2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer von Blomme, Arnaud, Ford, Catriona A., Mui, Ernest, Patel, Rachana, Ntala, Chara, Jamieson, Lauren E., Planque, Mélanie, McGregor, Grace H., Peixoto, Paul, Hervouet, Eric, Nixon, Colin, Salji, Mark, Gaughan, Luke, Markert, Elke, Repiscak, Peter, Sumpton, David, Blanco, Giovanny Rodriguez, Lilla, Sergio, Kamphorst, Jurre J., Graham, Duncan, Faulds, Karen, MacKay, Gillian M., Fendt, Sarah-Maria, Zanivan, Sara, Leung, Hing Y.

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PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer von Galbraith, Laura C. A., Mui, Ernest, Nixon, Colin, Hedley, Ann, Strachan, David, MacKay, Gillian, Sumpton, David, Sansom, Owen J., Leung, Hing Y., Ahmad, Imran

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NALP1 Influences Susceptibility to Human Congenital Toxoplasmosis, Proinflammatory Cytokine Response, and Fate of Toxoplasma gondii-Infected Monocytic Cells von Witola, William H, Mui, Ernest, Hargrave, Aubrey, Liu, Susan, Hypolite, Magali, Montpetit, Alexandre, Cavailles, Pierre, Bisanz, Cordelia, Cesbron-Delauw, Marie-France, Fournié, Gilbert J, McLeod, Rima

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Increased T-cell Infiltration Elicited by Erk5 Deletion in a Pten -Deficient Mouse Model of Prostate Carcinogenesis von Loveridge, Carolyn J, Mui, Ernest J, Patel, Rachana, Tan, Ee Hong, Ahmad, Imran, Welsh, Michelle, Galbraith, Julie, Hedley, Ann, Nixon, Colin, Blyth, Karen, Sansom, Owen, Leung, Hing Y

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P2X7 receptor-mediated killing of an intracellular parasite, Toxoplasma gondii, by human and murine macrophages von Lees, Michael P, Fuller, Stephen J, McLeod, Rima, Boulter, Nicola R, Miller, Catherine M, Zakrzewski, Alana M, Mui, Ernest J, Witola, William H, Coyne, Jessica J, Hargrave, Aubrey C, Jamieson, Sarra E, Blackwell, Jenefer M, Wiley, James S, Smith, Nicholas C

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Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasi... von Hermes, Gretchen, Ajioka, James W, Kelly, Krystyna A, Mui, Ernest, Roberts, Fiona, Kasza, Kristen, Mayr, Thomas, Kirisits, Michael J, Wollmann, Robert, Ferguson, David J P, Roberts, Craig W, Hwang, Jong-Hee, Trendler, Toria, Kennan, Richard P, Suzuki, Yasuhiro, Reardon, Catherine, Hickey, William F, Chen, Lieping, McLeod, Rima

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Spiroindolone That Inhibits PfATPase4 Is a Potent, Cidal Inhibitor of Toxoplasma gondii Tachyzoites In Vitro and In Vivo von YING ZHOU, FOMOVSKA, Alina, MUENCH, Stephen, LAI, Bo-Shiun, MUI, Ernest, MCLEOD, Rima

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Genetic and epigenetic factors at COL2A1 and ABCA4 influence clinical outcome in congenital toxoplasmosis von Jamieson, Sarra E, de Roubaix, Lee-Anne, Cortina-Borja, Mario, Tan, Hooi Kuan, Mui, Ernest J, Cordell, Heather J, Kirisits, Michael J, Miller, E Nancy, Peacock, Christopher S, Hargrave, Aubrey C, Coyne, Jessica J, Boyer, Kenneth, Bessieres, Marie-Hélène, Buffolano, Wilma, Ferret, Nicole, Franck, Jacqueline, Kieffer, François, Meier, Paul, Nowakowska, Dorota E, Paul, Malgorzata, Peyron, François, Stray-Pedersen, Babill, Prusa, Andrea-Romana, Thulliez, Philippe, Wallon, Martine, Petersen, Eskild, McLeod, Rima, Gilbert, Ruth E, Blackwell, Jenefer M

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THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer von Blomme, Arnaud, Peter, Coralie, Mui, Ernest, Rodriguez Blanco, Giovanny, An, Ning, Mason, Louise M, Jamieson, Lauren E, McGregor, Grace H, Lilla, Sergio, Ntala, Chara, Patel, Rachana, Thiry, Marc, Kung, Sonia H Y, Leclercq, Marine, Ford, Catriona A, Rushworth, Linda K, McGarry, David J, Mason, Susan, Repiscak, Peter, Nixon, Colin, Salji, Mark J, Markert, Elke, MacKay, Gillian M, Kamphorst, Jurre J, Graham, Duncan, Faulds, Karen, Fazli, Ladan, Gleave, Martin E, Avezov, Edward, Edwards, Joanne, Yin, Huabing, Sumpton, David, Blyth, Karen, Close, Pierre, Murphy, Daniel J, Zanivan, Sara, Leung, Hing Y

