In vivo genome editing of the albumin locus as a platform for protein replacement therapy von Sharma, Rajiv, Anguela, Xavier M., Doyon, Yannick, Wechsler, Thomas, DeKelver, Russell C., Sproul, Scott, Paschon, David E., Miller, Jeffrey C., Davidson, Robert J., Shivak, David, Zhou, Shangzhen, Rieders, Julianne, Gregory, Philip D., Holmes, Michael C., Rebar, Edward J., High, Katherine A.

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Non-viral Delivery of Zinc Finger Nuclease mRNA Enables Highly Efficient In Vivo Genome Editing of Multiple Therapeutic Gene Targets von Conway, Anthony, Mendel, Matthew, Kim, Kenneth, McGovern, Kyle, Boyko, Alisa, Zhang, Lei, Miller, Jeffrey C., DeKelver, Russell C., Paschon, David E., Mui, Barbara L., Lin, Paulo J.C., Tam, Ying K., Barbosa, Chris, Redelmeier, Tom, Holmes, Michael C., Lee, Gary

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Targeted Genome Editing Across Species Using ZFNs and TALENs von Wood, Andrew J., Lo, Te-Wen, Zeitler, Bryan, Pickle, Catherine S., Ralston, Edward J., Lee, Andrew H., Amora, Rainier, Miller, Jeffrey C., Leung, Elo, Meng, Xiangdong, Zhang, Lei, Rebar, Edward J., Gregory, Philip D., Urnov, Fyodor D., Meyer, Barbara J.

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Diversifying the structure of zinc finger nucleases for high-precision genome editing von Paschon, David E., Lussier, Stephanie, Wangzor, Tenzin, Xia, Danny F., Li, Patrick W., Hinkley, Sarah J., Scarlott, Nicholas A., Lam, Stephen C., Waite, Adam J., Truong, Lynn N., Gandhi, Nimisha, Kadam, Bhakti N., Patil, Deepak P., Shivak, David A., Lee, Gary K., Holmes, Michael C., Zhang, Lei, Miller, Jeffrey C., Rebar, Edward J.

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Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases von Amora, Ranier, Miller, Jeffrey C, Mitalipova, Maisam, Katibah, George E, Rebar, Edward J, Urnov, Fyodor D, Jaenisch, Rudolf, Gregory, Philip D, Boydston, Elizabeth A, Beard, Caroline, Hockemeyer, Dirk, Zeitler, Bryan, Meng, Xiangdong, Soldner, Frank, Gao, Qing, Zhang, Lei, DeKelver, Russell C

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A Rapid and General Assay for Monitoring Endogenous Gene Modification von Guschin, Dmitry Y., Waite, Adam J., Katibah, George E., Miller, Jeffrey C., Holmes, Michael C., Rebar, Edward J.

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Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions von Goldberg, Aaron D., Banaszynski, Laura A., Noh, Kyung-Min, Lewis, Peter W., Elsaesser, Simon J., Stadler, Sonja, Dewell, Scott, Law, Martin, Guo, Xingyi, Li, Xuan, Wen, Duancheng, Chapgier, Ariane, DeKelver, Russell C., Miller, Jeffrey C., Lee, Ya-Li, Boydston, Elizabeth A., Holmes, Michael C., Gregory, Philip D., Greally, John M., Rafii, Shahin, Yang, Chingwen, Scambler, Peter J., Garrick, David, Gibbons, Richard J., Higgs, Douglas R., Cristea, Ileana M., Urnov, Fyodor D., Zheng, Deyou, Allis, C. David

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Toward eliminating HLA class I expression to generate universal cells from allogeneic donors von Torikai, Hiroki, Reik, Andreas, Soldner, Frank, Warren, Edus H., Yuen, Carrie, Zhou, Yuanyue, Crossland, Denise L., Huls, Helen, Littman, Nicholas, Zhang, Ziying, Tykodi, Scott S., Kebriaei, Partow, Lee, Dean A., Miller, Jeffrey C., Rebar, Edward J., Holmes, Michael C., Jaenisch, Rudolf, Champlin, Richard E., Gregory, Philip D., Cooper, Laurence J.N.

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Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases von Geurts, Aron M, Cost, Gregory J, Freyvert, Yevgeniy, Zeitler, Bryan, Miller, Jeffrey C, Choi, Vivian M, Jenkins, Shirin S, Wood, Adam, Cui, Xiaoxia, Meng, Xiangdong, Vincent, Anna, Lam, Stephen, Michalkiewicz, Mieczyslaw, Schilling, Rebecca, Foeckler, Jamie, Kalloway, Shawn, Weiler, Hartmut, Ménoret, Séverine, Anegon, Ignacio, Davis, Gregory D, Zhang, Lei, Rebar, Edward J, Gregory, Philip D, Urnov, Fyodor D, Jacob, Howard J, Buelow, Roland

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Robust ZFN-mediated genome editing in adult hemophilic mice von Anguela, Xavier M., Sharma, Rajiv, Doyon, Yannick, Miller, Jeffrey C., Li, Hojun, Haurigot, Virginia, Rohde, Michelle E., Wong, Sunnie Y., Davidson, Robert J., Zhou, Shangzhen, Gregory, Philip D., Holmes, Michael C., High, Katherine A.

