A first in human, safety, pharmacokinetics, and clinical activity phase I study of once weekly administration of the Hsp90 inhibitor ganetespib (STA-9090) in patients with solid ma... von Goldman, Jonathan W, Raju, Robert N, Gordon, Gregory A, El-Hariry, Iman, Teofilivici, Florentina, Vukovic, Vojo M, Bradley, Robert, Karol, Michael D, Chen, Yu, Guo, Wei, Inoue, Takayo, Rosen, Lee S

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Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: safety, pharmacokinet... von DeAngelo, Daniel J., Stone, Richard M., Heaney, Mark L., Nimer, Stephen D., Paquette, Ronald L., Klisovic, Rebecca B., Caligiuri, Michael A., Cooper, Michael R., Lecerf, Jean-Michel, Karol, Michael D., Sheng, Shihong, Holford, Nick, Curtin, Peter T., Druker, Brian J., Heinrich, Michael C.

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A phase I and pharmacokinetic study of ganetespib (STA-9090) in advanced hepatocellular carcinoma von Goyal, Lipika, Wadlow, Raymond C., Blaszkowsky, Lawrence S., Wolpin, Brian M., Abrams, Thomas A., McCleary, Nadine Jackson, Sheehan, Susan, Sundaram, Eamala, Karol, Michael D., Chen, John, Zhu, Andrew X.

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Napabucasin Drug‐Drug Interaction Potential, Safety, Tolerability, and Pharmacokinetics Following Oral Dosing in Healthy Adult Volunteers von Dai, Xiaoshu, Karol, Michael D., Hitron, Matthew, Hard, Marjie L., Goulet, Matthew T., McLaughlin, Colleen F., Brantley, Scott J.

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Mass balance and pharmacokinetics of an oral dose of 14C‐napabucasin in healthy adult male subjects von Dai, Xiaoshu, Karol, Michael D., Hitron, Matthew, Hard, Marjie L., Blanchard, John Evan, Eraut, Nicola C. J. E., Rich, Natalie, Gufford, Brandon T.

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Effect of the CYP3A inhibitor ketoconazole on the pharmacokinetics and pharmacodynamics of bortezomib in patients with advanced solid tumors: A prospective, multicenter, open-label... von Venkatakrishnan, Karthik, PhD, Rader, Michael, MD, Ramanathan, Ramesh K., MD, Ramalingam, Suresh, MD, Chen, Eric, MD, PhD, Riordan, William, MA, Trepicchio, William, PhD, Cooper, Michael, MD, Karol, Michael, PhD, von Moltke, Lisa, MD, Neuwirth, Rachel, MS, Egorin, Merrill, MD, Chatta, Gurkamal, MD

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Mass balance and pharmacokinetics of an oral dose of 14 C-napabucasin in healthy adult male subjects von Dai, Xiaoshu, Karol, Michael D, Hitron, Matthew, Hard, Marjie L, Blanchard, John Evan, Eraut, Nicola C J E, Rich, Natalie, Gufford, Brandon T

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Influence of Cardiac Output on Dexmedetomidine Pharmacokinetics von Dutta, Sandeep, Lal, Ritu, Karol, Michael D., Cohen, Theodora, Ebert, Thomas

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Effect of dexmedetomidine on propofol requirements in healthy subjects von Dutta, Sandeep, Karol, Michael D., Cohen, Theodora, Jones, Ron M., Mant, Timothy

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Effect of food on exposure to napabucasin: Data from two phase I studies von Dai, Xiaoshu, Noda, Naoto, Xie, Yuran, Xu, Bo, Hitron, Matthew, Karol, Michael

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Drug-drug interaction (DDI) potential of oral napabucasin in healthy adults von Dai, Xiaoshu, Karol, Michael D., Hitron, Matthew, Hard, Marjie, Goulet, Matthew T., Mclaughlin, Colleen F., Brantley, Scott J.

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Abstract A113: Mass balance and pharmacokinetics of an oral dose of 14C-napabucasin in healthy adult male subjects von Dai, Xiaoshu, Karol, Michael D, Hitron, Matthew, Hard, Marjie, Blanchard, J Evan, Eraut, Nicola, Rich, Natalie, Gufford, Brandon

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The Effects of Oral Doses of Lansoprazole and Omeprazole on Gastric pH von Tolman, Keith G, Sanders, Steven W, Buchi, Kenneth N, Karol, Michael D, Jennings, Dennis E, Ringham, Gary L

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Comparison of the pharmacokinetics of lansoprazole 15- and 30-mg sachets for suspension versus intact capsules von Amer, Fouad, Karol, Michael D., Pan, Wei-Jian, Griffin, Janice S., Lukasik, Nancy L., Locke, Charles S., Chiu, Yi-Lin

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Pharmacokinetic and pharmacodynamic study of two doses of bortezomib in patients with relapsed multiple myeloma von Reece, Donna E, Sullivan, Dan, Lonial, Sagar, Mohrbacher, Ann F, Chatta, Gurkamal, Shustik, Chaim, Burris, Howard III, Venkatakrishnan, Karthik, Neuwirth, Rachel, Riordan, William J, Karol, Michael, von Moltke, Lisa L, Acharya, Milin, Zannikos, Peter, Keith Stewart, A

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Ipilimumab, Pembrolizumab, or Nivolumab in Combination with BBI608 in Patients with Advanced Cancers Treated at MD Anderson Cancer Center von Vo, Henry Hiep, Cartwright, Carrie, Song, I-Wen, Karp, Daniel D, Nogueras Gonzalez, Graciela M, Xie, Yuran, Karol, Michael, Hitron, Matthew, Vining, David, Tsimberidou, Apostolia-Maria

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Mass balance and pharmacokinetics of an oral dose of C-14-napabucasin in healthy adult male subjects von Dai, Xiaoshu, Karol, Michael D., Hitron, Matthew, Hard, Marjie L., Blanchard, John Evan, Eraut, Nicola C. J. E., Rich, Natalie, Gufford, Brandon T.

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Lack of Pharmacokinetic Interaction between Lansoprazole and Intravenously Administered Phenytoin von Karol, Michael D., Locke, Charles S., Cavanaugh, John H.

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Lack of Interaction between Lansoprazole and Propranolol, a Pharmacokinetic and Safety Assessment von Karol, Michael D., Locke, Charles S., Cavanaugh, John H

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Improving Inpatient Care of Adult Cystic Fibrosis Patients von Narasimhan, Mangala, Jaffrey, Fatima, Fulman, Magda, Maniscalo, Patricia, LaVecchia, Geralyn, Karol, Michael, Cohen, Rubin

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