AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3 von Wunderlich, M, Chou, F-S, Link, K A, Mizukawa, B, Perry, R L, Carroll, M, Mulloy, J C

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Rac1 GTPase: A “Rac” of All Trades von Bosco, E. E, Mulloy, J. C, Zheng, Y

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Posttranslational modifications of RUNX1 as potential anticancer targets von Goyama, S, Huang, G, Kurokawa, M, Mulloy, J C

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CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors von Negrotto, S, Ng, K P, Jankowska, A M, Bodo, J, Gopalan, B, Guinta, K, Mulloy, J C, Hsi, E, Maciejewski, J, Saunthararajah, Y

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Protease-activated receptor-1 inhibits proliferation but enhances leukemia stem cell activity in acute myeloid leukemia von Goyama, S, Shrestha, M, Schibler, J, Rosenfeldt, L, Miller, W, O’Brien, E, Mizukawa, B, Kitamura, T, Palumbo, J S, Mulloy, J C

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p53 Independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia von Ng, K P, Ebrahem, Q, Negrotto, S, Mahfouz, R Z, Link, K A, Hu, Z, Gu, X, Advani, A, Kalaycio, M, Sobecks, R, Sekeres, M, Copelan, E, Radivoyevitch, T, Maciejewski, J, Mulloy, J C, Saunthararajah, Y

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An MDS xenograft model utilizing a patient-derived cell line von Rhyasen, G W, Wunderlich, M, Tohyama, K, Garcia-Manero, G, Mulloy, J C, Starczynowski, D T

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Chromatin modifications induced by the AML1-ETO fusion protein reversibly silence its genomic targets through AML1 and Sp1 binding motifs von Maiques-Diaz, A, Chou, F S, Wunderlich, M, Gómez-López, G, Jacinto, F V, Rodriguez-Perales, S, Larrayoz, M J, Calasanz, M J, Mulloy, J C, Cigudosa, J C, Alvarez, S

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UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO von Goyama, S, Schibler, J, Gasilina, A, Shrestha, M, Lin, S, Link, K A, Chen, J, Whitman, S P, Bloomfield, C D, Nicolet, D, Assi, S A, Ptasinska, A, Heidenreich, O, Bonifer, C, Kitamura, T, Nassar, N N, Mulloy, J C

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Human T-Cell Lymphotropic/Leukemia Virus Type 1 Tax Abrogates p53-Induced Cell Cycle Arrest and Apoptosis through Its CREB/ATF Functional Domain von Mulloy, J C, Kislyakova, T, Cereseto, A, Casareto, L, LoMonico, A, Fullen, J, Lorenzi, M V, Cara, A, Nicot, C, Giam, C, Franchini, G

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Constitutively Activated Jak-STAT Pathway in T Cells Transformed with HTLV-I von Migone, Thi-Sau, Lin, Jian-Xin, Cereseto, Anna, Mulloy, James C., O'Shea, John J., Franchini, Genoveffa, Leonard, Warren J.

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Free major histocompatibility complex class I heavy chain is preferentially targeted for degradation by human T-cell leukemia/lymphotropic virus type 1 p12(I) protein von Johnson, J M, Nicot, C, Fullen, J, Ciminale, V, Casareto, L, Mulloy, J C, Jacobson, S, Franchini, G

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Phosphatase PRL2 promotes AML1-ETO-induced acute myeloid leukemia von Kobayashi, M, Chen, S, Bai, Y, Yao, C, Gao, R, Sun, X-J, Mu, C, Twiggs, T A, Yu, Z-H, Boswell, H S, Yoder, M C, Kapur, R, Mulloy, J C, Zhang, Z-Y, Liu, Y

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Proliferation of Adult T Cell Leukemia/Lymphoma Cells is Associated with the Constitutive Activation of JAK/STAT Proteins von Takemoto, Shigeki, Mulloy, James C., Cereseto, Anna, Migone, Thi-Sao, Barvin K. R. Patel, Matsuoka, Masao, Yamaguchi, Kuzunari, Takatsuki, Kiyoshi, Kamihira, Shimeru, White, Jeffrey D., Leonard, Warren J., Waldmann, Thomas, Franchini, Genoveffa

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The MHC class I heavy chain is a common target of the small proteins encoded by the 3' end of HTLV type 1 and HTLV type 2 von JOHNSON, Julie M, MULLOY, James C, CIMINALE, Vincenzo, FULLEN, Jake, NICOT, Christophe, FRANCHINI, Genoveffa

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AML1-ETO Fusion Protein up-Regulates TRKA mRNA Expression in Human CD34+Cells, Allowing Nerve Growth Factor-Induced Expansion von Mulloy, James C., Jankovic, Vladimir, Wunderlich, Mark, Delwel, Ruud, Cammenga, Jorg, Krejci, Ondrej, Zhao, Hui, Peter J. M. Valk, Lowenberg, Bob, Nimer, Stephen D., Rowley, Janet D.

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HTLV-1 p12(I) protein enhances STAT5 activation and decreases the interleukin-2 requirement for proliferation of primary human peripheral blood mononuclear cells von Nicot, C, Mulloy, J C, Ferrari, M G, Johnson, J M, Fu, K, Fukumoto, R, Trovato, R, Fullen, J, Leonard, W J, Franchini, G

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Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia von Wei, Junping, Wunderlich, Mark, Fox, Catherine, Alvarez, Sara, Cigudosa, Juan C., Wilhelm, Jamie S., Zheng, Yi, Cancelas, Jose A., Gu, Yi, Jansen, Michael, DiMartino, Jorge F., Mulloy, James C.

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Cyclic nucleotide phosphodiesterases (PDE) 3 and 4 in normal, malignant, and HTLV-I transformed human lymphocytes von Ekholm, Dag, Mulloy, James C, Gao, Guang, Degerman, Eva, Franchini, Genoveffa, Manganiello, Vincent C

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A lysine-to-arginine change found in natural alleles of the human T-cell lymphotropic/leukemia virus type 1 p12(I) protein greatly influences its stability von Trovato, R, Mulloy, J C, Johnson, J M, Takemoto, S, de Oliveira, M P, Franchini, G

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