Discovery of an MLLT1/3 YEATS Domain Chemical Probe von Moustakim, Moses, Christott, Thomas, Monteiro, Octovia P., Bennett, James, Giroud, Charline, Ward, Jennifer, Rogers, Catherine M., Smith, Paul, Panagakou, Ioanna, Díaz‐Sáez, Laura, Felce, Suet Ling, Gamble, Vicki, Gileadi, Carina, Halidi, Nadia, Heidenreich, David, Chaikuad, Apirat, Knapp, Stefan, Huber, Kilian V. M., Farnie, Gillian, Heer, Jag, Manevski, Nenad, Poda, Gennady, Al‐awar, Rima, Dixon, Darren J., Brennan, Paul E., Fedorov, Oleg

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Discovery of a PCAF Bromodomain Chemical Probe von Moustakim, Moses, Clark, Peter G. K., Trulli, Laura, Fuentes de Arriba, Angel L., Ehebauer, Matthias T., Chaikuad, Apirat, Murphy, Emma J., Mendez‐Johnson, Jacqui, Daniels, Danette, Hou, Chun‐Feng D., Lin, Yu‐Hui, Walker, John R., Hui, Raymond, Yang, Hongbing, Dorrell, Lucy, Rogers, Catherine M., Monteiro, Octovia P., Fedorov, Oleg, Huber, Kilian V. M., Knapp, Stefan, Heer, Jag, Dixon, Darren J., Brennan, Paul E.

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Structure-Based Approach toward Identification of Inhibitory Fragments for Eleven-Nineteen-Leukemia Protein (ENL) von Heidenreich, David, Moustakim, Moses, Schmidt, Jurema, Merk, Daniel, Brennan, Paul E, Fedorov, Oleg, Chaikuad, Apirat, Knapp, Stefan

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Discovery of a PCAF Bromodomain Chemical Probe von Moustakim, Moses, Clark, Peter G. K., Trulli, Laura, Fuentes de Arriba, Angel L., Ehebauer, Matthias T., Chaikuad, Apirat, Murphy, Emma J., Mendez‐Johnson, Jacqui, Daniels, Danette, Hou, Chun‐Feng D., Lin, Yu‐Hui, Walker, John R., Hui, Raymond, Yang, Hongbing, Dorrell, Lucy, Rogers, Catherine M., Monteiro, Octovia P., Fedorov, Oleg, Huber, Kilian V. M., Knapp, Stefan, Heer, Jag, Dixon, Darren J., Brennan, Paul E.

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Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2 von Moustakim, Moses, Riedel, Kerstin, Schuller, Marion, Gehring, Andrè P., Monteiro, Octovia P., Martin, Sarah P., Fedorov, Oleg, Heer, Jag, Dixon, Darren J., Elkins, Jonathan M., Knapp, Stefan, Bracher, Franz, Brennan, Paul E.

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Chemical probes and inhibitors of bromodomains outside the BET family von Moustakim, Moses, Clark, Peter G K, Hay, Duncan A, Dixon, Darren J, Brennan, Paul E

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Chemical probes and inhibitors of bromodomains outside the BET familyThe authors declare no competing interests von Moustakim, Moses, Clark, Peter G. K, Hay, Duncan A, Dixon, Darren J, Brennan, Paul E

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Chemical probes and inhibitors of bromodomains outside the BET family† †The authors declare no competing interests von Moustakim, Moses, Clark, Peter G. K., Hay, Duncan A., Dixon, Darren J., Brennan, Paul E.

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Abstract 3425: The discovery and characterization of CFT1946: A potent, selective, and orally bioavailable degrader of mutant BRAF for the treatment of BRAF-driven cancers von Liang, Yanke, Sowa, Mathew E., Jackson, Katrina L., Simard, Jeffrey R., Kreger, Bridget, Li, Ping, Poling, Laura, Baddour, Joelle, Good, Andrew, Huang, Hongwei, Eron, Scott, Nasveschuk, Christopher G., Yu, Robert, Fitzgerald, Mark, Garza, Victoria, O’Shea, Morgan W., Veits, Gesine, Yap, Jeremy Y., Moustakim, Moses, Hart, Ashley, Agafonov, Roman V., Sarkissian, Grace, Patel, Joe S., Deibler, Richard, Cole, Kyle S., Cocozziello, David, Rahman, Fazlur, Phillips, Andrew J., Norton, Elizabeth, Crystal, Adam S., Pollock, Roy M., Fisher, Stewart L.

