Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator von Collibee, Scott E, Bergnes, Gustave, Muci, Alexander, Browne, William F, Garard, Marc, Hinken, Aaron C, Russell, Alan J, Suehiro, Ion, Hartman, James, Kawas, Raja, Lu, Pu-Ping, Lee, Kenneth H, Marquez, David, Tomlinson, Matthew, Xu, Donghong, Kennedy, Adam, Hwee, Darren, Schaletzky, Julia, Leung, Kwan, Malik, Fady I, Morgans, David J, Morgan, Bradley P

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Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure von Malik, Fady I., Hartman, James J., Elias, Kathleen A., Morgan, Bradley P., Rodriguez, Hector, Brejc, Katjuša, Anderson, Robert L., Sueoka, Sandra H., Lee, Kenneth H., Finer, Jeffrey T., Sakowicz, Roman, Baliga, Ramesh, Cox, David R., Garard, Marc, Godinez, Guillermo, Kawas, Raja, Kraynack, Erica, Lenzi, David, Lu, Pu Ping, Muci, Alexander, Niu, Congrong, Qian, Xiangping, Pierce, Daniel W., Pokrovskii, Maria, Suehiro, Ion, Sylvester, Sheila, Tochimoto, Todd, Valdez, Corey, Wang, Wenyue, Katori, Tatsuo, Kass, David A., Shen, You-Tang, Vatner, Stephen F., Morgans, David J.

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Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases von Russell, Alan J, Hartman, James J, Hinken, Aaron C, Muci, Alexander R, Kawas, Raja, Driscoll, Lena, Godinez, Guillermo, Lee, Kenneth H, Marquez, David, Browne, William F, Chen, Michael M, Clarke, David, Collibee, Scott E, Garard, Marc, Hansen, Richard, Jia, Zhiheng, Lu, Pu-Ping, Rodriguez, Hector, Saikali, Khalil G, Schaletzky, Julia, Vijayakumar, Vipin, Albertus, Daniel L, Claflin, Dennis R, Morgans, David J, Morgan, Bradley P, Malik, Fady I

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Tirasemtiv amplifies skeletal muscle response to nerve activation in humans von Hansen, Richard, Saikali, Khalil G., Chou, Willis, Russell, Alan J., Chen, Michael M., Vijayakumar, Vipin, Stoltz, Randall R., Baudry, Stephane, Enoka, Roger M., Morgans, David J., Wolff, Andrew A., Malik, Fady I.

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Leading the way to the next generation of anti-mitotics von Wood, Kenneth W, Jackson, Jeffrey R, Morgans, David J, Elliott, John D, Sabry, James H, Huang, Pearl S

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Asymmetric Synthesis and Stereochemical Assignment of RS-97613, a Potent Immunosuppressive and Antiinflammatory Agent von Smith, David B, Waltos, Ann Marie, Loughhead, David G, Weikert, Robert J, Morgans, David J, Rohloff, John C, Link, John O, Zhu, Rong-rong

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Pharmacology of small molecule inhibitors of GYS1 in a mouse model of Pompe disease von Xi, Yannan, Satterfield, Terrence F., Choy, Rebeca, Gujral, Tarunmeet, Situ, Eva, Tep, Samnang, Morton, Vivian, Yu, Cecile, Reiton, Daniel, Lin, Baiwei, Merritt, Hanne, Santiago, Pam, Espanol, Bryan, Dick, Ryan A., Ullman, Julie C., Mellem, Kevin T., Noonberg, Sarah B., Green, Eric M., Morgans, David J., Chandriani, Sanjay J., Beattie, David T.

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Dual inhibition of α v β 6 and α v β 1 reduces fibrogenesis in lung tissue explants from patients with IPF von Decaris, Martin L, Schaub, Johanna R, Chen, Chun, Cha, Jacob, Lee, Gail G, Rexhepaj, Megi, Ho, Steve S, Rao, Vikram, Marlow, Megan M, Kotak, Prerna, Budi, Erine H, Hooi, Lisa, Wu, Jianfeng, Fridlib, Marina, Martin, Shamra P, Huang, Shaoyi, Chen, Ming, Muñoz, Manuel, Hom, Timothy F, Wolters, Paul J, Desai, Tushar J, Rock, Fernando, Leftheris, Katerina, Morgans, David J, Lepist, Eve-Irene, Andre, Patrick, Lefebvre, Eric A, Turner, Scott M

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Characterization of a Long Acting Smooth Muscle Myosin Inhibitor, CK‐2125927, as a Novel Therapeutic Mechanism for Bronchodilation von Pannirselvam, Malar, Jia, Zhiheng, Durham, Nickie, Zavodovskaya, Marianna, Lenzi, David, Clancy, Sheila, Hartman, James J, Morgans, David J, Morgan, Bradley P, Qian, Xiangping, Malik, Fady I

