Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK) von MacKinnon, Colin H., Lau, Kevin, Burch, Jason D., Chen, Yuan, Dines, Jonathon, Ding, Xiao, Eigenbrot, Charles, Heifetz, Alexander, Jaochico, Allan, Johnson, Adam, Kraemer, Joachim, Kruger, Susanne, Krülle, Thomas M., Liimatta, Marya, Ly, Justin, Maghames, Rosemary, Montalbetti, Christian A.G.N., Ortwine, Daniel F., Pérez-Fuertes, Yolanda, Shia, Steven, Stein, Daniel B., Trani, Giancarlo, Vaidya, Darshan G., Wang, Xiaolu, Bromidge, Steven M., Wu, Lawren C., Pei, Zhonghua

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Design, synthesis and structure-activity relationships of a novel class of sulfonylpyridine inhibitors of Interleukin-2 inducible T-cell kinase (ITK) von Trani, Giancarlo, Barker, John J, Bromidge, Steven M, Brookfield, Frederick A, Burch, Jason D, Chen, Yuan, Eigenbrot, Charles, Heifetz, Alexander, Ismaili, M Hicham A, Johnson, Adam, Krülle, Thomas M, MacKinnon, Colin H, Maghames, Rosemary, McEwan, Paul A, Montalbetti, Christian A G N, Ortwine, Daniel F, Pérez-Fuertes, Yolanda, Vaidya, Darshan G, Wang, Xiaolu, Zarrin, Ali A, Pei, Zhonghua

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The synthesis and evaluation of indolylureas as PKCα inhibitors von Djung, Jane F., Mears, Richard. J., Montalbetti, Christian A.G.N., Coulter, Thomas S., Golebiowski, Adam, Carr, Andrew N., Barker, Oliver, Greis, Kenneth D., Zhou, Songtao, Dolan, Elizabeth, Davis, Gregory F.

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Amide bond formation and peptide coupling von Montalbetti, Christian A.G.N., Falque, Virginie

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Discovery of a Novel Hsp90 Inhibitor by Fragment Linking von Barker, John J., Barker, Oliver, Courtney, Stephen M., Gardiner, Mihaly, Hesterkamp, Thomas, Ichihara, Osamu, Mather, Owen, Montalbetti, Christian A. G. N., Müller, Annett, Varasi, Mario, Whittaker, Mark, Yarnold, Christopher J.

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HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives von Wang, Guangyi, Lei, Huoxing, Wang, Xiaofang, Das, Debasis, Hong, Jian, Mackinnon, Colin H., Coulter, Thomas S., Montalbetti, Christian A.G.N., Mears, Richard, Gai, Xinjie, Bailey, Sarah E., Ruhrmund, Donald, Hooi, Lisa, Misialek, Shawn, Rajagopalan, P.T. Ravi, Cheng, Robert K.Y., Barker, John J., Felicetti, Brunella, Schönfeld, Dorian L., Stoycheva, Antitsa, Buckman, Brad O., Kossen, Karl, Seiwert, Scott D., Beigelman, Leonid

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Fragment‐based Identification of Hsp90 Inhibitors von Barker, John J., Barker, Oliver, Boggio, Roberto, Chauhan, Viddhata, Cheng, Robert K. Y., Corden, Vincent, Courtney, Stephen M., Edwards, Neil, Falque, Virginie M., Fusar, Fulvia, Gardiner, Mihaly, Hamelin, Estelle M. N., Hesterkamp, Thomas, Ichihara, Osamu, Jones, Richard S., Mather, Owen, Mercurio, Ciro, Minucci, Saverio, Montalbetti, Christian A. G. N., Müller, Annett, Patel, Deepti, Phillips, Banu G., Varasi, Mario, Whittaker, Mark, Winkler, Dirk, Yarnold, Christopher J.

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C–H Halogenation of Pyridyl Sulfides Avoiding the Sulfur Oxidation: A Direct Catalytic Access to Sulfanyl Polyhalides and Polyaromatics von Guilbaud, Johan, Selmi, Awatef, Kammoun, Majed, Contal, Sylvie, Montalbetti, Christian, Pirio, Nadine, Roger, Julien, Hierso, Jean-Cyrille

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Chiral Resolution and Pharmacological Characterization of the Enantiomers of the Hsp90 Inhibitor 2-Amino-7-[4-fluoro-2-(3-pyridyl)phenyl]-4-methyl-7,8-dihydro-6H-quinazolin-5-one O... von Amici, Raffaella, Bigogno, Chiara, Boggio, Roberto, Colombo, Andrea, Courtney, Stephen M., Dal Zuffo, Roberto, Dondio, Giulio, Fusar, Fulvia, Gagliardi, Stefania, Minucci, Saverio, Molteni, Marco, Montalbetti, Christian A. G. N., Mortoni, Annalisa, Varasi, Mario, Vultaggio, Stefania, Mercurio, Ciro

