Developing an atroposelective dynamic kinetic resolution of MRTX1719 by resolving incompatible chemical operations von Achmatowicz, Michal M, Chen, Cheng-yi, Snead, David R

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Implementing Continuous Manufacturing for the Final Methylation Step in the AMG 397 Process to Deliver Key Quality Attributes von Tom, Janine K, Achmatowicz, Michal M, Beaver, Matthew G, Colyer, John, Ericson, Ari, Hwang, Tsang-Lin, Jiao, Nancy, Langille, Neil F, Liu, Min, Lovette, Michael A, Sangodkar, Rahul P, Sharvan Kumar, Srividya, Spada, Simone, Perera, Damith, Sheeran, Jillian, Campbell, Kiersten, Doherty, Timothy, Ford, David D, Fang, Yuan-Qing, Rossi, Emiliano, Santoni, Gabriella, Cui, Sheng, Walker, Shawn D

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Palladium-Catalyzed Chemoselective Monoarylation of Hydrazides for the Synthesis of [1,2,4]Triazolo[4,3-a]pyridines von Reichelt, Andreas, Falsey, James R, Rzasa, Robert M, Thiel, Oliver R, Achmatowicz, Michal M, Larsen, Robert D, Zhang, Dawei

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Hydrolysis of Phosphoryl Trichloride (POCl3): Characterization, in Situ Detection, and Safe Quenching of Energetic Metastable Intermediates von Achmatowicz, Michał M, Thiel, Oliver R, Colyer, John T, Hu, Jack, Elipe, Maria Victoria Silva, Tomaskevitch, Joe, Tedrow, Jason S, Larsen, Robert D

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Telescoped Process to Manufacture 6,6,6-Trifluorofucose via Diastereoselective Transfer Hydrogenation: Scalable Access to an Inhibitor of Fucosylation Utilized in Monoclonal Antibo... von Achmatowicz, Michal M, Allen, John G, Bio, Matthew M, Bartberger, Michael D, Borths, Christopher J, Colyer, John T, Crockett, Richard D, Hwang, Tsang-Lin, Koek, Jan. N, Osgood, Stephen A, Roberts, Scott W, Swietlow, Aleksander, Thiel, Oliver R, Caille, Seb

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Palladium-Catalyzed Coupling of Aldehyde-Derived Hydrazones: Practical Synthesis of Triazolopyridines and Related Heterocycles von Thiel, Oliver R., Achmatowicz, Michal M., Reichelt, Andreas, Larsen, Robert D.

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Practical Synthesis of a p38 MAP Kinase Inhibitor von Achmatowicz, Michał, Thiel, Oliver R, Wheeler, Philip, Bernard, Charles, Huang, Jinkun, Larsen, Robert D, Faul, Margaret M

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Development of a Practical Synthesis of a p38 MAP Kinase Inhibitor von Thiel, Oliver R, Achmatowicz, Michal, Bernard, Charles, Wheeler, Philip, Savarin, Cecile, Correll, Tiffany L, Kasparian, Annie, Allgeier, Alan, Bartberger, Michael D, Tan, Helming, Larsen, Robert D

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The synthesis of l-proline derived tetraazamacrocyclic ligands of C2 symmetry via intramolecular ester aminolysis von Achmatowicz, Michał, Jurczak, Janusz

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Scalable Atroposelective Synthesis of MRTX1719: An Inhibitor of the PRMT5/MTA Complex von Achmatowicz, Michal, Scattolin, Thomas, Snead, David R., Paymode, Dinesh J., Roshandel, Sahar, Xie, Chen, Chen, Guihui, Chen, Cheng-yi

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A simple synthesis of chiral macrocyclic tetraamides derived from α-amino acids von Zieliński, Tomasz, Achmatowicz, Michał, Jurczak, Janusz

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Development of Adagrasib’s Commercial Manufacturing Route von Snead, David R., Gan, Yonghong, Scattolin, Thomas, Paymode, Dinesh J., Achmatowicz, Michal, Rudisill, Duane E., Vidal, Ephraim S., Gharbaoui, Tawfik, Roberts, Phil, Yang, Jianbo, Shi, Zhangbing, Liu, Wei, Bolger, Joshua, Qiao, Zhen, Chen, Cheng-yi

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The synthesis of l-proline derived hexaazamacrocyclic ligands of C3 symmetry via intramolecular methyl ester aminolysis von Achmatowicz, Michał, Jurczak, Janusz

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Selective Ortho Methylation of Nitroheteroaryls by Vicarious Nucleophilic Substitution von Achmatowicz, Michał, Thiel, Oliver R, Gorins, Gilles, Goldstein, Corinne, Affouard, Caroline, Jensen, Randy, Larsen, Robert D

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Synthesis of 1-Deoxy-d-galactohomonojirimycin via Enantiomerically Pure Allenylstannanes von Achmatowicz, Michal, Hegedus, Louis S

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Palladium‐Catalyzed Coupling of Aldehyde‐Derived Hydrazones: Practical Synthesis of Triazolopyridines and Related Heterocycles von Thiel, Oliver R., Achmatowicz, Michal M., Reichelt, Andreas, Larsen, Robert D.

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Titelbild: Palladium-Catalyzed Coupling of Aldehyde-Derived Hydrazones: Practical Synthesis of Triazolopyridines and Related Heterocycles (Angew. Chem. 45/2010) von Thiel, Oliver R., Achmatowicz, Michal M., Reichelt, Andreas, Larsen, Robert D.

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Palladium-Catalyzed Triazolopyridine Synthesis: Synthesis of 7-Chloro-3-(2-Chlorophenyl)-1,2,4-Triazolo[4,3-a]Pyridine

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Cover Picture: Palladium-Catalyzed Coupling of Aldehyde-Derived Hydrazones: Practical Synthesis of Triazolopyridines and Related Heterocycles (Angew. Chem. Int. Ed. 45/2010) von Thiel, Oliver R., Achmatowicz, Michal M., Reichelt, Andreas, Larsen, Robert D.

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Palladium‐Catalyzed Coupling of Aldehyde‐Derived Hydrazones: Practical Synthesis of Triazolopyridines and Related Heterocycles von Thiel, Oliver R., Achmatowicz, Michal M., Reichelt, Andreas, Larsen, Robert D.

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