mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype von Herranz, Nicolás, Gallage, Suchira, Mellone, Massimiliano, Wuestefeld, Torsten, Klotz, Sabrina, Hanley, Christopher J., Raguz, Selina, Acosta, Juan Carlos, Innes, Andrew J., Banito, Ana, Georgilis, Athena, Montoya, Alex, Wolter, Katharina, Dharmalingam, Gopuraja, Faull, Peter, Carroll, Thomas, Martínez-Barbera, Juan Pedro, Cutillas, Pedro, Reisinger, Florian, Heikenwalder, Mathias, Miller, Richard A., Withers, Dominic, Zender, Lars, Thomas, Gareth J., Gil, Jesús

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Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice von Smith, Byron J, Miller, Richard A, Ericsson, Aaron C, Harrison, David C, Strong, Randy, Schmidt, Thomas M

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Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions von Petkovich, Daniel A, Podolskiy, Dmitriy I, Lobanov, Alexei V, Lee, Sang-Goo, Miller, Richard A, Gladyshev, Vadim N

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Reduced Expression of MYC Increases Longevity and Enhances Healthspan von Hofmann, Jeffrey W., Zhao, Xiaoai, De Cecco, Marco, Peterson, Abigail L., Pagliaroli, Luca, Manivannan, Jayameenakshi, Hubbard, Gene B., Ikeno, Yuji, Zhang, Yongqing, Feng, Bin, Li, Xiaxi, Serre, Thomas, Qi, Wenbo, Van Remmen, Holly, Miller, Richard A., Bath, Kevin G., de Cabo, Rafael, Xu, Haiyan, Neretti, Nicola, Sedivy, John M.

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Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy von Honigberg, Lee A, Smith, Ashley M, Sirisawad, Mint, Verner, Erik, Loury, David, Chang, Betty, Li, Shyr, Pan, Zhengying, Thamm, Douglas H, Miller, Richard A, Buggy, Joseph J

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Muribaculaceae Genomes Assembled from Metagenomes Suggest Genetic Drivers of Differential Response to Acarbose Treatment in Mice von Smith, Byron J, Miller, Richard A, Schmidt, Thomas M

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Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions von Cole, John J, Robertson, Neil A, Rather, Mohammed Iqbal, Thomson, John P, McBryan, Tony, Sproul, Duncan, Wang, Tina, Brock, Claire, Clark, William, Ideker, Trey, Meehan, Richard R, Miller, Richard A, Brown-Borg, Holly M, Adams, Peter D

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Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction von Miller, Richard A., Harrison, David E., Astle, Clinton M., Fernandez, Elizabeth, Flurkey, Kevin, Han, Melissa, Javors, Martin A., Li, Xinna, Nadon, Nancy L., Nelson, James F., Pletcher, Scott, Salmon, Adam B., Sharp, Zelton Dave, Van Roekel, Sabrina, Winkleman, Lynn, Strong, Randy

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Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer von Fong, Lawrence, Hotson, Andrew, Powderly, John D, Sznol, Mario, Heist, Rebecca S, Choueiri, Toni K, George, Saby, Hughes, Brett G M, Hellmann, Matthew D, Shepard, Dale R, Rini, Brian I, Kummar, Shivaani, Weise, Amy M, Riese, Matthew J, Markman, Ben, Emens, Leisha A, Mahadevan, Daruka, Luke, Jason J, Laport, Ginna, Brody, Joshua D, Hernandez-Aya, Leonel, Bonomi, Philip, Goldman, Jonathan W, Berim, Lyudmyla, Renouf, Daniel J, Goodwin, Rachel A, Munneke, Brian, Ho, Po Y, Hsieh, Jessica, McCaffery, Ian, Kwei, Long, Willingham, Stephen B, Miller, Richard A

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice von Nelson, James F, Carter, Christy S, Pahor, Marco, Frenkel, Krystyna, Miller, Richard A, Nadon, Nancy L, Wilkinson, J. Erby, Fernandez, Elizabeth, Javors, Martin A, Flurkey, Kevin, Astle, Clinton M, Sharp, Zelton Dave, Harrison, David E, Strong, Randy

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Not Your Father's, or Mother's, Rodent: Moving Beyond B6 von Miller, Richard A.

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Rapamycin slows aging in mice von Wilkinson, John E., Burmeister, Lisa, Brooks, Susan V., Chan, Chi‐Chao, Friedline, Sabrina, Harrison, David E., Hejtmancik, James F., Nadon, Nancy, Strong, Randy, Wood, Lauren K., Woodward, Maria A., Miller, Richard A.

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Nrf2 Signaling, a Mechanism for Cellular Stress Resistance in Long-Lived Mice von Leiser, Scott F., Miller, Richard A.

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mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism von Tang, Huibin, Inoki, Ken, Brooks, Susan V., Okazawa, Hideki, Lee, Myung, Wang, Junying, Kim, Michael, Kennedy, Catherine L., Macpherson, Peter C. D., Ji, Xuhuai, Van Roekel, Sabrina, Fraga, Danielle A., Wang, Kun, Zhu, Jinguo, Wang, Yoyo, Sharp, Zelton D., Miller, Richard A., Rando, Thomas A., Goldman, Daniel, Guan, Kun‐Liang, Shrager, Joseph B.

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Elevated ATF4 function in fibroblasts and liver of slow-aging mutant mice von Li, Weiquan, Miller, Richard A

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PTEN is both an activator and a substrate of chaperone-mediated autophagy von Zhang, Katherine K, Burns, Calvin M, Skinner, Mary E, Lombard, David B, Miller, Richard A, Endicott, S Joseph

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Aging is associated with increased brain iron through cortex-derived hepcidin expression von Sato, Tatsuya, Shapiro, Jason Solomon, Chang, Hsiang-Chun, Miller, Richard A, Ardehali, Hossein

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Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle von Zhao, Yang, Zheng, Zhizhong, Zhang, Zhihui, Xu, Yandong, Hillpot, Eric, Lin, Yifei S., Zakusilo, Frances T., Lu, J. Yuyang, Ablaeva, Julia, Biashad, Seyed Ali, Miller, Richard A., Nevo, Eviatar, Seluanov, Andrei, Gorbunova, Vera

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Organization of the Mammalian Metabolome according to Organ Function, Lineage Specialization, and Longevity von Ma, Siming, Yim, Sun Hee, Lee, Sang-Goo, Kim, Eun Bae, Lee, Sang-Rae, Chang, Kyu-Tae, Buffenstein, Rochelle, Lewis, Kaitlyn N., Park, Thomas J., Miller, Richard A., Clish, Clary B., Gladyshev, Vadim N.

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A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing von Lu, Yu-Xuan, Regan, Jennifer C, Eßer, Jacqueline, Drews, Lisa F, Weinseis, Thomas, Stinn, Julia, Hahn, Oliver, Miller, Richard A, Grönke, Sebastian, Partridge, Linda

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