Therapeutic approaches to enhance PINK1/Parkin mediated mitophagy for the treatment of Parkinson’s disease von Miller, Silke, Muqit, Miratul M.K.

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Immunohistochemical localization of the calcitonin gene-related peptide binding site in the primate trigeminovascular system using functional antagonist antibodies von Miller, Silke, Liu, Hantao, Warfvinge, Karin, Shi, Licheng, Dovlatyan, Mary, Xu, Cen, Edvinsson, Lars

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Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice von Guilloux, Jean-Philippe, Mendez-David, Indira, Pehrson, Alan, Guiard, Bruno P., Repérant, Christelle, Orvoën, Sophie, Gardier, Alain M., Hen, René, Ebert, Bjarke, Miller, Silke, Sanchez, Connie, David, Denis J.

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Effects of monoclonal antagonist antibodies on calcitonin gene-related peptide receptor function and trafficking von Manoukian, Raffi, Sun, Hong, Miller, Silke, Shi, Di, Chan, Brian, Xu, Cen

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Effects of CYP46A1 Inhibition on Long-Term-Depression in Hippocampal Slices ex vivo and 24S-Hydroxycholesterol Levels in Mice in vivo von Popiolek, Michael, Izumi, Yukitoshi, Hopper, Allen T., Dai, Jing, Miller, Silke, Shu, Hong-Jin, Zorumski, Charles F., Mennerick, Steven

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Does inactivation of USP14 enhance degradation of proteasomal substrates that are associated with neurodegenerative diseases? [version 2; peer review: 3 approved] von Ortuno, Daniel, Carlisle, Holly J, Miller, Silke

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Antibodies to the extracellular pore loop of TRPM8 act as antagonists of channel activation von Miller, Silke, Rao, Sara, Wang, Weiya, Liu, Hantao, Wang, Judy, Gavva, Narender R

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Radiosynthesis and initial characterization of a PDE10A specific PET tracer [18 F]AMG 580 in non-human primates von Hwang, Dah-Ren, Hu, Essa, Allen, Jennifer R, Davis, Carl, Treanor, James, Miller, Silke, Chen, Hang, Shi, Bingzhi, Narayanan, Tanjorie K, Barret, Olivier, Alagille, David, Yu, Zhigang, Slifstein, Mark

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Rapid Identification of a Novel Small Molecule Phosphodiesterase 10A (PDE10A) Tracer von Hu, Essa, Ma, Ji, Biorn, Christopher, Lester-Zeiner, Dianna, Cho, Robert, Rumfelt, Shannon, Kunz, Roxanne K, Nixey, Thomas, Michelsen, Klaus, Miller, Silke, Shi, Jianxia, Wong, Jamie, Hill Della Puppa, Geraldine, Able, Jessica, Talreja, Santosh, Hwang, Dah-Ren, Hitchcock, Stephen A, Porter, Amy, Immke, David, Allen, Jennifer R, Treanor, James, Chen, Hang

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Does inactivation of USP14 enhance degradation of proteasomal substrates that are associated with neurodegenerative diseases? von Ortuno, Daniel, Carlisle, Holly J., Miller, Silke

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Vortioxetine (Lu AA21004), a novel multimodal antidepressant, enhances memory in rats von Mørk, Arne, Montezinho, Liliana P., Miller, Silke, Trippodi-Murphy, Crista, Plath, Niels, Li, Yan, Gulinello, Maria, Sanchez, Connie

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PAC1 receptor mRNA and protein distribution in rat and human trigeminal and sphenopalatine ganglia, spinal trigeminal nucleus and in dura mater von Hensley, Kelly, Pretorius, Jim, Chan, Brian, Page, Keith, Liu, Hantao, Choi, Chang, Shi, Di, Xu, Cen, Edvinsson, Lars, Miller, Silke

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Small molecule therapeutics for neuroinflammation-mediated neurodegenerative disorders von Miller, Silke, Blanco, Maria-Jesus

