Discovery of IDO1 Inhibitors: From Bench to Bedside von Prendergast, George C, Malachowski, William P, DuHadaway, James B, Muller, Alexander J

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Inhibiting IDO pathways to treat cancer: lessons from the ECHO-301 trial and beyond von Muller, Alexander J., Manfredi, Mark G., Zakharia, Yousef, Prendergast, George C.

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Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses von Merlo, Lauren M. F., DuHadaway, James B., Montgomery, James D., Peng, Wei-Dan, Murray, Peter J., Prendergast, George C., Caton, Andrew J., Muller, Alexander J., Mandik-Nayak, Laura

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IDO1 and inflammatory neovascularization: bringing new blood to tumor-promoting inflammation von Muller, Alexander J, Mondal, Arpita, Dey, Souvik, Prendergast, George C

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Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan von METZ, Richard, DUHADAWAY, James B, KAMASANI, Uma, LAURY-KLEINTOP, Lisa, MUTTER, Alexander J, PRENDERGAST, George C

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Indoximod: An Immunometabolic Adjuvant That Empowers T Cell Activity in Cancer von Fox, Eric, Oliver, Thomas, Rowe, Melissa, Thomas, Sunil, Zakharia, Yousef, Gilman, Paul B, Muller, Alexander J, Prendergast, George C

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The Immunomodulatory Enzyme IDO2 Mediates Autoimmune Arthritis through a Nonenzymatic Mechanism von Merlo, Lauren M F, Peng, Weidan, DuHadaway, James B, Montgomery, James D, Prendergast, George C, Muller, Alexander J, Mandik-Nayak, Laura

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IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation von Metz, Richard, Smith, Courtney, DuHadaway, James B, Chandler, Phillip, Baban, Babak, Merlo, Lauren M F, Pigott, Elizabeth, Keough, Martin P, Rust, Sonja, Mellor, Andrew L, Mandik-Nayak, Laura, Muller, Alexander J, Prendergast, George C

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IDO is a nodal pathogenic driver of lung cancer and metastasis development von Smith, Courtney, Chang, Mee Young, Parker, Katherine H, Beury, Daniel W, DuHadaway, James B, Flick, Hollie E, Boulden, Janette, Sutanto-Ward, Erika, Soler, Alejandro Peralta, Laury-Kleintop, Lisa D, Mandik-Nayak, Laura, Metz, Richard, Ostrand-Rosenberg, Suzanne, Prendergast, George C, Muller, Alexander J

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Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase von Winters, Maria, DuHadaway, James B., Pham, Khoa N., Lewis-Ballester, Ariel, Badir, Shorouk, Wai, Jenny, Sheikh, Eesha, Yeh, Syun-Ru, Prendergast, George C., Muller, Alexander J., Malachowski, William P.

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Host IDO2 Gene Status Influences Tumor Progression and Radiotherapy Response in KRAS -Driven Sporadic Pancreatic Cancers von Nevler, Avinoam, Muller, Alexander J, Sutanto-Ward, Erika, DuHadaway, James B, Nagatomo, Kei, Londin, Eric, O'Hayer, Kevin, Cozzitorto, Joseph A, Lavu, Harish, Yeo, Theresa P, Curtis, Mark, Villatoro, Tatiana, Leiby, Benjamin E, Mandik-Nayak, Laura, Winter, Jordan M, Yeo, Charles J, Prendergast, George C, Brody, Jonathan R

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Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase von Muller, Alexander J, Sharma, Madhav D, Chandler, Phillip R, DuHadaway, James B, Everhart, Mary E, Johnson, Burles A. III, Kahler, David J, Pihkala, Jeanene, Soler, Alejandro Peralta, Munn, David H, Prendergast, George C, Mellor, Andrew L

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Editorial: Targeting Indoleamine 2,3-dioxygenases and Tryptophan Dioxygenase for Cancer Immunotherapy von Brochez, Lieve, Kruse, Vibeke, Schadendorf, Dirk, Muller, Alexander J., Prendergast, George C.

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Indoleamine 2,3-Dioxygenase Is the Anticancer Target for a Novel Series of Potent Naphthoquinone-Based Inhibitors von Kumar, Sanjeev, Malachowski, William P, DuHadaway, James B, LaLonde, Judith M, Carroll, Patrick J, Jaller, Daniel, Metz, Richard, Prendergast, George C, Muller, Alexander J

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The Immunoregulatory Enzyme IDO Paradoxically Drives B Cell-Mediated Autoimmunity von Scott, Grant N, DuHadaway, James, Pigott, Elizabeth, Ridge, Natalie, Prendergast, George C, Muller, Alexander J, Mandik-Nayak, Laura

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Peptide vaccination directed against IDO1-expressing immune cells elicits CD8+ and CD4+ T-cell-mediated antitumor immunity and enhanced anti-PD1 responses von Dey, Souvik, Sutanto-Ward, Erika, Kopp, Katharina L, DuHadaway, James, Mondal, Arpita, Ghaban, Dema, Lecoq, Inés, Zocca, Mai-Britt, Merlo, Lauren M F, Mandik-Nayak, Laura, Andersen, Mads Hald, Pedersen, Ayako Wakatsuki, Muller, Alexander J

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Structure−Activity Study of Brassinin Derivatives as Indoleamine 2,3-Dioxygenase Inhibitors von Gaspari, Paul, Banerjee, Tinku, Malachowski, William P, Muller, Alexander J, Prendergast, George C, DuHadaway, James, Bennett, Shauna, Donovan, Ashley M

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Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer von Prendergast, George C., Smith, Courtney, Thomas, Sunil, Mandik-Nayak, Laura, Laury-Kleintop, Lisa, Metz, Richard, Muller, Alexander J.

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The Host Microbiome Regulates and Maintains Human Health: A Primer and Perspective for Non-Microbiologists von Thomas, Sunil, Izard, Jacques, Walsh, Emily, Batich, Kristen, Chongsathidkiet, Pakawat, Clarke, Gerard, Sela, David A, Muller, Alexander J, Mullin, James M, Albert, Korin, Gilligan, John P, DiGuilio, Katherine, Dilbarova, Rima, Alexander, Walker, Prendergast, George C

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Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape von Katz, Jessica B, Muller, Alexander J, Prendergast, George C

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