PDE8 regulates rapid Teff cell adhesion and proliferation independent of ICER von Vang, Amanda G, Ben-Sasson, Shlomo Z, Dong, Hongli, Kream, Barbara, DeNinno, Michael P, Claffey, Michelle M, Housley, William, Clark, Robert B, Epstein, Paul M, Brocke, Stefan

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Activation of the G-Protein-Coupled Receptor 119: A Conformation-Based Hypothesis for Understanding Agonist Response von McClure, Kim F, Darout, Etzer, Guimarães, Cristiano R. W, DeNinno, Michael P, Mascitti, Vincent, Munchhof, Michael J, Robinson, Ralph P, Kohrt, Jeffrey, Harris, Anthony R, Moore, Dianna E, Li, Bryan, Samp, Lacey, Lefker, Bruce A, Futatsugi, Kentaro, Kung, Daniel, Bonin, Paul D, Cornelius, Peter, Wang, Ruduan, Salter, Eben, Hornby, Sam, Kalgutkar, Amit S, Chen, Yue

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Future directions in phosphodiesterase drug discovery von DeNinno, Michael P.

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The discovery of potent, selective, and orally bioavailable PDE9 inhibitors as potential hypoglycemic agents von DeNinno, Michael P., Andrews, Melissa, Bell, Andrew S., Chen, Yue, Eller-Zarbo, Cynthia, Eshelby, Nan, Etienne, John B., Moore, Dianna E., Palmer, Michael J., Visser, Michael S., Yu, Li J., Zavadoski, William J., Michael Gibbs, E.

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Synthesis of Fused Bicyclic Piperidines: Potential Bioactive Templates for Medicinal Chemistry von Zhou, Jinglan, Campbell-Conroy, Erica L, Silina, Alina, Uy, Johnny, Pierre, Fabrice, Hurley, Dennis J, Hilgraf, Nicole, Frieman, Bryan A, DeNinno, Michael P

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The Preparation and Intra- and Intermolecular Addition Reactions of Acyclic N-Acylimines:  Application to the Synthesis of (±)-Sertraline von DeNinno, Michael P, Eller, Cynthia, Etienne, John B

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From partial to full agonism: Identification of a novel 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole as a full agonist of the human GPR119 receptor von Futatsugi, Kentaro, Mascitti, Vincent, Guimarães, Cristiano R.W., Morishita, Nao, Cai, Cuiman, DeNinno, Michael P., Gao, Hua, Hamilton, Michael D., Hank, Richard, Harris, Anthony R., Kung, Daniel W., Lavergne, Sophie Y., Lefker, Bruce A., Lopaze, Michael G., McClure, Kim F., Munchhof, Michael J., Preville, Cathy, Robinson, Ralph P., Wright, Stephen W., Bonin, Paul D., Cornelius, Peter, Chen, Yue, Kalgutkar, Amit S.

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1,5-Substituted nipecotic amides: Selective PDE8 inhibitors displaying diastereomer-dependent microsomal stability von DeNinno, Michael P., Wright, Stephen W., Visser, Michael S., Etienne, John B., Moore, Dianna E., Olson, Thanh V., Rocke, Benjamin N., Andrews, Melissa P., Zarbo, Cynthia, Millham, Michele L., Boscoe, Brian P., Boyer, David D., Doran, Shawn D., Houseknecht, Karen L.

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Discovery of triazolopyrimidine-based PDE8B inhibitors: Exceptionally ligand-efficient and lipophilic ligand-efficient compounds for the treatment of diabetes von DeNinno, Michael P., Wright, Stephen W., Etienne, John B., Olson, Thanh V., Rocke, Benjamin N., Corbett, Jeffrey W., Kung, Daniel W., DiRico, Kenneth J., Andrews, Kim M., Millham, Michele L., Parker, Janice C., Esler, William, van Volkenburg, Maria, Boyer, David D., Houseknecht, Karen L., Doran, Shawn D.

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Differing cardioprotective efficacy of the Na+/Ca2+ exchanger inhibitors SEA0400 and KB-R7943 von Magee, William P, Deshmukh, Gayatri, Deninno, Michael P, Sutt, Jill C, Chapman, Justin G, Tracey, W. Ross

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A method for the selective reduction of carbohydrate 4,6- O-benzylidene acetals von DeNinno, Michael P., Etienne, John B., Duplantier, Kimberly C.

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Stereoselective total syntheses of the naturally occurring enantiomers of N-acetylneuraminic acid and 3-deoxy-D-manno-2-octulosonic acid. A new and stereospecific approach to sialo... von Danishefsky, Samuel J, DeNinno, Michael P, Chen, Shu Hui

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3‘-Aminoadenosine-5‘-uronamides:  Discovery of the First Highly Selective Agonist at the Human Adenosine A3 Receptor von DeNinno, Michael P, Masamune, Hiroko, Chenard, Lois K, DiRico, Kenneth J, Eller, Cynthia, Etienne, John B, Tickner, Jeanene E, Kennedy, Scott P, Knight, Delvin R, Kong, Jimmy, Oleynek, Joseph J, Tracey, W. Ross, Hill, Roger J

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Synthesis and dopaminergic activity of 3-substituted 1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-1H-2-benzopyrans: characterization of an auxiliary binding region in the D1 receptor von DeNinno, Michael P, Schoenleber, Robert, Perner, Richard J, Lijewski, Linda, Asin, Karen E, Britton, Donald R, MacKenzie, Robert, Kebabian, John W

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The synthesis of highly potent, selective, and water-soluble agonists at the human adenosine A3 receptor von DENINNO, Michael P, MASAMUNE, Hiroko, OLEYNEK, Joseph J, TRACEY, W. Ross, HILL, Roger J, CHENARD, Lois K, DIRICO, Kenneth J, ELLER, Cynthia, ETIENNE, John B, TICKNER, Jeanene E, KENNEDY, Scott P, KNIGHT, Delvin R, KONG, Jimmy

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Comparison of synthetic saponin cholesterol absorption inhibitors in rabbits: evidence for a non-stoichiometric, intestinal mechanism of action von Morehouse, L.A, Bangerter, F.W, DeNinno, M.P, Inskeep, P.B, McCarthy, P.A, Pettini, J.L, Savoy, Y.E, Sugarman, E.D, Wilkins, R.W, Wilson, T.C

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"Anomalous" Ozonolysis of Cyclic Allylic Alcohols: Mechanism and Synthetic Utility von DeNinno, Michael P

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Efficient generation and intramolecular cyclization reactions of acyl imines von DeNinno, Michael P., Eller, Cynthia

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The total synthesis of (.+-.)-N-acetylneuraminic acid (NANA). A remarkable hydroxylation of a (Z)-enoate von Danishefsky, Samuel J, DeNinno, Michael P

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Steroidal Glycoside Cholesterol Absorption Inhibitors von DeNinno, Michael P, McCarthy, Peter A, Duplantier, Kimberly C, Eller, Cynthia, Etienne, John B, Zawistoski, Michael P, Bangerter, Faan Wen, Chandler, Charles E, Morehouse, Lee A, Sugarman, Eliot D, Wilkins, Robert W, Woody, Heidi A, Zaccaro, Lawrence M

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