Genome-wide chromatin contacts of super-enhancer-associated lncRNA identify LINC01013 as a regulator of fibrosis in the aortic valve von Chignon, Arnaud, Argaud, Déborah, Boulanger, Marie-Chloé, Mkannez, Ghada, Bon-Baret, Valentin, Li, Zhonglin, Thériault, Sébastien, Bossé, Yohan, Mathieu, Patrick

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Manganese Induces Oxidative Stress, Redox State Unbalance and Disrupts Membrane Bound ATPases on Murine Neuroblastoma Cells In Vitro: Protective Role of Silymarin von Chtourou, Yassine, Trabelsi, Khaled, Fetoui, Hamadi, Mkannez, Ghada, Kallel, Héla, Zeghal, Najiba

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MicroRNA expression profile in human macrophages in response to Leishmania major infection von Lemaire, Julien, Mkannez, Ghada, Guerfali, Fatma Z, Gustin, Cindy, Attia, Hanène, Sghaier, Rabiaa M, Dellagi, Koussay, Laouini, Dhafer, Renard, Patricia

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Healed Lesions of Human Cutaneous Leishmaniasis Caused By Leishmania major Do Not Shelter Persistent Residual Parasites von Sghaier, Rabiaa M., Benhnini, Fouad, Guerfali, Fatma Z., Attia, Hanène, Bali, Aymen, Zaatour, Amor, Mkannez, Ghada, Gharbi, Adel, Belhaj-Hamida, Nabil, Dridi, Hichem, Ben-Salah, Afif, Dellagi, Koussay, Laouini, Dhafer

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Enhancer-associated aortic valve stenosis risk locus 1p21.2 alters NFATC2 binding site and promotes fibrogenesis von Chignon, Arnaud, Rosa, Mickael, Boulanger, Marie-Chloé, Argaud, Déborah, Devillers, Romain, Bon-Baret, Valentin, Mkannez, Ghada, Li, Zhonglin, Rufiange, Anne, Gaudreault, Nathalie, Gosselin, David, Thériault, Sébastien, Bossé, Yohan, Mathieu, Patrick

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Enhancer-mediated enrichment of interacting JMJD3-DDX21 to ENPP2 locus prevents R-loop formation and promotes transcription von Argaud, Deborah, Boulanger, Marie-Chloé, Chignon, Arnaud, Mkannez, Ghada, Mathieu, Patrick

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Activated platelets promote an osteogenic programme and the progression of calcific aortic valve stenosis von Bouchareb, Rihab, Boulanger, Marie-Chloé, Tastet, Lionel, Mkannez, Ghada, Nsaibia, Mohamed J, Hadji, Fayez, Dahou, Abdellaziz, Messadeq, Younes, Arsenault, Benoit J, Pibarot, Philippe, Bossé, Yohan, Marette, André, Mathieu, Patrick

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OxLDL-derived lysophosphatidic acid promotes the progression of aortic valve stenosis through a LPAR1-RhoA-NF-κB pathway von Nsaibia, Mohamed Jalloul, Boulanger, Marie-Chloé, Bouchareb, Rihab, Mkannez, Ghada, Le Quang, Khai, Hadji, Fayez, Argaud, Deborah, Dahou, Abdellaziz, Bossé, Yohan, Koschinsky, Marlys L, Pibarot, Philippe, Arsenault, Benoit J, Marette, André, Mathieu, Patrick

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Abstract 12681: Implication of Aurora Kinase B in Pulmonary Arterial Hypertension von Sauvaget, Melanie, Lemay, Sarah-eve, Breuils Bonnet, Sandra, Orcholski, Mark, Mkannez, Ghada, Schimauchi, Kana, Paulin, Roxane, Potus, François, BOUCHERAT, Olivier, Bonnet, Sebastien

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DNA methylation of a PLPP3 MIR transposon-based enhancer promotes an osteogenic programme in calcific aortic valve disease von Mkannez, Ghada, Gagné-Ouellet, Valérie, Jalloul Nsaibia, Mohamed, Boulanger, Marie-Chloé, Rosa, Mickael, Argaud, Deborah, Hadji, Fayez, Gaudreault, Nathalie, Rhéaume, Gabrielle, Bouchard, Luigi, Bossé, Yohan, Mathieu, Patrick

