Therapeutic Potential of Poly(ADP-ribose) Polymerase Inhibitor AG014699 in Human Cancers With Mutated or Methylated BRCA1 or BRCA2 von DREW, Yvette, MULLIGAN, Evan A, EDMONDSON, Richard J, CURTIN, Nicola J, VONG, Wan-Tse, THOMAS, Huw D, KAHN, Samra, KYLE, Suzanne, MUKHOPADHYAY, Asima, LOS, Gerrit, HOSTOMSKY, Zdenek, PLUMMER, Elizabeth R

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6-Thioguanine Selectively Kills BRCA2-Defective Tumors and Overcomes PARP Inhibitor Resistance von ISSAEVA, Natalia, THOMAS, Huw D, CHATZAKOS, Vicky, MULLIGAN, Evan A, LUNDIN, Cecilia, GUBANOVA, Evgenia, KERSBERGEN, Ariena, HARRIS, Adrian L, SHARMA, Ricky A, ROTTENBERG, Sven, CURTIN, Nicola J, HELLEDAY, Thomas, DJURENOVIC, Tatjana, JASPERS, Janneke E, STOIMENOV, Ivaylo, KYLE, Suzanne, PEDLEY, Nicholas, GOTTIPATI, Ponnari, ZUR, Rafal, SLEETH, Kate

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Expression and Activity of the NF-κB Subunits in Chronic Lymphocytic Leukaemia: A Role for RelB and Non-Canonical Signalling von Mulligan, Evan A, Tudhope, Susan J, Hunter, Jill E, Clift, Arabella E. G, Elliott, Sarah L, Summerfield, Geoffrey P, Wallis, Jonathan, Pepper, Chris J, Durkacz, Barabara, Veuger, Stephany, Willmore, Elaine

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Effective sensitization of temozolomide by ABT-888 is lost with development of temozolomide resistance in glioblastoma xenograft lines von Clarke, Michelle J, Mulligan, Evan A, Grogan, Patrick T, Mladek, Ann C, Carlson, Brett L, Schroeder, Mark A, Curtin, Nicola J, Lou, Zhenkun, Decker, Paul A, Wu, Wenting, Plummer, E Ruth, Sarkaria, Jann N

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Inhibition of Poly(ADP-Ribose) Polymerase-1 Enhances Temozolomide and Topotecan Activity against Childhood Neuroblastoma von DANIEL, Rachel A, ROZANSKA, Agata L, CURTIN, Nicola J, CLIFFORD, Steven C, THOMAS, Huw D, MULLIGAN, Evan A, DREW, Yvette, CASTELBUONO, Deborah J, HOSTOMSKY, Zdenek, PLUMMER, E. Ruth, BODDY, Alan V, TWEDDLE, Deborah A

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PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia von Herriott, Ashleigh, Tudhope, Susan J, Junge, Gesa, Rodrigues, Natalie, Patterson, Miranda J, Woodhouse, Laura, Lunec, John, Hunter, Jill E, Mulligan, Evan A, Cole, Michael, Allinson, Lisa M, Wallis, Jonathan P, Marshall, Scott, Wang, Evelyn, Curtin, Nicola J, Willmore, Elaine

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High-Throughput Screen for Inhibitors of Klebsiella pneumoniae Virulence Using a Tetrahymena pyriformis Co-Culture Surrogate Host Model von Woods, Angela L, Parker, David, Glick, Meir M, Peng, Yunshan, Lenoir, Francois, Mulligan, Evan, Yu, Vincent, Piizzi, Grazia, Lister, Troy, Lilly, Maria-Dawn, Dzink-Fox, JoAnn, Jansen, Johanna M, Ryder, Neil S, Dean, Charles R, Smith, Thomas M

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An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries von Mulrooney, Carol A., Lahr, David L., Quintin, Michael J., Youngsaye, Willmen, Moccia, Dennis, Asiedu, Jacob K., Mulligan, Evan L., Akella, Lakshmi B., Marcaurelle, Lisa A., Montgomery, Philip, Bittker, Joshua A., Clemons, Paul A., Brudz, Stephen, Dandapani, Sivaraman, Duvall, Jeremy R., Tolliday, Nicola J., De Souza, Andrea

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Bitrophic and tritrophic effects of Bt Cry3A transgenic potato on beneficial, non-target, beetles von FERRY, Natalie, MULLIGAN, Evan A, MAJERUS, Michael E. N, GATEHOUSE, Angharad M. R

