Identification of Cell-Active Lysine Specific Demethylase 1-Selective Inhibitors von Ueda, Rie, Suzuki, Takayoshi, Mino, Koshiki, Tsumoto, Hiroki, Nakagawa, Hidehiko, Hasegawa, Makoto, Sasaki, Ryuzo, Mizukami, Tamio, Miyata, Naoki

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Rapid Discovery of Highly Potent and Selective Inhibitors of Histone Deacetylase 8 Using Click Chemistry to Generate Candidate Libraries von Suzuki, Takayoshi, Ota, Yosuke, Ri, Masaki, Bando, Masashige, Gotoh, Aogu, Itoh, Yukihiro, Tsumoto, Hiroki, Tatum, Prima R, Mizukami, Tamio, Nakagawa, Hidehiko, Iida, Shinsuke, Ueda, Ryuzo, Shirahige, Katsuhiko, Miyata, Naoki

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Acceleration of Protein Degradation by 20S Proteasome-Binding Peptides Generated by In Vitro Artificial Evolution von Zhu, Yunhao, Shigeyoshi, Kaishin, Hayakawa, Yumiko, Fujiwara, Sae, Kishida, Masamichi, Ohki, Hitoshi, Horibe, Tomohisa, Shionyu, Masafumi, Mizukami, Tamio, Hasegawa, Makoto

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Lysine-Specific Demethylase 1-Selective Inactivators: Protein-Targeted Drug Delivery Mechanism von Ogasawara, Daisuke, Itoh, Yukihiro, Tsumoto, Hiroki, Kakizawa, Taeko, Mino, Koshiki, Fukuhara, Kiyoshi, Nakagawa, Hidehiko, Hasegawa, Makoto, Sasaki, Ryuzo, Mizukami, Tamio, Miyata, Naoki, Suzuki, Takayoshi

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Identification of ryuvidine as a KDM5A inhibitor von Mitsui, Eishin, Yoshida, Shogo, Shinoda, Yui, Matsumori, Yasumasa, Tsujii, Hiroshi, Tsuchida, Mie, Wada, Shuichi, Hasegawa, Makoto, Ito, Akihiro, Mino, Koshiki, Onuki, Tetsuo, Yoshida, Minoru, Sasaki, Ryuzo, Mizukami, Tamio

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Design, Synthesis, Enzyme-Inhibitory Activity, and Effect on Human Cancer Cells of a Novel Series of Jumonji Domain-Containing Protein 2 Histone Demethylase Inhibitors von Hamada, Shohei, Suzuki, Takayoshi, Mino, Koshiki, Koseki, Koichi, Oehme, Felix, Flamme, Ingo, Ozasa, Hiroki, Itoh, Yukihiro, Ogasawara, Daisuke, Komaarashi, Haruka, Kato, Aiko, Tsumoto, Hiroki, Nakagawa, Hidehiko, Hasegawa, Makoto, Sasaki, Ryuzo, Mizukami, Tamio, Miyata, Naoki

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Identification of the KDM2/7 Histone Lysine Demethylase Subfamily Inhibitor and its Antiproliferative Activity von Suzuki, Takayoshi, Ozasa, Hiroki, Itoh, Yukihiro, Zhan, Peng, Sawada, Hideyuki, Mino, Koshiki, Walport, Louise, Ohkubo, Rei, Kawamura, Akane, Yonezawa, Masato, Tsukada, Yuichi, Tumber, Anthony, Nakagawa, Hidehiko, Hasegawa, Makoto, Sasaki, Ryuzo, Mizukami, Tamio, Schofield, Christopher J, Miyata, Naoki

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Identification of SAP155 as the Target of GEX1A (Herboxidiene), an Antitumor Natural Product von Hasegawa, Makoto, Miura, Tatsuhiro, Kuzuya, Kouji, Inoue, Ayu, Won Ki, Se, Horinouchi, Sueharu, Yoshida, Tetsuo, Kunoh, Tatsuki, Koseki, Koichi, Mino, Koshiki, Sasaki, Ryuzo, Yoshida, Minoru, Mizukami, Tamio

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The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1 von Tee, Andrew E, Ling, Dora, Nelson, Charlotte, Atmadibrata, Bernard, Dinger, Marcel E, Xu, Ning, Mizukami, Tamio, Liu, Pei Y, Liu, Bing, Cheung, Belamy, Pasquier, Eddy, Haber, Michelle, Norris, Murray D, Suzuki, Takayoshi, Marshall, Glenn M, Liu, Tao