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Syntheses and antiproliferative evaluation of oxyphenisatin derivatives von Uddin, Muhammed K., Reignier, Serge G., Coulter, Tom, Montalbetti, Christian, Grånäs, Charlotta, Butcher, Steven, Krog-Jensen, Christian, Felding, Jakob

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Investigation of a New Family of Chiral Ligands for Enantioselective Catalysis via Parallel Synthesis and High-Throughput Screening von Gennari, Cesare, Ceccarelli, Simona, Piarulli, Umberto, Montalbetti, Christian A. G. N, Jackson, Richard F. W

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Azide-free synthesis of Boc-protected (3R,4S)-3,4-dihydroxypiperidine von Fezzardi, Paola, Fabbrini, Danilo, Relitti, Nicola, Ferrigno, Federica, Rossetti, Ilaria, Sferrazza, Alessio, Petrocchi, Alessia, Montalbetti, Christian

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Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR) α/γ/δ Triple Activators: Discovery of Lanifibranor, a Ne... von Boubia, Benaïssa, Poupardin, Olivia, Barth, Martine, Binet, Jean, Peralba, Philippe, Mounier, Laurent, Jacquier, Elise, Gauthier, Emilie, Lepais, Valérie, Chatar, Maryline, Ferry, Stéphanie, Thourigny, Anne, Guillier, Fabrice, Llacer, Jonathan, Amaudrut, Jérome, Dodey, Pierre, Lacombe, Olivier, Masson, Philippe, Montalbetti, Christian, Wettstein, Guillaume, Luccarini, Jean-Michel, Legendre, Christiane, Junien, Jean-Louis, Broqua, Pierre

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Synthetic strategies to prepare 2-alkyl, 2-aryl and 2-acetylenyl substituted 4,6-diamino-1,3,5-triazines von Montalbetti, Christian A.G.N., Coulter, Thomas S., Uddin, Muhammed K., Reignier, Serge G., Magaraci, Filippo, Grånäs, Charlotta, Krog-Jensen, Christian, Felding, Jakob

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SAR evolution towards potent C-terminal carboxamide peptide inhibitors of Zika virus NS2B-NS3 protease von Colarusso, Stefania, Ferrigno, Federica, Ponzi, Simona, Pavone, Francesca, Conte, Immacolata, Abate, Luigi, Beghetto, Elisa, Missineo, Antonino, Amaudrut, Jerome, Bresciani, Alberto, Paonessa, Giacomo, Tomei, Licia, Montalbetti, Christian, Bianchi, Elisabetta, Toniatti, Carlo, Ontoria, Jesus M.

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Discovery of a Novel Series of Potent SHP2 Allosteric Inhibitors von Petrocchi, Alessia, Grillo, Alessandro, Ferrante, Luca, Randazzo, Pietro, Prandi, Adolfo, De Matteo, Marilenia, Iaccarino, Costanza, Bisbocci, Monica, Cellucci, Antonella, Alli, Cristina, Nibbio, Martina, Pucci, Vincenzo, Amaudrut, Jérôme, Montalbetti, Christian, Toniatti, Carlo, Di Fabio, Romano

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(2‐Pyridyl)sulfonyl Groups for ortho‐Directing Palladium‐ Catalyzed Carbon–Halogen Bond Formation at Functionalized Arenes von Guilbaud, Johan, Labonde, Marine, Cattey, Hélène, Contal, Sylvie, Montalbetti, Christian, Pirio, Nadine, Roger, Julien, Hierso, Jean‐Cyrille

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Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K) von Castanedo, Georgette M, Blaquiere, Nicole, Beresini, Maureen, Bravo, Brandon, Brightbill, Hans, Chen, Jacob, Cui, Hai-Feng, Eigenbrot, Charles, Everett, Christine, Feng, Jianwen, Godemann, Robert, Gogol, Emily, Hymowitz, Sarah, Johnson, Adam, Kayagaki, Nobuhiko, Kohli, Pawan Bir, Knüppel, Kathleen, Kraemer, Joachim, Krüger, Susan, Loke, Pui, McEwan, Paul, Montalbetti, Christian, Roberts, David A, Smith, Myron, Steinbacher, Stefan, Sujatha-Bhaskar, Swathi, Takahashi, Ryan, Wang, Xiaolu, Wu, Lawren C, Zhang, Yamin, Staben, Steven T

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N-(2-pyridyl)sulfonyl groups for ortho-directing palladium carbon-halogen bond formation at functionalized arenes von Guilbaud, Johan, Labonde, Marine, Cattey, Hélène, Contal, Sylvie, Montalbetti, Christian, Pirio, Nadine, Roger, Julien, Hierso, Jean-Cyrille

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Abstract 99: Identification of G9a inhibitors by AlphaLisa™ technology and hit confirmation using MT-Glo von Fromond, Claudia, Espanel, Xavier, Chene, Laurent, Masson, Philippe, Boubia, Benaïssa, Montalbetti, Christian, Broqua, Pierre

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