Pomalidomide shows significant therapeutic activity against CNS lymphoma with a major impact on the tumor microenvironment in murine models von Li, Zhimin, Qiu, Yushi, Personett, David, Huang, Peng, Edenfield, Brandy, Katz, Jason, Babusis, Darius, Tang, Yang, Shirely, Michael A, Moghaddam, Mehran F, Copland, John A, Tun, Han W

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Isosteric analogs of lenalidomide and pomalidomide: Synthesis and biological activity von Ruchelman, Alexander L., Man, Hon-Wah, Zhang, Weihong, Chen, Roger, Capone, Lori, Kang, Jian, Parton, Anastasia, Corral, Laura, Schafer, Peter H., Babusis, Darius, Moghaddam, Mehran F., Tang, Yang, Shirley, Michael A., Muller, George W.

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Discovery of the c‑Jun N‑Terminal Kinase Inhibitor CC-90001 von Nagy, Mark A, Hilgraf, Robert, Mortensen, Deborah S, Elsner, Jan, Norris, Stephen, Tikhe, Jayashree, Yoon, Won, Paisner, David, Delgado, Mercedes, Erdman, Paul, Haelewyn, Jason, Khambatta, Godrej, Xu, Li, Romanow, William J, Condroski, Kevin, Bahmanyar, Sogole, McCarrick, Meg, Benish, Brent, Blease, Kate, LeBrun, Laurie, Moghaddam, Mehran F, Apuy, Julius, Canan, Stacie S, Bennett, Brydon L, Satoh, Yoshitaka

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The Discovery of a Dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) Inhibitor for the Treatment of Triple Negative Breast Cancer Initiated from a Phenotypic Screen von Riggs, Jennifer R, Nagy, Mark, Elsner, Jan, Erdman, Paul, Cashion, Dan, Robinson, Dale, Harris, Roy, Huang, Dehua, Tehrani, Lida, Deyanat-Yazdi, Gordafaried, Narla, Rama Krishna, Peng, Xiaohui, Tran, Tam, Barnes, Leo, Miller, Terra, Katz, Jason, Tang, Yang, Chen, Ming, Moghaddam, Mehran F, Bahmanyar, Sogole, Pagarigan, Barbra, Delker, Silvia, LeBrun, Laurie, Chamberlain, Philip P, Calabrese, Andrew, Canan, Stacie S, Leftheris, Katerina, Zhu, Dan, Boylan, John F

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Optimization of a Series of Triazole Containing Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors and the Discovery of CC-115 von Mortensen, Deborah S., Perrin-Ninkovic, Sophie M., Shevlin, Graziella, Elsner, Jan, Zhao, Jingjing, Whitefield, Brandon, Tehrani, Lida, Sapienza, John, Riggs, Jennifer R., Parnes, Jason S., Papa, Patrick, Packard, Garrick, Lee, Branden G.S., Harris, Roy, Correa, Matthew, Bahmanyar, Sogole, Richardson, Samantha J., Peng, Sophie X., Leisten, Jim, Khambatta, Godrej, Hickman, Matt, Gamez, James C., Bisonette, René R., Apuy, Julius, Cathers, Brian E., Canan, Stacie S., Moghaddam, Mehran F., Raymon, Heather K., Worland, Peter, Narla, Rama Krishna, Fultz, Kimberly E., Sankar, Sabita

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CC-223, a Potent and Selective Inhibitor of mTOR Kinase: In Vitro and In Vivo Characterization von Mortensen, Deborah S, Fultz, Kimberly E, Xu, Shuichan, Xu, Weiming, Packard, Garrick, Khambatta, Godrej, Gamez, James C, Leisten, Jim, Zhao, Jingjing, Apuy, Julius, Ghoreishi, Kamran, Hickman, Matt, Narla, Rama Krishna, Bissonette, Rene, Richardson, Samantha, Peng, Sophie X, Perrin-Ninkovic, Sophie, Tran, Tam, Shi, Tao, Yang, Wen Qing, Tong, Zeen, Cathers, Brian E, Moghaddam, Mehran F, Canan, Stacie S, Worland, Peter, Sankar, Sabita, Raymon, Heather K

