Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement von Shoblock, James R., Welty, Natalie, Aluisio, Leah, Fraser, Ian, Motley, S. Timothy, Morton, Kirsten, Palmer, James, Bonaventure, Pascal, Carruthers, Nicholas I., Lovenberg, Timothy W., Boggs, Jamin, Galici, Ruggero

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Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X7 Antagonists von Letavic, Michael A, Lord, Brian, Bischoff, Francois, Hawryluk, Natalie A, Pieters, Serge, Rech, Jason C, Sales, Zachary, Velter, Adriana I, Ao, Hong, Bonaventure, Pascal, Contreras, Victor, Jiang, Xiaohui, Morton, Kirsten L, Scott, Brian, Wang, Qi, Wickenden, Alan D, Carruthers, Nicholas I, Bhattacharya, Anindya

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Novel Benzamide-Based Histamine H3 Receptor Antagonists: The Identification of Two Candidates for Clinical Development von Letavic, Michael A, Aluisio, Leah, Apodaca, Richard, Bajpai, Manoj, Barbier, Ann J, Bonneville, Anne, Bonaventure, Pascal, Carruthers, Nicholas I, Dugovic, Christine, Fraser, Ian C, Kramer, Michelle L, Lord, Brian, Lovenberg, Timothy W, Li, Lilian Y, Ly, Kiev S, Mcallister, Heather, Mani, Neelakandha S, Morton, Kirsten L, Ndifor, Anthony, Nepomuceno, S. Diane, Pandit, Chennagiri R, Sands, Steven B, Shah, Chandra R, Shelton, Jonathan E, Snook, Sandra S, Swanson, Devin M, Xiao, Wei

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Indole- and benzothiophene-based histamine H3 antagonists von SANTILLAN, Alejandro, MCCLURE, Kelly J, LOVENBERG, Timothy W, CARRUTHERS, Nicholas I, GRICE, Cheryl A, ALLISON, Brett D, LORD, Brian, BOGGS, Jamin D, MORTON, Kirsten L, EVERSON, Anita M, NEPOMUCENO, Diane, LETAVIC, Michael A, LEE-DUTRA, Alice

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Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists von STOCKING, Emily M, ALUISIO, Leah, LORD, Brian, LY, Kiev S, MORTON, Kirsten L, NEPOMUCENO, Diane, SHAH, Chandravadan R, SHELTON, Jonathan, SOYODE-JOHNSON, Akinola, LETAVIC, Michael A, ATACK, John R, BONAVENTURE, Pascal, CARRUTHERS, Nicholas I, DUGOVIC, Christine, EVERSON, Anita, FRASER, Ian, XIAOHUI JIANG, LEUNG, Perry

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Safety and pharmacokinetics of recombinant factor XIII in healthy volunteers: a randomized placebo-controlled double-blind, multi-dose study von VISICH, Jennifer E, ZUCKERMAN, Linda A, BUTINE, Michael D, GUNEWARDENA, Kulasiri A, WILD, Richard, MORTON, Kirsten M, REYNOLDS, Thomas C

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Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: Identification of candidates for clinical development von Letavic, Michael A., Aluisio, Leah, Atack, John R., Bonaventure, Pascal, Carruthers, Nicholas I., Dugovic, Christine, Everson, Anita, Feinstein, Mark A., Fraser, Ian C., Hoey, Kenway, Jiang, Xiaohui, Keith, John M., Koudriakova, Tatiana, Leung, Perry, Lord, Brian, Lovenberg, Timothy W., Ly, Kiev S., Morton, Kirsten L., Timothy Motley, S., Nepomuceno, Diane, Rizzolio, Michele, Rynberg, Raymond, Sepassi, Kia, Shelton, Jonathan

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In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain pen... von Shoblock, James R., Welty, Natalie, Nepomuceno, Diane, Lord, Brian, Aluisio, Leah, Fraser, Ian, Motley, S. Timothy, Sutton, Steve W., Morton, Kirsten, Galici, Ruggero, Atack, John R., Dvorak, Lisa, Swanson, Devin M., Carruthers, Nicholas I., Dvorak, Curt, Lovenberg, Timothy W., Bonaventure, Pascal

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Indole- and benzothiophene-based histamine H 3 antagonists von Santillan, Alejandro, McClure, Kelly J., Allison, Brett D., Lord, Brian, Boggs, Jamin D., Morton, Kirsten L., Everson, Anita M., Nepomuceno, Diane, Letavic, Michael A., Lee-Dutra, Alice, Lovenberg, Timothy W., Carruthers, Nicholas I., Grice, Cheryl A.

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Heterocyclic replacement of the central phenyl core of diamine-based histamine H 3 receptor antagonists von Swanson, Devin M., Shah, Chandra R., Lord, Brian, Morton, Kirsten, Dvorak, Lisa K., Mazur, Curt, Apodaca, Richard, Xiao, Wei, Boggs, Jamin D., Feinstein, Mark, Wilson, Sandy J., Barbier, Ann J., Bonaventure, Pascal, Lovenberg, Timothy W., Carruthers, Nicholas I.

