Discovery of IDO1 Inhibitors: From Bench to Bedside von Prendergast, George C, Malachowski, William P, DuHadaway, James B, Muller, Alexander J

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Inhibiting IDO pathways to treat cancer: lessons from the ECHO-301 trial and beyond von Muller, Alexander J., Manfredi, Mark G., Zakharia, Yousef, Prendergast, George C.

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Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer von Prendergast, George C., Smith, Courtney, Thomas, Sunil, Mandik-Nayak, Laura, Laury-Kleintop, Lisa, Metz, Richard, Muller, Alexander J.

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The Host Microbiome Regulates and Maintains Human Health: A Primer and Perspective for Non-Microbiologists von Thomas, Sunil, Izard, Jacques, Walsh, Emily, Batich, Kristen, Chongsathidkiet, Pakawat, Clarke, Gerard, Sela, David A, Muller, Alexander J, Mullin, James M, Albert, Korin, Gilligan, John P, DiGuilio, Katherine, Dilbarova, Rima, Alexander, Walker, Prendergast, George C

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Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape von Katz, Jessica B, Muller, Alexander J, Prendergast, George C

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IDO1 and inflammatory neovascularization: bringing new blood to tumor-promoting inflammation von Muller, Alexander J, Mondal, Arpita, Dey, Souvik, Prendergast, George C

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IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation von Metz, Richard, Smith, Courtney, DuHadaway, James B, Chandler, Phillip, Baban, Babak, Merlo, Lauren M F, Pigott, Elizabeth, Keough, Martin P, Rust, Sonja, Mellor, Andrew L, Mandik-Nayak, Laura, Muller, Alexander J, Prendergast, George C

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Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses von Merlo, Lauren M F, DuHadaway, James B, Montgomery, James D, Peng, Wei-Dan, Murray, Peter J, Prendergast, George C, Caton, Andrew J, Muller, Alexander J, Mandik-Nayak, Laura

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Indoximod: An Immunometabolic Adjuvant That Empowers T Cell Activity in Cancer von Fox, Eric, Oliver, Thomas, Rowe, Melissa, Thomas, Sunil, Zakharia, Yousef, Gilman, Paul B, Muller, Alexander J, Prendergast, George C

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Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan von METZ, Richard, DUHADAWAY, James B, KAMASANI, Uma, LAURY-KLEINTOP, Lisa, MUTTER, Alexander J, PRENDERGAST, George C

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The Immunomodulatory Enzyme IDO2 Mediates Autoimmune Arthritis through a Nonenzymatic Mechanism von Merlo, Lauren M F, Peng, Weidan, DuHadaway, James B, Montgomery, James D, Prendergast, George C, Muller, Alexander J, Mandik-Nayak, Laura

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IDO is a nodal pathogenic driver of lung cancer and metastasis development von Smith, Courtney, Chang, Mee Young, Parker, Katherine H, Beury, Daniel W, DuHadaway, James B, Flick, Hollie E, Boulden, Janette, Sutanto-Ward, Erika, Soler, Alejandro Peralta, Laury-Kleintop, Lisa D, Mandik-Nayak, Laura, Metz, Richard, Ostrand-Rosenberg, Suzanne, Prendergast, George C, Muller, Alexander J

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Inflammatory Reprogramming with IDO1 Inhibitors: Turning Immunologically Unresponsive 'Cold' Tumors 'Hot' von Prendergast, George C, Mondal, Arpita, Dey, Souvik, Laury-Kleintop, Lisa D, Muller, Alexander J

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Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase von Winters, Maria, DuHadaway, James B., Pham, Khoa N., Lewis-Ballester, Ariel, Badir, Shorouk, Wai, Jenny, Sheikh, Eesha, Yeh, Syun-Ru, Prendergast, George C., Muller, Alexander J., Malachowski, William P.

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Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors von Muller, Alexander J, Scherle, Peggy A

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Host IDO2 Gene Status Influences Tumor Progression and Radiotherapy Response in KRAS -Driven Sporadic Pancreatic Cancers von Nevler, Avinoam, Muller, Alexander J, Sutanto-Ward, Erika, DuHadaway, James B, Nagatomo, Kei, Londin, Eric, O'Hayer, Kevin, Cozzitorto, Joseph A, Lavu, Harish, Yeo, Theresa P, Curtis, Mark, Villatoro, Tatiana, Leiby, Benjamin E, Mandik-Nayak, Laura, Winter, Jordan M, Yeo, Charles J, Prendergast, George C, Brody, Jonathan R

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IDO2 in Immunomodulation and Autoimmune Disease von Prendergast, George C, Metz, Richard, Muller, Alexander J, Merlo, Lauren M F, Mandik-Nayak, Laura

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Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1 , potentiates cancer chemotherapy von Prendergast, George C, Muller, Alexander J, DuHadaway, James B, Donover, P Scott, Sutanto-Ward, Erika

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IDO2 Modulates T Cell-Dependent Autoimmune Responses through a B Cell-Intrinsic Mechanism von Merlo, Lauren M F, DuHadaway, James B, Grabler, Samantha, Prendergast, George C, Muller, Alexander J, Mandik-Nayak, Laura

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Towards a genetic definition of cancer-associated inflammation: role of the IDO pathway von Prendergast, George C, Metz, Richard, Muller, Alexander J

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