The In Vivo Pig-a Gene Mutation Assay von Miura, Daishiro

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The in vivo pig-a gene mutation assay, a potential tool for regulatory safety assessment von Dobrovolsky, Vasily N., Miura, Daishiro, Heflich, Robert H., Dertinger, Stephen D.

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The PIGRET assay, a method for measuring Pig-a gene mutation in reticulocytes, is reliable as a short-term in vivo genotoxicity test: Summary of the MMS/JEMS-collaborative study ac... von Kimoto, Takafumi, Horibata, Katsuyoshi, Miura, Daishiro, Chikura, Satsuki, Okada, Yuki, Ukai, Akiko, Itoh, Satoru, Nakayama, Shiho, Sanada, Hisakazu, Koyama, Naomi, Muto, Shigeharu, Uno, Yoshifumi, Yamamoto, Mika, Suzuki, Yuta, Fukuda, Takayuki, Goto, Ken, Wada, Kunio, Kyoya, Takahiro, Shigano, Miyuki, Takasawa, Hironao, Hamada, Shuichi, Adachi, Hideki, Uematsu, Yasuaki, Tsutsumi, Eri, Hori, Hisako, Kikuzuki, Ryuta, Ogiwara, Yosuke, Yoshida, Ikuma, Maeda, Akihisa, Narumi, Kazunori, Fujiishi, Yohei, Morita, Takeshi, Yamada, Masami, Honma, Masamitsu

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Persistence of vertebral growth plate cartilage in aged cynomolgus monkeys von Iwata, Munetaka, Yamamoto, Wataru, Shimomoto, Takasumi, Okada, Yuki, Oosawa, Satomi, Miura, Daishiro, Hara, Yasushi

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The Rat Pig-a Mutation Assay in Single and 28 Day-repeated Dose Study of Cyclophosphamide: The PIGRET Assay Can Detect the In Vivo Mutagenicity Earlier than the RBC Pig-a Assay von Kimoto, Takafumi, Chikura, Satsuki, Suzuki-Okada, Kumiko, Kobayashi, Xiaomei, Itano, Yasuhiro, Miura, Daishiro, Kasahara, Yoshinori

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Further development of the rat Pig-a mutation assay: Measuring rat Pig-a mutant bone marrow erythroids and a high throughput assay for mutant peripheral blood reticulocytes von Kimoto, Takafumi, Chikura, Satsuki, Suzuki, Kumiko, Kobayashi, Xiao mei, Itano, Yasuhiro, Horibata, Katsuyoshi, Honma, Masamitsu, Dobrovolsky, Vasily N., Heflich, Robert H., Miura, Daishiro, Kasahara, Yoshinori

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Prophylactic treatment with sulphonated immunoglobulin G attenuates development of mechanical allodynia-like response in mice with neuropathic pain von YAMAMOTO, Wataru, ITANO, Yasuhiro, KOBAYASHI, Tsunefumi, MIURA, Daishiro, KASAHARA, Yoshinori

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The in vivo Pig-a gene mutation assay is useful for evaluating the genotoxicity of ionizing radiation in mice von Ohtani, Shin, Unno, Aiko, Ushiyama, Akira, Kimoto, Takafumi, Miura, Daishiro, Kunugita, Naoki

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A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in cynomolgus monkeys von Matsumoto, Emi, Namekawa, Junichi, Kaneko, Hideshi, Shimomoto, Takasumi, Masuyama, Mitsuaki, Fujiwara, Toshihisa, Miura, Daishiro

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A 6-week repeated intranasal dose toxicity study of TTA-121, a novel oxytocin nasal spray, in rats von Namekawa, Junichi, Matsumoto, Emi, Kaneko, Hideshi, Shimomoto, Takasumi, Okamura, Takayuki, Oshikata, Takafumi, Renne, Roger A., Miura, Daishiro

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The effects of long-lasting hypoglycemia on male reproductive organs in rats von Kobayashi, Taiki, Namekawa, Junichi, Shimomoto, Takasumi, Yasui, Mari, Iijima, Takeshi, Itano, Yasuhiro, Miura, Daishiro, Kasahara, Yoshinori

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Detection of In Vivo Mutation in the Pig-a Gene of Mouse Bone Marrow Erythroids von Kimoto, Takafumi, Miura, Daishiro

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Effective use of the Pig-a gene mutation assay for mutagenicity screening: measuring CD59-deficient red blood cells in rats treated with genotoxic chemicals von Kimoto, Takafumi, Chikura, Satsuki, Suzuki-Okada, Kumiko, Kobayashi, Xiao-mei, Itano, Yasuhiro, Miura, Daishiro, Kasahara, Yoshinori

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Flow cytometric detection of Pig-A mutant red blood cells using an erythroid-specific antibody: Application of the method for evaluating the in vivo genotoxicity of methylphenidate... von Dobrovolsky, Vasily N., Boctor, Sherin Y., Twaddle, Nathan C., Doerge, Daniel R., Bishop, Michelle E., Manjanatha, Mugimane G., Kimoto, Takafumi, Miura, Daishiro, Heflich, Robert H., Ferguson, Sherry A.

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A double-blind, placebo-controlled, randomized multiple dose phase 1b trial of a CDK4/6 inhibitor, TCK-276, in patients with active rheumatoid arthritis von Tasaki, Daisuke, Tsuruda, Kazuoki, Sun, Shosho, Tsumura, Yoshinori, Asano, Satoshi, Suzuki, Yuki, Tsujimoto, Shunsuke, Miura, Daishiro, Sato, Hiroaki

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Evaluation of Macaca mulatta as a model for genotoxicity studies von Dobrovolsky, Vasily N., Shaddock, Joseph G., Mittelstaedt, Roberta A., Manjanatha, Mugimane G., Miura, Daishiro, Uchikawa, Makoto, Mattison, Donald R., Morris, Suzanne M.

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Fullerene (C60) Is Negative in the In Vivo Pig-A Gene Mutation Assay von Horibata, Katsuyoshi, Ukai, Akiko, Koyama, Naoki, Takagi, Atsuya, Kanno, Jun, Kimoto, Takafumi, Miura, Daishiro, Hirose, Akihiko, Honma, Masamitsu

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DNA MICROARRAY ANALYSIS OF PULMONARY FIBROSIS THREE MONTHS AFTER EXPOSURE TO PARAQUAT IN RATS von SATOMI, Yoshihide, TSUCHIYA, Wakana, MIURA, Daishiro, KASAHARA, Yoshinori, AKAHORI, Fumiaki

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The rat Pig-a assay using an erythroid HIS49 antibody in a single dose study of isopropyl p-toluenesulfonate von Chikura, Satsuki, Okada, Yuki, Kimoto, Takafumi, Kaneko, Hideshi, Miura, Daishiro, Kasahara, Yoshinori

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Development of an in vivo gene mutation assay using the endogenous Pig-A gene: I. Flow cytometric detection of CD59-negative peripheral red blood cells and CD48-negative spleen T-c... von Miura, Daishiro, Dobrovolsky, Vasily N., Kasahara, Yoshinori, Katsuura, Yasuhiro, Heflich, Robert H.

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