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The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y2 receptor von Swanson, Devin M., Wong, Victoria D., Jablonowski, Jill A., Shah, Chandra, Rudolph, Dale A., Dvorak, Curt A., Seierstad, Mark, Dvorak, Lisa K., Morton, Kirsten, Nepomuceno, Diane, Atack, John R., Bonaventure, Pascal, Lovenberg, Timothy W., Carruthers, Nicholas I.

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Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists von SWANSON, Devin M, SHAH, Chandra R, WILSON, Sandy J, BARBIER, Ann J, BONAVENTURE, Pascal, LOVENBERG, Timothy W, CARRUTHERS, Nicholas I, LORD, Brian, MORTON, Kirsten, DVORAK, Lisa K, MAZUR, Curt, APODACA, Richard, WEI XIAO, BOGGS, Jamin D, FEINSTEIN, Mark

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The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y sub(2) receptor von Swanson, Devin M, Wong, Victoria D, Jablonowski, Jill A, Shah, Chandra, Rudolph, Dale A, Dvorak, Curt A, Seierstad, Mark, Dvorak, Lisa K, Morton, Kirsten, Nepomuceno, Diane, Atack, John R, Bonaventure, Pascal, Lovenberg, Timothy W, Carruthers, Nicholas I

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Indole- and benzothiophene-based histamine H sub(3 antagonists) von Santillan, Alejandro, McClure, Kelly J, Allison, Brett D, Lord, Brian, Boggs, Jamin D, Morton, Kirsten L, Everson, Anita M, Nepomuceno, Diane, Letavic, Michael A, Lee-Dutra, Alice, Lovenberg, Timothy W, Carruthers, Nicholas I, Grice, Cheryl A

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In vitro and in vivo characterization of JNJ-31020028 (N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperaz in-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide), a selective brain pe... von Shoblock, James R, Welty, Natalie, Nepomuceno, Diane, Lord, Brian, Aluisio, Leah, Fraser, Ian, Motley, STimothy, Sutton, Steve W, Morton, Kirsten, Galici, Ruggero, Atack, John R, Dvorak, Lisa, Swanson, Devin M, Carruthers, Nicholas I, Dvorak, Curt, Lovenberg, Timothy W, Bonaventure, Pascal

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In vitro and in vivo characterization of JNJ-31020028 N-(4-{4-[2-(diethylamino)-2-oxo-1-phenylethyl]piperazin-1-yl}-3-fluorophenyl)-2-pyridin-3-ylbenzamide, a selective brain penet... von SHOBLOCK, James R, WELTY, Natalie, ATACK, John R, DVORAK, Lisa, SWANSON, Devin M, CARRUTHERS, Nicholas I, DVORAK, Curt, LOVENBERG, Timothy W, BONAVENTURE, Pascal, NEPOMUCENO, Diane, LORD, Brian, ALUISIO, Leah, FRASER, Ian, TIMOTHY MOTLEY, S, SUTTON, Steve W, MORTON, Kirsten, GALICI, Ruggero

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Novel substituted pyrrolidines are high affinity histamine H 3 receptor antagonists von Stocking, Emily M., Aluisio, Leah, Atack, John R., Bonaventure, Pascal, Carruthers, Nicholas I., Dugovic, Christine, Everson, Anita, Fraser, Ian, Jiang, Xiaohui, Leung, Perry, Lord, Brian, Ly, Kiev S., Morton, Kirsten L., Nepomuceno, Diane, Shah, Chandravadan R., Shelton, Jonathan, Soyode-Johnson, Akinola, Letavic, Michael A.

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Synthesis and Pharmacological Characterization of Two Novel, Brain Penetrating P2X 7 Antagonists von Letavic, Michael A., Lord, Brian, Bischoff, Francois, Hawryluk, Natalie A., Pieters, Serge, Rech, Jason C., Sales, Zachary, Velter, Adriana I., Ao, Hong, Bonaventure, Pascal, Contreras, Victor, Jiang, Xiaohui, Morton, Kirsten L., Scott, Brian, Wang, Qi, Wickenden, Alan D., Carruthers, Nicholas I., Bhattacharya, Anindya

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Pre-clinical characterization of aryloxypyridine amides as histamine H sub(3) receptor antagonists: Identification of candidates for clinical development von Letavic, Michael A, Aluisio, Leah, Atack, John R, Bonaventure, Pascal, Carruthers, Nicholas I, Dugovic, Christine, Everson, Anita, Feinstein, Mark A, Fraser, Ian C, Hoey, Kenway, Jiang, Xiaohui, Keith, John M, Koudriakova, Tatiana, Leung, Perry, Lord, Brian, Lovenberg, Timothy W, Ly, Kiev S, Morton, Kirsten L, Motley, STimothy, Nepomuceno, Diane, Rizzolio, Michele, Rynberg, Raymond, Sepassi, Kia, Shelton, Jonathan

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Novel substituted pyrrolidines are high affinity histamine H sub(3) receptor antagonists von Stocking, Emily M, Aluisio, Leah, Atack, John R, Bonaventure, Pascal, Carruthers, Nicholas I, Dugovic, Christine, Everson, Anita, Fraser, Ian, Jiang, Xiaohui, Leung, Perry, Lord, Brian, Ly, Kiev S, Morton, Kirsten L, Nepomuceno, Diane, Shah, Chandravadan R, Shelton, Jonathan, Soyode-Johnson, Akinola, Letavic, Michael A

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