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An improved zinc-finger nuclease architecture for highly specific genome editing von Wang, Jianbin, Rebar, Edward J, Guschin, Dmitry Y, Lee, Ya-Li, Holmes, Michael C, Miller, Jeffrey C, Gregory, Philip D, Kim, Kenneth A, Waite, Adam J, Beausejour, Christian M, Wang, Nathaniel S, Pabo, Carl O, Rupniewski, Igor

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Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells von Drubin, David G, Lee, Andrew H, Cheng, Aaron T, Doyon, Yannick, Vo, Thuy D, Miller, Jeffrey C, Cherone, Jennifer M, Cheng, Jackie, Santiago, Yolanda, Urnov, Fyodor D, Paschon, David E, Doyon, Jeffrey B, Zhang, Lei, Rebar, Edward J, Gregory, Philip D, Zeitler, Bryan

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Precise genome modification in the crop species Zea mays using zinc-finger nucleases von Shukla, Vipula K, Doyon, Yannick, Miller, Jeffrey C, DeKelver, Russell C, Moehle, Erica A, Worden, Sarah E, Mitchell, Jon C, Arnold, Nicole L, Gopalan, Sunita, Meng, Xiangdong, Choi, Vivian M, Rock, Jeremy M, Wu, Ying-Ying, Katibah, George E, Zhifang, Gao

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Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme von Wang, Jianbin, Friedman, Geoffrey, Doyon, Yannick, Wang, Nathaniel S, Li, Carrie Jiaxin, Miller, Jeffrey C, Hua, Kevin L, Yan, Jenny Jiacheng, Babiarz, Joshua E, Gregory, Philip D, Holmes, Michael C

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Development of a single-chain, quasi-dimeric zinc-finger nuclease for the selective degradation of mutated human mitochondrial DNA von Minczuk, Michal, Papworth, Monika A, Miller, Jeffrey C, Murphy, Michael P, Klug, Aaron

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Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases von Santiago, Yolanda, Chan, Edmond, Liu, Pei-Qi, Orlando, Salvatore, Zhang, Lin, Urnov, Fyodor D, Holmes, Michael C, Guschin, Dmitry, Waite, Adam, Miller, Jeffrey C, Rebar, Edward J, Gregory, Philip D, Klug, Aaron, Collingwood, Trevor N

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Compact zinc finger architecture utilizing toxin-derived cytidine deaminases for highly efficient base editing in human cells von Fauser, Friedrich, Kadam, Bhakti N., Arangundy-Franklin, Sebastian, Davis, Jessica E., Vaidya, Vishvesha, Schmidt, Nicola J., Lew, Garrett, Xia, Danny F., Mureli, Rakshaa, Ng, Colman, Zhou, Yuanyue, Scarlott, Nicholas A., Eshleman, Jason, Bendaña, Yuri R., Shivak, David A., Reik, Andreas, Li, Patrick, Davis, Gregory D., Miller, Jeffrey C.

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Improved specificity of TALE-based genome editing using an expanded RVD repertoire von Miller, Jeffrey C, Zhang, Lei, Xia, Danny F, Campo, John J, Ankoudinova, Irina V, Guschin, Dmitry Y, Babiarz, Joshua E, Meng, Xiangdong, Hinkley, Sarah J, Lam, Stephen C, Paschon, David E, Vincent, Anna I, Dulay, Gladys P, Barlow, Kyle A, Shivak, David A, Leung, Elo, Kim, Jinwon D, Amora, Rainier, Urnov, Fyodor D, Gregory, Philip D, Rebar, Edward J

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Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases von Young, John J, Cherone, Jennifer M, Doyon, Yannick, Ankoudinova, Irina, Faraji, Farhoud M, Lee, Andrew H, Ngo, Catherine, Guschin, Dmitry Y, Paschon, David E, Miller, Jeffrey C, Zhang, Lei, Rebar, Edward J, Gregory, Philip D, Urnov, Fyodor D, Harland, Richard M, Zeitler, Bryan

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Persistent repression of tau in the brain using engineered zinc finger protein transcription factors von Wegmann, Susanne, DeVos, Sarah L, Zeitler, Bryan, Marlen, Kimberly, Bennett, Rachel E, Perez-Rando, Marta, MacKenzie, Danny, Yu, Qi, Commins, Caitlin, Bannon, Riley N, Corjuc, Bianca T, Chase, Alison, Diez, Lisa, Nguyen, Hoang-Oanh B, Hinkley, Sarah, Zhang, Lei, Goodwin, Alicia, Ledeboer, Annemarie, Lam, Stephen, Ankoudinova, Irina, Tran, Hung, Scarlott, Nicholas, Amora, Rainier, Surosky, Richard, Miller, Jeffrey C, Robbins, Ashley B, Rebar, Edward J, Urnov, Fyodor D, Holmes, Michael C, Pooler, Amy M, Riley, Brigit, Zhang, H Steve, Hyman, Bradley T

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