High contiguity Arabidopsis thaliana genome assembly with a single nanopore flow cell von Michael, Todd P., Jupe, Florian, Bemm, Felix, Motley, S. Timothy, Sandoval, Justin P., Lanz, Christa, Loudet, Olivier, Weigel, Detlef, Ecker, Joseph R.

Volltext

A new Cannabis genome assembly associates elevated cannabidiol (CBD) with hemp introgressed into marijuana von Grassa, Christopher J., Weiblen, George D., Wenger, Jonathan P., Dabney, Clemon, Poplawski, Shane G., Timothy Motley, S., Michael, Todd P., Schwartz, C. J.

Volltext

The complex architecture and epigenomic impact of plant T-DNA insertions von Jupe, Florian, Rivkin, Angeline C, Michael, Todd P, Zander, Mark, Motley, S Timothy, Sandoval, Justin P, Slotkin, R Keith, Chen, Huaming, Castanon, Rosa, Nery, Joseph R, Ecker, Joseph R

Volltext

Generating a high‐confidence reference genome map of the Greater Duckweed by integration of cytogenomic, optical mapping, and Oxford Nanopore technologies von Hoang, Phuong N.T., Michael, Todd P., Gilbert, Sarah, Chu, Philomena, Motley, S. Timothy, Appenroth, Klaus J., Schubert, Ingo, Lam, Eric

Volltext

Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function von Kennedy, Andrew J., Rahn, Elizabeth J., Paulukaitis, Brynna S., Savell, Katherine E., Kordasiewicz, Holly B., Wang, Jing, Lewis, John W., Posey, Jessica, Strange, Sarah K., Guzman-Karlsson, Mikael C., Phillips, Scott E., Decker, Kyle, Motley, S. Timothy, Swayze, Eric E., Ecker, David J., Michael, Todd P., Day, Jeremy J., Sweatt, J. David

Volltext

Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement von Shoblock, James R., Welty, Natalie, Aluisio, Leah, Fraser, Ian, Motley, S. Timothy, Morton, Kirsten, Palmer, James, Bonaventure, Pascal, Carruthers, Nicholas I., Lovenberg, Timothy W., Boggs, Jamin, Galici, Ruggero

Volltext

JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats von Galici, Ruggero, Rezvani, Amir H., Aluisio, Leah, Lord, Brian, Levin, Edward D., Fraser, Ian, Boggs, Jamin, Welty, Natalie, Shoblock, James R., Motley, S. Timothy, Letavic, Michael A., Carruthers, Nicholas I., Dugovic, Christine, Lovenberg, Timothy W., Bonaventure, Pascal

Volltext

Multiplexed and Extraction-Free Amplification for Simplified SARS-CoV‑2 RT-PCR Tests von Byrnes, Samantha A, Gallagher, Ryan, Steadman, Amy, Bennett, Crissa, Rivera, Rafael, Ortega, Corrie, Motley, S. Timothy, Jain, Paras, Weigl, Bernhard H, Connelly, John T

Volltext

In vitro pharmacological characterization of RXFP3 allosterism: an example of probe dependency von Alvarez-Jaimes, Lily, Sutton, Steven W, Nepomuceno, Diane, Motley, S Timothy, Cik, Miroslav, Stocking, Emily, Shoblock, James, Bonaventure, Pascal

Volltext

Measurement Biases Distort Cell-Free DNA Fragmentation Profiles and Define the Sensitivity of Metagenomic Cell-Free DNA Sequencing Assays von Chang, Adrienne, Mzava, Omary, Lenz, Joan S, Cheng, Alexandre P, Burnham, Philip, Motley, S Timothy, Bennett, Crissa, Connelly, John T, Dadhania, Darshana M, Suthanthiran, Manikkam, Lee, John R, Steadman, Amy, De Vlaminck, Iwijn

