ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157 von Feuerbach, Dominik, Schindler, Patrick, Barske, Carmen, Joller, Stefanie, Beng-Louka, Edwige, Worringer, Katie A., Kommineni, Sravya, Kaykas, Ajamete, Ho, Daniel J., Ye, Chaoyang, Welzenbach, Karl, Elain, Gaelle, Klein, Laurent, Brzak, Irena, Mir, Anis K., Farady, Christopher J., Aichholz, Reiner, Popp, Simone, George, Nathalie, Neumann, Ulf

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The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes von Elain, Gaelle, Jeanneau, Karine, Rutkowska, Aleksandra, Mir, Anis K., Dev, Kumlesh K.

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Fractalkine shedding is mediated by p38 and the ADAM10 protease under pro-inflammatory conditions in human astrocytes von O'Sullivan, Sinead A, Gasparini, Fabrizio, Mir, Anis K, Dev, Kumlesh K

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Fingolimod attenuates splenocyte-induced demyelination in cerebellar slice cultures von Pritchard, Adam J, Mir, Anis K, Dev, Kumlesh K

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The dual S1PR1/S1PR5 drug BAF312 (Siponimod) attenuates demyelination in organotypic slice cultures von O'Sullivan, Catherine, Schubart, Anna, Mir, Anis K, Dev, Kumlesh K

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Monocyte Chemoattractant Protein-1 Deficiency Is Protective in a Murine Stroke Model von Hughes, Paula M., Allegrini, Peter R., Rudin, Markus, Perry, V. Hugh, Mir, Anis K., Wiessner, Christoph

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Recovery and brain reorganization after stroke in adult and aged rats von Markus, Tiffanie M., Tsai, Shih-Yen, Bollnow, Melanie R., Farrer, Robert G., O'Brien, Timothy E., Kindler-Baumann, Diana R., Rausch, Martin, Rudin, Markus, Wiessner, Christoph, Mir, Anis K., Schwab, Martin E., Kartje, Gwendolyn L.

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Neutralization of interleukin-1β reduces cerebral edema and tissue loss and improves late cognitive outcome following traumatic brain injury in mice von Clausen, Fredrik, Hånell, Anders, Israelsson, Charlotte, Hedin, Johanna, Ebendal, Ted, Mir, Anis K., Gram, Hermann, Marklund, Niklas

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Neutralization of interleukin-1β modifies the inflammatory response and improves histological and cognitive outcome following traumatic brain injury in mice von Clausen, Fredrik, Hånell, Anders, Björk, Maria, Hillered, Lars, Mir, Anis K., Gram, Hermann, Marklund, Niklas

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Delayed anti-nogo-a antibody application after spinal cord injury shows progressive loss of responsiveness von Gonzenbach, Roman R, Zoerner, Bjoern, Schnell, Lisa, Weinmann, Oliver, Mir, Anis K, Schwab, Martin E

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Diffuse traumatic axonal injury in mice induces complex behavioural alterations that are normalized by neutralization of interleukin-1β von Ekmark-Lewén, Sara, Flygt, Johanna, Fridgeirsdottir, Gudrun A., Kiwanuka, Olivia, Hånell, Anders, Meyerson, Bengt J., Mir, Anis K., Gram, Hermann, Lewén, Anders, Clausen, Fredrik, Hillered, Lars, Marklund, Niklas

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Anti-Nogo-A Antibody Infusion 24 Hours After Experimental Stroke Improved Behavioral Outcome and Corticospinal Plasticity in Normotensive and Spontaneously Hypertensive Rats von Wiessner, Christoph, Bareyre, Florence M., Allegrini, Peter R., Mir, Anis K., Frentzel, Stefan, Zurini, Mauro, Schnell, Lisa, Oertle, Thomas, Schwab, Martin E.

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Intrathecal treatment with anti-Nogo-A antibody improves functional recovery in adult rats after stroke von TSAI, Shih-Yen, MARKUS, Tiffanie M, ANDREWS, Ellen M, CHEATWOOD, Joseph L, EMERICK, April J, MIR, Anis K, SCHWAB, Martin E, KARTJE, Gwendolyn L

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Targeting monocyte chemoattractant protein-1 signalling in disease von Dawson, Janet, Miltz, Wolfgang, Mir, Anis K, Wiessner, Christoph

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Cognitive outcome following brain injury and treatment with an inhibitor of Nogo-A in association with an attenuated downregulation of hippocampal growth-associated protein-43 expr... von MARKLUND, Niklas, BAREYRE, Florence M, ROYO, Nicolas C, THOMPSON, Hilaire J, MIR, Anis K, GRADY, M. Sean, SCHWAB, Martin E, MCINTOSH, Tracy K

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Nogo-A inhibition induces recovery from neglect in rats von Brenneman, Miranda M., Wagner, Steven J., Cheatwood, Joseph L., Heldt, Scott A., Corwin, James V., Reep, Roger L., Kartje, Gwendolyn L., Mir, Anis K., Schwab, Martin E.

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Anti-Nogo-A antibody infusion 24 hours after experimental stroke improved behavioral outcome and corticospinal plasticity in normotensive and spontaneously hypertensive rats von WIESSNER, Christoph, BAREYRE, Florence M, ALLEGRINI, Peter R, MIR, Anis K, FRENTZEL, Stefan, ZURINI, Mauro, SCHNELL, Lisa, OERTLE, Thomas, SCHWAB, Tmartin E

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Zinc metalloproteinase-mediated cleavage of the human Nogo-66 receptor von Walmsley, Adrian R, McCombie, Gregor, Neumann, Ulf, Marcellin, David, Hillenbrand, Rainer, Mir, Anis K, Frentzel, Stefan

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Ectodomain shedding of human Nogo-66 receptor homologue-1 by zinc metalloproteinases von Walmsley, Adrian R., Mir, Anis K., Frentzel, Stefan

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The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes: IL17 Regulates IL16 Levels in Astrocytes von Elain, Gaelle, Jeanneau, Karine, Rutkowska, Aleksandra, Mir, Anis K., Dev, Kumlesh K.

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