Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Dis... von Schwartz, Jordan Ari, Clayton, Kiera L, Mujib, Shariq, Zhang, Hongliang, Rahman, A K M Nur-Ur, Liu, Jun, Yue, Feng Yun, Benko, Erika, Kovacs, Colin, Ostrowski, Mario A

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Tim-3 negatively regulates cytotoxicity in exhausted CD8+ T cells in HIV infection von Sakhdari, Ali, Mujib, Shariq, Vali, Bahareh, Yue, Feng Yun, MacParland, Sonya, Clayton, Kiera, Jones, Richard Bradley, Liu, Jun, Lee, Erika Yue, Benko, Erika, Kovacs, Colin, Gommerman, Jennifer, Kaul, Rupert, Ostrowski, Mario A

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Effect of IL-7 Therapy on Phospho-Ribosomal Protein S6 and TRAF1 Expression in HIV-Specific CD8 T Cells in Patients Receiving Antiretroviral Therapy von Wang, Chao, Edilova, Maria I, Wagar, Lisa E, Mujib, Shariq, Singer, Meromit, Bernard, Nicole F, Croughs, Thérèse, Lederman, Michael M, Sereti, Irini, Fischl, Margaret A, Kremmer, Elisabeth, Ostrowski, Mario, Routy, Jean-Pierre, Watts, Tania H

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LINE-1 Retrotransposable Element DNA Accumulates in HIV-1-Infected Cells von Jones, R Brad, Song, Haihan, Xu, Yang, Garrison, Keith E, Buzdin, Anton A, Anwar, Naveed, Hunter, Diana V, Mujib, Shariq, Mihajlovic, Vesna, Martin, Eric, Lee, Erika, Kuciak, Monika, Raposo, Rui André Saraiva, Bozorgzad, Ardalan, Meiklejohn, Duncan A, Ndhlovu, Lishomwa C, Nixon, Douglas F, Ostrowski, Mario A

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HIV delays IFN-α production from human plasmacytoid dendritic cells and is associated with SYK phosphorylation von Lo, Calvin C, Schwartz, Jordan A, Johnson, Dylan J, Yu, Monica, Aidarus, Nasra, Mujib, Shariq, Benko, Erika, Hyrcza, Martin, Kovacs, Colin, Ostrowski, Mario A

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Abstract 1676: A comprehensive whole blood CyTOF immune monitoring panel with expanded surface and intracellular markers using the Maxpar Direct Immune Profiling Assay von Mujib, Shariq, Li, Stephen K., Zabinyakov, Nick, Loh, Christina

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A single-tube, 44-marker CyTOF assay to assess antigen-specific immunity in whole blood human samples with data analysis solution von Mujib, Shariq, Li, Stephen, Zabinyakov, Nick, Loh, Christina

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Human Endogenous Retrovirus K(HML-2) Gag- and Env-Specific T-Cell Responses Are Infrequently Detected in HIV-1-Infected Subjects Using Standard Peptide Matrix-Based Screening von Jones, R Brad, John, Vivek M, Hunter, Diana V, Martin, Eric, Mujib, Shariq, Mihajlovic, Vesna, Burgers, Peter C, Luider, Theo M, Gyenes, Gabor, Sheppard, Neil C, Sengupta, Devi, Tandon, Ravi, Yue, Feng-Yun, Benko, Erika, Kovacs, Colin, Nixon, Douglas F, Ostrowski, Mario A

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Human Immunodeficiency Virus Type 1 Escapes from Interleukin-2-Producing CD4+ T-Cell Responses without High-Frequency Fixation of Mutations von BRAD JONES, R, YUE, Feng-Yun, OSTROWSKI, Mario A, GU, Xiao Xiao Jenny, HUNTER, Diana V, MUJIB, Shariq, GYENES, Gabor, MASON, Rosemarie D, MOHAMED, Ruqaya, MACDONALD, Kelly S, KOVACS, Colin

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Sigmoid Th17 populations, the HIV latent reservoir, and microbial translocation in men on long-term antiretroviral therapy von CHEGE, Duncan, SHETH, Prameet M, KAUL, Rupert, KAIN, Taylor, KIM, Connie J, KOVACS, Colin, LOUTFY, Mona, HALPENNY, Roberta, KANDEL, Gabor, CHUN, Tae-Wook, OSTROWSKI, Mario

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Expanding the capabilities of the Maxpar Direct Immune Profiling Assay with additional markers, and customization of the analysis model in Maxpar Pathsetter von Li, Stephen K.H., Mujib, Shariq, Cohen, Michael, Yao, Huihui, Majonis, Daniel, Loh, Christina