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Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295 von Qian, Xiangping, McDonald, Andrew, Zhou, Han-Jie, Adams, Nicholas D, Parrish, Cynthia A, Duffy, Kevin J, Fitch, Duke M, Tedesco, Rosanna, Ashcraft, Luke W, Yao, Bing, Jiang, Hong, Huang, Jennifer K, Marin, Melchor V, Aroyan, Carrie E, Wang, Jianchao, Ahmed, Seyed, Burgess, Joelle L, Chaudhari, Amita M, Donatelli, Carla A, Darcy, Michael G, Ridgers, Lance H, Newlander, Ken A, Schmidt, Stanley J, Chai, Deping, Colón, Mariela, Zimmerman, Michael N, Lad, Latesh, Sakowicz, Roman, Schauer, Stephen, Belmont, Lisa, Baliga, Ramesh, Pierce, Daniel W, Finer, Jeffrey T, Wang, Zhengping, Morgan, Bradley P, Morgans, David J, Auger, Kurt R, Sung, Chiu-Mei, Carson, Jeff D, Luo, Lusong, Hugger, Erin D, Copeland, Robert A, Sutton, David, Elliott, John D, Jackson, Jeffrey R, Wood, Kenneth W, Dhanak, Dashyant, Bergnes, Gustave, Knight, Steven D

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Abstract 5077: Inhibition of Smooth Muscle Myosin, a Novel Anti-Hypertensive Strategy von Shen, You-Tang, Chen, Li, Zhao, Xin, Qian, Xiangping, Morgans, David J, Vatner, Stephen F, Malik, Fady I

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Selective Inhibition of Prostaglandin Endoperoxide Synthase-1 (Cyclooxygenase-1) by Valerylsalicylic Acid von Bhattacharyya, D.K., Lecomte, M., Dunn, J., Morgans, D.J., Smith, W.L.

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QUINAZOLINONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM von FENG, BAINIAN, JR. MORGANS, DAVID J, BERGNES, GUSTAV, CHABALA, JOHN C, FINER, JEFFREY T, SMITH, WHITNEY W

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AMINO ACID COMPOUNDS AND METHODS OF USE von CHA, Jacob, DONG, Chengguo, HOM, Timothy, LI, Hui, REILLY, Maureen, BAILEY, Christopher, MORGANS, David J, LEFTHERIS, Katerina, JIANG, Lan, MUNOZ, Manuel, ZHENG, Yajun, FINKELSTEIN, Darren

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In Vitro and In Vivo Characterization of CK-1827452, a Selective Cardiac Myosin Activator von Anderson, Robert L., Sueoka, Sandra H., Lee, Kenneth H., Rodriguez, Hector M., Kawas, Raja F., Godinez, Guillermo, Morgan, Bradley P., Sakowicz, Roman, Morgans, David J., Malik, Fady, Elias, Kathleen A.

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Cardiac Myosin Activator CK-1316719 Increases MyoFibril ATPase Activity and Myocyte Contractility in a Rat Model of Heart Failure von Anderson, Robert L., Kawas, Raja F., Pokrovskii, Maria V., Godinez, Guillermo, Lee, Kenneth H., Mak, John, Morgan, Bradley P., Morgans, David J., Malik, Fady, Sakowicz, Roman, Elias, Kathleen A.

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AMINO ACID COMPOUNDS AND METHODS OF USE von KATERINA LEFTHERIS, YAJUN ZHENG, BAILEY, Christopher, JACOB CHA, HUI LI, DAVID J MORGANS JR, MANUEL MUNOZ, MAUREEN REILLY, TIMOTHY HOM, CHENGGUO DONG, FINKELSTEIN, Darren, LAN JIANG

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The Florisil ® catalyzed [1,3]-sigmatropic shift of allyl phenyl ethers — An entryway into novel mycophenolic acid analogues von Talamás, Francisco X., Smith, David B., Cervantes, Alicia, Franco, Fidencio, Cutler, Serena T., Loughhead, David G., Morgans, David J., Weikert, Robert J.

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CERTAIN CHEMICAL ENTITIES COMPRISING IMIDAZOPYRIMIDINES, COMPOSITIONS AND METHODS von MUCI, Alex, RUSSELL, Alan James, LU, Pu-Ping, MORGAN, Bradley P, FINER, Jeffrey T, MORGANS, David J., Jr

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Compuestos de aminoácidos y métodos de uso von Katerina LEFTHERIS, Manuel MUÑOZ, Timothy HOM, Yahun ZHENG, Maureen REILLY, Nicole COOPER, David J. MORGANS JR, Jacob CHA

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