Exosomal delivery of doxorubicin enables rapid cell entry and enhanced in vitro potency von Schindler, Christina, Collinson, Andie, Matthews, Carl, Pointon, Amy, Jenkinson, Lesley, Minter, Ralph R, Vaughan, Tristan J, Tigue, Natalie J

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Engineering therapeutic proteins for cell entry: the natural approach von Guillard, Sandrine, Minter, Ralph R, Jackson, Ronald H

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High affinity single-chain variable fragments are specific and versatile targeting motifs for extracellular vesicles von Longatti, Andrea, Schindler, Christina, Collinson, Andie, Jenkinson, Lesley, Matthews, Carl, Fitzpatrick, Laura, Blundy, Margaret, Minter, Ralph, Vaughan, Tristan, Shaw, Michael, Tigue, Natalie

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In vitro evolution of antibody affinity via insertional scanning mutagenesis of an entire antibody variable region von Skamaki, Kalliopi, Emond, Stephane, Chodorge, Matthieu, Andrews, John, Rees, D. Gareth, Cannon, Daniel, Popovic, Bojana, Buchanan, Andrew, Minter, Ralph R., Hollfelder, Florian

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KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe von Bery, Nicolas, Legg, Sandrine, Debreczeni, Judit, Breed, Jason, Embrey, Kevin, Stubbs, Christopher, Kolasinska-Zwierz, Paulina, Barrett, Nathalie, Marwood, Rose, Watson, Jo, Tart, Jon, Overman, Ross, Miller, Ami, Phillips, Christopher, Minter, Ralph, Rabbitts, Terence H.

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Structural and functional characterization of a DARPin which inhibits Ras nucleotide exchange von Guillard, Sandrine, Kolasinska-Zwierz, Paulina, Debreczeni, Judit, Breed, Jason, Zhang, Jing, Bery, Nicolas, Marwood, Rose, Tart, Jon, Overman, Ross, Stocki, Pawel, Mistry, Bina, Phillips, Christopher, Rabbitts, Terence, Jackson, Ronald, Minter, Ralph

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Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures von Galson, Jacob D, Schaetzle, Sebastian, Bashford-Rogers, Rachael J M, Raybould, Matthew I J, Kovaltsuk, Aleksandr, Kilpatrick, Gavin J, Minter, Ralph, Finch, Donna K, Dias, Jorge, James, Louisa K, Thomas, Gavin, Lee, Wing-Yiu Jason, Betley, Jason, Cavlan, Olivia, Leech, Alex, Deane, Charlotte M, Seoane, Joan, Caldas, Carlos, Pennington, Daniel J, Pfeffer, Paul, Osbourn, Jane

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A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies von Macleod, Olivia J. S., Bart, Jean-Mathieu, MacGregor, Paula, Peacock, Lori, Savill, Nicholas J., Hester, Svenja, Ravel, Sophie, Sunter, Jack D., Trevor, Camilla, Rust, Steven, Vaughan, Tristan J., Minter, Ralph, Mohammed, Shabaz, Gibson, Wendy, Taylor, Martin C., Higgins, Matthew K., Carrington, Mark

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Phenotypic screening: the future of antibody discovery von Gonzalez-Munoz, Andrea L., Minter, Ralph R., Rust, Steven J.

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A Shorter Route to Antibody Binders via Quantitative in vitro Bead-Display Screening and Consensus Analysis von Mankowska, Sylwia A., Gatti-Lafranconi, Pietro, Chodorge, Matthieu, Sridharan, Sudharsan, Minter, Ralph R., Hollfelder, Florian

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Phenotypic whole-cell screening identifies a protective carbohydrate epitope on Klebsiella pneumoniae von Berry, Sophia K, Rust, Steven, Caceres, Carolina, Irving, Lorraine, Bartholdson Scott, Josefin, Tabor, David E, Dougan, Gordon, Christie, Graham, Warrener, Paul, Minter, Ralph, Grant, Andrew J

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Targeted protein degradation using chimeric human E2 ubiquitin-conjugating enzymes von Taylor, Jonathan D., Barrett, Nathalie, Martinez Cuesta, Sergio, Cassidy, Katelyn, Pachl, Fiona, Dodgson, James, Patel, Radhika, Eriksson, Tuula M., Riley, Aidan, Burrell, Matthew, Bauer, Christin, Rees, D. Gareth, Cimbro, Raffaello, Zhang, Andrew X., Minter, Ralph R., Hunt, James, Legg, Sandrine

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Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type von Rust, Steven, Guillard, Sandrine, Sachsenmeier, Kris, Hay, Carl, Davidson, Max, Karlsson, Anders, Karlsson, Roger, Brand, Erin, Lowne, David, Elvin, John, Flynn, Matt, Kurosawa, Gene, Hollingsworth, Robert, Jermutus, Lutz, Minter, Ralph

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Characterization of mAbs against Klebsiella pneumoniae type 3 fimbriae isolated in a target-independent phage display campaign von Berry, Sophia K, Rust, Steven, Irving, Lorraine, Bartholdson Scott, Josefin, Weinert, Lucy A, Dougan, Gordon, Christie, Graham, Warrener, Paul, Minter, Ralph, Grant, Andrew J

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Phenotypic screening—the fast track to novel antibody discovery von Minter, Ralph R., Sandercock, Alan M., Rust, Steven J.

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Harnessing phage and ribosome display for antibody optimisation von Dufner, Patrick, Jermutus, Lutz, Minter, Ralph R.

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A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis von MacGregor, Paula, Gonzalez-Munoz, Andrea L, Jobe, Fatoumatta, Taylor, Martin C, Rust, Steven, Sandercock, Alan M, Macleod, Olivia J S, Van Bocxlaer, Katrien, Francisco, Amanda F, D'Hooge, Francois, Tiberghien, Arnaud, Barry, Conor S, Howard, Philip, Higgins, Matthew K, Vaughan, Tristan J, Minter, Ralph, Carrington, Mark

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A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding von Douthwaite, Julie, Moisan, Jacques, Privezentzev, Cyril, Soskic, Blagoje, Sabbah, Shereen, Cohen, Suzanne, Collinson, Andie, England, Elizabeth, Huntington, Catherine, Kemp, Ben, Zhuang, Li, Hudak, Suzanne, Rees, D Gareth, Goldberg, Debbie, Barton, Chris, Chang, Linda, Vainshtein, Inna, Liang, Meina, Iciek, Laurie, Ambery, Philip, Peakman, Mark, Vaughan, Tristan J, Tree, Tim I M, Sansom, David M, Bowen, Michael A, Minter, Ralph R, Jermutus, Lutz

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Engineering a therapeutic IgG molecule to address cysteinylation, aggregation and enhance thermal stability and expression von Buchanan, Andrew, Clementel, Veronica, Woods, Rob, Harn, Nicholas, Bowen, Michael A, Mo, Wenjun, Popovic, Bojana, Bishop, Steven M., Dall'Acqua, William, Minter, Ralph, Jermutus, Lutz, Bedian, Vahe

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Probing a Protein-Protein Interaction by in vitro Evolution von Thom, George, Cockroft, Alexis C., Buchanan, Andrew G., Candotti, Cathy Joberty, Cohen, E. Suzanne, Lowne, David, Monk, Phill, Shorrock-Hart, Celia P., Jermutus, Lutz, Minter, Ralph R.

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