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Towards an immunosense vaccine to prevent toxoplasmosis: Protective Toxoplasma gondii epitopes restricted by HLA-A0201 von Cong, Hua, Mui, Ernest J, Witola, William H, Sidney, John, Alexander, Jeff, Sette, Alessandro, Maewal, Ajesh, McLeod, Rima

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Identification of a Sporozoite-Specific Antigen from Toxoplasma gondii von Hill, Dolores, Coss, Cathleen, Dubey, J. P, Wroblewski, Kristen, Sautter, Mari, Hosten, Tiffany, Muñoz-Zanzi, Claudia, Mui, Ernest, Withers, Shawn, Boyer, Kenneth, Hermes, Gretchen, Coyne, Jessica, Jagdis, Frank, Burnett, Andrew, McLeod, Patrick, Morton, Holmes, Robinson, Donna, McLeod, Rima

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Molecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infections von Lai, Bo-Shiun, Witola, William H, El Bissati, Kamal, Zhou, Ying, Mui, Ernest, Fomovska, Alina, McLeod, Rima

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Identification and Development of Novel Inhibitors of Toxoplasma gondii Enoyl Reductase von Tipparaju, Suresh K, Muench, Stephen P, Mui, Ernest J, Ruzheinikov, Sergey N, Lu, Jeffrey Z, Hutson, Samuel L, Kirisits, Michael J, Prigge, Sean T, Roberts, Craig W, Henriquez, Fiona L, Kozikowski, Alan P, Rice, David W, McLeod, Rima L

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Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1 von Patel, Rachana, Fleming, Janis, Mui, Ernest, Loveridge, Carolyn, Repiscak, Peter, Blomme, Arnaud, Harle, Victoria, Salji, Mark, Ahmad, Imran, Teo, Katy, Hamdy, Freddie C, Hedley, Ann, van den Broek, Niels, Mackay, Gillian, Edwards, Joanne, Sansom, Owen J, Leung, Hing Y

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Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity von Loveridge, Carolyn J., van ’t Hof, Rob J., Charlesworth, Gemma, King, Ayala, Tan, Ee Hong, Rose, Lorraine, Daroszewska, Anna, Prior, Amanda, Ahmad, Imran, Welsh, Michelle, Mui, Ernest J., Ford, Catriona, Salji, Mark, Sansom, Owen, Blyth, Karen, Leung, Hing Y.

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Novel N-Benzoyl-2-Hydroxybenzamide Disrupts Unique Parasite Secretory Pathway von Fomovska, Alina, Huang, Qingqing, El Bissati, Kamal, Mui, Ernest J, Witola, William H, Cheng, Gang, Zhou, Ying, Sommerville, Caroline, Roberts, Craig W, Bettis, Sam, Prigge, Sean T, Afanador, Gustavo A, Hickman, Mark R, Lee, Patty J, Leed, Susan E, Auschwitz, Jennifer M, Pieroni, Marco, Stec, Jozef, Muench, Stephen P, Rice, David W, Kozikowski, Alan P, McLeod, Rima

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Novel Triazine JPC-2067-B Inhibits Toxoplasma gondii In Vitro and In Vivo von Mui, Ernest J, Schiehser, Guy A, Milhous, Wilbur K, Hsu, Honghue, Roberts, Craig W, Kirisits, Michael, Muench, Stephen, Rice, David, Dubey, J.P, Fowble, Joseph W, Rathod, Pradipsinh K, Queener, Sherry F, Liu, Susan R, Jacobus, David P, McLeod, Rima

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Toxoplasma gondii HLA-B0702-restricted GRA7(20-28) peptide with adjuvants and a universal helper T cell epitope elicits CD8(+) T cells producing interferon-γ and reduces parasite b... von Cong, Hua, Mui, Ernest J, Witola, William H, Sidney, John, Alexander, Jeff, Sette, Alessandro, Maewal, Ajesh, El Bissati, Kamal, Zhou, Ying, Suzuki, Yasuhiro, Lee, Daniel, Woods, Stuart, Sommerville, Caroline, Henriquez, Fiona L, Roberts, Craig W, McLeod, Rima

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Impaired Innate Immunity in Mice Deficient in Interleukin-1 Receptor-Associated Kinase 4 Leads to Defective Type 1 T Cell Responses, B Cell Expansion, and Enhanced Susceptibility t... von BELA, Samantha R, DUTRA, Miriam S, MUI, Ernest, MONTPETIT, Alexandre, OLIVEIRA, Fernanda S, OLIVEIRA, Sergio C, ARANTES, Rosa M. E, ANTONELLI, Lis R, MCLEOD, Rima, GAZZINELLI, Ricardo T

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The Shikimate Pathway and Its Branches in Apicomplexan Parasites von Roberts, Craig W., Roberts, Fiona, Lyons, Russell E., Kirisits, Michael J., Mui, Ernest J, Finnerty, John, Johnson, Jennifer J., Ferguson, David J. P., Coggins, John R., Krell, Tino, Coombs, Graham H., Milhous, Wilbur K., Kyle, Dennis E., Tzipori, Saul, Barnwell, John, Dame, John B., Jane, Carlton, McLeod, Rima

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