Volltext

Improved multiple displacement amplification (iMDA) and ultraclean reagents von Motley, S Timothy, Picuri, John M, Crowder, Chris D, Minich, Jeremiah J, Hofstadler, Steven A, Eshoo, Mark W

Volltext

Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: Identification of candidates for clinical development von Letavic, Michael A., Aluisio, Leah, Atack, John R., Bonaventure, Pascal, Carruthers, Nicholas I., Dugovic, Christine, Everson, Anita, Feinstein, Mark A., Fraser, Ian C., Hoey, Kenway, Jiang, Xiaohui, Keith, John M., Koudriakova, Tatiana, Leung, Perry, Lord, Brian, Lovenberg, Timothy W., Ly, Kiev S., Morton, Kirsten L., Timothy Motley, S., Nepomuceno, Diane, Rizzolio, Michele, Rynberg, Raymond, Sepassi, Kia, Shelton, Jonathan

Volltext

In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain pen... von Shoblock, James R., Welty, Natalie, Nepomuceno, Diane, Lord, Brian, Aluisio, Leah, Fraser, Ian, Motley, S. Timothy, Sutton, Steve W., Morton, Kirsten, Galici, Ruggero, Atack, John R., Dvorak, Lisa, Swanson, Devin M., Carruthers, Nicholas I., Dvorak, Curt, Lovenberg, Timothy W., Bonaventure, Pascal

Volltext

The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety von Cippitelli, Andrea, Rezvani, Amir H, Robinson, J. Elliott, Eisenberg, Lindsay, Levin, Edward D, Bonaventure, Pascal, Motley, S. Timothy, Lovenberg, Timothy W, Heilig, Markus, Thorsell, Annika

Volltext

Novel pyrazole derivatives as potent inhibitors of type II topoisomerases. Part 1: Synthesis and preliminary SAR analysis von Gomez, Laurent, Hack, Michael D., Wu, Jiejun, Wiener, John J.M., Venkatesan, Hari, Santillán, Alejandro, Pippel, Daniel J., Mani, Neelakandha, Morrow, Brian J., Motley, S. Timothy, Shaw, Karen Joy, Wolin, Ronald, Grice, Cheryl A., Jones, Todd K.

Volltext

Tetrahydroindazole inhibitors of bacterial type II topoisomerases. Part 2: SAR development and potency against multidrug-resistant strains von Wiener, John J.M., Gomez, Laurent, Venkatesan, Hariharan, Santillán, Alejandro, Allison, Brett D., Schwarz, Kimberly L., Shinde, Shirin, Tang, Liu, Hack, Michael D., Morrow, Brian J., Motley, S. Timothy, Goldschmidt, Raul M., Shaw, Karen Joy, Jones, Todd K., Grice, Cheryl A.

Volltext

Simultaneous analysis of host and pathogen interactions during an in vivo infection reveals local induction of host acute phase response proteins, a novel bacterial stress response... von Motley, S. Timothy, Morrow, Brian J., Liu, Xuejun, Dodge, Ingrid L., Vitiello, Antonella, Ward, Christine K., Shaw, Karen Joy

Volltext

Multiplexed and Extraction-Free Amplification for Simplified SARSCoV-2 RT-PCR Tests von Byrnes, Samantha A., Gallagher, Ryan, Steadman, Amy, Bennett, Crissa, Rivera, Rafael, Ortega, Corrie, Motley, S. Timothy, Jain, Paras, Weigl, Bernhard H., Connelly, John T.

Volltext

2-Aryloxymethylmorpholine histamine H(3) antagonists von Letavic, Michael A, Keith, John M, Ly, Kiev S, Bonaventure, Pascal, Feinstein, Mark A, Lord, Brian, Miller, Kirsten L, Motley, S Timothy, Nepomuceno, Diane, Sutton, Steven W, Carruthers, Nicholas I

Volltext

Functional Characterization of a Serine/Threonine Protein Kinase of Pseudomonas aeruginosa von MOTLEY, S. T, LORY, S

Volltext