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T cell Ig and mucin domain-containing protein 3 is recruited to the immune synapse, disrupts stable synapse formation, and associates with receptor phosphatases von Clayton, Kiera L, Haaland, Matthew S, Douglas-Vail, Matthew B, Mujib, Shariq, Chew, Glen M, Ndhlovu, Lishomwa C, Ostrowski, Mario A

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HIV Subtype and Nef-Mediated Immune Evasion Function Correlate with Viral Reservoir Size in Early-Treated Individuals von Omondi, Fredrick H, Chandrarathna, Sandali, Mujib, Shariq, Brumme, Chanson J, Jin, Steven W, Sudderuddin, Hanwei, Miller, Rachel L, Rahimi, Asa, Laeyendecker, Oliver, Bonner, Phil, Yue, Feng Yun, Benko, Erika, Kovacs, Colin M, Brockman, Mark A, Ostrowski, Mario, Brumme, Zabrina L

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Comprehensive Cross-Clade Characterization of Antibody-Mediated Recognition, Complement-Mediated Lysis, and Cell-Mediated Cytotoxicity of HIV-1 Envelope-Specific Antibodies toward... von Mujib, Shariq, Liu, Jun, Rahman, A K M Nur-Ur, Schwartz, Jordan A, Bonner, Phil, Yue, Feng Yun, Ostrowski, Mario A

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Early Initiation of Combination Antiretroviral Therapy in HIV-1–Infected Newborns Can Achieve Sustained Virologic Suppression With Low Frequency of CD4+T Cells Carrying HIV in Peri... von Bitnun, Ari, Samson, Lindy, Chun, Tae-Wook, Kakkar, Fatima, Brophy, Jason, Murray, Danielle, Justement, Shawn, Soudeyns, Hugo, Ostrowski, Mario, Mujib, Shariq, Harrigan, P. Richard, Kim, John, Sandstrom, Paul, Read, Stanley E.

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Antigen-independent induction of Tim-3 expression on human T cells by the common γ-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on... von Mujib, Shariq, Jones, R Brad, Lo, Calvin, Aidarus, Nasra, Clayton, Kiera, Sakhdari, Ali, Benko, Erika, Kovacs, Colin, Ostrowski, Mario A

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Self-assembling peptide for co-delivery of HIV-1 CD8+ T cells epitope and Toll-like receptor 7/8 agonists R848 to induce maturation of monocyte derived dendritic cell and augment p... von Ding, Yong, Liu, Jun, Lu, Sheng, Igweze, Justice, Xu, Wen, Kuang, Da, Zealey, Chris, Liu, Daheng, Gregor, Alex, Bozorgzad, Ardalan, Zhang, Lei, Yue, Elizabeth, Mujib, Shariq, Ostrowski, Mario, Chen, P.

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HIV-Specific Granzyme B-Secreting but Not Gamma Interferon-Secreting T Cells Are Associated with Reduced Viral Reservoirs in Early HIV Infection von Yue, Feng Yun, Cohen, Jared C, Ho, Mu, Rahman, A K M Nur-Ur, Liu, Jun, Mujib, Shariq, Saiyed, Aamir, Hundal, Sabrina, Khozin, Alexandra, Bonner, Phil, Liu, Daheng, Benko, Erika, Kovacs, Colin, Ostrowski, Mario

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Elevated glycolysis imparts functional ability to CD8 + T cells in HIV infection von Rahman, Akm Nur-Ur, Liu, Jun, Mujib, Shariq, Kidane, Segen, Ali, Arman, Szep, Steven, Han, Carrie, Bonner, Phil, Parsons, Michael, Benko, Erika, Kovacs, Colin, Yue, Feng Yun, Ostrowski, Mario

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HERV-K-specific T cells eliminate diverse HIV-1/2 and SIV primary isolates von Jones, R Brad, Garrison, Keith E, Mujib, Shariq, Mihajlovic, Vesna, Aidarus, Nasra, Hunter, Diana V, Martin, Eric, John, Vivek M, Zhan, Wei, Faruk, Nabil F, Gyenes, Gabor, Sheppard, Neil C, Priumboom-Brees, Ingrid M, Goodwin, David A, Chen, Lianchun, Rieger, Melanie, Muscat-King, Sophie, Loudon, Peter T, Stanley, Cole, Holditch, Sara J, Wong, Jessica C, Clayton, Kiera, Duan, Erick, Song, Haihan, Xu, Yang, SenGupta, Devi, Tandon, Ravi, Sacha, Jonah B, Brockman, Mark A, Benko, Erika, Kovacs, Colin, Nixon, Douglas F, Ostrowski, Mario A

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