The role of anaerobic sludge recycle in improving anaerobic digester performance von Young, Michelle N., Krajmalnik-Brown, Rosa, Liu, Wenjun, Doyle, Michael L., Rittmann, Bruce E.

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The structure of the death receptor 4-TNF-related apoptosis-inducing ligand (DR4-TRAIL) complex von Ramamurthy, Vidhyashankar, Yamniuk, Aaron P., Lawrence, Eric J., Yong, Wei, Schneeweis, Lumelle A., Cheng, Lin, Murdock, Melissa, Corbett, Martin J., Doyle, Michael L., Sheriff, Steven

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Mutagenic Stabilization and/or Disruption of a CD4-Bound State Reveals Distinct Conformations of the Human Immunodeficiency Virus Type 1 gp120 Envelope Glycoprotein von Xiang, Shi-Hua, Kwong, Peter D, Gupta, Rishi, Rizzuto, Carlo D, Casper, David J, Wyatt, Richard, Wang, Liping, Hendrickson, Wayne A, Doyle, Michael L, Sodroski, Joseph

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A fibronectin scaffold approach to bispecific inhibitors of epidermal growth factor receptor and insulin-like growth factor-I receptor von Emanuel, Stuart L., Engle, Linda J., Chao, Ginger, Zhu, Rong-Rong, Cao, Carolyn, Lin, Zheng, Yamniuk, Aaron P., Hosbach, Jennifer, Brown, Jennifer, Fitzpatrick, Elizabeth, Gokemeijer, Jochem, Morin, Paul, Morse, Brent A., Carvajal, Irvith M., Fabrizio, David, Wright, Martin C., Das Gupta, Ruchira, Gosselin, Michael, Cataldo, Daniel, Ryseck, Rolf P., Doyle, Michael L., Wong, Tai W., Camphausen, Raymond T., Cload, Sharon T., Marsh, H. Nicholas, Gottardis, Marco M., Furfine, Eric S.

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Molecular Basis for Increased Susceptibility of Isolates with Atazanavir Resistance-Conferring Substitution I50L to Other Protease Inhibitors von Yanchunas, Jr, Joseph, Langley, David R, Tao, Li, Rose, Ronald E, Friborg, Jacques, Colonno, Richard J, Doyle, Michael L

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HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites von Kwong, Peter D., Doyle, Michael L., Casper, David J., Cicala, Claudia, Leavitt, Stephanie A., Majeed, Shahzad, Steenbeke, Tavis D., Venturi, Miro, Chaiken, Irwin, Fung, Michael, Katinger, Hermann, Parren, Paul W. I. H., Robinson, James, Van Ryk, Donald, Wang, Liping, Burton, Dennis R., Freire, Ernesto, Wyatt, Richard, Sodroski, Joseph, Hendrickson, Wayne A., Arthos, James

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Elimination of Fc Receptor-Dependent Effector Functions of a Modified IgG4 Monoclonal Antibody to Human CD4 von Reddy, Manjula P, Kinney, Cheryl Ann S, Chaikin, Margery A, Payne, Angela, Fishman-Lobell, Jacqueline, Tsui, Ping, Dal Monte, Paul R, Doyle, Michael L, Brigham-Burke, Michael R, Anderson, Darrell, Reff, Mitchell, Newman, Roland, Hanna, Nabil, Sweet, Raymond W, Truneh, Alemseged

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Application of a Kosmotrope-Based Solubility Assay to Multiple Protein Therapeutic Classes Indicates Broad Use as a High-Throughput Screen for Protein Therapeutic Aggregation Prope... von Yamniuk, Aaron P., Ditto, Noah, Patel, Mehul, Dai, Jun, Sejwal, Preeti, Stetsko, Paul, Doyle, Michael L.

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Structural Mass Spectrometry in Protein Therapeutics Discovery von Kim, Yeoun Jin, Doyle, Michael L

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Molecular Code for Cooperativity in Hemoglobin von Ackers, Gary K., Doyle, Michael L., Myers, David, Daugherty, Margaret A.

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Steady-State Kinetic Characterization of Substrates and Metal-Ion Specificities of the Full-Length and N-Terminally Truncated Recombinant Human Methionine Aminopeptidases (Type 2) von Yang, Guang, Kirkpatrick, Robert B, Ho, Thau, Zhang, Gui-Feng, Liang, Po-Huang, Johanson, Kyung O, Casper, David J, Doyle, Michael L, Marino, Joseph P, Thompson, Scott K, Chen, Wenfang, Tew, David G, Meek, Thomas D

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Energetics of the HIV gp120-CD4 binding reaction von Myszka, D G, Sweet, R W, Hensley, P, Brigham-Burke, M, Kwong, P D, Hendrickson, W A, Wyatt, R, Sodroski, J, Doyle, M L

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Impact of Substrate Feed Patterns on Solids Reduction by the Cannibal Process von Khanthongthip, Passkorn, Novak, John T., Doyle, Michael L.

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The Influence of Adnectin Binding on the Extracellular Domain of Epidermal Growth Factor Receptor von Iacob, Roxana E., Chen, Guodong, Ahn, Joomi, Houel, Stephane, Wei, Hui, Mo, Jingjie, Tao, Li, Cohen, Daniel, Xie, Dianlin, Lin, Zheng, Morin, Paul E., Doyle, Michael L., Tymiak, Adrienne A., Engen, John R.

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Identification and Initial Characterization of Four Novel Members of the Interleukin-1 Family von Kumar, Sanjay, McDonnell, Peter C., Lehr, Ruth, Tierney, Lauren, Tzimas, Maritsa N., Griswold, Don E., Capper, Elizabeth A., Tal-Singer, Ruth, Wells, Grace I., Doyle, Michael L., Young, Peter R.

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Pyridinyl Imidazole Inhibitors of p38 Mitogen-activated Protein Kinase Bind in the ATP Site von Young, P R, McLaughlin, M M, Kumar, S, Kassis, S, Doyle, M L, McNulty, D, Gallagher, T F, Fisher, S, McDonnell, P C, Carr, S A, Huddleston, M J, Seibel, G, Porter, T G, Livi, G P, Adams, J L, Lee, J C

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Characterization of binding interactions by isothermal titration calorimetry von Doyle, Michael L

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Reversible and pH-dependent weak drug-excipient binding does not affect oral bioavailability of high dose drugs von Narang, Ajit S., Yamniuk, Aaron P., Zhang, Limin, Comezoglu, S. Nilgun, Bindra, Dilbir S., Varia, Sailesh, Doyle, Michael L., Badawy, Sherif

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Selective Binding and Oligomerization of the Murine Granulocyte Colony-stimulating Factor Receptor by a Low Molecular Weight, Nonpeptidyl Ligand von Doyle, Michael L, Tian, Shin-Shay, Miller, Stephen G, Kessler, Linda, Baker, Audrey E, Brigham-Burke, Michael R, Dillon, Susan B, Duffy, Kevin J, Keenan, Richard M, Lehr, Ruth, Rosen, Jon, Schneeweis, Lumelle A, Trill, John, Young, Peter R, Luengo, Juan I, Lamb, Peter

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Development of a Model Protein Interaction Pair as a Benchmarking Tool for the Quantitative Analysis of 2-Site Protein-Protein Interactions von Yamniuk, Aaron P, Newitt, John A, Doyle, Michael L, Arisaka, Fumio, Giannetti, Anthony M, Hensley, Preston, Myszka, David G, Schwarz, Fred P, Thomson, James A, Eisenstein, Edward

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