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Discovery of Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor CC-223 von Mortensen, Deborah S, Perrin-Ninkovic, Sophie M, Shevlin, Graziella, Zhao, Jingjing, Packard, Garrick, Bahmanyar, Sogole, Correa, Matthew, Elsner, Jan, Harris, Roy, Lee, Branden G. S, Papa, Patrick, Parnes, Jason S, Riggs, Jennifer R, Sapienza, John, Tehrani, Lida, Whitefield, Brandon, Apuy, Julius, Bisonette, René R, Gamez, James C, Hickman, Matt, Khambatta, Godrej, Leisten, Jim, Peng, Sophie X, Richardson, Samantha J, Cathers, Brian E, Canan, Stacie S, Moghaddam, Mehran F, Raymon, Heather K, Worland, Peter, Narla, Rama Krishna, Fultz, Kimberly E, Sankar, Sabita

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Implementation of a novel ultra fast metabolic stability analysis method using exact mass TOF-MS von Manna, Joseph D, Richardson, Samantha J, Moghaddam, Mehran F

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Cell-Free Biosynthesis and Source of Hydroxyl Groups in (12R, 13S)-Dihydroxy-(5Z,8Z, 10E, 14Z)-Eicosatetraenoic Acid, a Novel Eicosanoid from the Marine Alga Gracilariopsis lemanei... von Moghaddam, Mehran F, Gerwick, William H

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An LC/MS/MS Method for Improved Quantitation of the Bound Residues in the Tissues of Animals Orally Dosed with [14C]Benomyl von Moghaddam, Mehran F, Trubey, Richard K, Anderson, Jeffrey J

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Bioactivation of leukotoxins to their toxic diols by epoxide hydrolase von Moghaddam, Mehran F., Grant, David F., Cheek, Jeffrey M., Greene, Jessica F., Williamson, Kristin C., Hammock, Bruce D.

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DUAL INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE AND METHODS OF USE THEREOF von MOGHADDAM, Mehran F

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DUAL INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE AND METHODS OF USE THEREOF von MOGHADDAM, Mehran F

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Gloiosiphones A and B, Novel Metabolites from the Red Marine Alga Gloiosiphonia verticillaris von Chen, Jian Lu, Moghaddam, Mehran F, Gerwick, William H

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Pomalidomide Shows Significant Therapeutic Activity against CNS Lymphoma with a Major Impact on the Tumor Microenvironment in Murine Models. e71754 von Li, Zhimin, Qiu, Yushi, Personett, David, Huang, Peng, Edenfield, Brandy, Katz, Jason, Babusis, Darius, Tang, Yang, Shirely, Michael A, Moghaddam, Mehran F

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Novel metabolic pathways for linoleic and arachidonic acid metabolism von Moghaddam, Mehran F., Motoba, Kazuhiko, Borhan, Babak, Pinot, Franck, Hammock, Bruce D.

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Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith von Delgado, Mercedes, Sloss, Marianne, Norris, Stephen, Paisner, David A, Elsner, Jan, McCarrick, Meg, Satoh, Yoshitaka, Bennett, Brydon L, LeBrun, Laurie Ann, Moghaddam, Mehran F, Nagy, Mark A, Yoon, Won Hyung, Tikhe, Jayashree, Erdman, Paul, Romanow, William J, Hilgraf, Robert

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SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH von YOON, WON, HYUNG, TIKHE, JAYASHREE, DELGADO, MARIA MERCEDES, MOGHADDAM, MEHRAN, F, MCCARRICK, MEG, SATOH, YOSHITAKA, SLOSS, MARIANNE, ELSNER, JAN, HILGRAF, ROBERT, NAGY, MARK, A, NORRIS, STEPHEN, LEBRUN, LAURIE, ANN, PAISNER, DAVID, A, BENNETT, BRYDON, L, ERDMAN, PAUL, ROMANOW, WILLIAM, J

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SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH von MOGHADDAM Mehran F, SLOSS Marianne, HILGRAF Robert, TIKHE Jayashree, MCCARRICK Meg, NORRIS Stephen, ELSNER Jan, ERDMAN Paul, YOON Won Hyung, LEBRUN Laurie Ann, DELGADO Maria Mercedes, NAGY Mark A, SATOH Yoshitaka, PAISNER David A, ROMANOW William J, BENNETT Brydon L

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SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH von Mccarrick, Meg, Delgado, Maria Mercedes, Lebrun, Laurie Ann, Sloss, Marianne, Norris, Stephen, Paisner, David A, Elsner, Jan, Satoh, Yoshitaka, Bennett, Brydon L, Moghaddam, Mehran F, Nagy, Mark A, Yoon, Won Hyung, Tikhe, Jayashree, Erdman, Paul, Romanow, William J, Hilgraf, Robert

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