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Characterisation of adult green lacewing (Chrysoperla carnea) digestive physiology: impact of a cysteine protease inhibitor and a synthetic pyrethroid von Mulligan, Evan A, Ferry, Natalie, Jouanin, Lise, Romeis, Jörg, Gatehouse, Angharad M.R

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Comparing the impact of conventional pesticide and use of a transgenic pest-resistant crop on the beneficial carabid beetle Pterostichus melanarius von Mulligan, E.A, Ferry, N, Jouanin, L, Walters, K.F.A, Port, G.R, Gatehouse, A.M.R

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A phase II study of the potent PARP inhibitor, Rucaparib (PF-01367338, AG014699), with temozolomide in patients with metastatic melanoma demonstrating evidence of chemopotentiation von Plummer, Ruth, Lorigan, Paul, Steven, Neil, Scott, Lucy, Middleton, Mark R., Wilson, Richard H., Mulligan, Evan, Curtin, Nicola, Wang, Diane, Dewji, Raz, Abbattista, Antonello, Gallo, Jorge, Calvert, Hilary

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Prey-mediated effects of transgenic canola on a beneficial, non-target, carabid beetle von FERRY, Natalie, MULLIGAN, Evan A, STEWART, C. Neal, TABASHNIK, Bruce E, PORT, Gordon R, GATEHOUSE, Angharad M. R

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High-throughput isolation of Caenorhabditis elegans deletion mutants von Liu, L X, Spoerke, J M, Mulligan, E L, Chen, J, Reardon, B, Westlund, B, Sun, L, Abel, K, Armstrong, B, Hardiman, G, King, J, McCague, L, Basson, M, Clover, R, Johnson, C D

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Mitoxantrone in combination with an inhibitor of DNA‐dependent protein kinase: a potential therapy for high risk B‐cell chronic lymphocytic leukaemia von Elliott, Sarah L., Crawford, Clark, Mulligan, Evan, Summerfield, Geoffrey, Newton, Paula, Wallis, Jonathan, Mainou‐Fowler, Tryfonia, Evans, Paul, Bedwell, Clare, Durkacz, Barbara W., Willmore, Elaine

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Influence of Bt-transgenic pollen, Bt-toxin and protease inhibitor (SBTI) ingestion on development of the hypopharyngeal glands in honeybees von BABENDREIER, Dirk, KALBERER, Nicole M, ROMEIS, Jörg, FLURI, Peter, MULLIGAN, Evan, BIGLER, Franz

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P B S-1086, a “Pan-Rel” Inhibitor, Decreases Viability of Chronic Lymphocytic Leukemia Cells von Tudhope, Susan J, Mulligan, Evan A, Hunter, Jill E, Summerfield, Geoffrey P, Marshall, Scott, Wallis, Jonathan, Marr, Helen, Evans, Paul, Lowe, Chris, Durkacz, Barbara W, Zhang, Jie, Meshulam, Jeffrey, Bobb, Kathryn, Willmore, Elaine

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ATM Mutant Chronic Lymphocytic Leukaemia Cells are Chemosensitized by Inhibition of DNA-Dependent Protein Kinase von Willmore, Elaine, Skowronska, Ana, Mulligan, Evan A, Ahmed, G., Elliott, Sarah, Summerfield, Geoffrey P, Hamlen, Karen, Lowe, Chris, Durkacz, Barbara W, Stankovic, Tanja

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Relationships Between Aberrant Activity of the NF-κB Subunits and Outcome In Chronic Lymphocytic Leukemia: The Dual Role of DNA Damage Sensor Enzymes von Mulligan, Evan A, Hunter, Jill E, Baird, Arabella EG, Elliott, Sarah, Summerfield, Geoffrey P, Hamlen, Karen, Lowe, Chris, Wallis, Jonathan, Veuger, Stephany, Durkacz, Barbara W, Willmore, Elaine

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Effective sensitization of temozolomide by ABT-888 is lost with development of TMZ resistance in glioblastoma xenograft lines von Clarke, Michelle J., Mulligan, Evan A., Grogan, Patrick T., Mladek, Ann C., Carlson, Brett L., Schroeder, Mark A., Curtin, Nicola J., Lou, Zhenkun, Decker, Paul A., Wu, Wenting, Plummer, E. Ruth, Sarkaria, Jann N.

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