter, DiNapoli, Joshua, Kalnin, Kirill V., Landolfi, Victoria, Swearingen, Ron, Fu, Tong-Ming, DeRosa, Frank, Casimiro, Danilo

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Immunogenicity and protective efficacy of RSV G central conserved domain vaccine with a prefusion nanoparticle von Rainho-Tomko, Jennifer N., Pavot, Vincent, Kishko, Michael, Swanson, Kurt, Edwards, Darin, Yoon, Heesik, Lanza, Lilibeth, Alamares-Sapuay, Judith, Osei-Bonsu, Robert, Mundle, Sophia T., Murison, Dave A., Gallichan, Scott, Delagrave, Simon, Wei, Chih-Jen, Zhang, Linong, Nabel, Gary J.

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Preparation of pure, high titer, pseudoinfectious Flavivirus particles by hollow fiber tangential flow filtration and anion exchange chromatography von Mundle, Sophia T, Giel-Moloney, Maryann, Kleanthous, Harry, Pugachev, Konstantin V, Anderson, Stephen F

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Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of Clostridium difficile toxin B von Liu, Jinyu, Kothe, Michael, Zhang, Jianxin, Oloo, Eliud, Stegalkina, Svetlana, Mundle, Sophia T., Li, Lu, Zhang, Jinrong, Cole, Leah E., Barone, Lucianna, Biemann, Hans-Peter, Kleanthous, Harry, Anosova, Natalie G., Anderson, Stephen F.

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Enzymatic Mechanism of Human Apurinic/Apyrimidinic Endonuclease against a THF AP Site Model Substrate von Mundle, Sophia T, Delaney, James C, Essigmann, John M, Strauss, Phyllis R

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Novel role of tyrosine in catalysis by human AP endonuclease 1 von Mundle, Sophia T., Fattal, Michael H., Melo, Luisa F., Coriolan, Jean D., O’Regan, N. Edel, Strauss, Phyllis R.

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Role of active site tyrosines in dynamic aspects of DNA binding by AP endonuclease von Melo, Luisa F., Mundle, Sophia T., Fattal, Michael H., O’Regan, N. Edel, Strauss, Phyllis R.

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Deciphering the domain specificity of C. difficile toxin neutralizing antibodies von Cole, Leah E., Li, Lu, Jetley, Utsav, Zhang, Jinrong, Pacheco, Kristl, Ma, Fuqin, Zhang, Jianxin, Mundle, Sophia, Yan, Yanhua, Barone, Lucianna, Rogers, Christopher, Beltraminelli, Nicola, Quemeneur, Laurence, Kleanthous, Harry, Anderson, Stephen F., Anosova, Natalie G.

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Increasing Domain Coverage Improves Neutralizing Potency of C. difficile Toxin-specific Antibodies von Li, Lu, Cole, Leah E., Jetley, Utsav, Zhang, Jinrong, Pacheco, Kristl, Ma, Fuqin, Zhang, Jianxin, Mundle, Sophia, Yan, Yanhua, Barone, Lucianna, Rogers, Christopher, Beltraminelli, Nicola, Quemeneur, Laurence, Kleanthous, Harry, Anderson, Stephen F., Anosova, Natalie G.

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A Combination of Three Fully Human Toxin A- and Toxin B-Specific Monoclonal Antibodies Protects against Challenge with Highly Virulent Epidemic Strains of Clostridium difficile in... von Anosova, Natalie G, Cole, Leah E, Li, Lu, Zhang, Jinrong, Brown, Anna M, Mundle, Sophia, Zhang, Jianxin, Ray, Satyajit, Ma, Fuqin, Garrone, Pierre, Bertraminelli, Nicola, Kleanthous, Harry, Anderson, Stephen F

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Pre-existing Fc profiles shape the evolution of neutralizing antibody breadth following influenza vaccination von Boudreau, Carolyn M., Burke, John S., Roederer, Alexander L., Gorman, Matthew J., Mundle, Sophia, Lingwood, Daniel, Delagrave, Simon, Sridhar, Saranya, Ross, Ted M., Kleanthous, Harry, Alter, Galit

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Comparison of parenteral delivery routes of ACAM529, a replication-defective vaccine against genital herpes (106.24) von Hernandez, Hector, Zhou, Changhong, Mundle, Sophia, Hamberger, John, Catalan, John, Pougatcheva, Svetlana, Anderson, Stephen, Londono-Hayes, Patricia, Kleantous, Harold, Delagrave, Simon

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Enzymatic mechanism of human apurinic/apyrimidinic endonuclease against a THF AP site model substrate von Mundle, Sophia T, Delaney, James C, Essigman, John M, Strauss, Phyllis R

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