Contribution of Relapse-Independent Progression vs Relapse-Associated Worsening to Overall Confirmed Disability Accumulation in Typical Relapsing Multiple Sclerosis in a Pooled Ana... von Kappos, Ludwig, Wolinsky, Jerry S, Giovannoni, Gavin, Arnold, Douglas L, Wang, Qing, Bernasconi, Corrado, Model, Fabian, Koendgen, Harold, Manfrini, Marianna, Belachew, Shibeshih, Hauser, Stephen L

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Chronic white matter lesion activity predicts clinical progression in primary progressive multiple sclerosis von Elliott, Colm, Belachew, Shibeshih, Wolinsky, Jerry S, Hauser, Stephen L, Kappos, Ludwig, Barkhof, Frederik, Bernasconi, Corrado, Fecker, Julian, Model, Fabian, Wei, Wei, Arnold, Douglas L

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Estimating drug concentration–response relationships by applying causal inference methods for continuous point exposures and time-to-event outcomes von Yiu, Sean, Wang, Qing, Mercier, Francois, Manfrini, Marianna, Koendgen, Harold, Kletzl, Heidemarie, Model, Fabian

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DNA Methylation Biomarkers for Blood-Based Colorectal Cancer Screening von Lofton-Day, Catherine, Model, Fabian, DeVos, Theo, Tetzner, Reimo, Distler, Juergen, Schuster, Matthias, Song, Xiaoling, Lesche, Ralf, Liebenberg, Volker, Ebert, Matthias, Molnar, Bela, Grutzmann, Robert, Pilarsky, Christian, Sledziewski, Andrew

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Circulating Methylated SEPT9 DNA in Plasma Is a Biomarker for Colorectal Cancer von deVos, Theo, Tetzner, Reimo, Model, Fabian, Weiss, Gunter, Schuster, Matthias, Distler, Jurgen, Steiger, Kathryn V, Grutzmann, Robert, Pilarsky, Christian, Habermann, Jens K, Fleshner, Phillip R, Oubre, Benton M, Day, Robert, Sledziewski, Andrew Z, Lofton-Day, Catherine

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Recurrent disability progression endpoints in multiple sclerosis clinical trials von Bühler, Alexandra, Wolbers, Marcel, Model, Fabian, Wang, Qing, Belachew, Shibeshih, Manfrini, Marianna, Lorscheider, Johannes, Kappos, Ludwig, Beyersmann, Jan

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Sensitive detection of colorectal cancer in peripheral blood by septin 9 DNA methylation assay von Grützmann, Robert, Molnar, Bela, Pilarsky, Christian, Habermann, Jens K, Schlag, Peter M, Saeger, Hans D, Miehlke, Stephan, Stolz, Thomas, Model, Fabian, Roblick, Uwe J, Bruch, Hans-Peter, Koch, Rainer, Liebenberg, Volker, Devos, Theo, Song, Xiaoling, Day, Robert H, Sledziewski, Andrew Z, Lofton-Day, Catherine

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Five-year efficacy outcomes of ocrelizumab in relapsing multiple sclerosis: A propensity-matched comparison of the OPERA studies with other disease-modifying therapies in real-worl... von Muros-Le Rouzic, Erwan, Heer, Yanic, Yiu, Sean, Tozzi, Viola, Braune, Stefan, van Hövell, Philip, Bergmann, Arnfin, Bernasconi, Corrado, Model, Fabian, Craveiro, Licinio

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DNA methylation biomarkers of prostate cancer: Confirmation of candidates and evidence urine is the most sensitive body fluid for non-invasive detection von Payne, Shannon R., Serth, Jűrgen, Schostak, Martin, Kamradt, Jőrn, Strauss, Arne, Thelen, Paul, Model, Fabian, Day, J. Kevin, Liebenberg, Volker, Morotti, Andrew, Yamamura, Su, Lograsso, Joe, Sledziewski, Andrew, Semjonow, Axel

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Ocrelizumab in relapsing and primary progressive multiple sclerosis: Pharmacokinetic and pharmacodynamic analyses of OPERA I, OPERA II and ORATORIO von Gibiansky, Ekaterina, Petry, Claire, Mercier, Francois, Günther, Andreas, Herman, Ann, Kappos, Ludwig, Hauser, Stephen, Yamamoto, Yumi, Wang, Qing, Model, Fabian, Kletzl, Heidemarie