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Back Cover: Discovery of a PCAF Bromodomain Chemical Probe (Angew. Chem. Int. Ed. 3/2017) von Moustakim, Moses, Clark, Peter G. K., Trulli, Laura, Fuentes de Arriba, Angel L., Ehebauer, Matthias T., Chaikuad, Apirat, Murphy, Emma J., Mendez‐Johnson, Jacqui, Daniels, Danette, Hou, Chun‐Feng D., Lin, Yu‐Hui, Walker, John R., Hui, Raymond, Yang, Hongbing, Dorrell, Lucy, Rogers, Catherine M., Monteiro, Octovia P., Fedorov, Oleg, Huber, Kilian V. M., Knapp, Stefan, Heer, Jag, Dixon, Darren J., Brennan, Paul E.

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Abstract ND09: The discovery and characterization of CFT8634: A potent and selective degrader of BRD9 for the treatment of SMARCB1-perturbed cancers von Jackson, Katrina L., Agafonov, Roman V., Carlson, Mark W., Chaturvedi, Prasoon, Cocozziello, David, Cole, Kyle, Deibler, Richard, Eron, Scott J., Good, Andrew, Hart, Ashley A., He, Minsheng, Henderson, Christina S., Huang, Hongwei, Isasa, Marta, Kirby, R. Jason, Lee, Linda, Mahler, Michelle, Moustakim, Moses, Nasveschuk, Christopher G., Palmer, Michael, Poling, Laura L., Pollock, Roy M., Schnaderbeck, Matthew, Spence, Stan, Veits, Gesine K., Yap, Jeremy L., Yin, Ning, Zeid, Rhamy, Crystal, Adam S., Phillips, Andrew J., Fisher, Stewart L.

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Target Identification Using Chemical Probes von Moustakim, Moses, Felce, Suet Ling, Zaarour, Nancy, Farnie, Gillian, McCann, Fiona E, Brennan, Paul E

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Rücktitelbild: Discovery of a PCAF Bromodomain Chemical Probe (Angew. Chem. 3/2017) von Moustakim, Moses, Clark, Peter G. K., Trulli, Laura, Fuentes de Arriba, Angel L., Ehebauer, Matthias T., Chaikuad, Apirat, Murphy, Emma J., Mendez‐Johnson, Jacqui, Daniels, Danette, Hou, Chun‐Feng D., Lin, Yu‐Hui, Walker, John R., Hui, Raymond, Yang, Hongbing, Dorrell, Lucy, Rogers, Catherine M., Monteiro, Octovia P., Fedorov, Oleg, Huber, Kilian V. M., Knapp, Stefan, Heer, Jag, Dixon, Darren J., Brennan, Paul E.

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TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 von GOOD, Andrew, NASVESCHUK, Christopher, MOUSTAKIM, Moses, HENDERSON, James, PROIA, David

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PROTEIN STABILIZING COMPOUNDS CONTAINING USP7 LIGANDS von STEEL, Richard James, SPROTT, Kevin Tyler, MOUSTAKIM, Moses, KASS, Jorden, SAULNIER, Mark George, BOWMAN, Brian

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TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY von ANDERSON, Corey, NASVESCHUK, Christopher, GARZA, Victoria, LIANG, Yanke, O'SHEA, Morgan, MOUSTAKIM, Moses, HENDERSON, James

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TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 von GOOD, Andrew, NASVESCHUK, Christopher, MOUSTAKIM, Moses, HENDERSON, James, PROIA, David

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TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 von Henderson, James A, Prola, David, Nasveschuk, Christopher G, Good, Andrew Charies, Moustakim, Moses

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TRICYCLIC LIGANDS FOR DEGRADATION OF IKZF2 OR IKZF4 von HENDERSON, James, A, GOOD, Andrew, Charles, NASVESCHUK, Christopher, G, MOUSTAKIM, Moses, PROIA, David

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TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY von ANDERSON, Corey, NASVESCHUK, Christopher, GARZA, Victoria, LIANG, Yanke, O'SHEA, Morgan, MOUSTAKIM, Moses, HENDERSON, James

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