Apolipoprotein M supports S1P production and conservation and mediates prolonged Akt activation via S1PR1 and S1PR3 von Kiyozuka, Keisuke, Zhao, Xian, Konishi, Akimitsu, Minamishima, Yoji Andrew, Obinata, Hideru

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Development of drugs targeting hypoxia‐inducible factor against tumor cells with VHL mutation: Story of 127 years von Takamori, Hajime, Yamasaki, Toshinari, Kitadai, Rui, Minamishima, Yoji Andrew, Nakamura, Eijiro

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Characterization of recombinant murine GDE4 and GDE7, enzymes producing lysophosphatidic acid and/or cyclic phosphatidic acid von Tserendavga, Binderiya, Ohshima, Noriyasu, Fujita, Chiaki, Yuzawa, Koji, Ohshima, Mari, Yanaka, Noriyuki, Minamishima, Yoji Andrew, Izumi, Takashi

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Hypoxic response as a therapeutic target of human diseases von Minamishima, Yoji Andrew

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Inactivation of ackA and pta Genes Reduces GlpT Expression and Susceptibility to Fosfomycin in Escherichia coli von Hirakawa, Hidetada, Takita, Ayako, Sato, Yumika, Hiramoto, Suguru, Hashimoto, Yusuke, Ohshima, Noriyasu, Minamishima, Yoji A, Murakami, Masami, Tomita, Haruyoshi

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VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400 von Young, Arthur P, Li, Lianjie, Grisanzio, Chiara, Zhang, Qing, Schlisio, Susanne, Kaelin, William G, Minamishima, Yoji Andrew, Signoretti, Sabina

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Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss von Minamishima, Yoji Andrew, Kaelin, William G. Jr

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Hydrogen Sulfide Improves Survival After Cardiac Arrest and Cardiopulmonary Resuscitation via a Nitric Oxide Synthase 3-Dependent Mechanism in Mice von MINAMISHIMA, Shizuka, BOUGAKI, Masahiko, SIPS, Patrick Y, JIA DE YU, MINAMISHIMA, Yoji Andrew, ELROD, John W, LEFER, David J, BLOCH, Kenneth D, ICHINOSE, Fumito

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Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure von Minamishima, Yoji Andrew, Moslehi, Javid, Bardeesy, Nabeel, Cullen, Darragh, Bronson, Roderick T., Kaelin, William G.

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Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy von MOSLEHI, Javid, MINAMISHIMA, Yoji Andrew, JIANRU SHI, NEUBERG, Donna, CHARYTAN, David M, PADERA, Robert F, SIGNORETTI, Sabina, LIAO, Ronglih, KAELIN, William G

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Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle von Suhara, Tomohiro, Hishiki, Takako, Kasahara, Masataka, Hayakawa, Noriyo, Oyaizu, Tomoko, Nakanishi, Tsuyoshi, Kubo, Akiko, Morisaki, Hiroshi, Kaelin, William G., Suematsu, Makoto, Minamishima, Yoji Andrew

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Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1 von Lin, Wenchu, Cao, Jian, Liu, Jiayun, Beshiri, Michael L, Fujiwara, Yuko, Francis, Joshua, Cherniack, Andrew D, Geisen, Christoph, Blair, Lauren P, Zou, Mike R, Shen, Xiaohua, Kawamori, Dan, Liu, Zongzhi, Grisanzio, Chiara, Watanabe, Hideo, Minamishima, Yoji Andrew, Zhang, Qing, Kulkarni, Rohit N, Signoretti, Sabina, Rodig, Scott J, Bronson, Roderick T, Orkin, Stuart H, Tuck, David P, Benevolenskaya, Elizaveta V, Meyerson, Matthew, Kaelin, William G. Jr, Yan, Qin

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Energy management by enhanced glycolysis in G1-phase in human colon cancer cells in vitro and in vivo von Bao, Yan, Mukai, Kuniaki, Hishiki, Takako, Kubo, Akiko, Ohmura, Mitsuyo, Sugiura, Yuki, Matsuura, Tomomi, Nagahata, Yoshiko, Hayakawa, Noriyo, Yamamoto, Takehiro, Fukuda, Ryo, Saya, Hideyuki, Suematsu, Makoto, Minamishima, Yoji Andrew

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Obesity-induced kidney injury is attenuated by amelioration of aberrant PHD2 activation in proximal tubules von Futatsugi, Koji, Tokuyama, Hirobumi, Shibata, Shinsuke, Naitoh, Makiko, Kanda, Takeshi, Minakuchi, Hitoshi, Yamaguchi, Shintaro, Hayashi, Koichi, Minamishima, Yoji Andrew, Yanagita, Motoko, Wakino, Shu, Itoh, Hiroshi

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Hypoxia-Inducible Factor Linked to Differential Kidney Cancer Risk Seen with Type 2A and Type 2B VHL Mutations von Li, Lianjie, Zhang, Liang, Zhang, Xiaoping, Yan, Qin, Minamishima, Yoji Andrew, Olumi, Aria F., Mao, Mao, Bartz, Steven, Kaelin, William G.

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Prolyl-hydroxylase PHD3 interacts with pyruvate dehydrogenase (PDH)-E1β and regulates the cellular PDH activity von Kikuchi, Daisuke, Minamishima, Yoji Andrew, Nakayama, Koh

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Actin-binding protein filamin B regulates the cell-surface retention of endothelial sphingosine 1-phosphate receptor 1 von Zhao, Xian, Kiyozuka, Keisuke, Konishi, Akimitsu, Kawabata-Iwakawa, Reika, Minamishima, Yoji Andrew, Obinata, Hideru

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A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo von Minamishima, Yoji Andrew, Moslehi, Javid, Padera, Robert F., Bronson, Roderick T., Liao, Ronglih, Kaelin, William G.

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Acquired platinum resistance involves epithelial to mesenchymal transition through ubiquitin ligase FBXO32 dysregulation von Tanaka, Nobuyuki, Kosaka, Takeo, Miyazaki, Yasumasa, Mikami, Shuji, Niwa, Naoya, Otsuka, Yutaro, Minamishima, Yoji Andrew, Mizuno, Ryuichi, Kikuchi, Eiji, Miyajima, Akira, Sabe, Hisataka, Okada, Yasunori, Uhlén, Per, Suematsu, Makoto, Oya, Mototsugu

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Failure to sense energy depletion may be a novel therapeutic target in chronic kidney disease von Kikuchi, Hiroaki, Sasaki, Emi, Nomura, Naohiro, Mori, Takayasu, Minamishima, Yoji Andrew, Yoshizaki, Yuki, Takahashi, Naohiro, Furusho, Taisuke, Arai, Yohei, Mandai, Shintaro, Yamashita, Takahiro, Ando, Fumiaki, Maejima, Yasuhiro, Isobe, Kiyoshi, Okado, Tomokazu, Rai, Tatemitsu, Uchida, Shinichi, Sohara, Eisei

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