Targeting of eIF6-driven translation induces a metabolic rewiring that reduces NAFLD and the consequent evolution to hepatocellular carcinoma von Scagliola, Alessandra, Miluzio, Annarita, Ventura, Gabriele, Oliveto, Stefania, Cordiglieri, Chiara, Manfrini, Nicola, Cirino, Delia, Ricciardi, Sara, Valenti, Luca, Baselli, Guido, D’Ambrosio, Roberta, Maggioni, Marco, Brina, Daniela, Bresciani, Alberto, Biffo, Stefano

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MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state von Poli, Vittoria, Fagnocchi, Luca, Fasciani, Alessandra, Cherubini, Alessandro, Mazzoleni, Stefania, Ferrillo, Sara, Miluzio, Annarita, Gaudioso, Gabriella, Vaira, Valentina, Turdo, Alice, Gaggianesi, Miriam, Chinnici, Aurora, Lipari, Elisa, Bicciato, Silvio, Bosari, Silvano, Todaro, Matilde, Zippo, Alessio

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Inhibition of eIF6 Activity Reduces Hepatocellular Carcinoma Growth: An In Vivo and In Vitro Study von Scagliola, Alessandra, Miluzio, Annarita, Mori, Giada, Ricciardi, Sara, Oliveto, Stefania, Manfrini, Nicola, Biffo, Stefano

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Translating the Game: Ribosomes as Active Players von Calamita, Piera, Gatti, Guido, Miluzio, Annarita, Scagliola, Alessandra, Biffo, Stefano

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mTOR-dependent translation drives tumor infiltrating CD8 + effector and CD4 + Treg cells expansion von De Ponte Conti, Benedetta, Miluzio, Annarita, Grassi, Fabio, Abrignani, Sergio, Biffo, Stefano, Ricciardi, Sara

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Eukaryotic initiation factor 6 mediates a continuum between 60S ribosome biogenesis and translation von Miluzio, Annarita, Beugnet, Anne, Volta, Viviana, Biffo, Stefano

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Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation von Gandin, Valentina, Marchisio, Pier Carlo, Kiyokawa, Hiroaki, Miluzio, Annarita, Barbieri, Anna Maria, Biffo, Stefano, Beugnet, Anne

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eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription von Brina, Daniela, Miluzio, Annarita, Ricciardi, Sara, Clarke, Kim, Davidsen, Peter K., Viero, Gabriella, Tebaldi, Toma, Offenhäuser, Nina, Rozman, Jan, Rathkolb, Birgit, Neschen, Susanne, Klingenspor, Martin, Wolf, Eckhard, Gailus-Durner, Valerie, Fuchs, Helmut, Hrabe de Angelis, Martin, Quattrone, Alessandro, Falciani, Francesco, Biffo, Stefano

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Impairment of Cytoplasmic eIF6 Activity Restricts Lymphomagenesis and Tumor Progression without Affecting Normal Growth von Miluzio, Annarita, Beugnet, Anne, Grosso, Stefano, Brina, Daniela, Mancino, Marilena, Campaner, Stefano, Amati, Bruno, de Marco, Ario, Biffo, Stefano

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Translational control by 80S formation and 60S availability: The central role of eIF6, a rate limiting factor in cell cycle progression and tumorigenesis von Brina, Daniela, Grosso, Stefano, Miluzio, Annarita, Biffo, Stefano

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SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Interventio... von Calamita, Piera, Miluzio, Annarita, Russo, Arianna, Pesce, Elisa, Ricciardi, Sara, Khanim, Farhat, Cheroni, Cristina, Alfieri, Roberta, Mancino, Marilena, Gorrini, Chiara, Rossetti, Grazisa, Peluso, Ivana, Pagani, Massimiliano, Medina, Diego L, Rommens, Johanna, Biffo, Stefano

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Author Correction: MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state von Poli, Vittoria, Fagnocchi, Luca, Fasciani, Alessandra, Cherubini, Alessandro, Mazzoleni, Stefania, Ferrillo, Sara, Miluzio, Annarita, Gaudioso, Gabriella, Vaira, Valentina, Turdo, Alice, Gaggianesi, Miriam, Chinnici, Aurora, Lipari, Elisa, Bicciato, Silvio, Bosari, Silvano, Todaro, Matilde, Zippo, Alessio

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Discovery and Preliminary Characterization of Translational Modulators that Impair the Binding of eIF6 to 60S Ribosomal Subunits von Pesce, Elisa, Miluzio, Annarita, Turcano, Lorenzo, Minici, Claudia, Cirino, Delia, Calamita, Piera, Manfrini, Nicola, Oliveto, Stefania, Ricciardi, Sara, Grifantini, Renata, Degano, Massimo, Bresciani, Alberto, Biffo, Stefano

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Translational Control of Metabolism and Cell Cycle Progression in Hepatocellular Carcinoma von Scagliola, Alessandra, Miluzio, Annarita, Biffo, Stefano

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eIF6 anti-association activity is required for ribosome biogenesis, translational control and tumor progression von Brina, Daniela, Miluzio, Annarita, Ricciardi, Sara, Biffo, Stefano

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Data on the effects of eIF6 downmodulation on the proportions of innate and adaptive immune system cell subpopulations and on thymocyte maturation von Manfrini, Nicola, Ricciardi, Sara, Miluzio, Annarita, Fedeli, Maya, Scagliola, Alessandra, Gallo, Simone, Adler, Thure, Busch, Dirk H., Gailus-Durner, Valerie, Fuchs, Helmut, de Angelis, Martin Hrabě, Biffo, Stefano

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Assessment of Sacsin Turnover in Patients With ARSACS: Implications for Molecular Diagnosis and Pathogenesis von Longo, Fabiana, De Ritis, Daniele, Miluzio, Annarita, Fraticelli, Davide, Baets, Jonathan, Scarlato, Marina, Santorelli, Filippo M., Biffo, Stefano, Maltecca, Francesca

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Differential Cytokine Pattern in the Spleens and Livers of BALB/c Mice Infected with Penicillium marneffei: Protective Role of Gamma Interferon von Sisto, Francesca, Miluzio, Annarita, Leopardi, Orazio, Mirra, Maurizio, Boelaert, Johan R, Taramelli, Donatella

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The Paradox of Ribosomal Insufficiency Coupled with Increased Cancer: Shifting the Perspective from the Cancer Cell to the Microenvironment von D'Andrea, Giacomo, Deroma, Giorgia, Miluzio, Annarita, Biffo, Stefano

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A Polysome-Based microRNA Screen Identifies miR-24-3p as a Novel Promigratory miRNA in Mesothelioma von Oliveto, Stefania, Alfieri, Roberta, Miluzio, Annarita, Scagliola, Alessandra, Secli, Raissa S, Gasparini, Pierluigi, Grosso, Stefano, Cascione, Luciano, Mutti, Luciano, Biffo, Stefano

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