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Five years of ocrelizumab in relapsing multiple sclerosis: OPERA studies open-label extension von Hauser, Stephen L., Kappos, Ludwig, Arnold, Douglas L., Bar-Or, Amit, Brochet, Bruno, Naismith, Robert T., Traboulsee, Anthony, Wolinsky, Jerry S., Belachew, Shibeshih, Koendgen, Harold, Levesque, Victoria, Manfrini, Marianna, Model, Fabian, Hubeaux, Stanislas, Mehta, Lahar, Montalban, Xavier

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DNL310 phase 1/2 case study demonstrates properties of raw, standard and growth scale scores for adaptive behavior scales von Engmann, Natalie J., Scheller, Adam, Caprihan, Rupa, Neitmann, Thomas, Bakardjiev, Anna, Model, Fabian, Ostland, Michael

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Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease von Model, Fabian, Osborn, Neal, Ahlquist, David, Gruetzmann, Robert, Molnar, Bela, Sipos, Ferenc, Galamb, Orsolya, Pilarsky, Christian, Saeger, Hans-Detlev, Tulassay, Zsolt, Hale, Kari, Mooney, Suzanne, Lograsso, Joseph, Adorjan, Peter, Lesche, Ralf, Dessauer, Andreas, Kleiber, Joerg, Porstmann, Baerbel, Sledziewski, Andrew, Lofton-Day, Catherine

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Application of the Parametric g-Formula to Characterizing Counterfactual Time-to-Event Disability Progression Outcomes in Multiple Sclerosis von Yiu, Sean, Wang, Qing, Mercier, Francois, Dahlke, Frank, Model, Fabian

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Evaluation of NEDA as a Predictor of Disease Progression in Patients With RMS and PPMS Treated With Ocrelizumab: Post-Hoc Analyses From the OPERA I/OPERA II and ORATORIO Trials (P1... von Montalban, Xavier, Sormani, Maria Pia, Koendgen, Harold, Model, Fabian, Overell, James, Schneble, Hans-Martin, Wang, Qing, Rotstein, Dalia

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Statistical process control for large scale microarray experiments von Model, Fabian, König, Thomas, Piepenbrock, Christian, Adorján, Péter

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A blinded randomized phase 2/3 study of the efficacy and safety of intravenous DNL310 (brain-penetrant enzyme replacement therapy) in MPS II von Harris, Jeffrey, Zhu, Yuda, Ho, Judy, Chen, Charlene, Bakardjiev, Anna, Model, Fabian, Troyer, Matthew, Ho, Carole, Chin, Peter

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Reduction in 48-Week Confirmed Disability Progression After 5.5 Years of Ocrelizumab Treatment in Patients With Primary Progressive Multiple Sclerosis (P3.2-031) von Wolinsky, Jerry S., Kappos, Ludwig, Montalban, Xavier, Model, Fabian, Mehta, Lahar, Hubeaux, Stanislas, Giovannoni, Gavin

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COMPASS, a double-blinded randomized phase 2/3 study of the efficacy and safety of intravenous DNL310 (brain-penetrant enzyme replacement therapy) in MPS II von Rodriguez, Jose Alcantara, Harris, Jeff, Cygon, Peter, Zhu, Yuda, Engmann, Natalie, Costanzo, Simona, Model, Fabian, Dong, Wei, Ho, Carole, Chin, Peter

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Quantitative DNA Methylation Analysis of FOXP3 as a New Method for Counting Regulatory T Cells in Peripheral Blood and Solid Tissue von WIECZOREK, Georg, ASEMISSEN, Anne, HAMANN, Alf, LODDENKEMPER, Christoph, STEIN, Harald, DIETER VOLK, Hans, HOFFMÜLLER, Ulrich, GRÜTZKAU, Andreas, MUSTEA, Alexander, HUEHN, Jochen, SCHEIBENBOGEN, Carmen, OLEK, Sven, MODEL, Fabian, TURBACHOVA, Ivana, FLOES, Stefan, LIEBENBERG, Volker, BARON, Udo, STAUCH, Diana, KOTSCH, Katja, PRATSCHKE, Johann

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