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Structure and Function of Potential Glycosylation Sites of Dynactin-Associated Protein dynAP von Yin, Xiaobo, Konishi, Takayuki, Horikawa, Kazuo, Tanaka, Ryota, Togo, Yuki, Noda, Takanori, Hosoi, Miho, Tsuchida, Mie, Kunoh, Tatsuki, Wada, Shuichi, Nakamura, Toshinobu, Tsuda, Eisuke, Sasaki, Ryuzo, Mizukami, Tamio, Hasegawa, Makoto

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Identification of SNAIL1 Peptide-Based Irreversible Lysine-Specific Demethylase 1‑Selective Inactivators von Itoh, Yukihiro, Aihara, Keisuke, Mellini, Paolo, Tojo, Toshifumi, Ota, Yosuke, Tsumoto, Hiroki, Solomon, Viswas Raja, Zhan, Peng, Suzuki, Miki, Ogasawara, Daisuke, Shigenaga, Akira, Inokuma, Tsubasa, Nakagawa, Hidehiko, Miyata, Naoki, Mizukami, Tamio, Otaka, Akira, Suzuki, Takayoshi

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Evaluation of phenylcyclopropylamine compounds by enzymatic assay of lysine-specific demethylase 2 in the presence of NPAC peptide von Kakizawa, Taeko, Mizukami, Tamio, Itoh, Yukihiro, Hasegawa, Makoto, Sasaki, Ryuzo, Suzuki, Takayoshi

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Synthesis and biological activity of optically active NCL-1, a lysine-specific demethylase 1 selective inhibitor von Ogasawara, Daisuke, Suzuki, Takayoshi, Mino, Koshiki, Ueda, Rie, Khan, Mohammed Naseer Ahmed, Matsubara, Takuya, Koseki, Koichi, Hasegawa, Makoto, Sasaki, Ryuzo, Nakagawa, Hidehiko, Mizukami, Tamio, Miyata, Naoki

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Regulation of tissue factor pathway inhibitor-2 (TFPI-2) expression by lysine-specific demethylase 1 and 2 (LSD1 and LSD2) von Mino, Koshiki, Nishimura, Satoshi, Ninomiya, Shogo, Tujii, Hiroshi, Matsumori, Yasumasa, Tsuchida, Mie, Hosoi, Miho, Koseki, Koichi, Wada, Shuichi, Hasegawa, Makoto, Sasaki, Ryuzo, Murakami-Yamaguchi, Yukie, Narita, Hiroshi, Suzuki, Takayoshi, Miyata, Naoki, Mizukami, Tamio

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Expression and cell transformation activity of dynactin‐associated protein isoforms von Yin, Xiaobo, Yamada, Shota, Kobayashi, Hiroaki, Tanaka, Ryota, Togo, Yuki, Hosoi, Miho, Tsuchida, Mie, Kunoh, Tatsuki, Wada, Shuichi, Nakamura, Toshinobu, Sasaki, Ryuzo, Mizukami, Tamio, Hasegawa, Makoto

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Human Dynactin-Associated Protein Transforms NIH3T3 Cells to Generate Highly Vascularized Tumors with Weak Cell-Cell Interaction von Kunoh, Tatsuki, Wang, Weixiang, Kobayashi, Hiroaki, Matsuzaki, Daisuke, Togo, Yuki, Tokuyama, Masahiro, Hosoi, Miho, Koseki, Koichi, Wada, Shu-Ichi, Nagai, Nobuo, Nakamura, Toshinobu, Nomura, Shintaro, Hasegawa, Makoto, Sasaki, Ryuzo, Mizukami, Tamio

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A highly oxygenated ergostane—MBJ-0005—from Anthostomella eucalyptorum f25427 von Izumikawa, Miho, Itoh, Masashi, Kawahara, Teppei, Sakata, Noriaki, Tsuchida, Toshio, Mizukami, Tamio, Shin-ya, Kazuo

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Identification of a novel inhibitor of triple-negative breast cancer cell growth by screening of a small-molecule library von Fujita, Tomoyuki, Mizukami, Tamio, Okawara, Tadashi, Inoue, Kengo, Fujimori, Minoru

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Synthesis, LSD1 Inhibitory Activity, and LSD1 Binding Model of Optically Pure Lysine-PCPA Conjugates von Itoh, Yukihiro, Ogasawara, Daisuke, Ota, Yosuke, Mizukami, Tamio, Suzuki, Takayoshi

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A new structural class of proteasome inhibitors identified by microbial screening using yeast-based assay von Asai, Akira, Tsujita, Tetsuya, Sharma, Sreenath V., Yamashita, Yoshinori, Akinaga, Shiro, Funakoshi, Minoru, Kobayashi, Hideki, Mizukami, Tamio

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