Identification of hepatokines involved in pathology of type 2 diabetes and obesity von Misu, Hirofumi

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Pathophysiological significance of hepatokine overproduction in type 2 diabetes von Misu, Hirofumi

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Comparison of Human Selenoprotein P Determinants in Serum between Our Original Methods and Commercially Available Kits von Saito, Yoshiro, Misu, Hirofumi, Takayama, Hiroaki, Takashima, Shin-ichiro, Usui, Soichiro, Takamura, Masayuki, Kaneko, Shuichi, Takamura, Toshinari, Noguchi, Noriko

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Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models von Mita, Yuichiro, Nakayama, Kaho, Inari, Shogo, Nishito, Yukina, Yoshioka, Yuya, Sakai, Naoko, Sotani, Kanade, Nagamura, Takahiro, Kuzuhara, Yuki, Inagaki, Kumi, Iwasaki, Miki, Misu, Hirofumi, Ikegawa, Masaya, Takamura, Toshinari, Noguchi, Noriko, Saito, Yoshiro

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Deficiency of the hepatokine selenoprotein P increases responsiveness to exercise in mice through upregulation of reactive oxygen species and AMP-activated protein kinase in muscle von Misu, Hirofumi, Takayama, Hiroaki, Saito, Yoshiro, Mita, Yuichiro, Kikuchi, Akihiro, Ishii, Kiyo-aki, Chikamoto, Keita, Kanamori, Takehiro, Tajima, Natsumi, Lan, Fei, Takeshita, Yumie, Honda, Masao, Tanaka, Mutsumi, Kato, Seiji, Matsuyama, Naoto, Yoshioka, Yuya, Iwayama, Kaito, Tokuyama, Kumpei, Akazawa, Nobuhiko, Maeda, Seiji, Takekoshi, Kazuhiro, Matsugo, Seiichi, Noguchi, Noriko, Kaneko, Shuichi, Takamura, Toshinari

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Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria von Nakamura, Seiji, Takamura, Toshinari, Matsuzawa-Nagata, Naoto, Takayama, Hiroaki, Misu, Hirofumi, Noda, Hiroyo, Nabemoto, Satoko, Kurita, Seiichiro, Ota, Tsuguhito, Ando, Hitoshi, Miyamoto, Ken-ichi, Kaneko, Shuichi

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Fatty liver as a consequence and cause of insulin resistance: Lessons from type 2 diabetic liver von Takamura, Toshinari, Misu, Hirofumi, Ota, Tsuguhito, Kaneko, Shuichi

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Concentration-dependent dual effects of hydrogen peroxide on insulin signal transduction in H4IIEC hepatocytes von Iwakami, Satoshi, Misu, Hirofumi, Takeda, Takashi, Sugimori, Makoto, Matsugo, Seiichi, Kaneko, Shuichi, Takamura, Toshinari

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Increased oxidative stress precedes the onset of high-fat diet–induced insulin resistance and obesity von Matsuzawa-Nagata, Naoto, Takamura, Toshinari, Ando, Hitoshi, Nakamura, Seiji, Kurita, Seiichiro, Misu, Hirofumi, Ota, Tsuguhito, Yokoyama, Masayoshi, Honda, Masao, Miyamoto, Ken-ichi, Kaneko, Shuichi

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Inverse correlation between serum levels of selenoprotein P and adiponectin in patients with type 2 diabetes von Misu, Hirofumi, Ishikura, Kazuhide, Kurita, Seiichiro, Takeshita, Yumie, Ota, Tsuguhito, Saito, Yoshiro, Takahashi, Kazuhiko, Kaneko, Shuichi, Takamura, Toshinari

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Circulating Concentrations of Insulin Resistance-Associated Hepatokines, Selenoprotein P and Leukocyte Cell-Derived Chemotaxin 2, during an Oral Glucose Tolerance Test in Humans von Mohri, Kensuke, Misu, Hirofumi, Takayama, Hiroaki, Ishii, Kiyo-aki, Kikuchi, Akihiro, Lan, Fei, Enyama, Yasufumi, Takeshita, Yumie, Saito, Yoshiro, Kaneko, Shuichi, Takamura, Toshinari