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The Novel Neuropeptide Y Y5 Receptor Antagonist Lu AA33810 [N-[[trans-4-[(4,5-Dihydro[1]benzothiepino[5,4-d]thiazol-2-yl)amino]cyclohexyl]methyl]-methanesulfonamide] Exerts Anxioly... von Walker, Mary W., Wolinsky, Toni D., Jubian, Vrej, Chandrasena, Gamini, Zhong, Huailing, Huang, Xinyan, Miller, Silke, Hegde, Laxminarayan G., Marsteller, Douglas A., Marzabadi, Mohammad R., Papp, Mariusz, Overstreet, David H., Gerald, Christophe P.G., Craig, Douglas A.

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PAC1 receptor blockade reduces central nociceptive activity: new approach for primary headache? von Hoffmann, Jan, Miller, Silke, Martins-Oliveira, Margarida, Akerman, Simon, Supronsinchai, Weera, Sun, Hong, Shi, Licheng, Wang, Judy, Zhu, Dawn, Lehto, Sonya, Liu, Hantao, Yin, Ruoyuan, Moyer, Bryan D., Xu, Cen, Goadsby, Peter J.

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AMG 580: A Novel Small Molecule Phosphodiesterase 10A (PDE10A) Positron Emission Tomography Tracer von Chen, Hang, Lester-Zeiner, Dianna, Shi, Jianxia, Miller, Silke, Glaus, Charlie, Hu, Essa, Chen, Ning, Able, Jessica, Biorn, Christopher, Wong, Jamie, Ma, Ji, Michelsen, Klaus, Hill Della Puppa, Geraldine, Kazules, Tim, Dou, Hui Hannah, Talreja, Santosh, Zhao, Xiaoning, Chen, Ada, Rumfelt, Shannon, Kunz, Roxanne K., Ye, Hu, Thiel, Oliver R., Williamson, Toni, Davis, Carl, Porter, Amy, Immke, David, Allen, Jennifer R., Treanor, James

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The effects of acute treatment with escitalopram on the different stages of contextual fear conditioning are reversed by atomoxetine von Montezinho, Liliana P., Miller, Silke, Plath, Niels, Jensen, Nanna Hovelsø, Karlsson, Jens-Jakob, Witten, Louise, Mørk, Arne

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Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility von Rzasa, Robert M., Frohn, Michael J., Andrews, Kristin L., Chmait, Samer, Chen, Ning, Clarine, Jeffrey G., Davis, Carl, Eastwood, Heather A., Horne, Daniel B., Hu, Essa, Jones, Adrie D., Kaller, Matthew R., Kunz, Roxanne K., Miller, Silke, Monenschein, Holger, Nguyen, Thomas, Pickrell, Alexander J., Porter, Amy, Reichelt, Andreas, Zhao, Xiaoning, Treanor, James J.S., Allen, Jennifer R.

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Characterization of [ 3H]Lu AE60157 ([ 3H]8-(4-methylpiperazin-1-yl)-3-phenylsulfonylquinoline) binding to 5-hydroxytryptamine 6 (5-HT 6) receptors in vivo von Witten, Louise, Bang-Andersen, Benny, Nielsen, Søren Møller, Miller, Silke, Christoffersen, Claus Tornby, Stensbøl, Tine Bryan, Brennum, Lise Tøttrup, Arnt, Jørn

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Discovery of Novel Imidazo[4,5‑b]pyridines as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A) von Hu, Essa, Andrews, Kristin, Chmait, Samer, Zhao, Xiaoning, Davis, Carl, Miller, Silke, Hill Della Puppa, Geraldine, Dovlatyan, Mary, Chen, Hang, Lester-Zeiner, Dianna, Able, Jessica, Biorn, Christopher, Ma, Ji, Shi, Jianxia, Treanor, James, Allen, Jennifer R

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