Impact of Manufacturing Procedures on CAR T Cell Functionality von Watanabe, Norihiro, Mo, Feiyan, McKenna, Mary Kathryn

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Engineered off-the-shelf therapeutic T cells resist host immune rejection von Mo, Feiyan, Watanabe, Norihiro, McKenna, Mary K., Hicks, M. John, Srinivasan, Madhuwanti, Gomes-Silva, Diogo, Atilla, Erden, Smith, Tyler, Ataca Atilla, Pinar, Ma, Royce, Quach, David, Heslop, Helen E., Brenner, Malcolm K., Mamonkin, Maksim

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Efficacy of a Small-Molecule Inhibitor of KrasG12D in Immunocompetent Models of Pancreatic Cancer von Kemp, Samantha B, Cheng, Noah, Markosyan, Nune, Sor, Rina, Kim, Il-Kyu, Hallin, Jill, Shoush, Jason, Quinones, Liz, Brown, Natalie V, Bassett, Jared B, Joshi, Nikhil, Yuan, Salina, Smith, Molly, Vostrejs, William P, Perez-Vale, Kia Z, Kahn, Benjamin, Mo, Feiyan, Donahue, Timothy R, Radu, Caius G, Clendenin, Cynthia, Christensen, James G, Vonderheide, Robert H, Stanger, Ben Z

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Modulating TNFα activity allows transgenic IL15-Expressing CLL-1 CAR T cells to safely eliminate acute myeloid leukemia von Ataca Atilla, Pinar, McKenna, Mary K, Tashiro, Haruko, Srinivasan, Madhuwanti, Mo, Feiyan, Watanabe, Norihiro, Simons, Brian Wesley, McLean Stevens, Alexandra, Redell, Michele S, Heslop, Helen E, Mamonkin, Maksim, Brenner, Malcolm K, Atilla, Erden

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Generation of Chimeric Antigen Receptor T Cells Using Gammaretroviral Vectors von Mo, Feiyan, Mamonkin, Maksim

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Taking T-Cell Oncotherapy Off-the-Shelf von Mo, Feiyan, Mamonkin, Maksim, Brenner, Malcolm K., Heslop, Helen E.

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Apoptosis of Hematopoietic Stem Cells Contributes to Bone Marrow Suppression Following CAR-T Therapy von Read, Jay A., Mo, Feiyan, Mamonkin, Maksim, Rouce, Rayne H., King, Katherine Y.

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Engineering T cells to prevent graft-versus-host disease and leukemia relapse following allogeneic stem cell transplantation von Mo, Feiyan, Watanabe, Norihiro, Burkhardt, Phillip M, Heslop, Helen E, Brenner, Malcolm K, Mamonkin, Maksim

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CD7 CAR T Cells for the Therapy of Acute Myeloid Leukemia von Gomes-Silva, Diogo, Atilla, Erden, Atilla, Pinar Ataca, Mo, Feiyan, Tashiro, Haruko, Srinivasan, Madhuwanti, Lulla, Premal, Rouce, Rayne H., Cabral, Joaquim M.S., Ramos, Carlos A., Brenner, Malcolm K., Mamonkin, Maksim

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CRISPR-Edited Immune Effectors: The End of the Beginning von Mo, Feiyan, Heslop, Helen E., Mamonkin, Maksim

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Feasibility and preclinical efficacy of CD7-unedited CD7 CAR T cells for T cell malignancies von Watanabe, Norihiro, Mo, Feiyan, Zheng, Rong, Ma, Royce, Bray, Vanesa C., van Leeuwen, Dayenne G., Sritabal-Ramirez, Juntima, Hu, Hongxiang, Wang, Sha, Mehta, Birju, Srinivasan, Madhuwanti, Scherer, Lauren D., Zhang, Huimin, Thakkar, Sachin G., Hill, LaQuisa C., Heslop, Helen E., Cheng, Chonghui, Brenner, Malcolm K., Mamonkin, Maksim

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Reversible Transgene Expression Reduces Fratricide and Permits 4-1BB Costimulation of CAR T Cells Directed to T-cell Malignancies von Mamonkin, Maksim, Mukherjee, Malini, Srinivasan, Madhuwanti, Sharma, Sandhya, Gomes-Silva, Diogo, Mo, Feiyan, Krenciute, Giedre, Orange, Jordan S, Brenner, Malcolm K

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Repurposing potential of 1st generation H 1 -specific antihistamines as anti-filovirus therapeutics von Schafer, Adam, Cheng, Han, Xiong, Rui, Soloveva, Veronica, Retterer, Cary, Mo, Feiyan, Bavari, Sina, Thatcher, Gregory, Rong, Lijun

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Human platelet lysate enhances in vivo activity of CAR-Vδ2 T cells by reducing cellular senescence and apoptosis von Mo, Feiyan, Tsai, Chiou-Tsun, Zheng, Rong, Cheng, Chonghui, Heslop, Helen E., Brenner, Malcolm K., Mamonkin, Maksim, Watanabe, Norihiro

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Engineering T cells to suppress acute GVHD and leukemia relapse after allogeneic hematopoietic stem cell transplantation von Mo, Feiyan, Watanabe, Norihiro, Omdahl, Kayleigh I., Burkhardt, Phillip M., Ding, Xiaoyun, Hayase, Eiko, Panoskaltsis-Mortari, Angela, Jenq, Robert R., Heslop, Helen E., Kean, Leslie S., Brenner, Malcolm K., Tkachev, Victor, Mamonkin, Maksim

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Repurposing potential of 1st generation H1-specific antihistamines as anti-filovirus therapeutics von Schafer, Adam, Cheng, Han, Xiong, Rui, Soloveva, Veronica, Retterer, Cary, Mo, Feiyan, Bavari, Sina, Thatcher, Gregory, Rong, Lijun

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Apoptosis of HSCs contributes to bone marrow suppression following CAR-T therapy von Read, Jay A., Rouce, Rayne H., Mo, Feiyan, Mamonkin, Maksim, King, Katherine Y.

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Rejection-resistant off-the-shelf T cells for adoptive cell therapy von Mo, Feiyan, Srinivasan, Madhuwanti, Ma, Royce, Smith, Tyler S, McKenna, Mary K, Atilla, Erden, Atilla, Pinar Ataca, Heslop, Helen E, Brenner, Malcolm K, Mamonkin, Maksim

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Apoptosis of Hematopoietic Stem Cells Contributes to Bone Marrow Suppression Following Chimeric Antigen Receptor T Cell Therapy von Read, Jay A., Rouce, Rayne H., Mo, Feiyan, Mamonkin, Maksim, King, Katherine Y.

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Abstract A014: Inhibition of KrasG12D with a novel small molecule inhibitor alters the pancreatic cancer microenvironment von Kemp, Samantha B., Cheng, Noah, Markosyan, Nune, Sor, Rina, Kim, Il-Kyu, Hallin, Jill, Shoush, Jason, Quinones, Liz, Brown, Natalie, Bassett, Jared B., Joshi, Nikhil, Yuan, Salina, Smith, Molly, Vostrejs, William P., Perez-Vale, Kia Z., Kahn, Benjamin, Mo, Feiyan, Donahue, Timothy R., Radu, Caius G., Clendenin, Cynthia, Christensen, James G., Vonderheide, Robert H., Stanger, Ben Z.

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