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Implication of EZH2 in the Pro-Proliferative and Apoptosis-Resistant Phenotype of Pulmonary Artery Smooth Muscle Cells in PAH: A Transcriptomic and Proteomic Approach von Habbout, Karima, Omura, Junichi, Awada, Charifa, Bourgeois, Alice, Grobs, Yann, Krishna, Vinod, Breuils-Bonnet, Sandra, Tremblay, Eve, Mkannez, Ghada, Martineau, Sandra, Nadeau, Valérie, Roux-Dalvai, Florence, Orcholski, Mark, Jeyaseelan, Jey, Gutstein, David, Potus, François, Provencher, Steeve, Bonnet, Sébastien, Paulin, Roxane, Boucherat, Olivier

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Abstract 13451: Oxldl-derived Lysophosphatidic Acid Generates a Nf-κB Signature Through Lpar1 That Promotes the Progression of Aortic Valve Stenosis von Nsaibia, Mohamed J, Boulanger, Marie C, Mkannez, Ghada, Bouchareb, Rihab, Bossé, Yohan, Pibarot, Philippe, Arsenault, Benoît, Marette, André, Mathieu, Patrick

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Transcriptomic signature of Leishmania infected mice macrophages: a metabolic point of view von Rabhi, Imen, Rabhi, Sameh, Ben-Othman, Rym, Rasche, Axel, Daskalaki, Adriani, Trentin, Bernadette, Piquemal, David, Regnault, Béatrice, Descoteaux, Albert, Guizani-Tabbane, Lamia

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Letter to the Editor: Hypoxia inducible factor 1α: A critical factor for the immune response to pathogens and Leishmania von Guerfali, Fatma Z., Lemaire, Julien, Mkannez, Ghada, Renard, Patricia, Laouini, Dhafer

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Soluble CD14 is associated with the structural failure of bioprostheses von Nsaibia, Mohamed J., Boulanger, Marie-Chloé, Bouchareb, Rihab, Mkannez, Ghada, Dahou, Abdellaziz, Salaun, Erwan, Bossé, Yohan, Clavel, Marie-Annick, Arsenault, Benoit J., Pibarot, Philippe, Mathieu, Patrick

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Comparative genomics of Tunisian Leishmania major isolates causing human cutaneous leishmaniasis with contrasting clinical severity von Ghouila, Amel, Guerfali, Fatma Z, Atri, Chiraz, Bali, Aymen, Attia, Hanene, Sghaier, Rabiaa M., Mkannez, Ghada, Dickens, Nicholas J., Laouini, Dhafer

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Genetic micro-heterogeneity of Leishmania major in emerging foci of zoonotic cutaneous leishmaniasis in Tunisia von Attia, Hanene, Sghaier, Rabiaa M., Gelanew, Tesfaye, Bali, Aymen, Schweynoch, Carola, Guerfali, Fatma Z., Mkannez, Ghada, Chlif, Sadok, Belhaj-Hamida, Nabil, Dellagi, Koussay, Schönian, Gabriele, Laouini, Dhafer

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Treatment with synthetic lipophilic tyrosyl ester controls Leishmania major infection by reducing parasite load in BALB/c mice von SGHAIER, RABIAA M., AISSA, IMEN, ATTIA, HANÈNE, BALI, AYMEN, LEON MARTINEZ, PABLO A., MKANNEZ, GHADA, GUERFALI, FATMA Z., GARGOURI, YOUSSEF, LAOUINI, DHAFER

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Comparative analysis of resistant and susceptible macrophage gene expression response to Leishmania major parasite von Rabhi, Imen, Rabhi, Sameh, Ben-Othman, Rym, Aniba, Mohamed Radhouane, Trentin, Bernadette, Piquemal, David, Regnault, Béatrice, Guizani-Tabbane, Lamia

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MicroRNA Expression Profile in Human Macrophages in Response to Leishmania major Infection: e2478 von Lemaire, Julien, Mkannez, Ghada, Guerfali, Fatma Z, Gustin, Cindy, Attia, Hanène, Sghaier, Rabiaa M, Dellagi, Koussay, Laouini, Dhafer, Renard, Patricia

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