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Inhibin βE (INHBE) is a possible insulin resistance-associated hepatokine identified by comprehensive gene expression analysis in human liver biopsy samples von Sugiyama, Masakazu, Kikuchi, Akihiro, Misu, Hirofumi, Igawa, Hirobumi, Ashihara, Motooki, Kushima, Youichi, Honda, Kiyofumi, Suzuki, Yoshiyuki, Kawabe, Yoshiki, Kaneko, Shuichi, Takamura, Toshinari

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Serum selenoprotein P, but not selenium, predicts future hyperglycemia in a general Japanese population von Oo, Swe Mar, Misu, Hirofumi, Saito, Yoshiro, Tanaka, Mutsumi, Kato, Seiji, Kita, Yuki, Takayama, Hiroaki, Takeshita, Yumie, Kanamori, Takehiro, Nagano, Toru, Nakagen, Masatoshi, Urabe, Takeshi, Matsuyama, Naoto, Kaneko, Shuichi, Takamura, Toshinari

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Plasma half-life and tissue distribution of leukocyte cell-derived chemotaxin 2 in mice von Kikuchi, Akihiro, Takayama, Hiroaki, Tsugane, Hirohiko, Shiba, Kazuhiro, Chikamoto, Keita, Yamamoto, Tatsuya, Matsugo, Seiichi, Ishii, Kiyo-aki, Misu, Hirofumi, Takamura, Toshinari

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Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepa... von Tajima-Shirasaki, Natsumi, Ishii, Kiyo-aki, Takayama, Hiroaki, Shirasaki, Takayoshi, Iwama, Hisakazu, Chikamoto, Keita, Saito, Yoshiro, Iwasaki, Yasumasa, Teraguchi, Atsushi, Lan, Fei, Kikuchi, Akihiro, Takeshita, Yumie, Murao, Koji, Matsugo, Seiichi, Kaneko, Shuichi, Misu, Hirofumi, Takamura, Toshinari

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Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver von OTODA, Toshiki, TAKAMURA, Toshinari, FEI LAN, TAKEDA, Takashi, KURITA, Seiichiro, ISHIKURA, Kazuhide, KITA, Yuki, IWAYAMA, Kaito, KATO, Ken-Ichiro, UNO, Masafumi, TAKESHITA, Yumie, YAMAMOTO, Miyuki, MISU, Hirofumi, TOKUYAMA, Kunpei, ISEKI, Shoichi, TANAKA, Keiji, KANEKO, Shuichi, OTA, Tsuguhito, MURATA, Shigeo, HAYASHI, Hiroto, TAKAYAMA, Hiroaki, KIKUCHI, Akihiro, KANAMORI, Takehiro, SHIMA, Kosuke R

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Metformin Suppresses Expression of the Selenoprotein P Gene via an AMP-activated Kinase (AMPK)/FoxO3a Pathway in H4IIEC3 Hepatocytes von Takayama, Hiroaki, Misu, Hirofumi, Iwama, Hisakazu, Chikamoto, Keita, Saito, Yoshiro, Murao, Koji, Teraguchi, Atsushi, Lan, Fei, Kikuchi, Akihiro, Saito, Reina, Tajima, Natsumi, Shirasaki, Takayoshi, Matsugo, Seiichi, Miyamoto, Ken-ichi, Kaneko, Shuichi, Takamura, Toshinari

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Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity von Murai, Kazuhisa, Honda, Masao, Shirasaki, Takayoshi, Shimakami, Tetsuro, Omura, Hitoshi, Misu, Hirofumi, Kita, Yuki, Takeshita, Yumie, Ishii, Kiyo-aki, Takamura, Toshinari, Urabe, Takeshi, Shimizu, Ryogo, Okada, Hikari, Yamashita, Taro, Sakai, Yoshio, Kaneko, Shuichi

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Ectopic fat accumulation and distant organ-specific insulin resistance in Japanese people with nonalcoholic fatty liver disease von Kato, Ken-ichiro, Takamura, Toshinari, Takeshita, Yumie, Ryu, Yasuji, Misu, Hirofumi, Ota, Tsuguhito, Tokuyama, Kumpei, Nagasaka, Shoichiro, Matsuhisa, Munehide, Matsui, Osamu, Kaneko, Shuichi

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Effects of metformin and alogliptin on body composition in people with type 2 diabetes von Takeshita, Yumie, Kita, Yuki, Kato, Ken‐ichiro, Kanamori, Takehiro, Misu, Hirofumi, Kaneko, Shuichi, Takamura, Toshinari

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